Hub : Genes

RSRC1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0400 0.0210 6.9e-03 0.007 0.006 -0.001 0.006 0.001 4.5e-02 6.1e-02 4.9e-01 4.8e-02 2.3e-01
2 GTEx Adipose Subcutaneous 0.1510 0.0390 6.9e-10 0.167 NA 0.160 NA 0.181 1.4e-13 NA 5.1e-13 NA 9.7e-15
3 GTEx Adipose Visceral Omentum 0.1630 0.0550 9.0e-06 0.075 NA 0.088 NA 0.082 1.0e-04 NA 2.5e-05 NA 5.0e-05
4 GTEx Artery Aorta 0.0920 0.0400 2.0e-03 0.036 NA 0.025 NA 0.026 4.6e-03 NA 1.4e-02 NA 1.4e-02
5 GTEx Artery Tibial 0.1331 0.0439 3.5e-07 0.134 NA 0.093 NA 0.113 1.1e-10 NA 9.1e-08 NA 3.5e-09
6 GTEx Brain Cortex 0.4290 0.1450 3.0e-03 0.022 NA -0.010 NA 0.005 8.0e-02 NA 7.4e-01 NA 2.3e-01
7 GTEx Brain Nucleus accumbens basal ganglia 0.5000 0.1190 1.1e-03 -0.011 NA 0.055 NA -0.004 8.2e-01 NA 1.4e-02 NA 4.4e-01
8 GTEx Breast Mammary Tissue 0.1440 0.0520 1.8e-05 0.105 NA 0.115 NA 0.127 4.7e-06 NA 1.6e-06 NA 4.9e-07
9 GTEx Breast Mammary Tissue (Male) 0.2356 0.1153 1.3e-02 0.105 NA 0.149 NA 0.191 2.0e-03 NA 2.6e-04 NA 3.4e-05
10 GTEx Breast Mammary Tissue (Female) 0.2388 0.0897 3.0e-04 0.051 NA 0.126 NA 0.077 1.2e-02 NA 1.4e-04 NA 2.7e-03
11 GTEx Esophagus Mucosa 0.0910 0.0380 1.1e-03 0.017 NA 0.041 NA 0.006 2.3e-02 NA 9.3e-04 NA 1.3e-01
12 GTEx Esophagus Muscularis 0.0610 0.0280 3.7e-03 0.090 NA 0.061 NA 0.097 4.2e-06 NA 1.5e-04 NA 1.7e-06
13 GTEx Lung 0.0898 0.0330 1.3e-04 0.054 NA 0.057 NA 0.049 5.2e-05 NA 3.5e-05 NA 1.3e-04
14 GTEx Muscle Skeletal 0.1068 0.0447 1.8e-04 0.061 NA 0.013 NA 0.037 1.2e-06 NA 1.6e-02 NA 1.5e-04
15 GTEx Nerve Tibial 0.1036 0.0361 3.4e-06 0.150 NA 0.073 NA 0.119 8.4e-11 NA 6.8e-06 NA 9.9e-09
16 GTEx Skin Not Sun Exposed Suprapubic 0.0740 0.0340 2.4e-03 0.093 NA 0.027 NA 0.059 8.4e-06 NA 1.3e-02 NA 3.7e-04
17 GTEx Skin Sun Exposed Lower leg 0.0850 0.0310 1.0e-04 0.093 NA 0.054 NA 0.079 3.9e-08 NA 2.8e-05 NA 4.4e-07
18 GTEx Stomach 0.0790 0.0350 1.8e-03 0.059 NA 0.057 NA 0.070 8.4e-04 NA 1.1e-03 NA 2.9e-04
19 GTEx Thyroid 0.0750 0.0290 3.5e-04 0.041 NA 0.009 NA 0.021 4.1e-04 NA 5.7e-02 NA 8.5e-03
20 METSIM Adipose 0.1445 0.0305 0.0e+00 0.188 0.211 0.201 0.211 0.196 2.0e-27 6.0e-31 2.3e-29 7.2e-31 1.3e-28
21 YFS Blood 0.1338 0.0262 0.0e+00 0.129 0.164 0.172 0.169 0.164 5.7e-40 2.8e-51 8.8e-54 9.1e-53 4.3e-51
22 TCGA Breast Invasive Carcinoma 0.0415 0.0233 1.9e-07 0.029 0.035 0.042 NA 0.036 8.9e-07 9.0e-08 4.5e-09 NA 6.1e-08
23 TCGA Brain Lower Grade Glioma 0.0499 0.0373 1.7e-03 0.026 0.014 0.014 NA 0.013 5.8e-04 7.9e-03 8.5e-03 NA 1.2e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bipolar Disorder (2018) 3.7 5.9 12.4 2.6 2.1 2.7 2.0 2.2 2.7 0.2 2.3 1.8 2.3 2.6 -2.3 3.5 2.2 2.2 2.1 2.3 2.5 2.0 3.0 3.1 2.8 2.8
Bipolar Disorder or Schizophrenia 2.0 4.9 10.1 1.6 2.0 2.9 2.4 2.0 1.5 1.3 2.3 1.2 1.7 2.1 -2.7 3.2 1.9 2.0 1.9 2.0 2.9 2.2 2.4 2.3 2.8 2.5
Depressed Affect (Nagel 2018) 0.6 1.2 10.2 0.7 -0.2 -0.6 -0.8 0.1 3.1 -3.2 0.1 -0.1 0.7 -0.7 0.7 0.8 0.2 0.2 -0.3 0.6 -0.2 -0.9 0.2 1.9 0.3 0.3
Depression (Nagel 2018) 1.9 2.9 8.6 0.7 2.1 1.1 0.2 2.2 2.5 -1.4 1.9 2.0 0.3 0.3 -0.5 2.3 2.3 2.3 1.8 2.4 1.1 0.3 0.9 2.9 1.3 1.3
Intelligence (Savage-Jansen 2018) 0.1 0.4 1.3 -0.7 -0.7 -0.2 -0.5 -0.6 -0.3 -0.9 -1.1 -0.9 -0.6 -0.5 0.1 -0.6 -0.5 -0.6 -0.5 -0.6 -0.7 -0.3 0.1 -0.6 -0.8 -1.2
Neuroticism (Nagel 2018) 1.2 2.8 22.6 0.2 -1.6 -1.5 -1.6 -1.1 3.2 -4.8 -1.4 -1.0 -1.3 -1.5 1.4 -0.4 -1.0 -1.0 -1.5 -0.4 -1.2 -1.7 -1.6 1.2 -0.5 -0.5
Schizophrenia (2018) 0.5 1.0 2.8 -0.0 0.9 1.6 1.5 0.8 -0.2 1.5 1.1 0.1 0.4 0.6 -1.6 1.2 0.6 0.8 0.8 0.7 1.7 1.3 0.7 0.4 1.3 0.9
Schizophrenia vs Biploar Disorder 1.9 2.5 5.5 -2.2 -1.0 -1.4 -0.9 -1.5 -2.3 0.2 -1.2 -1.1 -1.6 -2.1 1.4 -1.6 -1.5 -1.5 -1.5 -1.6 -1.2 -1.2 -1.9 -2.0 -1.9 -1.9
Worry (Nagel 2018) 3.0 6.3 17.0 -0.4 -3.1 -2.5 -3.0 -2.5 1.5 -4.1 -3.2 -1.9 -3.3 -2.5 2.4 -1.9 -2.3 -2.3 -2.5 -1.7 -2.6 -2.4 -3.5 -0.6 -1.6 -2.2
Alzheimer’s Disease (in mother) 0.7 0.8 3.0 -1.7 -0.4 -0.9 -0.1 -0.6 -1.6 0.0 -0.4 -0.4 -0.7 0.4 1.0 -0.7 -0.6 -0.8 -0.6 -0.9 -0.8 -0.6 -1.2 -1.5 -0.9 -0.7
Alzheimer’s Disease (in father) 1.3 1.4 4.3 -0.2 -1.7 -1.2 -0.7 -1.5 0.7 -2.1 -1.5 -0.8 -0.8 -0.0 1.3 -1.5 -1.4 -1.4 -1.2 -1.1 -1.4 -1.0 -1.1 -0.1 -1.3 -0.9
Alzheimer’s Disease (including proxy) 1.1 1.7 3.1 -1.6 -1.4 -1.4 -0.7 -1.4 -0.7 -1.1 -1.2 -0.7 -1.4 0.4 1.8 -1.2 -1.2 -1.5 -1.2 -1.3 -1.5 -1.1 -1.6 -1.4 -1.6 -1.2
