TWAS hub - TMEM161A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.3988	0.0799	9.8e-08	0.017	NA	0.161	NA	0.158	1.7e-02	NA	1.2e-12	NA	1.9e-12
2	GTEx	Heart Atrial Appendage	0.2880	0.0830	2.0e-05	0.098	NA	0.228	NA	0.172	3.6e-05	NA	1.3e-10	NA	3.5e-08
3	GTEx	Heart Left Ventricle	0.2518	0.0831	7.1e-05	0.056	NA	0.225	NA	0.252	6.4e-04	NA	3.2e-12	NA	1.1e-13
4	GTEx	Muscle Skeletal	0.6361	0.0433	0.0e+00	0.148	NA	0.455	NA	0.441	2.5e-14	NA	2.5e-49	NA	2.3e-47
5	GTEx	Thyroid	0.2380	0.0690	9.3e-07	0.066	NA	0.115	NA	0.116	8.3e-06	NA	4.5e-09	NA	3.6e-09
6	GTEx	Whole Blood	0.0560	0.0300	2.7e-03	0.003	NA	0.003	NA	0.000	1.6e-01	NA	1.4e-01	NA	3.0e-01
7	ROSMAP	Brain Pre-frontal Cortex	0.0948	0.0344	4.7e-04	0.093	0.013	0.090	0.088	0.099	5.6e-12	8.1e-03	1.3e-11	2.4e-11	1.1e-12
8	TCGA	Breast Invasive Carcinoma	0.0372	0.0213	7.9e-03	0.011	0.003	0.010	NA	0.012	2.3e-03	7.2e-02	3.1e-03	NA	1.1e-03
9	TCGA	Kidney Renal Clear Cell Carcinoma	0.0720	0.0330	1.3e-03	0.044	0.022	0.038	NA	0.045	8.9e-06	1.5e-03	3.3e-05	NA	8.2e-06
10	TCGA	Brain Lower Grade Glioma	0.0389	0.0203	5.6e-03	-0.002	0.014	0.009	NA	-0.002	8.7e-01	7.9e-03	2.7e-02	NA	8.8e-01
11	TCGA	Thyroid Carcinoma	0.1560	0.0510	3.7e-10	0.062	0.108	0.085	NA	0.080	1.0e-06	1.2e-10	1.3e-08	NA	3.5e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Maternal smoking around birth	7.6	11.0	26.7	3.5	5.2	4.4	4.6	3.5	-3.4	-2.0	-0.3	-0.8	1.8	3.2
Pain all over the body in last month	3.3	3.5	7.7	2.5	2.4	2.8	2.3	2.3	-0.7	-0.7	0.4	-0.1	1.6	2.2
Age at first live birth	3.0	5.3	14.6	-2.4	-3.2	-2.4	-2.3	-3.1	3.8	0.9	0.0	0.9	-0.7	-2.4
Illness, injury, bereavement, stress in last 2 years	3.0	3.7	7.7	-2.4	0.0	-1.0	-0.1	-2.8	-0.8	-2.8	-2.0	-2.5	-1.7	-2.2
Medication: Levothyroxine sodium	2.9	4.9	11.2	0.8	3.0	2.3	2.1	1.3	-3.4	-3.2	-1.7	-2.2	0.9	1.9
Triglycerides	2.7	4.4	24.8	1.0	-2.2	1.0	-0.0	1.3	5.0	0.1	0.1	1.1	3.0	2.3
Mother’s age at death	2.7	3.4	11.4	-0.2	-2.2	-1.1	-1.6	-1.3	3.4	2.6	1.5	1.7	-1.3	-1.4
Bilateral oophorectomy (both ovaries removed)	2.6	3.1	6.9	2.6	1.5	1.1	1.1	2.2	-0.4	1.3	1.7	2.0	2.6	1.4
Serious illness, injury or assault to yourself	2.6	3.2	6.8	2.4	1.3	1.9	0.8	2.5	0.1	0.8	1.4	1.3	2.6	2.5
Unable to work because of sickness or disability	2.6	3.4	11.6	2.6	1.7	1.9	1.5	3.4	-1.3	0.6	0.8	0.8	0.6	2.5
Medication: Co-codamol	2.4	2.7	5.4	2.3	1.7	1.8	1.7	2.3	-2.2	-0.7	0.3	-0.5	0.6	2.0
Angina (self-reported)	2.4	3.2	9.2	0.1	1.0	1.4	2.9	0.8	1.9	-3.0	-2.5	-1.6	0.5	1.1
Age at last live birth	2.4	3.5	8.5	-2.7	-2.0	-1.5	-0.9	-2.9	2.5	-0.5	-1.3	-0.5	-1.2	-2.3
Pain type(s) experienced in last month: Hip pain	2.4	3.0	8.9	-1.7	-0.3	-1.3	-1.4	-1.2	-1.8	-1.5	-2.0	-1.9	-3.0	-1.7
Blood Platelet Count	2.3	26.7	182.2	2.0	6.6	4.2	3.9	2.3	-13.5	-2.3	-0.2	-1.4	2.5	3.4
Angina	2.2	2.8	8.3	0.1	0.8	1.3	2.6	0.8	1.9	-2.9	-2.4	-1.6	0.5	1.1
Medication: Ramipril	2.2	2.9	8.5	2.9	2.5	2.2	2.2	1.4	-2.0	0.1	0.4	0.7	-0.5	0.7
Medication: Cholesterol lowering	2.2	3.4	25.0	0.9	-1.0	0.0	1.0	1.1	5.0	-1.5	-1.4	-0.3	1.2	1.8
Migraine (self-reported)	2.2	2.7	5.9	0.3	1.8	2.4	2.2	1.5	0.7	-2.1	-1.6	-1.8	1.0	1.2
High cholesterol (Self-reported)	2.2	3.8	32.0	0.2	-2.0	-0.5	0.2	0.2	5.7	-1.5	-1.4	-0.5	0.5	1.0
Risk taking	2.2	3.2	7.0	1.9	1.9	1.7	1.5	2.5	-2.3	-0.0	0.4	0.3	2.0	2.6
LDL Cholesterol	2.1	3.4	11.6	1.1	-1.6	0.4	-0.4	1.5	3.4	0.7	0.5	2.0	3.0	2.3
Exposure to tobacco smoke at home	2.1	2.4	5.2	1.4	2.2	1.3	1.6	2.1	-2.3	0.1	0.9	0.4	1.2	1.8
Mouth/teeth dental problems: Bleeding gums	2.1	2.7	7.1	-1.5	-0.5	-1.1	-0.4	-0.5	2.1	-2.2	-2.5	-2.7	-1.4	-0.6
Breast cancer (self-reported)	2.1	2.4	7.3	0.3	1.9	1.1	1.0	1.1	-2.3	-0.9	0.0	-0.2	2.7	2.5
Breast Cancer	2.0	4.8	44.0	0.1	-0.8	-0.6	-0.9	-0.1	6.6	1.4	1.8	1.3	0.7	-0.3
Age at First Birth	2.0	2.9	7.5	-2.0	-2.7	-2.4	-2.3	-1.5	1.1	0.7	-0.3	0.2	-1.7	-1.4
Prostate Cancer	1.9	2.7	10.8	2.2	1.4	0.7	0.7	1.4	-3.3	1.3	1.6	1.4	0.6	1.7
Body Mass Index (BMI) (2010)	1.9	2.6	5.9	2.2	1.0	1.5	1.4	1.9	2.4	0.8	1.5	1.3	1.8	1.2
Alcohol intake versus 10 years previously	1.9	2.8	9.7	0.2	0.7	-0.2	0.2	1.3	-2.3	-2.3	-1.8	-3.1	-1.1	1.9
