[Hub]/) : Traits : Nervous feelings : ← →

chr14:74,424,938-76,089,054

Best TWAS P=5.83e-11 · Best GWAS P=2.43e-09 conditioned to 0.502

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DLST 0.09 0.11 lasso 2 0.11 4.0e-13 -5.8 6.0 2.0e-09 -0.95 0.02 0.98 FALSE
2 CommonMind Brain Pre-frontal Cortex RPS6KL1 0.04 0.02 lasso 5 0.02 4.8e-04 5.0 -5.2 2.3e-07 0.68 0.13 0.65 FALSE
3 GTEx Artery Tibial RPS6KL1 0.16 0.11 lasso 7 0.13 1.1e-10 5.4 5.4 7.3e-08 -0.71 0.19 0.81 FALSE
4 GTEx Esophagus Muscularis RPS6KL1 0.10 0.11 lasso 2 0.09 3.1e-06 5.4 5.2 1.6e-07 -0.72 0.28 0.71 FALSE
5 GTEx Nerve Tibial YLPM1 0.08 0.06 lasso 1 0.04 5.1e-04 5.4 5.4 7.2e-08 -0.76 0.06 0.80 FALSE
6 GTEx Nerve Tibial RPS6KL1 0.17 0.24 lasso 6 0.19 2.3e-13 5.0 5.2 1.7e-07 -0.76 0.58 0.42 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic RPS6KL1 0.08 0.08 enet 11 0.07 1.5e-04 5.8 6.1 1.1e-09 -0.94 0.03 0.97 FALSE
8 GTEx Testis AREL1 0.20 0.14 enet 34 0.13 2.1e-06 5.8 6.5 5.8e-11 -0.86 0.02 0.98 TRUE
9 GTEx Thyroid RPS6KL1 0.23 0.14 enet 14 0.14 1.3e-10 5.4 5.2 2.4e-07 -0.71 0.32 0.68 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma RPS6KL1 0.03 0.02 lasso 3 0.02 8.5e-06 5.9 6.0 2.5e-09 -0.86 0.01 0.99 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RPS6KL1 0.04 0.04 lasso 3 0.03 1.8e-04 5.8 5.8 7.5e-09 -0.88 0.01 0.98 FALSE
12 The Cancer Genome Atlas Lung Adenocarcinoma RPS6KL1 0.03 0.01 blup 49 0.02 2.3e-03 5.4 5.3 1.3e-07 -0.67 0.03 0.48 FALSE
13 The Cancer Genome Atlas Lung Squamous Cell Carcinoma RPS6KL1 0.02 0.02 lasso 2 0.02 5.6e-03 5.4 5.3 9.6e-08 -0.73 0.04 0.29 FALSE