Crohns Disease (2017) 0.8 1.9 5.0 -1.5 -1.2 -1.7 -1.3 -1.5 -1.2 -0.1 -1.0 -0.9 -1.2 -1.1 1.5 -0.6 -1.4 -1.3 -1.2 -1.4 -1.4 -1.5 -2.2 -1.2 -2.2 -1.3
Irritable Bowel Disease (IBD) 1.9 4.4 10.0 -1.3 -2.1 -2.8 -2.9 -2.2 -0.7 0.7 -1.8 -2.0 -0.7 -2.8 3.2 -0.9 -2.0 -1.9 -1.8 -2.0 -2.2 -2.3 -2.6 -1.5 -3.1 -1.6
Ulcerative Colitis (UC) 1.4 2.6 9.1 -0.4 -1.5 -2.2 -3.0 -1.4 0.3 0.9 -1.3 -1.7 0.0 -2.4 3.0 -0.4 -1.1 -1.1 -1.0 -1.2 -1.8 -2.1 -1.2 -0.8 -2.2 -1.2
Major Depression (MDD) 1.9 2.3 5.2 -0.4 1.2 1.9 1.2 1.7 2.0 -1.7 1.3 1.6 0.4 2.3 -1.5 1.6 1.6 1.5 1.4 1.6 1.3 1.9 1.2 1.3 1.2 1.4
Reaction Time 0.2 0.4 1.5 0.5 0.6 0.5 0.3 0.6 0.4 0.6 0.4 0.8 -0.5 0.7 -0.3 1.0 0.6 0.6 0.3 0.7 0.5 -0.2 0.8 0.9 1.2 0.7
Verbal and Numeric Reasoning (VNR) 0.1 0.4 1.0 0.2 -0.9 -0.2 0.0 -0.9 0.8 -1.0 -1.0 0.1 -0.5 0.4 -0.2 -0.4 -0.8 -0.9 -0.7 -0.6 -0.5 -0.5 0.3 -0.1 -0.3 -0.6
Breast Cancer 0.9 2.3 13.2 0.6 -0.2 -1.9 -1.5 -1.2 -0.2 3.6 -0.2 -0.8 -0.1 -1.3 2.6 -0.2 -0.7 -0.9 -0.7 -0.6 -2.5 -3.0 -0.5 -0.4 -1.6 -1.2
Ovarian Cancer 0.3 0.4 1.9 -1.2 0.3 -0.1 -0.5 -0.5 0.7 -0.1 -0.2 -0.4 -1.4 0.2 0.7 0.5 -0.2 -0.5 -0.5 -0.2 -1.3 -0.8 -0.7 0.6 -0.9 -0.1
Prostate Cancer 0.3 0.4 6.3 -0.8 -0.3 -0.0 0.1 -0.1 0.1 -2.5 -0.5 0.1 -0.9 0.1 -0.3 -1.0 -0.0 -0.1 0.1 0.0 -0.6 -0.4 -0.3 -0.1 -0.0 -0.5
Age at First Birth 0.5 0.8 4.4 -0.1 -1.2 0.0 0.5 -1.1 0.1 0.0 -1.2 -0.2 -2.1 0.3 0.3 -0.5 -1.1 -1.1 -1.2 -1.3 -0.8 -0.2 -1.0 -0.9 -0.5 0.4
Bipolar Disorder (2011) 1.3 1.3 2.5 0.6 1.3 1.2 1.0 1.5 0.7 0.6 1.2 0.6 1.2 0.9 -1.0 1.3 1.3 1.3 1.4 1.2 1.4 1.6 1.1 0.9 0.9 1.3
Body Mass Index (BMI) (2010) 3.8 5.2 9.6 -2.3 -2.0 -2.3 -1.7 -2.6 -2.1 0.3 -2.1 -2.1 -3.1 -1.0 2.6 -1.7 -2.4 -2.5 -2.5 -2.6 -2.7 -2.2 -2.3 -2.2 -3.0 -2.2
Coronary Artery Disease (CAD) 0.4 0.5 2.0 1.4 -0.2 1.0 1.0 -0.1 0.5 1.1 -0.1 0.1 1.2 1.3 -1.1 -0.3 -0.3 -0.0 -0.0 -0.2 0.6 0.4 0.1 -0.1 0.7 0.7
Crohns Disease (2012) 0.7 1.1 3.7 -1.1 -0.9 -0.7 0.2 -1.2 -1.9 -0.6 -0.8 -0.6 -0.6 -0.3 0.0 -1.3 -1.3 -1.1 -1.1 -1.3 -0.5 -0.2 -1.8 -1.3 -1.3 -0.9
Mean Putamen Volume 6.2 7.0 13.3 2.7 3.0 2.4 1.2 2.9 3.6 1.8 3.3 2.7 1.2 2.5 -1.5 3.1 3.0 2.9 2.9 3.0 2.0 1.3 3.2 3.4 2.5 2.7
Fasting Glucose 0.3 0.4 1.7 -0.3 -0.6 -0.3 -0.4 -0.4 -0.7 1.3 -0.0 -0.3 0.4 0.5 0.2 -0.8 -0.5 -0.5 -0.4 -0.6 0.3 0.8 -0.5 -1.2 -0.5 -0.3
HbA1C 0.3 0.3 0.9 -0.1 0.7 0.2 0.1 0.8 0.7 -0.8 0.8 0.4 0.4 0.7 0.1 -0.7 0.9 0.7 0.8 0.9 -0.2 0.2 0.3 -0.0 -0.0 0.2
HDL Cholesterol 0.7 1.1 3.0 1.0 1.3 0.6 0.1 1.6 -0.0 0.2 1.1 1.7 -0.0 0.5 -0.7 0.2 1.5 1.6 1.4 1.6 1.0 0.7 1.4 0.6 1.5 0.6
LDL Cholesterol 0.6 0.9 2.3 -0.8 -0.7 -1.2 -1.3 -0.9 -0.1 -0.9 -0.7 -1.1 0.8 -1.3 1.1 -0.3 -0.8 -0.9 -0.9 -0.7 -1.2 -1.0 -0.3 -0.0 -1.2 -1.5
Lupus 0.3 0.4 2.4 -0.3 0.5 0.6 0.4 0.3 1.6 1.5 0.7 0.6 0.2 -0.2 -0.4 0.9 0.4 0.4 0.3 0.5 0.2 0.7 -0.5 0.4 0.3 0.6
Neuroticism (2016) 1.0 1.4 5.7 0.9 1.3 0.7 -0.3 1.5 2.4 -0.6 1.2 0.9 0.2 0.3 -0.2 1.7 1.6 1.6 1.3 1.8 0.3 -0.2 0.9 1.9 0.9 1.0
Primary Biliary Cirrhosis 0.4 0.5 1.4 -0.7 -0.7 -0.6 -0.5 -0.9 1.2 0.1 -0.9 0.0 -0.4 -0.6 0.5 0.4 -0.7 -0.9 -1.0 -0.6 -1.1 -0.8 -0.5 0.4 -1.1 -0.6
Rheumatoid Arthritis 1.0 1.4 5.1 -0.5 1.2 0.9 1.3 1.4 -0.6 -0.5 0.9 2.3 -0.8 1.1 -1.7 1.1 1.3 1.4 1.1 1.3 1.1 1.1 1.1 0.6 1.5 0.6
Schizophrenia (2014) 0.3 0.7 2.0 -0.4 0.9 1.1 1.3 0.7 -0.7 0.5 1.2 0.2 0.8 0.8 -1.4 1.0 0.7 0.8 0.8 0.7 1.1 0.7 0.5 0.1 0.9 0.3
Triglycerides 0.4 0.7 2.3 -1.1 -0.3 -1.3 -1.5 -0.3 0.6 -0.7 -0.4 -0.7 -0.4 -0.6 1.2 0.3 -0.1 -0.3 -0.2 -0.2 -1.3 -1.3 -0.6 0.6 -1.5 -1.3
Type 2 Diabetes (T2D) (2012) 2.3 2.6 5.9 -1.7 -2.2 -1.0 -0.2 -2.3 -1.7 0.1 -1.9 -1.1 -0.5 -0.1 1.1 -1.2 -2.4 -2.4 -2.4 -2.3 -1.5 -0.8 -1.7 -1.7 -1.7 -1.5
Ulcerative Colitis 0.8 1.1 3.8 0.2 -1.1 -1.2 -2.0 -1.1 -0.2 1.8 -0.8 -1.2 -0.6 -1.2 1.9 -0.2 -0.8 -0.8 -0.5 -0.9 -1.0 -1.1 -1.1 -0.4 -1.0 -0.4
Blood Eosinophil Count 0.1 0.7 3.1 -1.0 0.2 -1.3 -1.5 -0.4 0.3 1.2 0.2 0.2 0.1 -0.3 1.8 0.1 -0.1 -0.2 -0.4 -0.1 -1.3 -1.4 -0.1 0.0 -1.5 -0.9
Blood Platelet Count 0.1 1.4 4.2 1.0 1.0 -0.3 -0.3 0.9 0.4 2.1 1.3 0.9 1.7 0.4 -0.1 1.9 1.1 1.3 1.1 1.4 0.5 -0.6 1.6 1.7 1.7 0.4
Blood Red Count 0.1 1.0 3.6 -1.2 -0.9 -0.5 0.7 -1.2 -1.9 -0.3 -0.5 0.2 -1.2 0.0 0.2 -0.5 -1.3 -1.3 -1.1 -1.7 -0.5 -0.0 -1.0 -1.5 -0.9 -0.4
Blood White Count 0.7 4.9 10.0 2.7 2.3 1.8 2.1 1.9 1.9 2.6 2.5 2.6 2.2 1.1 -1.5 2.0 2.0 2.1 2.0 2.1 1.9 1.3 3.2 2.7 2.2 2.7