Comparative body size at age 10	1.9	5.3	26.8	2.1	0.5	0.2	0.2	1.5	5.2	1.9	2.3	2.7	3.0	0.5
Number of live births	1.8	2.6	6.7	1.4	2.5	1.8	2.6	1.1	-1.8	-1.8	-0.8	-1.1	0.4	0.4
Hypothyroidism/myxoedema (self-reported)	1.8	3.6	11.9	0.9	2.9	1.9	2.2	0.4	-3.5	-2.4	-1.1	-1.1	0.5	1.0
Mouth/teeth dental problems: Loose teeth	1.8	2.1	4.1	-1.6	0.3	-0.3	-0.7	-1.2	-1.9	-1.7	-2.0	-2.0	-1.9	-0.6
Illnesses of siblings: Diabetes	1.8	2.2	10.5	-0.3	-1.0	-1.4	-0.8	-0.8	-3.2	0.8	0.2	0.2	-2.6	-1.6
Father’s age at death	1.7	2.3	5.3	-2.2	-1.6	-1.9	-1.7	-2.3	0.0	0.6	-0.4	0.4	-1.2	-2.2
Chest pain or discomfort	1.7	2.5	7.6	1.6	2.8	1.4	1.8	1.9	0.0	-1.4	-1.1	-0.8	0.5	2.1
Schizophrenia (2014)	1.6	3.5	32.6	0.4	0.7	0.4	1.0	0.7	-5.7	0.1	0.9	0.6	0.9	1.1
Current tobacco smoking	1.6	2.6	6.1	0.5	1.8	1.1	1.0	1.4	-2.1	-2.4	-1.4	-2.5	-0.6	1.8
Happiness	1.6	2.0	7.1	-1.7	-2.7	-1.3	-1.9	-1.0	1.8	-0.3	-1.0	-0.8	-0.6	-0.4
Suffer from ‘nerves’	1.6	2.5	7.5	0.9	-0.4	-0.4	-0.9	2.6	-1.4	1.3	1.5	0.7	2.7	2.4
Eye problems/disorders: Glaucoma	1.6	1.9	5.4	-1.3	-1.7	-1.6	-1.9	-1.0	2.3	0.5	-0.3	-0.1	-1.5	-1.1
Rheumatoid Arthritis	1.5	2.1	10.3	1.6	1.1	1.6	1.4	0.7	-3.2	-0.3	0.7	0.3	1.2	1.3
Mouth/teeth dental problems	1.5	2.3	6.6	1.2	0.8	1.2	0.7	0.2	0.9	1.8	2.3	2.6	2.4	0.6
Depression (self-reported)	1.5	1.8	5.2	0.5	-1.3	-0.8	-1.1	2.3	0.6	1.9	1.2	0.8	0.4	2.0
Breastfed as a baby	1.5	1.8	6.4	1.1	-0.1	-0.1	-1.0	-0.1	-0.5	2.4	2.5	2.2	0.9	0.1
Emphysema/chronic bronchitis	1.5	1.7	4.0	2.0	1.5	1.0	1.2	1.7	0.0	0.9	1.1	1.5	0.9	1.3
Long-standing illness, disability or infirmity	1.5	2.3	8.4	-0.1	1.0	-0.0	0.4	0.3	0.3	-2.9	-2.9	-2.5	-0.8	0.0
Smoking status: Current	1.5	2.3	6.5	0.1	1.5	0.5	0.7	1.0	-2.2	-2.5	-1.3	-2.5	-0.6	1.5
Myopia	1.5	2.1	17.2	-0.1	0.4	0.1	-0.6	0.1	-4.2	1.0	1.5	0.9	1.1	0.3
Hypothyroidism (self reported)	1.4	3.3	8.0	1.4	2.6	1.7	2.4	0.6	-2.8	-2.4	-1.2	-1.0	0.8	1.2
Respiratory disease	1.4	3.0	11.2	1.7	1.2	1.2	0.9	3.2	0.4	0.2	0.0	0.3	2.2	3.3
Diabetes (mother)	1.4	1.8	6.8	0.4	2.1	1.5	1.6	0.8	-2.6	-1.1	-0.7	-0.9	-0.6	-0.2
Qualifications: CSEs or equivalent	1.4	1.9	4.2	1.6	1.7	1.3	2.0	1.8	-0.4	-1.1	0.4	-0.6	0.8	2.0
Glaucoma (self-reported)	1.4	1.6	3.8	-0.8	-1.9	-1.3	-1.8	-1.0	1.6	1.1	0.6	0.5	-1.4	-1.2
Medication: Seretide 50 evohaler	1.4	1.6	3.2	1.7	1.2	1.0	1.2	1.8	0.6	0.5	0.7	1.5	1.5	1.6
Illnesses of father: Heart disease	1.4	1.9	8.6	-0.6	-1.6	-1.0	-1.6	0.3	2.9	1.0	0.5	1.1	1.9	0.4
Average weekly red wine intake	1.4	2.1	6.2	1.0	1.1	1.1	0.8	-0.8	-1.4	2.0	2.0	2.5	1.0	-1.1
Mouth/teeth dental problems: Mouth ulcers	1.4	2.3	10.2	-0.6	-1.5	-1.7	-1.5	-1.4	-3.2	0.2	-0.0	-0.5	-1.8	-1.3
Sensitivity / hurt feelings	1.3	2.2	22.4	0.5	0.7	0.4	0.2	0.7	-4.7	-0.1	-0.1	-0.1	-0.4	0.8
Hearing difficulty/problems: Yes	1.3	2.1	12.5	0.4	0.7	0.5	0.2	1.7	3.5	-1.3	-1.1	-0.8	1.2	1.1
Medication: Metformin	1.3	1.8	6.1	0.3	1.6	1.2	1.4	0.6	-1.7	-2.5	-1.2	-1.6	0.4	0.5
Medication: Simvastatin	1.3	1.8	16.1	0.8	-0.5	-0.0	1.0	0.4	4.0	-0.6	-0.7	0.6	0.7	0.6
Hair/balding pattern: Pattern 3	1.3	2.0	4.2	-0.4	-2.0	-1.8	-1.2	-2.0	1.6	0.9	0.1	0.3	-1.4	-1.9
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.6	6.1	-0.8	-1.4	-2.5	-1.6	0.0	-1.1	-0.3	-1.0	-1.1	-1.8	-0.1
Medication: Amlodipine	1.3	1.8	4.0	2.0	1.6	0.4	0.9	1.8	1.9	0.4	1.0	0.7	0.6	1.9
Chronic bronchitis/emphysema (mother)	1.3	1.5	3.6	1.9	1.6	1.9	1.4	1.8	-0.4	-0.1	-0.3	-0.0	0.2	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.6	4.2	-1.7	-1.2	-1.3	-1.0	-1.3	2.0	-0.0	-0.9	-0.8	-0.5	-1.6
Overall health rating	1.3	2.8	6.9	1.5	1.2	0.4	0.3	2.6	-2.2	-2.1	-1.7	-2.1	-0.6	1.8
Medication: Atorvastatin	1.3	1.6	8.1	0.1	-0.4	0.3	0.3	0.8	2.8	-1.6	-1.7	-1.1	0.8	1.1
Bipolar Disorder or Schizophrenia	1.2	2.9	27.2	-0.7	-0.0	-0.6	-0.1	0.2	-5.2	-0.2	0.6	0.2	1.3	1.3
Type 2 Diabetes (T2D) (2018)	1.2	2.3	5.8	2.4	2.3	1.8	1.8	1.1	-2.2	-0.2	0.6	0.6	0.2	0.6
Hayfever, allergic rhinitis or eczema	1.2	2.5	8.6	-1.5	-2.9	-1.8	-1.9	-1.2	0.7	1.5	0.4	1.1	-0.9	-2.0
Headache pain in last month	1.2	2.1	8.2	-0.6	0.2	-0.7	-0.2	0.9	-2.1	-2.0	-1.9	-2.9	-0.4	1.0
Medication: Gliclazide	1.2	1.4	3.9	1.1	1.5	0.9	1.2	1.0	-2.0	-1.2	-0.5	-1.0	0.5	1.1
