[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr6:80,120,201-83,161,854

Best TWAS P=9.82e-14 · Best GWAS P=3.86e-16 conditioned to 1.48e-10

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum RP11-250B2.6 0.16 0.05 lasso 6 0.06 7.8e-04 6.1 -6.6 3.5e-11 0.05 0.38 0.03 FALSE
2 GTEx Brain Cerebellum RP11-250B2.5 0.43 0.11 lasso 5 0.14 4.7e-05 -6.6 -6.3 2.2e-10 0.27 0.41 0.08 FALSE
3 GTEx Cells Transformed fibroblasts BCKDHB 0.16 0.02 enet 42 0.04 3.7e-04 5.3 7.0 1.9e-12 0.07 0.68 0.02 FALSE
4 GTEx Esophagus Mucosa RP11-250B2.6 0.20 0.16 lasso 7 0.23 3.3e-15 -6.3 -6.8 1.2e-11 0.04 1.00 0.00 FALSE
5 GTEx Heart Atrial Appendage RP11-250B2.6 0.20 0.00 enet 17 0.03 2.6e-02 -3.4 -7.4 9.8e-14 -0.10 0.10 0.04 TRUE
6 GTEx Heart Left Ventricle RP11-250B2.6 0.09 0.00 enet 6 0.02 2.0e-02 6.2 -6.0 2.1e-09 0.06 0.17 0.06 FALSE
7 GTEx Lung RP11-250B2.6 0.09 0.05 enet 16 0.07 5.3e-06 5.4 -7.4 1.5e-13 -0.08 0.84 0.01 TRUE
8 GTEx Muscle Skeletal RP11-250B2.6 0.07 0.04 lasso 5 0.04 4.2e-05 6.9 -7.2 5.4e-13 0.06 0.93 0.02 FALSE
9 GTEx Nerve Tibial BCKDHB 0.18 0.11 lasso 9 0.10 2.4e-07 4.8 5.2 2.6e-07 0.03 1.00 0.00 FALSE
10 GTEx Testis RP11-250B2.5 0.13 0.17 lasso 3 0.14 7.0e-07 -6.4 -6.2 7.3e-10 0.13 0.82 0.01 FALSE
11 GTEx Thyroid BCKDHB 0.17 0.06 lasso 8 0.10 3.4e-08 5.4 6.5 7.9e-11 0.01 1.00 0.00 FALSE
12 GTEx Thyroid RP11-250B2.6 0.11 0.10 lasso 2 0.07 3.2e-06 5.3 -5.3 1.2e-07 -0.08 1.00 0.00 FALSE
13 METSIM Adipose RP11-250B2.6 0.04 0.04 lasso 12 0.02 1.7e-04 6.8 -5.9 2.9e-09 0.09 0.74 0.01 FALSE
14 ROSMAP Brain Pre-frontal Cortex FAM46A 0.08 0.01 blup 495 0.03 2.7e-04 4.3 5.3 1.3e-07 0.15 0.65 0.02 TRUE