Heel T-Score 0.7 5.3 13.7 -0.1 -3.1 -1.6 -0.6 -3.7 1.1 0.4 -2.5 -2.5 -1.3 -2.2 1.0 -1.9 -3.5 -3.2 -3.5 -3.2 -1.7 -1.4 -3.0 -2.2 -2.3 -1.5
BMI 3.1 18.2 35.2 -2.7 -3.6 -5.3 -4.1 -4.1 -5.9 0.6 -3.9 -3.3 -5.5 -3.5 4.4 -4.2 -3.7 -3.9 -3.5 -4.2 -5.2 -4.9 -3.6 -5.3 -4.2 -5.4
Height 2.7 51.7 125.4 4.7 4.8 9.3 10.0 5.9 8.0 -0.4 6.3 5.9 8.4 8.0 -9.7 5.9 4.7 5.3 4.9 5.2 9.6 11.2 4.7 5.5 7.8 9.7
Waist Hip Ratio (WHR) 1.6 7.3 15.9 2.4 3.2 2.4 1.6 2.9 4.0 0.9 3.2 3.0 2.2 1.3 -1.8 2.3 2.9 3.0 2.5 3.4 2.6 2.2 2.0 3.6 2.4 3.7
Systolic Blood Pressure 5.2 26.1 38.9 -3.6 -5.8 -6.1 -5.2 -5.4 -3.2 -3.2 -6.2 -4.1 -5.0 -5.3 4.9 -5.1 -5.1 -5.2 -5.1 -5.0 -5.6 -5.6 -5.5 -4.9 -5.0 -6.0
Smoking Status 1.0 2.5 10.4 1.4 1.6 0.4 -0.8 1.8 2.1 -0.0 1.8 1.5 2.1 0.3 -0.3 1.6 2.0 2.0 1.4 2.3 0.9 0.2 3.2 2.0 0.9 0.5
Allergy or Eczema 0.4 1.0 1.9 -0.1 -1.0 -0.8 -0.6 -1.0 -1.0 0.3 -1.3 -1.2 -1.4 -1.2 0.5 -1.2 -1.0 -1.1 -0.9 -1.0 -0.9 -0.5 -1.1 -1.4 -0.7 -1.4
Cardiovascular Disease 3.8 12.7 20.3 -2.9 -3.7 -4.2 -3.5 -4.0 -2.1 0.0 -3.9 -2.9 -3.1 -3.6 4.2 -3.0 -3.5 -3.6 -3.7 -3.4 -4.3 -4.3 -4.5 -2.9 -3.9 -3.9
Hypothyroidism (self reported) 1.3 3.0 10.2 -3.2 -1.6 -1.3 0.6 -1.9 -2.2 -0.5 -1.6 -0.8 -1.0 -1.2 0.5 -2.0 -1.9 -1.9 -2.1 -2.1 -1.6 -0.9 -1.4 -2.4 -2.1 -1.9
Respiratory disease 1.0 2.2 7.7 0.1 -0.4 -2.2 -2.6 -0.6 -0.8 0.2 -0.7 -1.5 -1.5 -2.0 2.4 -1.8 -0.3 -0.4 -0.3 -0.4 -2.3 -2.8 -0.4 -0.6 -1.3 -2.1
Type 2 Diabetes (T2D) (2018) 1.8 3.3 6.2 -1.9 -2.0 -1.8 -1.6 -2.4 -0.5 -1.4 -2.1 -2.1 -1.8 -1.0 2.5 -0.8 -2.1 -2.2 -2.4 -2.0 -1.9 -1.9 -1.1 -1.1 -2.0 -1.7
Lung FEV1/FVC ratio 1.5 7.9 15.3 -2.7 -2.5 -3.4 -3.4 -2.7 -2.5 -0.5 -2.5 -2.0 -2.9 -2.5 3.9 -2.0 -2.5 -2.8 -2.6 -2.7 -3.5 -3.1 -3.0 -2.8 -3.2 -2.9
Lung FVC 19.1 97.3 131.1 9.5 10.8 10.4 8.7 11.1 6.7 4.9 10.1 10.0 5.5 8.4 -10.3 10.3 10.7 10.9 10.7 10.8 11.3 8.9 11.5 11.0 10.7 9.9
Neuroticism 1.2 2.8 21.5 0.5 -1.6 -1.7 -2.2 -1.0 2.8 -4.6 -1.5 -1.3 -1.6 -0.8 1.5 -0.1 -0.8 -0.7 -1.2 -0.1 -1.2 -1.9 -1.6 1.6 -0.3 -0.7
Chronotype (morning person) 0.5 1.1 5.5 1.6 0.3 0.1 -0.9 1.1 2.3 -1.1 0.6 1.1 1.0 -0.6 -0.3 0.7 1.0 1.1 1.0 1.5 0.7 0.7 -0.1 1.4 0.8 0.7
Hair Pigment 0.0 1.0 3.4 -0.1 1.8 0.0 -0.1 1.1 0.8 0.2 1.8 1.6 1.3 -0.7 0.6 1.4 1.3 1.3 1.1 1.0 -0.0 -0.4 0.7 0.7 -0.4 0.6
Tanning 0.0 0.4 2.7 0.4 0.8 -0.2 -0.5 0.5 -0.6 0.7 -0.1 -0.3 -1.6 0.5 0.5 0.2 0.6 0.3 0.3 0.3 -0.8 -0.9 1.5 0.0 -0.2 -0.6
Hand grip strength (left) 3.3 8.8 15.2 3.7 2.6 3.6 3.2 2.3 2.9 1.7 2.9 2.3 2.9 3.1 -3.5 3.0 2.2 2.4 2.4 2.4 3.2 3.3 2.6 2.9 3.7 3.9
Number of treatments/medications taken 0.5 1.0 3.3 -1.0 0.9 -1.2 -1.5 0.7 -0.4 1.0 0.7 0.4 -0.3 -1.8 1.8 0.5 1.0 0.9 0.6 0.9 -0.9 -1.6 -0.2 -0.1 -0.9 -0.8
Average weekly spirits intake 1.1 1.4 5.2 -2.3 -0.1 -1.0 -1.7 -0.5 -2.2 1.1 -0.5 -1.2 -1.1 -0.1 1.5 -0.3 -0.5 -0.8 -0.7 -0.9 -1.4 -1.1 -1.2 -1.8 -0.8 -1.3
Sensitivity / hurt feelings 0.2 0.4 3.4 -0.6 -0.4 -0.7 -0.7 -0.2 1.8 -1.3 -0.2 -0.2 0.2 -0.3 0.7 0.6 -0.1 -0.1 -0.2 0.1 -0.3 -0.4 -0.7 0.9 -0.3 0.1
Frequency of depressed mood in last 2 weeks 1.5 2.0 5.7 0.5 1.7 0.9 0.3 1.9 2.0 -1.6 1.6 0.9 0.9 -0.1 -0.4 1.6 1.9 1.9 1.7 2.0 1.4 1.0 0.5 2.4 0.8 1.6
Hearing difficulty/problems: Yes 0.2 0.3 3.9 -0.6 0.3 -0.2 -0.7 0.3 0.4 -2.0 -0.1 -0.5 -0.8 0.5 0.4 -0.0 0.4 0.4 0.0 0.5 -0.6 -0.5 -0.5 0.1 0.3 -0.3
Relative age of first facial hair 0.1 0.1 0.6 -0.3 0.2 -0.5 -0.3 -0.3 0.6 0.8 0.2 0.2 -0.0 -0.0 0.7 0.5 -0.1 -0.0 -0.2 -0.2 -0.5 -0.6 -0.1 0.5 -0.2 0.1
Other serious medical condition/disability diagnosed by doctor 0.3 0.4 1.5 -1.2 -0.5 0.1 0.3 -0.3 -0.9 -1.2 -0.6 -1.1 -0.1 -0.2 -0.5 -0.9 -0.4 -0.4 -0.3 -0.4 -0.1 0.2 -0.4 -0.6 -0.0 -0.9
Ever used hormone-replacement therapy (HRT) 0.3 0.4 2.4 0.5 0.9 0.1 0.2 0.6 0.3 -0.9 0.7 1.5 -0.4 0.6 -0.0 -0.5 0.6 0.6 0.4 0.7 0.1 0.1 0.4 1.0 0.0 -0.1
Ever had hysterectomy (womb removed) 0.4 0.4 1.7 -0.4 -0.7 -0.3 -0.2 -1.0 -0.7 -0.2 -0.6 -1.3 -0.5 0.7 0.5 -0.1 -0.9 -1.0 -0.9 -1.0 -0.4 -0.4 0.2 -0.5 -0.5 -0.4
Systolic blood pressure, automated reading 6.8 19.7 29.5 -3.3 -5.0 -4.7 -3.5 -4.7 -4.7 -2.1 -5.4 -3.0 -5.0 -4.6 3.6 -4.9 -4.6 -4.7 -4.4 -4.7 -4.3 -3.9 -5.1 -5.4 -4.0 -4.8
Eye problems/disorders: Diabetes related eye disease 1.5 1.6 4.6 -0.5 -1.3 -1.6 -1.0 -1.5 -0.4 -0.6 -1.4 -0.6 -0.9 -1.1 2.1 -1.5 -1.5 -1.4 -1.6 -1.4 -1.5 -1.3 -1.2 -0.9 -1.4 -0.9
Angina 1.7 2.3 12.2 -0.3 -1.6 -1.2 -2.4 -1.4 -0.9 -1.2 -1.9 -3.5 -0.3 -1.5 1.5 -0.7 -1.4 -1.5 -1.4 -1.5 -1.2 -1.0 -1.2 -0.7 -1.2 -1.5
