Best TWAS P=7.66e-08 · Best GWAS P=4.11e-08 conditioned to 0.216
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | MRAS | 0.52 | 0.53 | lasso | 5 | 0.54 | 2.5e-34 | 5.4 | 5.4 | 7.7e-08 | 0.95 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Artery Coronary | MRAS | 0.32 | 0.10 | lasso | 4 | 0.12 | 7.4e-05 | 5.3 | 5.3 | 1.3e-07 | 0.91 | 0.01 | 0.97 | FALSE |
| 3 | GTEx | Artery Tibial | MRAS | 0.24 | 0.20 | enet | 7 | 0.20 | 2.3e-15 | 5.4 | 5.1 | 2.7e-07 | 0.93 | 0.01 | 0.99 | FALSE |
| 4 | GTEx | Brain Frontal Cortex BA9 | DBR1 | 0.18 | 0.10 | lasso | 5 | 0.11 | 9.7e-04 | 5.3 | 5.4 | 7.8e-08 | 0.93 | 0.02 | 0.89 | FALSE |