[Hub]/) : Traits : Maternal smoking around birth :

chr17:34,146,026-35,644,076

Best TWAS P=4.67e-08 · Best GWAS P=2.58e-07 conditioned to 0.75

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous GGNBP2 0.10 0.11 enet 9 0.11 3.5e-09 4.9 -5.1 3.0e-07 0.93 0.02 0.97 FALSE
2 GTEx Artery Aorta MYO19 0.20 0.16 enet 9 0.15 1.6e-08 -5.0 5.2 2.2e-07 -0.89 0.01 0.98 FALSE
3 GTEx Cells EBV-transformed lymphocytes ZNHIT3 0.31 0.32 enet 9 0.22 1.1e-07 4.9 5.2 2.2e-07 -0.86 0.02 0.98 FALSE
4 GTEx Lung GGNBP2 0.08 0.01 enet 8 0.01 3.3e-02 4.5 -5.2 1.9e-07 0.89 0.03 0.95 FALSE
5 GTEx Muscle Skeletal GGNBP2 0.08 0.06 enet 14 0.05 2.5e-05 -5.1 -5.5 4.7e-08 0.92 0.01 0.99 TRUE
6 GTEx Skin Sun Exposed Lower leg GGNBP2 0.11 0.06 enet 11 0.10 1.3e-08 -5.1 -5.1 3.0e-07 0.94 0.01 0.98 FALSE
7 METSIM Adipose GGNBP2 0.16 0.14 lasso 5 0.14 6.2e-21 4.9 -5.2 2.6e-07 0.91 0.02 0.98 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma GGNBP2 0.10 0.05 lasso 3 0.06 2.5e-04 -5.1 -5.1 2.9e-07 0.94 0.00 0.94 FALSE
9 The Cancer Genome Atlas Prostate Adenocarcinoma GGNBP2 0.02 0.02 enet 4 0.02 6.0e-03 -5.1 -5.2 2.3e-07 0.95 0.00 0.83 FALSE