Medication for hormone replacement therapy 0.7 0.8 2.9 -1.7 -1.0 -0.5 -0.1 -0.8 -0.1 -1.4 -0.9 -0.4 -0.2 -0.4 0.1 -1.7 -0.9 -1.0 -0.9 -0.9 -0.3 0.4 -1.0 -1.0 -1.1 -0.7
Vitamin and mineral supplements 0.4 0.5 2.3 -0.4 0.5 0.4 0.6 0.5 1.5 0.7 0.5 0.6 1.4 -0.3 -0.1 0.9 0.4 0.5 0.3 0.4 0.7 0.8 0.0 0.6 -0.0 1.2
Supplements: Zinc 0.7 0.8 5.5 0.1 0.4 1.0 1.2 0.4 -0.2 -0.9 0.4 1.5 -0.3 2.3 -1.4 0.4 0.3 0.4 0.2 0.4 0.8 0.8 0.8 0.6 1.4 0.2
Medication: Co-codamol 0.3 0.3 1.7 -0.8 -0.1 -0.9 -0.7 0.1 0.3 -0.7 0.0 -0.4 -0.1 -0.7 1.3 -0.1 0.1 0.0 -0.2 -0.0 -0.5 -0.3 -0.8 -0.2 -0.9 0.0
Medication: Metformin 2.3 3.2 7.9 -1.4 -2.0 -1.8 -1.7 -2.2 -1.0 -0.3 -1.9 -1.9 -1.8 -0.0 2.8 -0.9 -2.0 -2.1 -2.2 -2.0 -2.1 -2.2 -0.6 -1.7 -1.7 -1.9
Diabetes (father) 0.6 0.7 4.3 -0.7 0.4 1.3 1.2 0.5 0.5 0.7 0.6 0.4 0.8 1.0 -0.7 0.8 0.3 0.3 0.4 0.2 1.0 2.1 0.3 0.1 0.3 1.5
Diabetes (mother) 1.3 1.7 3.9 -0.7 -1.0 -1.3 -1.0 -1.2 -1.5 1.5 -1.2 -1.2 -0.1 -1.7 0.9 -1.5 -1.2 -1.2 -1.1 -1.3 -1.3 -1.2 -1.3 -1.6 -2.0 -1.5
Severe depression (siblings) 0.9 1.1 5.2 1.4 0.8 0.1 -0.9 0.8 1.4 2.3 0.8 0.2 0.1 -0.5 0.4 1.9 1.0 1.1 1.1 1.2 0.1 -0.4 0.5 1.7 0.1 0.5
Pack years adult smoking proportion 2.0 3.1 5.4 1.0 1.9 2.3 1.9 2.0 1.2 0.3 1.9 2.3 1.0 1.8 -1.8 1.5 1.9 1.9 2.0 1.9 1.6 2.0 1.9 1.8 1.5 1.8
Impedance of leg (right) 0.7 3.2 12.2 -1.8 1.1 2.9 3.4 1.1 0.3 -2.4 1.0 1.6 0.7 1.5 -2.7 1.3 0.8 0.8 0.6 0.7 2.4 3.5 1.4 1.2 0.4 1.9
Leg fat-free mass (left) 0.1 0.4 3.8 1.1 -0.3 -0.7 0.2 -0.4 0.4 1.9 0.2 -0.0 1.3 0.2 -0.0 0.1 -0.4 -0.2 -0.3 -0.2 -0.2 -0.4 -0.6 -0.7 0.6 0.2
Trunk fat percentage 0.9 3.6 15.7 -1.7 -1.4 -2.0 -1.1 -1.7 -4.0 0.8 -1.5 -1.2 -2.7 -1.2 1.3 -2.2 -1.6 -1.7 -1.4 -1.9 -1.9 -1.4 -1.0 -2.9 -1.7 -2.6
Hand grip strength (right) 3.7 10.1 20.7 3.6 2.3 3.8 4.1 2.2 3.6 1.2 2.7 2.6 3.3 3.0 -4.2 3.1 2.1 2.3 2.3 2.3 3.9 3.8 3.0 3.0 3.7 4.5
Townsend deprivation index at recruitment 0.7 1.0 3.3 -0.6 -0.7 -1.3 -1.6 -0.6 -0.2 -1.8 -1.0 -1.7 -0.8 -1.8 0.7 -0.9 -0.7 -0.6 -0.5 -0.7 -0.5 -0.5 -0.8 -0.3 -1.1 -1.2
Current tobacco smoking 0.9 1.4 3.5 0.5 1.5 0.1 -0.8 1.7 1.6 -1.0 1.1 1.7 0.9 -0.3 0.2 0.6 1.8 1.7 1.4 1.9 0.2 -0.1 1.7 1.6 -0.0 0.1
Average weekly fortified wine intake 0.2 0.3 1.0 -0.7 -0.3 -0.4 -0.4 -0.4 -0.1 -0.3 -0.3 -0.6 0.4 -0.8 0.5 -0.5 -0.3 -0.5 -0.3 -0.4 -1.0 -0.4 -0.6 -0.8 -0.5 -0.3
Maternal smoking around birth 2.4 3.5 12.0 1.1 2.5 0.9 0.4 2.3 1.5 0.2 2.7 1.3 3.5 1.1 -0.6 2.3 2.4 2.4 2.2 2.5 1.3 0.7 1.9 2.2 1.5 1.4
Fed-up feelings 0.8 1.5 9.7 0.5 1.1 -0.2 -0.5 1.1 3.1 -2.3 1.2 0.6 2.1 -1.1 0.5 0.4 1.1 1.1 0.6 1.4 0.6 -0.1 0.7 1.7 0.2 0.8
Frequency of unenthusiasm / disinterest in last 2 weeks 1.6 2.2 6.7 0.4 2.1 0.6 -0.3 1.9 2.4 -0.7 2.0 1.6 0.8 -0.8 -0.0 1.8 2.0 2.0 1.7 2.2 0.9 0.1 0.7 2.6 0.4 0.7
Relative age voice broke 1.2 1.9 4.3 0.5 0.8 1.8 1.5 1.0 1.9 -0.3 0.9 1.0 1.0 1.9 -1.2 1.9 0.8 0.9 0.7 0.7 2.0 2.1 0.9 1.8 1.4 2.0
Taking other prescription medications 0.3 0.4 1.3 -0.7 0.4 -0.8 -0.6 0.2 0.5 1.1 0.4 0.6 -0.6 -1.0 1.0 -0.0 0.4 0.3 0.3 0.4 -0.9 -1.1 -0.7 0.0 -0.5 -0.3
Age when periods started (menarche) 0.1 0.3 2.3 1.5 0.2 -0.0 0.2 0.3 0.1 0.2 0.1 0.2 0.8 -1.4 -0.5 0.0 0.2 0.3 0.4 0.4 0.3 0.0 0.3 0.4 -0.1 0.0
Bilateral oophorectomy (both ovaries removed) 1.0 1.2 3.0 0.4 -1.1 -0.7 -1.2 -1.2 -1.1 0.7 -1.4 -1.3 -1.7 -1.2 1.3 -0.6 -1.2 -1.4 -1.1 -1.3 -1.1 -0.9 -1.0 -0.3 -1.1 -0.9
Heel bone mineral density (BMD) T-score, automated (left) 0.4 1.0 4.5 0.9 -1.1 -1.1 -0.2 -1.5 0.5 -0.0 -1.1 -0.0 -2.1 -1.3 0.6 -0.5 -1.3 -1.2 -1.1 -1.1 -0.8 -0.7 -0.8 -0.8 -0.8 -0.3
Tinnitus: Yes, but not now, but have in the past 1.0 1.1 3.0 -1.4 -0.6 -1.4 -1.2 -0.6 -0.9 -0.9 -0.8 -0.6 -1.0 -1.4 1.2 -0.3 -0.3 -0.5 -0.5 -0.5 -1.7 -1.7 -0.4 -0.9 -1.1 -1.7
Qualifications: CSEs or equivalent 2.1 2.8 6.3 -1.8 -1.3 -2.0 -1.9 -1.3 -0.5 -1.3 -1.5 -1.5 -1.9 -1.8 2.4 -1.2 -1.1 -1.3 -1.3 -1.2 -2.2 -2.2 -1.9 -1.2 -2.5 -1.5
Serious illness, injury or assault to yourself 0.5 0.6 1.5 0.8 1.1 -0.6 -0.2 1.0 0.6 -0.9 0.6 1.0 0.1 -1.0 -0.3 0.1 1.1 1.2 1.0 1.2 0.6 -0.2 0.8 0.9 0.6 0.1
High blood pressure 6.4 17.8 30.1 -3.4 -4.4 -4.7 -3.8 -4.9 -3.0 0.2 -4.5 -3.0 -4.0 -3.6 4.8 -4.1 -4.5 -4.3 -4.6 -4.4 -4.9 -4.6 -5.5 -4.5 -4.5 -4.2
Hayfever, allergic rhinitis or eczema 0.4 0.8 1.5 -0.1 -1.1 -0.6 -0.3 -1.1 -0.6 -0.6 -1.2 -1.2 -1.0 -1.2 0.5 -1.1 -1.1 -1.2 -1.2 -1.0 -0.6 -0.4 -0.7 -1.1 -0.5 -1.0
