[Hub]/) : Traits : Sensitivity / hurt feelings : ← →

chr8:10,056,664-11,860,845

Best TWAS P=7.6e-12 · Best GWAS P=7.47e-11 conditioned to 0.109

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
50	ROSMAP	Brain Pre-frontal Cortex	XKR6	0.11	0.10	enet	23	0.13	1.2e-16	5.8	-6.8	7.6e-12	0.82	0.14	0.86	TRUE
14	GTEx	Cells EBV-transformed lymphocytes	AF131215.2	0.20	0.10	enet	14	0.11	1.5e-04	5.8	-6.8	1.3e-11	0.85	0.21	0.74	FALSE
37	GTEx	Skin Sun Exposed Lower leg	AF131215.9	0.19	0.17	enet	29	0.21	3.9e-17	5.8	-6.7	2.8e-11	0.82	0.36	0.64	FALSE
44	GTEx	Thyroid	AF131215.9	0.11	0.08	enet	16	0.17	4.7e-13	5.9	-6.6	5.0e-11	0.86	0.12	0.88	FALSE
22	GTEx	Esophagus Mucosa	AF131215.9	0.18	0.16	lasso	14	0.19	1.6e-12	-5.8	-6.5	8.2e-11	0.90	0.03	0.97	FALSE
5	GTEx	Adrenal Gland	AF131215.9	0.18	0.16	lasso	10	0.18	3.5e-07	-6.1	-6.5	1.0e-10	0.93	0.03	0.97	FALSE
33	GTEx	Prostate	AF131215.2	0.18	0.02	lasso	6	0.02	9.6e-02	-5.7	-6.5	1.1e-10	0.77	0.10	0.37	FALSE
4	GTEx	Adrenal Gland	AF131215.2	0.20	0.16	enet	12	0.13	2.2e-05	-6.1	-6.4	1.2e-10	0.96	0.02	0.98	FALSE
7	GTEx	Artery Aorta	AF131215.9	0.13	0.05	lasso	6	0.07	1.3e-04	-6.5	-6.4	1.2e-10	0.94	0.01	0.99	FALSE
51	ROSMAP	Brain Pre-frontal Cortex	AF131215.3	0.08	0.10	lasso	7	0.12	8.3e-16	-6.1	-6.3	2.2e-10	0.88	0.08	0.92	FALSE
29	GTEx	Nerve Tibial	AF131215.2	0.19	0.18	lasso	12	0.23	3.5e-16	5.2	-6.3	2.4e-10	0.88	0.04	0.96	FALSE
34	GTEx	Skin Not Sun Exposed Suprapubic	AF131215.2	0.16	0.11	enet	21	0.20	3.9e-11	5.2	-6.3	2.4e-10	0.87	0.23	0.77	FALSE
32	GTEx	Pancreas	AF131215.9	0.25	0.24	enet	14	0.22	1.0e-09	-6.5	-6.3	3.3e-10	0.93	0.01	0.99	FALSE
43	GTEx	Thyroid	AF131215.2	0.11	0.15	enet	17	0.18	1.2e-13	5.2	-6.3	3.3e-10	0.82	0.40	0.60	FALSE
2	GTEx	Adipose Visceral Omentum	AF131215.2	0.12	0.08	lasso	6	0.06	4.6e-04	-5.8	-6.2	4.3e-10	0.85	0.12	0.86	FALSE
26	GTEx	Heart Left Ventricle	AF131215.9	0.07	0.10	enet	8	0.10	9.4e-06	5.8	-6.2	4.8e-10	0.84	0.06	0.93	FALSE
35	GTEx	Skin Not Sun Exposed Suprapubic	AF131215.9	0.17	0.14	lasso	8	0.19	9.4e-11	5.8	-6.2	5.5e-10	0.86	0.10	0.90	FALSE
9	GTEx	Brain Cerebellar Hemisphere	AF131215.2	0.15	0.17	lasso	3	0.09	3.0e-03	5.8	-6.2	7.1e-10	0.80	0.13	0.57	FALSE
3	GTEx	Adipose Visceral Omentum	AF131215.9	0.18	0.16	lasso	7	0.16	2.0e-08	-5.8	-6.2	7.4e-10	0.90	0.04	0.96	FALSE
