TWAS
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Usage
Models
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Traits
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Traits
:
Maternal smoking around birth
:
←
chr19:18,533,642-20,117,685
Best TWAS P=3.6e-09 · Best GWAS P=1.47e-06 conditioned to 0.137
18.6M
18.8M
19M
19.2M
19.4M
19.6M
19.8M
20M
20.2M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
ROSMAP
Brain Pre-frontal Cortex
SUGP1
0.03
0.0
blup
364
0.01
4.3e-02
4.4
5.9
3.6e-09
-0.39
0.02
0.38
TRUE
1
GTEx
Heart Atrial Appendage
TMEM161A
0.29
0.1
enet
19
0.23
1.3e-10
3.7
5.2
2.4e-07
-0.79
0.05
0.56
TRUE