Illnesses of father: None of the above (group 1)	1.2	1.5	3.3	1.0	0.4	1.4	1.2	-1.0	-1.3	1.2	1.8	1.6	-0.8	-1.1
Tinnitus: Yes, now most or all of the time	1.2	1.5	5.5	-0.5	0.3	0.4	0.7	0.5	-0.8	-2.3	-1.9	-2.2	-0.1	0.6
Fractured/broken bones in last 5 years	1.2	1.5	6.2	0.8	-0.9	-0.1	-0.2	-0.3	0.6	1.9	1.2	1.3	-2.5	-1.3
Heart disease (siblings)	1.2	1.5	4.5	0.8	0.4	0.1	0.7	1.6	1.6	-0.8	-0.4	-0.6	2.0	2.1
Schizophrenia (2018)	1.1	2.3	24.3	-0.3	0.6	-0.3	0.2	0.1	-4.9	-0.4	0.1	-0.0	0.5	0.7
Alzheimer’s Disease (in father)	1.1	1.2	4.2	1.6	0.3	1.2	1.0	2.0	0.1	-0.2	0.2	-0.1	0.1	1.9
Ovarian Cancer	1.1	1.4	7.3	1.3	-0.5	0.5	0.4	1.8	2.7	-0.2	0.2	-0.5	0.5	1.6
Frequency of depressed mood in last 2 weeks	1.1	1.6	3.5	-0.3	-1.9	-0.9	-1.4	-0.6	1.7	1.8	0.7	1.5	-0.8	-0.8
Ever had hysterectomy (womb removed)	1.1	1.3	3.3	0.9	1.3	1.6	1.2	1.5	-0.5	-0.8	-0.4	0.1	1.8	0.9
Impedance of leg (right)	1.1	5.4	50.1	-1.4	-0.5	-1.1	-1.4	-1.0	-7.1	0.3	-0.1	-0.4	-1.6	-0.1
Supplements: Glucosamine	1.1	1.4	4.2	-1.9	-0.8	-1.2	-1.3	-2.1	0.9	-0.0	-0.7	-0.2	-0.7	-1.6
Impedance of leg (left)	1.1	5.4	51.4	-1.0	-0.5	-0.8	-1.1	-0.9	-7.2	0.5	0.3	0.0	-1.8	-0.2
Qualifications: None of the above	1.1	2.3	10.2	0.8	1.2	-0.0	0.8	1.6	-3.2	-1.6	-1.4	-1.5	-1.4	0.7
Time employed in main current job	1.1	1.2	3.8	0.1	1.9	1.1	0.9	0.3	-1.1	-1.5	-1.7	-1.0	-0.4	-0.4
Qualifications: A levels/AS levels or equivalent	1.1	2.4	6.1	-1.6	-2.5	-1.4	-1.9	-2.1	2.3	0.2	0.0	0.1	0.0	-1.4
Medication: Lansoprazole	1.1	1.3	4.7	0.7	0.7	-0.1	0.4	2.2	-1.4	-0.9	-1.4	-0.8	-0.2	1.7
Peak expiratory flow (PEF)	1.1	2.4	5.1	-0.7	-2.1	-1.6	-1.3	-1.1	1.8	2.3	0.9	1.8	-0.1	-2.0
Exposure to tobacco smoke outside home	1.1	1.4	3.4	0.8	1.2	0.4	0.7	1.8	0.3	-1.4	-0.9	-0.8	1.8	1.6
Leg pain on walking	1.1	1.4	6.1	-1.0	-1.2	-0.6	-1.4	-0.6	-0.3	-1.1	-0.8	-1.6	-2.5	-0.5
Illnesses of father: High blood pressure	1.1	1.3	2.7	-0.9	0.2	-1.5	-0.3	-1.5	-0.6	-0.9	-1.1	-1.4	-1.4	-1.6
Age started oral contraceptive pill	1.1	1.4	4.6	-2.1	-2.0	-1.0	-1.2	-1.5	-0.8	-0.3	-0.9	-0.3	-0.1	-0.9
Ever depressed for a whole week	1.1	1.4	4.7	-1.6	-0.9	-1.1	-0.9	0.6	1.0	-1.0	-0.9	-2.2	-1.0	0.8
Medication: Omeprazole (e.g. Zanprol)	1.1	1.4	4.0	-0.5	-0.7	-0.4	0.1	-0.1	1.1	-2.0	-2.0	-2.0	-0.9	0.3
Pack years of smoking	1.1	1.6	3.6	-1.3	-0.7	-1.9	-1.8	0.4	-1.3	-0.9	-1.6	-1.8	-0.3	-0.1
Worry (Nagel 2018)	1.0	2.2	10.4	1.0	0.2	0.4	0.5	2.1	-3.2	0.5	0.8	0.3	1.8	1.8
Waist Hip Ratio (WHR)	1.0	4.6	12.3	2.1	2.7	2.6	2.7	3.2	1.2	0.1	0.5	-0.2	0.9	3.5
Diabetes (father)	1.0	1.2	2.3	-0.9	-0.7	-1.5	-1.3	-0.5	-1.0	-0.5	-1.0	-1.3	-1.4	-1.3
Townsend deprivation index at recruitment	1.0	1.5	9.3	-0.4	-0.4	-0.9	-0.5	1.3	3.0	-0.3	-1.1	-0.9	-0.4	1.2
Taking other prescription medications	1.0	1.6	11.3	0.2	0.3	0.2	0.2	1.0	-3.4	-1.2	-1.1	-1.0	-0.9	0.8
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	5.5	0.2	0.5	0.3	0.2	2.3	1.5	-0.4	-0.3	-0.7	1.1	1.7
Asthma	1.0	1.9	5.6	1.1	0.2	1.0	0.5	2.3	1.0	0.9	0.6	0.8	2.1	2.4
Birth weight of first child	1.0	1.7	6.5	-1.2	-2.5	-1.2	-2.0	-0.8	1.9	0.9	-0.5	0.7	0.2	-0.4
Medication: Blood pressure	1.0	1.8	4.2	1.5	2.0	1.3	2.0	1.7	0.0	-1.0	-0.7	-0.8	0.1	1.4
Friendships satisfaction	1.0	1.3	5.0	-0.4	-1.7	-1.4	-1.3	-0.9	0.8	-0.0	-0.2	-0.5	-2.2	-0.6
Qualifications: nursing, teaching	1.0	1.5	9.4	-1.0	-1.5	-0.8	-1.0	-0.7	3.1	0.1	-0.4	-0.2	1.1	0.1
Primary Biliary Cirrhosis	0.9	1.3	4.2	0.4	-0.9	-1.6	-1.4	0.0	-0.1	2.0	0.9	1.6	-0.6	-0.9
Blood Eosinophil Count	0.9	6.9	50.6	0.9	3.1	2.0	2.2	1.2	-7.1	-1.3	-0.6	-0.9	0.3	1.4
Number of treatments/medications taken	0.9	1.6	5.1	0.2	0.1	-0.3	0.3	0.5	-1.1	-1.9	-1.9	-1.9	-2.3	-0.0
Medication for hormone replacement therapy	0.9	1.0	3.2	0.6	-0.6	-1.2	-1.0	0.2	-0.4	1.7	1.8	1.4	0.2	-0.3
Pack years adult smoking proportion	0.9	1.4	3.6	-0.9	-0.1	-1.4	-1.3	0.7	-1.6	-1.1	-1.5	-1.9	-0.3	-0.1
Stomach or abdominal pain in last month	0.9	1.1	6.8	1.2	0.3	0.8	0.4	1.0	-2.6	0.1	0.9	0.2	-0.6	0.6
Medication: Atenolol	0.9	1.1	2.6	0.8	0.8	0.2	1.0	1.6	0.4	-1.5	-0.9	-1.4	0.2	1.4
High blood pressure (mother)	0.9	1.3	4.8	-0.8	-0.8	-1.3	-0.8	-0.9	-1.4	-0.7	-0.7	-1.4	-2.2	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	3.3	1.2	-0.1	0.7	-0.0	1.0	1.2	1.8	1.7	1.8	1.1	0.7