Multivitamins +/- minerals 0.2 0.3 1.4 0.3 -0.2 -0.4 -0.5 -0.3 -1.2 -0.2 -0.3 -0.4 -0.4 -0.3 0.3 -1.0 -0.2 -0.4 -0.1 -0.3 -0.9 -0.7 0.2 -0.4 -0.2 -1.0
Stomach or abdominal pain in last month 4.0 5.0 11.6 -1.5 -2.1 -3.4 -2.9 -2.2 -0.6 -0.7 -2.1 -1.8 -1.7 -1.6 3.0 -2.2 -1.8 -1.8 -2.0 -1.6 -3.1 -3.4 -2.2 -0.7 -2.5 -2.8
Supplements: Glucosamine 0.3 0.3 1.2 0.3 1.0 0.2 0.1 0.7 -0.8 1.1 0.5 0.6 -0.3 -0.4 0.0 0.4 0.8 0.6 0.7 0.5 -0.6 -0.5 0.7 0.1 0.8 0.0
Diverticular disease/diverticulitis (self-reported) 0.3 0.4 1.7 0.3 -0.2 -0.9 -0.3 -0.6 -0.6 0.0 0.0 -0.3 0.2 -0.6 0.5 -1.3 -0.5 -0.6 -0.5 -0.5 -1.1 -0.9 -0.5 -0.6 -0.6 -0.8
Medication: Atenolol 0.7 0.9 4.2 -0.8 0.0 -1.2 -1.4 -0.1 -1.2 -0.3 -0.3 0.5 -1.1 -2.1 1.0 -1.1 -0.0 -0.0 -0.0 -0.0 -0.8 -0.8 -1.3 -0.7 -0.7 -1.6
Medication: Levothyroxine sodium 0.3 0.5 2.4 -1.3 -0.8 0.2 1.5 -0.7 -0.6 -0.4 -0.1 0.3 0.3 0.6 -0.9 -0.7 -0.7 -0.7 -0.8 -0.7 -0.1 0.3 -0.4 -1.0 -0.7 -0.1
Sitting height 3.2 23.1 40.1 3.3 3.8 6.0 6.3 4.3 4.5 1.1 4.6 4.7 4.8 5.5 -6.0 5.1 3.7 4.1 3.9 4.0 5.9 6.0 4.0 4.2 5.3 6.0
Chronic bronchitis/emphysema (father) 0.9 1.0 2.1 -0.6 1.3 0.6 1.1 1.2 -0.7 0.6 1.5 0.6 1.3 1.2 -0.9 0.7 1.2 1.3 1.1 1.1 1.0 0.7 1.4 0.7 0.9 0.5
High blood pressure (mother) 3.9 5.4 11.8 -2.8 -2.2 -2.6 -1.8 -2.5 -1.8 0.2 -2.3 -1.9 -2.0 -1.9 2.5 -1.8 -2.4 -2.3 -2.5 -2.4 -2.2 -2.5 -3.4 -2.4 -3.1 -2.2
Body mass index (BMI) 2.1 9.0 22.5 -1.4 -2.3 -3.7 -2.8 -2.7 -4.7 2.1 -2.5 -2.2 -4.0 -2.1 3.2 -3.0 -2.4 -2.5 -2.2 -2.8 -3.7 -3.6 -2.2 -3.9 -2.7 -3.7
Impedance of leg (left) 0.7 3.2 11.8 -1.8 0.9 2.7 3.3 1.0 0.4 -3.4 0.9 1.6 0.3 1.8 -2.7 1.1 0.7 0.6 0.6 0.6 2.2 3.3 1.3 1.2 0.5 1.7
Leg predicted mass (left) 0.1 0.4 3.7 1.1 -0.3 -0.7 0.3 -0.5 0.4 1.9 0.2 0.0 1.3 0.2 -0.0 0.0 -0.5 -0.2 -0.3 -0.3 -0.2 -0.4 -0.6 -0.7 0.6 0.2
Trunk fat mass 0.6 2.5 10.4 -1.0 -1.3 -1.7 -0.6 -1.6 -3.2 1.3 -1.2 -1.0 -2.1 -0.8 0.9 -1.7 -1.5 -1.5 -1.2 -1.8 -1.5 -1.0 -1.1 -2.6 -1.2 -1.9
Waist circumference 0.9 3.2 7.6 -0.5 -1.3 -2.5 -1.8 -1.6 -2.6 1.3 -1.3 -1.1 -2.8 -0.9 2.0 -1.7 -1.4 -1.4 -1.3 -1.6 -2.3 -2.1 -1.7 -2.3 -1.4 -2.1
Number of incorrect matches in round 1.8 3.0 5.1 -1.7 -1.7 -2.0 -1.6 -1.7 -0.4 -2.2 -1.9 -1.3 -2.0 -1.9 1.7 -1.8 -1.5 -1.7 -1.7 -1.6 -2.0 -1.9 -1.6 -1.2 -2.0 -1.9
Past tobacco smoking 1.1 2.0 8.1 -2.6 -0.9 0.0 1.0 -1.1 -2.4 -1.3 -1.3 -0.7 -1.3 0.4 0.1 -1.8 -1.4 -1.5 -1.0 -1.7 -0.8 0.3 -2.9 -1.7 -1.2 -0.5
Alcohol usually taken with meals 0.4 0.7 3.5 -1.9 -0.6 0.3 1.1 -0.8 -1.1 0.4 -0.8 -0.5 -0.7 0.3 -0.2 -0.8 -0.8 -1.1 -0.7 -1.2 -0.9 -0.1 -0.7 -0.9 -0.7 -0.4
Nervous feelings 0.9 1.6 7.0 0.1 -1.3 -1.1 -1.8 -0.9 1.1 -2.6 -1.4 -0.4 -2.6 -0.5 1.2 -0.9 -0.7 -0.8 -1.0 -0.5 -1.3 -1.5 -1.6 0.3 -0.7 -0.9
Frequency of tenseness / restlessness in last 2 weeks 1.2 1.9 7.2 0.7 1.9 -0.3 -1.4 1.7 1.8 -1.0 1.5 0.7 0.2 -0.8 1.0 1.6 2.0 1.9 1.7 2.2 -0.3 -1.0 0.5 2.7 0.3 0.3
Hearing difficulty/problems with background noise 1.3 2.1 5.5 1.1 1.1 1.4 0.4 1.3 2.2 -1.3 1.3 0.5 0.1 2.4 -0.9 2.0 1.4 1.7 1.3 1.7 1.0 0.5 0.6 2.2 1.9 1.6
Hair/balding pattern: Pattern 2 2.1 2.6 8.8 -0.3 1.7 2.2 2.5 0.9 -0.3 -0.1 2.3 1.4 3.0 2.5 -2.0 0.6 0.7 0.9 0.7 0.6 2.0 2.3 0.6 0.6 1.6 1.9
Had menopause 0.7 0.9 2.7 0.8 0.7 1.2 0.8 0.7 -0.6 1.6 0.8 0.3 1.4 1.2 -1.3 0.6 0.6 0.8 0.9 0.6 1.1 1.1 0.9 0.4 1.5 0.5
Had other major operations 0.7 0.8 2.6 -0.2 -1.1 -1.0 -0.6 -0.8 -1.6 1.1 -0.9 -0.3 -1.1 -0.4 1.0 -0.7 -0.7 -0.7 -0.6 -0.9 -0.9 -1.1 -0.2 -0.8 -1.4 -0.8
Forced vital capacity (FVC) 16.6 63.8 86.6 6.8 8.4 8.3 8.0 8.8 6.9 1.7 8.2 8.3 6.3 6.3 -8.8 8.5 8.3 8.7 8.3 8.7 9.3 7.8 8.0 8.6 8.6 8.7
Heel bone mineral density (BMD) T-score, automated (right) 0.8 1.7 4.9 0.6 -1.6 -1.8 -0.4 -2.0 0.5 -0.1 -1.4 -0.6 -1.3 -2.2 0.8 -0.9 -1.8 -1.5 -1.5 -1.6 -1.2 -1.2 -1.4 -1.1 -1.3 -0.7
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 2.0 0.1 0.2 -1.1 -1.4 0.3 -0.0 -0.7 -0.0 -0.3 -0.4 -0.2 0.8 -0.2 0.6 0.5 0.6 0.6 -0.8 -1.2 0.5 0.2 -0.1 -1.0
Qualifications: None of the above 0.3 0.6 2.9 0.2 0.6 -0.9 -1.7 0.8 -1.0 -0.9 0.6 -0.0 0.3 -1.1 0.5 0.2 0.9 1.0 0.9 0.9 0.4 0.1 -0.3 0.3 -0.2 -0.8
Financial difficulties in last 2 years 1.8 2.4 4.4 1.0 1.5 1.0 1.1 1.8 1.2 -1.7 1.5 1.9 1.0 -0.2 -1.8 0.9 1.6 1.9 1.8 1.9 2.1 1.6 1.0 2.0 1.8 1.5