31	GTEx	Pancreas	AF131215.2	0.16	0.16	enet	17	0.15	9.1e-07	5.9	-6.1	8.1e-10	0.86	0.05	0.95	FALSE
6	GTEx	Artery Aorta	AF131215.2	0.09	0.09	lasso	7	0.08	2.0e-05	4.8	-6.1	9.4e-10	0.91	0.04	0.96	FALSE
15	GTEx	Cells EBV-transformed lymphocytes	AF131215.9	0.20	0.15	enet	19	0.13	5.6e-05	5.8	-6.1	1.2e-09	0.76	0.18	0.76	FALSE
11	GTEx	Breast Mammary Tissue	AF131215.9	0.10	0.10	lasso	8	0.12	8.7e-07	5.6	-6.0	1.4e-09	0.82	0.23	0.76	FALSE
17	GTEx	Colon Sigmoid	AF131215.9	0.11	0.17	enet	5	0.09	4.9e-04	5.9	-6.0	1.5e-09	0.81	0.15	0.67	FALSE
25	GTEx	Heart Left Ventricle	AF131215.2	0.05	0.01	enet	11	0.01	1.5e-01	-5.9	-6.0	1.6e-09	0.83	0.04	0.92	FALSE
40	GTEx	Spleen	AF131215.2	0.16	0.08	enet	14	0.06	1.1e-02	5.8	-6.0	1.9e-09	0.85	0.10	0.76	FALSE
36	GTEx	Skin Sun Exposed Lower leg	AF131215.2	0.14	0.11	lasso	9	0.16	4.3e-13	5.2	-6.0	2.0e-09	0.83	0.69	0.31	FALSE
24	GTEx	Esophagus Muscularis	AF131215.9	0.14	0.17	enet	16	0.17	1.6e-10	5.9	-6.0	2.4e-09	0.82	0.14	0.86	FALSE
52	ROSMAP	Brain Pre-frontal Cortex	AF131215.2	0.49	0.57	lasso	7	0.57	9.0e-89	5.8	-5.9	3.2e-09	0.79	0.19	0.81	FALSE
27	GTEx	Lung	AF131215.2	0.12	0.08	lasso	5	0.08	1.0e-06	5.8	-5.9	3.6e-09	0.78	0.14	0.86	FALSE
28	GTEx	Lung	AF131215.9	0.15	0.18	lasso	4	0.15	1.5e-11	5.8	-5.9	4.2e-09	0.78	0.22	0.78	FALSE
45	GTEx	Uterus	AF131215.2	0.17	0.07	enet	13	0.09	7.1e-03	-6.1	-5.8	5.2e-09	0.89	0.06	0.77	FALSE
30	GTEx	Nerve Tibial	AF131215.9	0.17	0.17	lasso	4	0.18	5.0e-13	5.8	-5.8	5.6e-09	0.78	0.20	0.80	FALSE
47	GTEx	Vagina	AF131215.9	0.21	0.11	lasso	9	0.08	6.3e-03	-5.5	-5.8	5.6e-09	0.89	0.10	0.81	FALSE
19	GTEx	Colon Transverse	AF131215.9	0.12	0.14	enet	18	0.12	4.0e-06	5.8	-5.8	6.1e-09	0.82	0.05	0.95	FALSE
21	GTEx	Esophagus Mucosa	AF131215.2	0.15	0.14	enet	15	0.18	4.3e-12	5.2	-5.8	7.4e-09	0.81	0.69	0.31	FALSE
8	GTEx	Artery Coronary	AF131215.9	0.39	-0.01	lasso	5	-0.01	6.6e-01	-2.0	-5.7	1.4e-08	0.42	0.06	0.25	FALSE
16	GTEx	Colon Sigmoid	AF131215.2	0.10	0.00	enet	7	0.02	5.0e-02	-4.9	-5.7	1.5e-08	0.81	0.12	0.55	FALSE
57	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	AMAC1L2	0.03	0.03	blup	55	0.04	3.0e-05	-5.6	5.6	1.8e-08	-0.78	0.01	0.99	FALSE
60	The Cancer Genome Atlas	Thyroid Carcinoma	TDH	0.08	0.08	blup	67	0.09	8.1e-09	-5.7	5.6	2.1e-08	-0.67	0.01	0.99	FALSE
46	GTEx	Uterus	AF131215.9	0.16	-0.01	enet	18	0.03	7.5e-02	-5.5	-5.5	3.3e-08	0.79	0.08	0.66	FALSE