Had other major operations	0.9	1.2	4.5	-0.5	1.4	0.3	0.4	0.3	-0.0	-1.7	-2.1	-1.6	0.2	0.4
Diabetes (self-reported)	0.9	1.4	4.0	2.0	1.9	1.0	0.9	1.3	-1.2	0.4	1.3	0.8	0.1	0.2
Mouth/teeth dental problems: Dentures	0.9	1.5	3.2	0.6	1.1	0.9	1.4	1.3	-1.3	-1.8	-1.4	-1.7	-0.5	0.8
Blood clot in the leg (DVT)	0.9	1.2	4.0	1.0	-0.3	-0.7	-0.9	1.6	0.2	0.9	1.0	0.4	1.5	2.0
Medication: Ventolin 100micrograms inhaler	0.9	1.1	4.8	1.1	-0.2	0.2	-0.1	2.0	-0.4	0.6	0.1	0.4	1.3	2.2
Number of children fathered	0.9	1.0	4.9	-0.4	1.0	1.0	0.6	0.0	-0.6	-1.5	-2.2	-1.2	0.3	-0.2
Medication: Omeprazole	0.9	1.1	3.7	-0.6	-0.7	-0.4	-0.1	-0.3	1.3	-1.7	-1.9	-1.7	-0.6	0.2
Number of full sisters	0.9	1.1	1.8	0.9	1.1	1.3	1.3	0.9	-1.2	1.1	1.2	1.1	-0.1	0.4
Had major operations	0.9	1.0	4.1	-1.1	-0.1	0.9	0.6	-0.6	2.0	-1.0	-1.1	-0.9	0.4	-1.0
Asthma (self-reported)	0.9	1.8	6.4	1.2	0.2	1.0	0.5	2.5	0.9	0.8	0.5	0.7	1.7	2.5
Hearing aid user	0.9	1.1	4.1	0.6	-0.2	0.1	-0.2	1.8	1.2	0.3	0.6	0.2	1.5	2.0
Medication: Blood pressure	0.9	1.8	6.2	0.9	2.5	0.9	1.2	1.1	-1.4	-1.8	-1.4	-1.2	-0.2	0.8
Number of operations (self-reported)	0.9	1.4	3.1	1.1	1.6	1.6	1.7	1.2	0.8	-0.9	-0.7	-0.1	1.5	0.7
Basal cell carcinoma (self-reported)	0.9	1.1	2.9	1.2	0.3	1.7	1.5	1.0	-0.1	0.4	0.8	0.9	1.3	1.0
Neuroticism (Nagel 2018)	0.8	1.9	12.8	1.4	0.3	0.5	0.4	2.0	-3.6	0.6	0.1	0.5	0.1	1.2
Supplements: Zinc	0.8	0.8	2.9	-1.7	-1.3	-1.0	-0.5	-1.2	0.2	0.4	-0.4	0.3	0.2	-1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	6.3	1.1	0.3	0.7	0.6	2.5	0.4	-0.4	-0.4	-0.3	0.8	1.8
Birth weight	0.8	1.7	5.2	0.3	-1.0	0.8	0.0	-0.1	2.0	1.9	2.3	1.8	1.0	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	3.7	0.4	1.4	1.2	1.6	-0.1	-1.9	-0.7	-0.5	0.0	-0.6	-0.0
Qualifications: College or University degree	0.8	2.5	11.2	-0.9	-1.6	-1.0	-1.6	-1.3	3.3	1.4	1.1	1.1	1.5	-0.7
Medication: Ibuprofen	0.8	1.0	4.1	-0.2	-0.7	-1.4	-0.7	0.6	-1.3	-0.2	-0.6	-1.0	-2.0	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	2.4	1.5	0.0	-0.0	-0.3	0.8	-1.0	1.4	1.5	1.3	0.7	0.8
Hypertension (Self-reported)	0.8	2.2	5.7	1.5	2.4	1.4	2.2	1.6	0.1	-1.2	-1.0	-1.2	-0.6	1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	2.5	0.6	-0.1	-0.7	-0.4	1.4	0.2	-1.1	-1.4	-1.6	-1.3	0.9
Loneliness, isolation	0.8	1.1	5.8	1.5	0.8	0.7	0.7	2.4	-0.9	-0.1	-0.6	-0.3	-0.1	1.3
Number of self-reported non-cancer illnesses	0.8	1.4	4.4	0.2	-0.2	-0.1	0.0	1.3	-0.3	-1.6	-2.1	-2.0	-1.4	0.8
Medication: Lisinopril	0.8	1.0	2.3	0.2	0.9	0.7	0.6	1.1	1.2	-1.2	-0.6	-1.4	1.0	1.5
Vascular/heart problems diagnosed by doctor	0.8	2.3	5.4	-1.5	-2.1	-1.4	-2.3	-1.7	-0.4	1.6	1.2	1.4	0.6	-1.6
Supplements: Calcium	0.8	0.9	3.1	0.1	0.0	0.7	1.1	-0.6	-1.8	0.6	0.4	1.5	-0.8	-1.3
Deep venous thrombosis (DVT) (self-reported)	0.8	1.1	3.3	0.6	-0.7	-1.0	-1.2	1.4	0.3	0.8	0.8	0.3	1.3	1.8
Alcohol drinker status: Previous	0.8	0.9	2.7	-0.5	-0.9	-1.0	-1.3	-0.4	-1.6	0.0	-0.3	-0.6	-1.6	-0.7
Bipolar Disorder (2018)	0.7	1.0	4.8	-0.7	-0.8	-0.5	-0.9	0.3	-2.2	0.1	0.7	0.4	1.4	1.2
Depressed Affect (Nagel 2018)	0.7	1.6	5.8	1.5	1.1	1.0	0.9	2.4	-2.0	-0.2	-0.6	-0.0	-0.3	1.4
Alzheimer’s Disease (in mother)	0.7	0.8	2.6	-0.8	-0.1	0.2	0.6	-1.0	-0.7	-1.6	-1.4	-1.1	-0.9	-0.4
HbA1C	0.7	0.8	1.4	-1.2	-0.5	-0.0	-0.3	-1.1	0.6	-0.9	-0.7	-1.1	-1.2	-1.1
Cardiovascular Disease	0.7	2.2	5.0	1.8	1.4	1.3	2.2	1.7	2.0	-1.2	-0.4	-0.9	-0.5	1.7
Average weekly spirits intake	0.7	0.9	2.7	-0.1	-0.7	-0.6	-0.2	-1.2	-1.4	0.1	-1.0	0.1	-1.3	-1.7
Severe depression (siblings)	0.7	0.8	2.5	-1.0	-0.9	-0.6	-1.1	-0.7	-1.6	0.8	0.0	0.2	-0.7	-1.3
High blood pressure	0.7	1.9	4.1	1.1	2.0	1.2	2.0	1.4	0.3	-1.5	-1.2	-1.5	-0.8	1.4
Waist circumference	0.7	2.4	6.8	2.0	0.7	0.5	0.6	2.6	2.0	-1.4	-1.6	-1.5	-0.0	2.0
Hearing difficulty/problems with background noise	0.7	1.1	2.8	-0.2	1.3	1.3	0.9	0.3	0.6	-1.7	-1.5	-1.2	-0.3	-0.5
Illnesses of siblings	0.7	1.0	3.7	-0.8	-0.4	0.4	-0.0	-1.7	1.3	0.4	0.3	0.9	-0.6	-1.9
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.9	3.6	0.6	-0.8	0.0	0.2	0.8	1.9	0.6	1.2	0.3	0.7	1.4
Hair/balding pattern: Pattern 4	0.7	1.6	5.5	-0.6	1.0	1.2	1.7	0.4	0.9	-2.4	-1.9	-1.3	0.6	0.0
