[Hub]/) : Traits : Sensitivity / hurt feelings :

chr8:8,092,025-9,669,775

Best TWAS P=1.4e-09 · Best GWAS P=6.59e-09 conditioned to 0.0128

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ERI1 0.06 0.04 lasso 3 0.04 9.0e-06 4.8 5.1 3.0e-07 -0.46 0.40 0.60 FALSE
2 GTEx Artery Aorta ERI1 0.11 0.08 lasso 5 0.10 5.1e-06 -5.2 5.4 5.9e-08 -0.72 0.06 0.94 FALSE
3 GTEx Artery Tibial ERI1 0.05 0.02 lasso 7 0.01 3.2e-02 -4.9 5.5 3.3e-08 -0.86 0.11 0.79 FALSE
4 GTEx Brain Cerebellar Hemisphere FAM86B3P 0.28 0.27 lasso 8 0.28 5.4e-08 -5.4 5.5 3.1e-08 -0.76 0.10 0.88 FALSE
5 GTEx Brain Cerebellum FAM86B3P 0.19 0.14 lasso 5 0.16 1.8e-05 -4.6 5.2 1.6e-07 -0.74 0.24 0.73 FALSE
6 GTEx Brain Cortex FAM86B3P 0.14 0.05 enet 9 0.07 5.1e-03 -4.8 5.7 9.5e-09 -0.72 0.08 0.66 FALSE
7 GTEx Cells Transformed fibroblasts ERI1 0.34 0.35 lasso 7 0.35 1.9e-27 -5.2 5.7 1.6e-08 -0.71 0.12 0.88 FALSE
8 GTEx Cells Transformed fibroblasts FAM86B3P 0.23 0.33 lasso 11 0.38 8.4e-30 -4.5 -5.5 3.3e-08 0.74 0.70 0.29 FALSE
9 GTEx Esophagus Mucosa FAM86B3P 0.22 0.17 lasso 8 0.19 1.7e-12 -4.5 -5.2 2.3e-07 0.75 0.70 0.30 FALSE
10 GTEx Esophagus Muscularis ERI1 0.12 0.09 enet 13 0.08 7.7e-06 -4.9 5.9 4.7e-09 -0.81 0.15 0.85 FALSE
11 GTEx Lung ERI1 0.13 0.07 lasso 6 0.09 2.7e-07 4.4 5.2 1.9e-07 -0.76 0.22 0.78 FALSE
12 GTEx Muscle Skeletal MFHAS1 0.07 0.04 lasso 4 0.04 1.4e-04 -4.2 -5.3 9.8e-08 0.80 0.18 0.80 FALSE
13 GTEx Nerve Tibial ERI1 0.07 0.01 enet 16 0.01 4.2e-02 4.8 5.3 1.5e-07 -0.78 0.15 0.59 FALSE
14 GTEx Pancreas ERI1 0.08 0.00 enet 16 0.04 6.6e-03 -4.7 6.0 2.5e-09 -0.63 0.15 0.32 FALSE
15 GTEx Pituitary FAM86B3P 0.13 0.15 lasso 4 0.13 3.5e-04 5.7 6.1 1.4e-09 -0.64 0.03 0.90 TRUE
16 GTEx Thyroid SGK223 0.19 0.35 enet 16 0.36 1.1e-28 -4.7 5.4 5.7e-08 -0.81 0.71 0.28 FALSE
17 NTR Blood MFHAS1 0.02 0.01 blup 759 0.01 2.9e-04 -5.4 -5.6 1.8e-08 0.81 0.09 0.91 FALSE
18 ROSMAP Brain Pre-frontal Cortex FAM85B 0.16 0.23 enet 18 0.22 1.8e-28 -4.5 5.3 1.4e-07 -0.74 0.78 0.21 FALSE
19 The Cancer Genome Atlas Bladder Urothelial Carcinoma ERI1 0.05 0.01 blup 72 0.01 5.0e-02 -5.2 5.6 2.3e-08 -0.60 0.02 0.60 FALSE
20 The Cancer Genome Atlas Brain Lower Grade Glioma FLJ10661 0.21 0.26 lasso 9 0.30 2.3e-34 -4.5 5.5 4.4e-08 -0.70 0.55 0.44 FALSE
21 The Cancer Genome Atlas Liver Hepatocellular Carcinoma FLJ10661 0.09 0.07 blup 41 0.07 3.6e-04 5.2 -5.5 4.4e-08 0.68 0.02 0.82 FALSE
22 The Cancer Genome Atlas Lung Adenocarcinoma ERI1 0.06 0.04 blup 72 0.04 1.5e-05 -5.3 5.9 2.8e-09 -0.65 0.03 0.96 FALSE
23 The Cancer Genome Atlas Pancreatic Adenocarcinoma FLJ10661 0.17 0.11 enet 10 0.16 3.3e-07 5.5 -5.3 1.3e-07 0.66 0.01 0.98 FALSE
24 The Cancer Genome Atlas Thyroid Carcinoma SGK223 0.16 0.20 enet 14 0.22 6.1e-21 5.6 5.5 3.9e-08 -0.70 0.01 0.99 FALSE