Mouth/teeth dental problems 0.3 0.5 3.9 0.6 0.1 0.4 -0.0 0.0 -1.4 2.0 -0.8 -1.0 -1.3 -0.5 -0.1 -0.8 -0.1 -0.3 0.2 -0.4 0.1 0.5 -0.3 -0.2 -0.2 -0.4
Heart attack 0.8 1.0 3.8 -0.2 -0.6 -1.2 -1.9 -0.7 1.2 -0.1 -0.7 -1.9 -0.0 -1.2 1.4 0.3 -0.4 -0.5 -0.4 -0.1 -1.3 -1.6 -0.9 0.0 -0.7 -1.1
Allergy 1.1 2.6 4.9 0.2 1.7 1.6 1.4 1.5 1.6 0.2 2.0 2.0 2.2 2.0 -1.3 2.1 1.4 1.6 1.4 1.5 1.7 1.5 1.0 1.8 1.4 2.2
Pain all over the body in last month 0.3 0.3 1.2 -0.1 0.3 0.2 0.6 0.2 0.7 -0.8 0.4 0.8 1.0 0.6 -0.8 0.3 0.1 0.2 -0.2 0.3 1.1 0.6 -0.1 0.4 0.4 0.3
Diabetes (self-reported) 3.9 6.1 19.0 -1.8 -2.3 -2.9 -3.0 -2.6 -0.6 -0.7 -2.6 -2.5 -2.6 -2.1 4.4 -1.0 -2.3 -2.5 -2.7 -2.3 -3.1 -3.2 -1.6 -1.5 -2.8 -2.2
Hayfever/allergic rhinitis (self-reported) 0.9 1.2 2.0 -1.3 -1.1 -0.8 -1.1 -1.2 -0.3 -0.0 -1.4 -1.2 -0.9 -1.0 1.3 -1.1 -1.3 -1.4 -1.3 -1.4 -1.0 -0.5 -1.2 -0.7 -1.4 -0.9
Medication: Ramipril 0.3 0.4 2.3 0.7 -0.4 -0.5 -0.6 -0.4 0.6 1.0 -0.8 -0.9 -1.5 -0.6 0.5 0.8 -0.2 -0.1 -0.1 -0.1 -0.4 -0.7 -0.7 0.7 0.2 0.0
Medication: Simvastatin 1.3 1.9 3.5 -0.7 -1.5 -1.1 -0.8 -1.9 -1.8 0.4 -1.6 -1.1 -1.2 -0.4 1.3 -1.1 -1.6 -1.6 -1.6 -1.5 -1.7 -1.4 -1.5 -1.5 -1.5 -1.5
Fluid intelligence score 0.2 0.5 1.4 0.0 -1.2 0.0 0.5 -1.2 -0.0 0.5 -1.0 -0.6 -0.6 0.6 -0.1 -0.2 -1.2 -1.1 -1.0 -1.2 -0.3 0.0 -0.1 -0.9 -0.2 0.0
Illnesses of siblings 0.7 1.0 4.3 0.2 -0.3 1.1 2.1 0.1 0.6 -1.9 -0.4 0.4 1.4 -0.5 -2.0 0.1 -0.3 -0.2 -0.1 -0.1 1.3 1.8 0.6 0.5 0.8 0.8
Neuroticism score 1.1 2.3 14.0 0.3 -1.0 -1.9 -2.1 -0.7 2.7 -3.7 -1.0 -0.9 -0.8 -1.9 1.8 -0.4 -0.5 -0.5 -1.0 -0.0 -1.3 -2.0 -1.2 1.5 -0.7 -0.8
Weight 0.2 1.0 4.0 0.0 -0.9 -1.1 0.2 -1.1 -2.0 1.6 -0.6 -0.4 -0.9 -0.0 0.3 -0.7 -1.1 -0.9 -0.8 -1.2 -0.9 -0.6 -1.1 -2.0 -0.3 -0.9
Impedance of arm (right) 0.8 3.9 9.8 0.2 1.7 3.0 2.1 2.1 1.7 -1.5 1.9 1.2 2.6 1.2 -2.2 1.0 1.7 1.7 1.5 1.8 2.7 3.1 2.0 1.9 1.7 2.2
Arm fat percentage (right) 1.5 6.0 19.8 -1.0 -1.7 -2.8 -2.3 -1.9 -4.5 1.8 -1.9 -1.7 -3.5 -1.9 2.7 -2.9 -1.7 -1.8 -1.5 -2.2 -2.9 -2.6 -1.5 -3.4 -2.2 -3.0
Trunk fat-free mass 0.2 1.0 4.0 1.3 -0.1 0.4 2.0 -0.2 1.4 1.1 0.6 0.8 1.7 1.1 -1.2 1.0 -0.3 0.0 -0.1 -0.1 0.8 1.0 -0.6 -0.1 1.2 1.6
Hip circumference 1.1 4.8 15.1 -0.8 -2.4 -2.6 -1.4 -2.2 -3.9 0.3 -2.3 -1.8 -2.6 -1.3 1.5 -2.3 -2.2 -2.2 -1.8 -2.5 -2.3 -2.0 -2.0 -3.1 -1.4 -2.8
Time employed in main current job 0.5 0.6 3.1 -1.1 -0.1 -0.4 0.0 -0.8 -0.3 1.8 -0.0 -0.9 1.5 -1.2 0.4 -0.7 -0.7 -0.6 -0.5 -0.7 -0.6 -0.3 -0.7 -0.3 -0.5 -0.1
Alcohol intake versus 10 years previously 0.7 1.1 2.5 0.1 1.2 0.0 -0.5 1.3 -0.1 1.3 1.6 1.4 -0.2 1.1 1.1 1.3 1.4 1.3 1.4 1.2 0.3 -0.3 1.3 1.0 -0.2 0.8
Father’s age at death 0.5 0.7 3.1 -1.0 -0.5 0.7 1.1 -0.4 -1.2 -0.9 -0.8 -0.4 -0.6 1.7 -1.1 -0.6 -0.7 -0.8 -0.6 -1.0 0.7 1.3 -0.6 -0.6 0.0 0.4
Worrier / anxious feelings 3.0 5.6 10.7 -1.0 -3.0 -2.5 -2.8 -2.4 0.1 -2.6 -2.9 -2.3 -3.3 -2.4 2.6 -2.4 -2.2 -2.3 -2.2 -1.9 -2.6 -2.7 -3.0 -0.8 -1.8 -2.3
Frequency of tiredness / lethargy in last 2 weeks 1.1 1.7 8.3 -0.9 -0.4 -1.5 -1.0 -0.8 -0.9 -2.4 -0.9 -0.5 -2.9 -1.4 1.6 -0.9 -0.4 -0.6 -0.8 -0.4 -1.7 -2.2 -0.6 -0.3 -0.9 -1.7
Falls in the last year 0.8 1.1 4.7 0.4 0.1 -1.8 -2.2 0.2 -0.6 -0.0 -0.2 -0.3 -1.9 -0.7 1.3 0.1 0.5 0.5 0.5 0.7 -1.4 -2.0 -1.1 0.2 -0.7 -1.6
Hair/balding pattern: Pattern 3 1.7 2.5 9.5 0.2 1.8 1.4 1.7 1.6 0.4 3.1 2.0 1.4 2.6 1.1 -1.8 0.5 1.7 1.7 1.8 1.7 1.2 1.2 1.8 0.2 1.5 0.6
Number of live births 0.3 0.4 2.3 0.2 1.0 0.7 0.2 0.6 -0.8 1.0 1.0 0.2 0.1 1.5 0.2 0.4 0.6 0.5 0.6 0.5 0.5 0.6 0.2 0.1 0.3 0.5
Forced expiratory volume in 1-second (FEV1) 10.6 35.7 48.7 4.7 6.4 6.2 6.3 6.6 4.8 1.0 6.2 6.5 4.4 4.9 -6.5 6.6 6.2 6.5 6.2 6.4 7.0 5.9 6.0 6.1 6.3 6.7
Pulse rate 0.8 1.4 3.8 -0.7 -1.4 -0.7 0.4 -1.6 -1.4 -0.2 -1.5 -0.9 -0.8 -0.6 0.5 -1.9 -1.7 -1.8 -1.5 -1.7 -1.2 -0.2 -1.2 -0.9 -1.2 -0.9
Happiness 3.0 3.6 8.0 0.0 2.5 2.0 2.8 2.0 -0.5 1.1 2.8 2.8 1.0 2.5 -2.3 1.4 2.0 2.0 1.8 1.9 1.7 1.3 1.0 0.9 2.4 1.6
Noisy workplace 0.3 0.3 2.0 0.0 -0.7 -0.8 -1.4 -0.2 0.8 -0.4 -0.6 0.0 -0.3 -0.9 0.5 0.3 -0.1 0.1 -0.0 0.1 -0.4 -0.8 -0.2 0.1 -0.7 -0.6
Qualifications: A levels/AS levels or equivalent 0.2 0.4 1.4 1.0 -0.0 -0.1 -0.5 -0.4 0.2 0.8 -0.5 -0.6 -0.7 0.7 0.8 0.3 -0.2 -0.5 -0.2 -0.4 -1.2 -1.0 0.6 0.0 -0.6 -0.3
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.6 2.4 1.2 -0.1 0.4 0.9 0.2 -0.4 1.1 0.4 1.4 -1.5 1.5 -0.9 0.2 0.2 0.4 0.3 0.2 0.6 0.5 0.1 0.0 0.9 0.5