Pulse wave reflection index	0.7	0.8	3.6	0.7	1.6	1.0	1.9	0.1	1.0	-0.1	-0.5	0.4	-0.2	-0.4
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	3.7	-1.3	-1.0	0.1	-0.7	-1.9	-0.9	0.6	0.7	0.6	-0.5	-1.6
Medication: Paracetamol	0.7	1.2	8.0	0.3	0.7	-0.4	0.3	0.7	-2.8	-0.3	-0.6	-0.8	-1.5	0.4
Health satisfaction	0.7	1.0	2.6	1.0	1.5	1.4	0.4	1.6	0.9	-0.8	-0.4	-0.6	0.4	0.7
Eye problems/disorders: None of the above	0.7	0.8	1.6	1.1	0.9	0.7	1.0	0.6	0.3	0.0	1.2	0.3	1.3	1.0
Medication for pain relief, constipation, heartburn	0.7	1.2	3.0	-0.3	-0.1	0.9	-0.1	-1.7	0.7	1.0	1.5	1.3	1.5	-1.1
Heart disease (mother)	0.7	0.9	1.7	0.8	-0.5	-0.3	-0.0	1.1	1.3	1.2	0.8	1.3	1.1	0.5
Alcohol intake frequency.	0.7	1.5	6.4	-0.0	0.4	0.1	-0.2	0.7	-2.0	-2.1	-1.0	-2.5	0.0	0.5
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.0	-1.3	-0.2	-0.5	-0.3	-1.4	-1.1	-0.8	-0.8	-0.9	-0.5	-1.0
Diabetes diagnosed by doctor	0.7	1.2	3.3	1.7	1.8	1.0	1.3	0.6	-1.6	-0.6	0.2	0.1	-0.8	-0.5
Osteoporosis (self-reported)	0.7	0.9	2.4	1.5	1.2	1.5	1.3	0.5	-0.2	0.4	0.3	1.3	-0.0	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	3.2	1.4	1.1	0.8	1.2	0.5	1.0	1.8	1.7	1.6	0.5	-0.0
Financial situation satisfaction	0.7	0.9	4.8	-0.5	-1.0	-0.7	-1.1	0.5	2.2	-0.7	0.0	-1.1	0.6	0.2
Irritability	0.7	1.2	3.1	0.8	-1.7	0.1	-0.3	1.1	-0.2	1.6	1.2	1.8	0.2	1.1
Diastolic blood pressure, automated reading	0.7	2.0	5.6	1.4	2.4	0.3	1.6	0.8	-1.9	-1.1	-1.0	-1.4	-1.8	0.8
Pain experienced in last month	0.7	1.2	2.8	-0.7	-0.4	-0.1	-0.3	-1.6	1.0	1.1	0.7	1.7	1.6	-1.1
Impedance of whole body	0.7	3.4	29.8	-1.1	-1.1	-0.8	-1.5	-0.3	-5.5	0.5	0.7	0.2	0.6	0.7
Alzheimer’s Disease (including proxy)	0.6	0.9	2.6	-0.0	0.1	0.7	1.1	0.6	-1.0	-1.5	-1.6	-1.1	-0.7	0.7
Type 2 Diabetes (T2D) (2012)	0.6	0.7	5.2	0.7	-0.1	-0.3	-0.3	0.4	-2.3	0.7	0.5	0.5	0.2	0.3
Blood White Count	0.6	4.7	11.2	2.3	3.4	2.0	1.9	2.8	-3.3	-0.5	0.1	-0.9	0.5	2.9
Lung FEV1/FVC ratio	0.6	3.0	11.4	-1.4	-0.5	-1.2	-1.1	-2.2	-0.6	1.2	0.1	0.6	-3.0	-3.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.9	3.6	0.8	1.1	0.9	0.6	1.9	-0.3	-0.1	0.0	-0.1	0.5	1.6
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.4	0.3	-0.0	1.1	1.4	0.8	0.6	-0.5	-0.2	-0.3	0.6	1.6
Chronic bronchitis/emphysema (father)	0.6	0.7	2.2	0.3	-0.1	-0.4	-0.7	1.0	0.8	-0.7	-1.5	-1.1	-0.8	1.2
Hair/balding pattern: Pattern 2	0.6	0.8	4.7	-0.3	-0.2	-0.4	-0.8	0.2	-2.2	0.4	-0.1	-0.6	-1.4	0.5
Financial difficulties in last 2 years	0.6	0.8	3.7	0.7	0.7	0.5	-0.0	1.7	1.0	-0.3	0.0	-0.7	0.0	1.9
Impedance of arm (right)	0.6	2.7	5.8	-1.3	-2.3	-1.3	-2.4	-0.3	-2.1	1.1	1.4	0.9	2.4	0.9
Falls in the last year	0.6	0.8	2.9	-0.8	-0.1	-0.9	-0.4	-0.7	-1.7	0.1	-0.6	-0.2	-1.4	-1.1
Impedance of arm (left)	0.6	2.6	7.2	-1.0	-2.1	-1.1	-2.1	0.1	-2.1	1.2	1.4	0.9	2.7	1.3
Medication for cholesterol, blood pressure or diabetes	0.6	1.1	6.6	-0.7	0.2	0.2	-0.7	-1.0	-2.6	0.7	1.1	0.4	-0.2	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	3.6	0.5	0.2	0.4	-0.7	1.5	0.2	0.6	0.6	0.4	1.9	1.1
Pulse wave peak to peak time	0.6	0.7	1.4	-0.9	-1.1	-0.9	-1.2	-1.1	1.0	-0.2	-0.1	-0.5	0.5	-0.4
Neck or shoulder pain in last month	0.6	0.9	5.0	1.1	0.4	1.1	0.5	0.9	-2.2	0.0	0.4	-0.2	-0.4	0.9
Comparative height size at age 10	0.6	3.2	11.0	0.4	-0.9	-0.4	-1.4	1.2	3.3	2.0	1.6	1.8	2.9	1.4
Leg fat-free mass (right)	0.6	3.2	24.9	1.1	-0.4	0.2	-0.0	1.5	5.0	-0.4	-0.1	-0.1	2.0	1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	3.6	0.3	1.1	0.5	0.7	-0.2	-1.9	0.2	0.2	-0.2	-1.1	-0.4
Commuting to job workplace: Walk	0.6	0.7	3.2	0.2	-0.7	0.3	-0.1	0.0	1.8	1.0	0.8	1.1	-0.5	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	4.2	-0.1	-0.3	-0.1	0.1	0.1	-2.0	-0.8	-0.8	-0.6	-1.3	-0.7
Leg predicted mass (right)	0.6	3.1	24.9	1.1	-0.3	0.1	-0.1	1.5	5.0	-0.4	-0.1	-0.1	1.9	1.4
Miserableness	0.6	1.1	5.4	1.0	0.5	1.0	0.5	2.3	0.2	-0.5	-0.7	0.3	0.9	1.6
Ever taken oral contraceptive pill	0.6	0.6	2.1	1.0	0.7	0.8	0.6	0.6	1.5	0.9	0.6	0.9	-0.3	0.1
Medication: Bendroflumethiazide	0.6	0.9	3.4	-0.0	1.8	0.7	0.7	0.3	-1.0	-1.0	-1.9	-0.7	0.2	-0.0
Alcohol drinker status: Never	0.6	0.7	2.8	0.4	0.6	1.0	0.6	1.3	0.4	-0.6	0.2	-0.3	1.7	0.7
