Best TWAS P=6.69e-09 · Best GWAS P=2.04e-07 conditioned to 0.693
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Muscularis | MADD | 0.13 | 0.07 | enet | 8 | 0.11 | 2.0e-07 | 3.9 | -5.2 | 2.2e-07 | -0.80 | 0.01 | 0.98 | FALSE |
2 | GTEx | Ovary | PACSIN3 | 0.23 | 0.13 | lasso | 11 | 0.16 | 8.3e-05 | -3.0 | -5.2 | 2.5e-07 | -0.42 | 0.04 | 0.30 | TRUE |
3 | GTEx | Pituitary | MADD | 0.42 | 0.32 | lasso | 6 | 0.39 | 8.9e-11 | 5.2 | -5.8 | 6.7e-09 | -0.89 | 0.01 | 0.99 | TRUE |