Mouth/teeth dental problems: Dentures 0.6 1.0 2.5 0.2 1.4 0.2 -0.4 1.2 1.6 -1.5 1.2 1.3 0.7 0.2 -0.3 0.6 1.3 1.4 0.9 1.4 0.4 0.3 0.8 1.4 0.2 0.4
Asthma 0.7 1.4 7.4 0.9 -0.5 -1.5 -2.4 -0.6 -0.6 0.1 -0.6 -1.2 -1.1 -0.9 1.8 -1.1 -0.2 -0.3 -0.2 -0.0 -1.9 -2.7 0.0 -0.3 -0.5 -1.8
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.6 2.2 -0.7 0.8 -0.5 -0.6 1.1 0.5 -0.5 0.4 0.1 0.7 -1.4 0.9 0.6 1.1 1.0 0.6 1.0 -0.1 -0.5 1.5 0.9 -0.1 -0.0
Medication: Cholesterol lowering 0.8 1.3 3.6 0.1 -1.2 -1.2 -0.8 -1.3 -1.1 0.6 -1.3 -0.9 -0.8 -1.7 1.4 -0.6 -1.2 -1.1 -1.1 -1.1 -1.1 -0.9 -1.9 -1.4 -1.2 -0.5
Depression (self-reported) 0.2 0.3 1.5 0.8 -0.8 0.4 -0.0 -0.2 0.9 -1.2 -0.6 -0.3 -0.4 -0.0 -0.1 -0.6 -0.2 -0.2 -0.1 -0.1 0.2 0.7 0.6 0.1 0.3 0.1
Medication: Lansoprazole 1.7 1.9 11.1 -0.9 -1.2 -1.6 -1.1 -1.1 -0.3 -3.3 -1.7 -0.6 -1.6 -2.0 1.3 -1.0 -1.1 -1.3 -1.5 -1.2 -1.2 -1.3 -0.3 -0.6 -1.3 -1.3
Prospective memory result 0.5 0.6 1.8 1.2 0.5 0.2 0.2 0.7 1.3 0.4 0.9 1.3 1.0 -0.6 -0.6 0.4 0.7 0.9 0.7 1.0 0.7 0.5 0.4 1.0 0.2 0.6
Lung cancer (father) 1.7 2.0 5.7 1.9 1.5 1.3 0.4 1.6 0.2 1.4 1.7 0.9 0.4 1.4 -1.1 1.0 1.7 1.8 1.8 1.8 1.4 0.9 1.4 1.0 2.4 1.4
Illnesses of mother 3.8 4.7 8.7 2.9 1.9 2.5 1.6 2.1 2.3 0.7 2.0 1.4 1.2 2.0 -2.0 2.3 2.1 2.1 2.2 2.2 2.1 1.8 2.9 2.9 2.8 2.5
Forced expiratory volume in 1-second (FEV1), Best measure 9.8 31.3 45.3 4.7 5.8 6.1 5.9 6.1 4.6 0.6 5.5 5.8 3.2 4.5 -6.2 6.4 5.7 5.9 5.6 5.8 6.7 5.8 5.6 6.1 6.2 6.5
Pulse wave Arterial Stiffness index 0.3 0.3 1.5 -0.5 -0.6 -0.7 -0.5 -0.4 -0.2 -1.2 -0.5 -0.6 0.5 -0.3 0.2 -0.6 -0.4 -0.3 -0.4 -0.3 -0.4 -0.6 -0.6 -0.4 -0.5 -0.7
Impedance of arm (left) 0.7 3.2 7.9 -0.5 1.4 2.8 1.7 1.8 1.5 -1.8 1.6 0.5 2.8 1.7 -2.1 1.1 1.5 1.5 1.3 1.5 2.4 2.8 1.7 1.8 1.4 1.8
Arm fat mass (right) 1.1 4.5 13.6 -0.8 -1.7 -2.5 -1.6 -2.0 -3.7 1.7 -1.7 -1.5 -2.8 -1.5 2.1 -2.3 -1.9 -1.9 -1.6 -2.2 -2.4 -2.0 -1.6 -3.1 -1.8 -2.4
Trunk predicted mass 0.2 1.2 4.5 1.4 0.0 0.6 2.1 -0.1 1.5 1.2 0.7 0.9 1.9 1.3 -1.3 1.1 -0.2 0.1 -0.0 0.1 1.0 1.1 -0.5 -0.1 1.3 1.7
Standing height 1.9 18.8 39.4 3.0 2.6 5.2 6.3 2.9 5.5 -0.6 3.8 3.6 6.2 4.2 -5.9 4.5 2.3 2.9 2.5 3.0 5.6 6.0 2.1 3.7 4.8 5.9
Length of working week for main job 2.9 3.2 6.0 -2.4 -2.0 -1.7 -0.6 -2.0 -1.6 -2.0 -2.0 -1.4 -0.7 -1.3 0.7 -1.8 -2.1 -2.1 -2.1 -1.9 -1.5 -0.8 -1.9 -2.2 -2.2 -2.2
Exposure to tobacco smoke at home 0.7 0.8 1.9 0.1 1.1 -0.2 -0.8 1.1 1.3 -0.9 1.0 0.1 1.2 -0.6 0.4 0.8 1.2 1.3 1.2 1.4 0.2 -0.1 0.1 1.3 -0.0 0.1
Breastfed as a baby 0.3 0.4 3.0 -0.1 0.2 0.8 1.7 0.1 -0.4 1.3 0.0 0.0 0.3 -0.0 -0.9 0.1 -0.1 -0.2 0.1 -0.3 0.7 0.9 0.8 -0.5 -0.0 0.9
Tense / ‘highly strung’ 0.6 1.0 3.0 -0.4 -0.7 -1.4 -1.7 -0.6 1.4 -1.5 -0.7 0.6 -1.2 -1.2 1.4 0.1 -0.3 -0.2 -0.5 0.2 -1.0 -1.4 -1.7 0.7 -0.5 -0.8
Seen doctor (GP) for nerves, anxiety, tension or depression 3.6 5.5 13.9 2.3 1.3 2.3 1.5 2.3 3.7 -3.7 1.5 1.4 1.6 1.4 -2.2 2.0 2.0 2.3 1.8 2.4 3.0 2.6 2.6 3.2 2.3 2.3
Hair/balding pattern: Pattern 4 1.7 4.0 30.9 0.8 -1.7 -1.5 -1.6 -1.0 1.1 -5.6 -2.6 -0.8 -5.3 -1.1 0.9 0.4 -0.9 -1.0 -1.1 -0.5 -0.9 -1.5 -1.6 1.8 -1.2 -0.7
Birth weight of first child 0.4 0.8 1.7 0.6 1.1 0.6 -0.1 1.3 1.2 1.0 1.3 1.1 0.7 0.8 -0.1 0.8 1.2 0.9 1.1 0.9 0.6 0.7 0.9 0.4 1.1 0.9
Peak expiratory flow (PEF) 0.1 0.3 1.4 -0.4 0.6 0.2 1.2 0.4 -0.9 -1.1 0.0 0.6 -1.2 0.8 -0.6 0.5 0.4 0.2 0.4 0.2 -0.2 0.0 0.2 -0.2 0.5 -0.3
Pulse wave reflection index 0.2 0.2 3.7 -0.7 -0.1 -0.4 -0.4 0.2 0.4 -1.9 0.0 -0.2 0.5 -0.1 -0.1 -0.4 0.2 0.3 0.0 0.3 0.0 -0.2 -0.2 -0.4 0.2 -0.3
Ever highly irritable/argumentative for 2 days 0.8 0.9 3.1 -0.6 1.2 0.2 -0.7 1.3 0.8 -0.7 1.2 0.4 0.8 0.6 -0.4 0.7 1.5 1.6 1.4 1.8 0.5 0.0 0.8 1.4 0.6 -0.4
Loud music exposure frequency 0.8 0.9 4.0 1.2 0.7 -0.2 0.1 0.7 1.5 -0.9 0.9 0.4 0.3 0.6 -0.3 1.3 0.9 0.8 0.7 1.2 0.0 -0.8 1.0 1.6 2.0 0.2
Qualifications: O levels/GCSEs or equivalent 0.5 0.8 3.4 -1.1 -0.2 -1.1 -1.4 -0.4 0.4 -0.5 -0.4 -0.2 -0.8 0.3 1.7 -0.2 -0.1 -0.4 -0.4 -0.3 -1.7 -1.8 -0.5 -0.9 -1.2 -0.8
Mouth/teeth dental problems: Bleeding gums 1.0 1.3 8.5 -0.1 -0.3 1.2 1.9 -0.2 1.6 0.5 0.7 0.5 2.9 1.9 -1.2 1.3 -0.3 -0.1 -0.3 -0.1 1.1 1.3 0.5 -0.2 0.1 1.4
Blood clot in the leg (DVT) 0.6 0.8 6.3 0.2 -0.2 0.1 1.6 -0.7 -2.2 2.5 -0.3 0.1 -0.5 -0.2 -1.0 -0.3 -0.7 -0.7 -0.5 -0.8 -0.0 0.2 0.1 -1.0 -0.3 -0.1
Medication: Paracetamol 0.7 1.2 3.0 -0.1 1.4 -0.8 -1.6 1.6 0.6 -0.6 1.1 0.0 0.8 -1.0 1.6 0.9 1.7 1.5 1.3 1.6 -0.5 -1.5 0.8 1.0 0.1 -0.3