Average weekly beer plus cider intake	0.6	0.9	3.5	0.5	1.0	0.5	-0.3	1.9	-1.1	-0.5	-0.0	-0.9	0.3	1.7
Commuting to job workplace: Cycle	0.6	0.8	3.4	-0.1	0.5	0.7	0.2	0.7	1.5	0.0	-0.4	0.4	1.9	1.1
Schizophrenia vs Biploar Disorder	0.5	0.6	2.7	-0.4	-0.3	0.2	0.5	-0.6	-1.6	-0.4	-0.2	0.0	-1.5	-0.8
Irritable Bowel Disease (IBD)	0.5	1.1	7.8	-0.1	1.0	0.8	0.4	0.4	-2.8	-0.8	-0.8	-0.9	-0.1	0.5
Ulcerative Colitis (UC)	0.5	1.0	5.5	-0.6	0.0	0.6	0.6	0.4	-2.4	-0.9	-1.4	-1.0	-0.1	0.3
Fasting Glucose	0.5	0.6	4.0	0.3	-0.3	0.1	-0.6	0.7	-2.0	-0.0	1.0	-0.2	0.8	0.5
Smoking Status	0.5	1.3	4.3	0.9	1.3	0.4	0.4	1.0	-1.7	-1.3	-0.3	-1.2	0.3	2.1
Allergy or Eczema	0.5	1.3	4.5	-2.1	-2.1	-1.2	-1.3	-0.8	0.1	0.6	-0.1	0.3	0.1	-1.2
Vitamin and mineral supplements	0.5	0.7	5.5	-0.1	-0.7	-0.4	-0.5	-0.5	2.3	0.3	0.3	0.4	0.2	-0.5
Leg fat-free mass (left)	0.5	2.8	20.8	1.1	-0.4	-0.0	-0.1	1.6	4.6	-0.5	-0.3	-0.3	1.9	1.6
Fed-up feelings	0.5	0.9	3.2	0.2	-0.1	0.1	-0.2	0.9	-1.8	-0.9	-1.2	-1.1	-1.4	0.4
Relative age voice broke	0.5	0.8	2.9	0.7	1.2	0.7	0.6	1.0	-0.8	-0.3	0.5	-0.0	0.8	1.7
Leg predicted mass (left)	0.5	2.8	21.0	1.1	-0.4	-0.1	-0.2	1.5	4.6	-0.4	-0.3	-0.3	1.8	1.5
Alcohol usually taken with meals	0.5	0.7	2.7	-0.3	-0.1	-0.1	0.2	-1.4	-0.6	1.1	1.0	1.0	-0.2	-1.6
Allergy	0.5	1.2	4.2	0.6	2.0	0.9	1.5	-0.4	-0.9	-1.6	-0.5	-1.3	-0.4	0.3
Pulse rate	0.5	0.8	5.7	-0.1	-0.2	0.7	-0.1	0.8	-2.4	-0.7	-0.1	-0.8	-0.5	0.7
Prospective memory result	0.5	0.6	3.1	0.3	1.2	0.9	0.3	0.1	-1.8	-0.0	-0.2	-0.3	-0.7	-0.7
Pulse wave Arterial Stiffness index	0.5	0.6	1.4	0.8	1.0	0.7	0.9	1.2	-1.0	0.2	0.1	0.4	-0.4	0.8
Tense / ‘highly strung’	0.5	0.9	2.9	0.2	-0.9	-0.1	-0.0	0.6	-1.3	1.6	0.5	1.7	1.1	-0.2
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.3	-0.6	0.3	1.5	1.4	-0.0	-0.5	-0.6	-0.7	-0.4	-0.9	-0.7
Gout (self-reported)	0.5	0.6	1.3	-0.7	0.1	-1.1	-0.9	-0.5	-1.1	-0.4	-0.1	-0.9	-1.0	-0.9
Worry too long after embarrassment	0.5	0.8	2.1	-0.2	-0.9	-1.1	-1.3	-1.1	-1.4	0.4	0.3	0.6	-0.8	-0.9
Wheeze or whistling in the chest in last year	0.5	0.9	3.9	1.3	0.4	0.3	-0.0	2.0	-0.3	0.3	0.2	-0.2	-0.1	2.0
Supplements: Vitamin C	0.5	0.6	1.5	-0.0	0.0	0.5	0.5	1.0	-1.2	-0.6	-0.9	-0.4	0.8	1.0
Knee pain experienced in last month	0.5	0.7	2.6	-0.4	-0.9	-1.4	-1.4	0.2	0.0	0.4	0.0	-0.6	-1.6	-0.3
Ever had bowel cancer screening	0.5	0.6	2.7	-0.6	0.1	0.4	-0.6	0.4	-0.8	-0.6	-0.0	-0.5	1.6	1.0
Back pain experienced in last month	0.5	0.7	2.7	0.5	-0.4	-0.2	0.5	0.3	1.6	-0.5	-1.0	0.1	-1.6	-0.1
Average weekly champagne plus white wine intake	0.5	0.7	4.1	0.2	0.9	0.7	1.1	-0.1	2.0	0.3	0.5	0.6	0.7	0.3
Coronary Artery Disease (CAD)	0.4	0.5	3.0	-0.1	-0.1	0.3	0.2	0.1	1.7	-0.2	0.4	0.6	1.2	-0.0
HDL Cholesterol	0.4	0.7	2.7	-1.6	-0.6	-1.0	-0.7	-1.2	-0.2	-0.3	-0.9	-0.3	0.1	-0.8
Ulcerative Colitis	0.4	0.6	1.8	0.4	0.7	0.9	0.5	1.4	-1.0	-0.4	-0.7	-0.6	0.0	1.0
BMI	0.4	2.5	10.2	3.2	1.1	1.1	1.8	1.8	2.2	-0.9	-1.0	-0.5	-0.5	0.9
Hand grip strength (left)	0.4	1.1	4.1	-1.8	-1.2	-0.7	-0.6	-2.0	0.5	0.6	0.4	0.3	-0.5	-1.2
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.8	-0.2	0.1	-0.0	-0.5	0.3	0.8	-1.1	-1.3	-1.2	-0.2	0.3
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.6	0.6	-0.2	0.3	0.4	-0.5	-0.8	0.0	-0.0	0.1	-1.3	-1.2
Age when periods started (menarche)	0.4	1.1	6.0	-1.7	-0.5	-0.5	-0.4	-0.9	-2.4	-0.5	-0.5	-0.9	-0.4	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	2.7	0.7	0.6	-0.1	-0.1	1.3	-1.6	0.7	0.8	0.1	1.0	1.6
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	0.8	-0.3	0.8	0.8	0.9	0.4	-0.5	-0.8	0.2	-0.3	0.9	0.2
Multivitamins +/- minerals	0.4	0.5	1.4	-0.0	0.6	0.7	1.2	-0.1	-1.1	-0.6	-0.7	-0.7	-0.8	-0.1
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.4	-0.1	-1.2	-0.3	-1.1	0.2	0.9	0.9	0.4	0.8	0.7	0.2
Neuroticism score	0.4	0.8	3.0	1.0	-0.8	-0.0	-0.5	1.7	-1.2	0.8	0.2	0.8	0.5	1.1
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	2.6	0.8	0.8	0.5	0.1	1.2	-1.6	0.1	-0.3	-0.1	-0.2	0.7
Length of working week for main job	0.4	0.4	1.0	1.0	0.2	0.6	0.8	1.0	-0.5	-0.4	-0.3	-0.4	0.1	0.8
Leg fat percentage (right)	0.4	1.3	4.4	2.1	0.2	-0.4	-0.1	1.3	-1.9	0.1	-0.6	-0.3	-1.9	0.6
