Best TWAS P=5.24e-08 · Best GWAS P=3.93e-08 conditioned to 0.157
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | RANGAP1 | 0.07 | 0.02 | lasso | 4 | 0.02 | 0.00857 | 5.4 | -5.3 | 1.5e-07 | -0.93 | 0.02 | 0.93 | FALSE |
| 2 | GTEx | Nerve Tibial | ACO2 | 0.06 | 0.05 | lasso | 5 | 0.04 | 0.00085 | 4.1 | 5.1 | 2.7e-07 | 0.80 | 0.23 | 0.72 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | L3MBTL2 | 0.05 | 0.03 | enet | 9 | 0.04 | 0.00018 | 5.2 | 5.4 | 5.2e-08 | 0.89 | 0.01 | 0.97 | TRUE |