[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr6:108,183,628-110,710,018

Best TWAS P=3.5e-10 · Best GWAS P=8.23e-15 conditioned to 3.94e-09

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Aorta	AK9	0.16	0.14	enet	32	0.14	3.7e-08	3.9	5.1	3.1e-07	0.01	0.27	0.72	FALSE
2	GTEx	Artery Coronary	AK9	0.27	0.26	enet	18	0.28	5.2e-10	3.9	5.2	1.7e-07	0.01	0.49	0.50	FALSE
3	GTEx	Artery Tibial	MICAL1	0.08	0.02	lasso	3	0.01	6.5e-02	-6.0	-5.9	2.9e-09	0.00	0.01	0.97	FALSE
4	GTEx	Artery Tibial	AK9	0.13	0.12	enet	18	0.13	3.5e-10	-5.0	5.3	1.1e-07	0.01	0.24	0.76	FALSE
5	GTEx	Artery Tibial	RP11-425D10.10	0.10	0.10	lasso	4	0.10	3.9e-08	-5.9	-5.6	1.9e-08	-0.01	0.02	0.98	FALSE
6	GTEx	Brain Cortex	AK9	0.21	0.03	enet	29	0.16	3.2e-05	-5.1	5.1	3.0e-07	0.02	0.09	0.85	FALSE
7	GTEx	Breast Mammary Tissue	AK9	0.17	0.13	enet	19	0.13	4.0e-07	-4.9	5.2	2.2e-07	0.01	0.02	0.98	FALSE
8	GTEx	Breast Mammary Tissue (Male)	AK9	0.10	0.03	lasso	3	-0.01	5.4e-01	-6.0	6.0	1.9e-09	0.02	0.03	0.55	FALSE
9	GTEx	Breast Mammary Tissue (Female)	RP11-425D10.10	0.14	0.04	lasso	10	0.02	6.5e-02	-5.8	-5.6	2.1e-08	-0.01	0.03	0.55	FALSE
10	GTEx	Colon Transverse	RP11-425D10.10	0.12	0.13	enet	21	0.14	2.2e-07	-5.9	-5.3	1.4e-07	-0.01	0.03	0.97	FALSE
11	GTEx	Esophagus Mucosa	SMPD2	0.17	0.20	lasso	10	0.22	2.2e-14	-5.7	-5.4	5.2e-08	-0.01	0.02	0.98	FALSE
12	GTEx	Esophagus Mucosa	AK9	0.11	0.06	lasso	13	0.04	6.0e-04	-5.1	5.6	2.3e-08	0.02	0.03	0.97	FALSE
13	GTEx	Esophagus Muscularis	CD164	0.04	0.02	enet	6	0.01	1.0e-01	-4.9	-5.3	1.3e-07	-0.01	0.05	0.83	FALSE
14	GTEx	Lung	RP11-425D10.10	0.10	0.08	enet	24	0.07	6.4e-06	-5.8	-5.5	4.1e-08	-0.03	0.02	0.98	FALSE
15	GTEx	Nerve Tibial	AK9	0.18	0.15	enet	26	0.18	1.5e-12	-4.9	5.2	1.7e-07	0.03	0.30	0.69	FALSE
16	GTEx	Ovary	RP11-425D10.10	0.15	0.10	lasso	5	0.02	9.0e-02	-4.9	-5.3	1.4e-07	-0.01	0.03	0.86	FALSE
17	GTEx	Skin Not Sun Exposed Suprapubic	RP11-425D10.10	0.20	0.27	lasso	5	0.27	5.5e-15	-5.0	-5.2	2.7e-07	0.00	0.31	0.68	FALSE
18	GTEx	Skin Sun Exposed Lower leg	SMPD2	0.19	0.19	lasso	12	0.24	1.6e-19	-5.0	-5.2	1.5e-07	0.00	0.28	0.72	FALSE
19	GTEx	Spleen	RP11-425D10.10	0.17	0.04	enet	26	0.12	4.7e-04	-6.0	-5.3	1.5e-07	0.04	0.04	0.84	FALSE
20	GTEx	Testis	MICAL1	0.28	0.02	enet	25	0.02	4.2e-02	-3.7	-6.3	3.5e-10	-0.08	0.03	0.80	TRUE
21	GTEx	Thyroid	PPIL6	0.17	0.05	lasso	4	0.12	4.4e-09	-5.8	5.2	2.6e-07	0.05	0.02	0.98	FALSE
22	GTEx	Vagina	RP11-425D10.10	0.42	0.22	lasso	19	0.17	9.0e-05	-4.9	-5.3	9.3e-08	-0.01	0.03	0.95	FALSE
23	GTEx	Whole Blood	RP11-425D10.10	0.04	0.03	enet	16	0.03	6.2e-04	-5.0	-5.4	5.3e-08	-0.01	0.03	0.96	FALSE
24	METSIM	Adipose	AK9	0.05	0.03	lasso	6	0.02	1.0e-04	-6.0	5.9	4.0e-09	0.02	0.02	0.98	FALSE
25	YFS	Blood	FOXO3	0.03	0.01	lasso	3	0.02	3.2e-07	-6.9	5.9	4.6e-09	-0.77	0.03	0.97	TRUE
26	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SMPD2	0.04	0.04	blup	43	0.05	3.9e-05	-5.9	-5.5	2.9e-08	-0.01	0.01	0.98	FALSE
27	The Cancer Genome Atlas	Esophageal Carcinoma	SMPD2	0.12	0.09	blup	41	0.07	2.6e-03	-5.8	-5.7	1.3e-08	-0.01	0.01	0.88	FALSE
28	The Cancer Genome Atlas	Brain Lower Grade Glioma	AKD1	0.12	0.11	lasso	6	0.12	9.8e-14	-5.1	5.2	2.2e-07	0.01	0.25	0.75	FALSE
29	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZBTB24	0.04	0.05	lasso	4	0.04	7.8e-06	-5.9	5.7	1.0e-08	0.01	0.01	0.99	FALSE
30	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PPIL6	0.07	0.03	blup	53	0.02	5.8e-02	-4.0	5.5	3.0e-08	0.00	0.02	0.60	FALSE
31	The Cancer Genome Atlas	Lung Adenocarcinoma	AKD1	0.05	0.03	blup	122	0.04	1.3e-05	-5.1	5.5	3.0e-08	0.00	0.02	0.98	FALSE
32	The Cancer Genome Atlas	Stomach Adenocarcinoma	SMPD2	0.07	0.07	blup	44	0.08	3.4e-06	-5.9	-5.4	7.7e-08	0.00	0.01	0.99	FALSE
33	The Cancer Genome Atlas	Testicular Germ Cell Tumors	SMPD2	0.23	0.13	lasso	5	0.17	1.4e-06	-5.0	-5.2	2.1e-07	0.00	0.01	0.98	FALSE