Medication: Allopurinol	0.4	0.5	2.7	-0.1	1.0	0.1	-0.0	-0.1	-1.6	-0.7	-0.4	-0.6	-0.6	-0.6
Smoking status: Previous	0.4	0.6	2.0	0.8	0.2	-0.2	-0.2	1.1	-0.0	1.0	0.6	0.7	0.9	1.4
Whole body fat-free mass	0.4	2.2	18.7	0.4	-0.1	0.1	-0.0	0.9	4.3	-0.9	-0.8	-0.7	1.2	1.0
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.6	-0.2	-0.1	-0.4	-0.8	-0.2	0.5	0.8	0.7	1.3	1.1	0.5
Eye problems/disorders: Cataract	0.4	0.5	1.9	-0.2	-0.8	0.2	-0.3	-0.6	-0.8	0.8	0.2	1.4	-0.6	-0.9
Medication for cholesterol	0.4	0.6	1.8	-1.1	-1.3	-0.4	-0.6	-1.1	1.1	0.1	-0.0	-0.3	0.3	-0.2
Whole body water mass	0.4	2.2	19.1	0.4	-0.2	-0.1	-0.2	0.9	4.4	-0.7	-0.7	-0.6	1.1	1.0
Guilty feelings	0.4	0.7	3.5	1.3	0.3	0.5	0.1	0.9	1.9	0.6	-0.1	0.6	-0.6	-0.2
Medication: Paracetamol	0.4	0.7	4.0	0.2	0.3	-0.5	0.4	0.4	-2.0	-0.2	-0.5	-0.6	-1.4	0.0
Basal metabolic rate	0.4	1.9	15.0	0.8	-0.1	0.0	-0.1	1.2	3.9	-0.7	-0.7	-0.6	1.1	1.2
Leg fat percentage (left)	0.4	1.4	5.8	2.4	0.3	-0.2	0.2	1.4	-1.8	0.2	-0.4	-0.0	-2.0	0.5
Crohns Disease (2017)	0.3	0.6	5.4	0.0	1.0	0.2	-0.3	-0.1	-2.3	-0.2	-0.1	-0.5	-0.3	0.1
Reaction Time	0.3	0.6	2.0	0.3	-0.5	-0.9	-0.6	0.1	0.7	1.3	0.8	1.4	0.6	-0.5
Crohns Disease (2012)	0.3	0.4	1.3	0.3	0.9	0.6	0.6	0.6	-1.1	-0.4	-0.5	-0.3	0.2	1.0
Height	0.3	6.3	17.1	-4.1	-4.0	-2.8	-4.1	-1.1	0.2	-0.2	-0.9	-0.8	2.9	0.6
Systolic Blood Pressure	0.3	1.5	4.0	-0.5	1.6	0.4	0.9	0.1	-1.8	-1.6	-1.0	-2.0	-0.9	0.7
Lung FVC	0.3	1.5	2.8	1.2	0.2	0.7	0.8	1.6	-0.3	1.6	1.5	1.6	1.7	1.1
Neuroticism	0.3	0.8	5.2	0.6	-0.5	0.2	-0.3	1.0	-2.3	0.8	0.3	0.8	0.4	0.5
Chronotype (morning person)	0.3	0.8	2.8	-0.3	0.4	0.7	0.3	-1.1	1.2	0.8	0.2	0.6	-1.0	-1.7
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.2	-0.1	0.0	-0.3	-0.9	-0.2	-0.3	1.1	0.5	0.6	-0.7	-0.8
Trunk fat percentage	0.3	1.3	4.4	2.1	-0.9	-0.9	-0.8	2.0	-0.6	0.2	-0.2	-0.2	0.2	1.8
Average weekly fortified wine intake	0.3	0.3	0.8	0.4	0.2	0.8	0.9	0.4	0.6	0.8	0.3	0.5	0.1	-0.4
Body mass index (BMI)	0.3	1.4	7.2	2.7	0.7	0.2	0.8	1.9	1.3	-0.4	-0.7	-0.4	-0.8	0.7
Trunk fat mass	0.3	1.2	4.0	1.8	-0.9	-0.9	-0.9	2.0	0.5	-0.0	-0.4	-0.4	0.4	1.7
Number of incorrect matches in round	0.3	0.5	1.1	-0.6	0.3	-0.9	-0.8	-1.0	-0.4	-0.4	-0.9	-0.6	-0.7	-0.9
Past tobacco smoking	0.3	0.6	2.7	-0.6	-0.0	0.8	0.6	-1.1	0.1	-0.7	-0.5	-0.4	-0.8	-1.6
Nervous feelings	0.3	0.6	4.2	-0.1	-1.2	-0.4	-0.3	0.5	-2.0	0.1	-0.1	-0.2	0.4	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	1.6	0.6	-0.1	-0.3	0.0	0.8	-1.2	0.9	1.1	0.4	0.7	1.3
Fluid intelligence score	0.3	0.7	5.4	-0.2	-1.1	-0.3	-0.6	-0.3	2.3	-0.2	-0.0	0.3	0.7	-0.4
Trunk fat-free mass	0.3	1.8	16.2	-0.1	-0.0	0.0	-0.0	0.5	4.0	-1.0	-1.0	-0.9	0.8	0.6
Hip circumference	0.3	1.2	3.7	0.6	-1.0	-1.2	-0.9	0.2	1.1	-1.6	-1.9	-1.4	-0.5	0.0
Worrier / anxious feelings	0.3	0.5	3.4	0.1	0.1	0.5	0.3	0.5	-1.8	-0.7	-0.7	-0.4	-0.1	0.3
Forced expiratory volume in 1-second (FEV1)	0.3	1.1	3.9	-0.2	-1.2	-0.8	-0.6	-0.2	0.6	2.0	1.4	1.7	0.4	-0.6
Illnesses of mother	0.3	0.4	1.6	0.1	-0.3	0.2	0.3	-0.3	1.1	0.3	0.7	0.8	1.3	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	3.4	0.2	-0.4	-0.1	-0.3	-0.2	1.1	1.8	1.5	1.5	0.7	-0.5
Arm fat mass (right)	0.3	1.3	5.0	2.2	0.0	-0.3	0.1	2.1	1.4	-0.2	-0.4	-0.4	0.4	1.5
Trunk predicted mass	0.3	1.8	15.8	-0.1	-0.0	0.0	-0.0	0.5	4.0	-1.0	-1.0	-0.9	0.9	0.6
Standing height	0.3	2.6	6.8	-2.1	-2.0	-1.1	-2.4	-0.4	1.9	-0.2	-0.2	-0.4	2.6	1.2
Loud music exposure frequency	0.3	0.3	1.2	-0.3	-1.1	-0.5	-0.6	-0.7	0.2	0.4	0.3	0.4	-0.2	-0.6
High blood pressure (siblings)	0.3	0.5	2.2	-0.1	0.3	-0.3	-0.4	0.8	-0.8	-0.3	-0.5	-1.0	0.6	1.5
Body fat percentage	0.3	1.0	4.3	2.1	-0.6	-0.8	-0.5	1.7	-0.9	0.1	-0.3	-0.2	-0.6	1.2
Number of full brothers	0.3	0.4	1.2	1.0	0.4	-0.1	-0.0	1.1	-0.8	0.3	0.6	0.1	0.4	0.6
Mean time to correctly identify matches	0.3	0.5	1.5	0.3	-0.3	-0.6	-0.3	-0.0	0.9	1.2	0.6	1.2	0.2	-0.6
Whole body fat mass	0.3	1.1	4.1	2.0	-0.5	-0.6	-0.4	2.0	0.7	-0.1	-0.4	-0.4	-0.0	1.5
Pulse rate, automated reading	0.3	1.0	3.0	-0.5	0.0	-0.3	-0.8	0.7	-1.6	-1.5	-1.0	-1.7	-0.1	1.0
