[Hub]/) : Traits : Hypertension (Self-reported) :

chr3:157,125,828-159,106,064

Best TWAS P=2.95e-09 · Best GWAS P=7.49e-08 conditioned to 0.31

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta RP11-538P18.2 0.11 0.09 lasso 3 0.08 2.9e-05 4.6 -5.2 2.1e-07 -0.74 0.04 0.96 FALSE
2 GTEx Artery Tibial RP11-538P18.2 0.17 0.14 enet 24 0.21 3.7e-16 4.4 -5.9 2.9e-09 -0.80 0.14 0.85 TRUE
3 GTEx Brain Cerebellar Hemisphere RP11-538P18.2 0.17 0.11 lasso 4 0.04 4.1e-02 5.4 -5.6 2.7e-08 -0.95 0.02 0.78 FALSE
4 GTEx Cells Transformed fibroblasts RP11-538P18.2 0.10 0.08 enet 10 0.13 5.1e-10 4.4 -5.4 7.1e-08 -0.82 0.04 0.96 FALSE
5 GTEx Esophagus Muscularis RP11-538P18.2 0.11 0.16 lasso 5 0.15 1.2e-09 5.0 5.2 1.7e-07 0.83 0.04 0.96 FALSE
6 GTEx Lung RP11-379F4.7 0.05 0.01 lasso 3 0.01 1.2e-01 4.3 5.5 4.6e-08 0.76 0.07 0.55 FALSE
7 GTEx Ovary RP11-538P18.2 0.23 0.08 lasso 6 0.13 4.5e-04 4.4 -5.4 5.8e-08 -0.87 0.03 0.60 FALSE
8 GTEx Pancreas RP11-538P18.2 0.14 0.02 lasso 11 0.02 5.3e-02 4.9 -5.2 1.8e-07 -0.90 0.03 0.84 FALSE
9 GTEx Stomach RSRC1 0.08 0.06 lasso 3 0.07 2.9e-04 4.6 -5.1 2.9e-07 -0.89 0.02 0.96 FALSE
10 GTEx Vagina RP11-538P18.2 0.25 0.19 lasso 3 0.18 6.7e-05 5.4 -5.5 3.1e-08 -0.99 0.01 0.92 FALSE
11 METSIM Adipose RSRC1 0.14 0.19 blup 532 0.21 6.0e-31 4.4 -5.8 6.6e-09 -0.59 0.28 0.68 FALSE