Best TWAS P=3.6e-09 · Best GWAS P=1.47e-06 conditioned to 0.137
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Heart Atrial Appendage | TMEM161A | 0.29 | 0.1 | enet | 19 | 0.23 | 1.3e-10 | 3.7 | 5.2 | 2.4e-07 | -0.79 | 0.05 | 0.56 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | SUGP1 | 0.03 | 0.0 | blup | 364 | 0.01 | 4.3e-02 | 4.4 | 5.9 | 3.6e-09 | -0.39 | 0.02 | 0.38 | TRUE |