Family relationship satisfaction	0.3	0.4	1.6	-0.3	-0.8	-0.6	-1.2	-0.2	0.5	0.2	0.0	-0.4	-0.9	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	2.1	-0.9	-1.4	-0.2	-1.5	-0.2	-1.0	0.8	0.5	0.2	0.1	-0.0
Arm fat percentage (left)	0.3	1.1	5.0	2.2	-0.5	-0.6	-0.2	2.0	0.7	0.2	-0.1	-0.1	0.2	1.4
Mood swings	0.3	0.5	1.4	0.1	-1.2	-0.8	-0.6	0.6	-1.0	0.2	-0.4	0.2	-1.1	0.3
Osteoarthritis (self-reported)	0.3	0.4	2.3	-0.2	-0.6	-0.2	-0.3	0.5	-1.5	-0.4	-0.9	-0.5	-0.7	0.2
Medication: Aspirin	0.3	0.4	2.4	0.7	0.6	0.2	0.7	0.6	1.5	-0.3	-0.3	-0.0	-0.5	-0.1
Arm fat mass (left)	0.3	1.1	4.1	2.0	-0.2	-0.5	-0.2	1.9	1.4	-0.2	-0.5	-0.4	0.3	1.4
Commuting to job workplace: Public transport	0.3	0.4	2.4	0.2	-0.4	1.0	0.6	0.3	1.6	-0.1	-0.0	0.3	0.2	-0.4
Ever smoked	0.3	0.5	1.2	0.2	0.2	-1.0	-0.8	0.8	0.6	0.4	0.1	0.2	1.1	1.1
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.8	0.1	-0.0	0.2	-0.6	0.6	0.9	0.7	-0.1	0.6	0.7	-0.4
Intelligence (Savage-Jansen 2018)	0.2	0.6	1.7	-0.7	-1.0	-0.9	-0.6	-0.7	1.3	-0.9	-0.6	-0.1	0.6	-0.1
Major Depression (MDD)	0.2	0.3	1.5	0.0	0.9	0.0	0.0	1.2	0.9	0.0	0.0	0.0	0.0	0.0
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.8	-0.6	-0.9	-1.0	-0.6	-0.7	1.3	-0.6	-0.5	-0.1	-0.1	-0.7
Mean Putamen Volume	0.2	0.2	1.6	-0.6	0.3	0.0	-0.2	-0.1	-1.3	0.1	-0.2	0.2	0.3	-0.2
Lupus	0.2	0.3	0.8	-0.6	0.0	0.2	0.3	-0.1	-0.3	-0.9	-0.4	-0.7	0.8	0.5
Neuroticism (2016)	0.2	0.3	1.0	0.3	-0.2	-0.6	-0.6	0.6	-1.0	0.7	0.5	0.6	-0.3	0.3
Blood Red Count	0.2	1.7	5.5	1.4	1.2	-0.5	-0.1	0.9	1.5	2.3	1.3	0.8	-1.8	-0.9
Heel T-Score	0.2	1.9	12.5	0.1	0.6	-1.0	-0.5	0.5	-3.5	-1.0	-1.3	-1.6	-0.9	0.1
Tanning	0.2	2.9	7.6	2.8	2.2	1.8	1.4	2.1	0.3	0.5	0.9	1.4	1.5	2.0
Hand grip strength (right)	0.2	0.5	2.1	-0.8	-0.3	0.4	-0.1	-0.7	1.0	1.0	1.4	0.4	0.0	0.1
Had menopause	0.2	0.3	1.0	0.4	0.2	-0.0	0.1	0.0	0.6	1.0	0.5	1.0	-0.7	-0.5
Forced vital capacity (FVC)	0.2	0.9	2.2	-0.2	-1.3	-0.4	-0.3	0.1	1.1	1.4	1.2	1.5	1.1	0.2
Weight	0.2	1.2	5.0	1.6	-0.4	-0.3	-0.4	1.6	2.2	-0.5	-0.7	-0.6	0.4	1.2
Arm fat percentage (right)	0.2	1.0	4.7	2.2	-0.4	-0.6	-0.3	1.9	0.7	0.1	-0.1	-0.1	0.0	1.2
Lung cancer (father)	0.2	0.2	1.0	0.1	0.3	0.2	0.3	-0.0	-0.7	-0.2	-1.0	-0.1	-0.8	-0.4
Forced vital capacity (FVC), Best measure	0.2	0.8	2.3	-0.1	-0.5	0.1	-0.1	0.2	1.5	1.0	1.0	1.0	1.5	0.7
Arm fat-free mass (right)	0.2	1.1	6.6	0.6	0.4	0.2	0.3	0.9	2.6	-1.1	-1.1	-1.0	-0.0	0.8
Shortness of breath walking on level ground	0.2	0.2	1.5	0.3	0.4	-0.0	0.3	0.5	0.1	-0.2	-0.0	-0.5	-1.2	-0.0
Leg fat mass (right)	0.2	0.9	4.3	2.1	-0.1	-0.5	-0.2	1.7	-0.0	-0.0	-0.5	-0.3	-0.9	1.1
Arm predicted mass (right)	0.2	1.2	7.1	0.8	0.4	0.2	0.3	1.1	2.7	-0.9	-1.0	-0.9	0.0	1.1
Medication: Aspirin	0.2	0.3	1.7	0.4	0.6	0.3	0.7	0.5	1.3	-0.2	-0.3	0.2	-0.4	-0.4
Mineral and other dietary supplements	0.2	0.2	1.5	0.1	-0.5	-0.4	-0.1	-0.2	-1.2	-0.1	-0.2	-0.5	-0.5	-0.2
Supplements: Fish oil (including cod liver oil)	0.2	0.3	1.0	0.3	0.2	0.2	-0.0	0.4	1.0	0.7	1.0	0.5	0.1	0.6
Arm fat-free mass (left)	0.2	1.1	6.3	0.7	0.5	0.3	0.3	0.9	2.5	-1.0	-1.1	-1.0	0.1	0.8
Cholesterol lowering medication	0.2	0.2	0.9	0.2	-0.4	-0.0	0.3	0.2	0.8	-0.9	-0.9	-0.0	0.1	0.1
Leg fat mass (left)	0.2	0.9	4.8	2.2	-0.1	-0.4	-0.1	1.7	0.1	0.2	-0.3	-0.0	-1.0	1.0
Arm predicted mass (left)	0.2	0.9	5.6	0.5	0.1	-0.1	-0.0	0.7	2.4	-0.9	-1.1	-1.0	-0.2	0.7
Depression (Nagel 2018)	0.1	0.2	1.1	0.2	0.1	0.2	0.2	1.1	0.2	-0.1	-0.7	-0.1	-0.2	0.8
Relative age of first facial hair	0.1	0.3	1.0	0.6	1.0	0.5	0.5	-0.3	-0.5	0.2	0.1	0.5	-0.7	-0.0
Systolic blood pressure, automated reading	0.1	0.4	1.4	0.6	-0.5	-1.2	-0.4	0.2	-0.7	0.9	0.5	0.2	-0.8	0.4
Sitting height	0.1	0.9	2.3	-0.7	-1.1	-0.8	-1.3	0.1	-1.2	-0.6	-0.6	-0.2	1.5	1.3
Heart attack	0.1	0.1	0.5	-0.0	-0.2	0.1	0.5	0.2	-0.7	-0.2	-0.6	0.2	-0.3	-0.0
Noisy workplace	0.1	0.2	0.6	-0.4	0.1	0.4	0.2	-0.1	0.1	-0.7	-0.8	-0.4	0.5	0.3
Wears glasses or contact lenses	0.1	0.2	0.6	-0.0	-0.0	0.6	0.3	-0.3	-0.6	-0.4	-0.7	-0.3	-0.3	0.0
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.5	-0.2	-0.4	-0.2	0.3	0.0	-0.5	-0.1	-0.7	0.2	-0.5	-0.3
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.9	4.2	-0.8	0.0	-0.3	-0.1	-0.5	0.4	-0.6	-1.0	-1.4	-2.1	-1.2

Hub : Genes

TMEM161A

Models

Trait associations