56	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	AMAC1L2	0.04	0.00	blup	55	0.02	2.6e-02	4.9	5.5	4.5e-08	-0.74	0.02	0.61	FALSE
23	GTEx	Esophagus Muscularis	AF131215.2	0.10	0.08	lasso	5	0.09	2.3e-06	5.2	-5.4	5.6e-08	0.76	0.63	0.35	FALSE
48	GTEx	Whole Blood	AF131215.9	0.16	0.00	enet	19	0.01	3.8e-02	5.3	-5.4	5.9e-08	0.66	0.13	0.68	FALSE
38	GTEx	Small Intestine Terminal Ileum	AF131215.2	0.14	0.07	lasso	3	0.07	1.1e-02	4.6	-5.4	6.2e-08	0.81	0.10	0.60	FALSE
10	GTEx	Breast Mammary Tissue	AF131215.2	0.16	0.15	lasso	6	0.12	1.1e-06	4.8	-5.4	6.3e-08	0.84	0.47	0.50	FALSE
49	ROSMAP	Brain Pre-frontal Cortex	MTMR9	0.07	0.06	enet	16	0.08	9.5e-11	4.7	5.4	7.4e-08	-0.72	0.98	0.02	FALSE
58	The Cancer Genome Atlas	Prostate Adenocarcinoma	AMAC1L2	0.04	0.04	blup	55	0.05	1.2e-05	-5.2	5.4	7.8e-08	-0.74	0.02	0.97	FALSE
55	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TDH	0.05	0.01	blup	67	0.04	1.3e-05	-5.5	5.3	8.8e-08	-0.70	0.02	0.98	FALSE
39	GTEx	Small Intestine Terminal Ileum	AF131215.9	0.14	0.11	enet	16	0.06	1.6e-02	4.8	-5.3	9.3e-08	0.75	0.15	0.28	FALSE
41	GTEx	Spleen	AF131215.9	0.34	0.23	enet	16	0.15	1.2e-04	-5.7	-5.3	9.6e-08	0.84	0.06	0.92	FALSE
12	GTEx	Breast Mammary Tissue (Female)	AF131215.2	0.04	-0.01	lasso	2	0.00	4.8e-01	5.6	-5.3	1.1e-07	0.72	0.07	0.12	FALSE
18	GTEx	Colon Transverse	AF131215.2	0.15	0.09	enet	32	0.07	3.1e-04	-6.5	-5.3	1.4e-07	0.79	0.02	0.97	FALSE
59	The Cancer Genome Atlas	Prostate Adenocarcinoma	TDH	0.06	0.02	blup	67	0.06	1.5e-06	3.3	5.3	1.4e-07	-0.68	0.02	0.98	FALSE
13	GTEx	Breast Mammary Tissue (Female)	AF131215.9	0.04	-0.01	enet	6	0.02	7.3e-02	4.0	-5.2	1.7e-07	0.70	0.08	0.14	FALSE
42	GTEx	Testis	AF131215.9	0.12	0.21	lasso	4	0.14	5.6e-07	5.2	-5.2	2.0e-07	0.72	0.47	0.53	FALSE
54	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	AMAC1L2	0.03	0.02	blup	55	0.03	1.8e-04	-4.9	5.2	2.0e-07	-0.68	0.03	0.93	FALSE
53	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	AMAC1L2	0.05	0.05	blup	55	0.05	2.9e-05	4.9	5.2	2.2e-07	-0.70	0.19	0.80	FALSE
1	GTEx	Adipose Subcutaneous	AF131215.2	0.24	0.15	lasso	7	0.14	3.5e-11	4.8	-5.2	2.5e-07	0.84	0.26	0.74	FALSE
20	GTEx	Esophagus Gastroesophageal Junction	AF131215.2	0.13	0.06	enet	10	0.11	6.4e-05	-5.7	-5.2	2.6e-07	0.85	0.15	0.74	FALSE