Headache pain in last month 3.2 5.6 14.7 -3.8 -2.5 -2.8 -2.3 -2.2 -0.7 -2.3 -2.1 -1.8 0.5 -1.9 2.6 -2.6 -2.2 -2.4 -2.5 -2.0 -2.4 -2.2 -2.2 -2.0 -3.1 -2.8
Medication for cholesterol, blood pressure or diabetes 5.3 8.8 16.1 2.2 3.0 3.5 2.8 3.3 2.0 0.8 3.2 2.5 2.4 3.2 -3.3 2.8 2.9 3.0 3.0 2.8 3.6 3.2 4.0 3.0 3.1 3.0
Glaucoma (self-reported) 1.6 1.9 5.3 -0.4 -1.4 -1.1 -1.4 -1.3 -2.3 1.4 -1.3 -2.0 -0.4 -0.9 1.5 -1.6 -1.3 -1.3 -1.0 -1.5 -1.4 -1.1 -1.3 -1.6 -1.1 -1.3
Gout (self-reported) 0.6 0.8 4.4 0.5 -1.3 -0.9 -0.2 -1.0 0.8 -0.8 -0.8 -0.1 -0.1 -2.1 0.4 -1.0 -1.0 -0.8 -1.1 -0.9 -0.3 -0.5 -1.3 -0.9 -0.5 0.0
Hypothyroidism/myxoedema (self-reported) 0.1 0.3 2.0 -1.4 -0.2 -0.0 1.4 -0.2 -0.0 -0.8 -0.0 0.5 -0.2 -0.3 -0.6 -0.1 -0.2 -0.1 -0.5 -0.2 0.1 0.2 0.1 -0.2 -0.6 -0.1
Medication: Amlodipine 0.5 0.6 5.2 0.0 -0.1 -0.8 -0.9 -0.5 -0.2 1.0 -0.4 0.5 -2.3 -0.9 0.7 -0.3 -0.3 -0.1 -0.4 -0.1 -0.9 -1.3 -1.4 -0.0 -0.4 -0.6
Medication: Ventolin 100micrograms inhaler 0.3 0.4 4.5 0.1 0.4 0.1 -0.8 0.2 -0.2 2.1 0.4 -0.7 -0.4 0.4 1.1 0.5 0.4 0.1 0.3 0.2 -0.7 -0.8 0.2 0.2 -0.2 -0.4
Birth weight 0.3 0.7 3.2 0.3 -0.6 0.0 -0.7 -0.7 -1.0 0.6 -1.0 -1.8 -1.1 -1.4 0.1 -0.4 -0.7 -0.7 -0.6 -0.9 -0.0 0.3 -1.2 -0.9 0.4 -0.3
Chronic bronchitis/emphysema (mother) 0.9 1.0 6.3 0.6 0.6 0.3 0.2 0.9 1.0 -1.7 0.8 1.2 0.1 2.5 -0.4 1.2 0.9 1.0 0.6 1.1 0.3 0.2 1.4 1.2 0.4 0.4
High blood pressure (siblings) 1.5 2.2 7.0 -0.9 -0.9 -1.7 -2.0 -1.0 -1.8 1.0 -1.0 -0.8 -2.6 -0.3 2.2 -1.1 -0.8 -0.9 -0.8 -1.1 -2.1 -2.3 -1.0 -1.7 -1.5 -1.6
Forced vital capacity (FVC), Best measure 14.1 51.6 75.1 6.4 7.3 7.9 7.5 7.7 6.3 1.2 6.9 7.1 4.8 5.6 -8.3 7.8 7.2 7.6 7.2 7.5 8.7 7.4 7.2 8.0 8.0 8.0
Body fat percentage 1.3 5.2 20.9 -2.0 -1.6 -2.4 -1.5 -2.0 -4.6 0.9 -1.9 -1.5 -3.6 -1.4 1.8 -2.6 -1.8 -1.9 -1.6 -2.2 -2.4 -1.8 -1.4 -3.3 -2.1 -2.9
Leg fat percentage (right) 1.5 5.4 20.3 -2.3 -1.6 -2.2 -1.2 -2.1 -4.5 1.4 -2.0 -1.3 -4.1 -1.2 1.8 -2.1 -1.8 -2.0 -1.7 -2.4 -2.5 -1.8 -1.4 -3.1 -2.5 -2.7
Arm fat-free mass (right) 0.1 0.5 2.2 0.4 -0.5 -0.3 1.5 -0.7 0.1 1.1 0.1 0.7 0.9 1.1 -0.8 0.5 -0.7 -0.5 -0.4 -0.6 0.1 0.3 -0.8 -0.8 0.5 0.5
Exposure to tobacco smoke outside home 0.4 0.5 1.6 1.2 0.7 -1.0 -0.7 0.5 0.1 0.5 0.5 -0.3 -0.1 -0.7 0.6 0.1 0.8 0.8 0.7 0.9 -0.4 -1.2 0.8 1.1 0.2 -0.4
Comparative body size at age 10 2.9 8.0 15.1 -2.3 -2.8 -2.9 -2.5 -3.1 -3.7 1.6 -2.8 -3.5 -0.7 -2.0 2.2 -3.1 -3.0 -2.9 -2.9 -3.2 -2.6 -2.8 -2.0 -3.9 -2.7 -3.6
Number of full brothers 1.6 2.0 6.9 -1.6 -0.6 -1.7 -2.3 -0.7 -1.8 -0.1 -0.5 -2.6 0.4 -0.6 1.9 -1.7 -0.7 -0.6 -0.7 -0.7 -1.4 -1.8 -1.1 -1.5 -1.6 -2.0
Worry too long after embarrassment 0.4 0.6 5.9 -0.1 -0.6 -0.8 -0.5 -0.6 0.7 -2.4 -0.9 -0.6 -0.8 -0.9 0.4 -0.0 -0.5 -0.4 -0.8 -0.4 -0.4 -0.8 -0.9 1.1 0.1 -0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 1.5 2.0 6.8 2.1 0.7 1.3 0.5 1.3 2.1 -1.4 1.0 1.5 0.4 1.6 -1.3 1.4 1.2 1.4 1.1 1.5 1.5 1.1 1.1 2.6 1.6 1.3
Wheeze or whistling in the chest in last year 1.1 2.0 9.9 -0.0 0.1 -2.0 -3.1 -0.1 -0.4 0.6 -0.1 -0.0 -2.0 -1.3 3.0 -0.9 0.3 0.1 0.1 0.3 -2.1 -2.5 -0.0 -0.1 -1.0 -1.8
Number of children fathered 1.4 1.6 3.9 -2.0 -1.2 -0.9 -0.3 -1.4 -1.4 -0.5 -1.2 -0.8 -1.6 -0.1 1.1 -0.4 -1.2 -1.3 -1.3 -1.4 -1.8 -1.4 -1.9 -1.2 -1.3 -0.8
Reason for reducing amount of alcohol drunk: Health precaution 1.3 1.5 8.1 2.8 0.9 1.3 0.5 1.1 0.7 1.0 0.6 0.3 1.5 -0.1 -1.1 0.6 1.1 1.2 1.3 1.2 1.3 1.0 0.9 1.8 1.4 1.3
Age at first live birth 1.2 2.2 4.9 -1.7 -1.8 -1.6 -1.2 -1.5 0.1 -1.4 -2.2 -1.5 -0.3 -2.2 1.0 -0.8 -1.6 -1.8 -1.4 -1.8 -1.4 -1.2 -1.1 -1.3 -1.8 -1.4
Pulse wave peak to peak time 0.5 0.6 2.0 0.7 0.7 1.1 0.9 0.6 0.5 1.4 0.8 0.8 -0.2 0.7 -0.5 0.9 0.5 0.5 0.6 0.4 0.7 1.0 0.8 0.5 0.8 1.1
Health satisfaction 0.6 0.8 3.0 0.1 1.4 0.3 1.2 0.9 0.2 0.9 1.2 1.7 0.1 0.3 -0.3 1.4 1.1 1.1 1.1 1.1 0.3 -0.1 0.5 0.7 0.2 0.7
Shortness of breath walking on level ground 0.5 0.6 3.2 0.1 0.3 -0.8 -1.1 0.4 -0.1 -0.3 -0.1 -0.4 -1.4 -1.8 0.6 -0.2 0.6 0.4 0.6 0.5 -0.7 -1.1 1.0 0.4 -0.5 -1.0
Qualifications: College or University degree 0.4 1.4 4.2 0.2 -1.5 1.2 2.1 -1.4 -0.2 -0.6 -1.7 -1.5 -0.3 0.7 -1.5 -1.0 -1.6 -1.6 -1.3 -1.7 0.0 0.9 -0.2 -0.8 0.7 0.5
Eye problems/disorders: None of the above 0.4 0.5 1.3 0.8 0.5 0.7 0.6 0.6 1.2 -0.2 0.2 0.4 -0.7 -0.2 -0.6 1.1 0.4 0.5 0.5 0.4 1.0 0.9 -0.3 0.9 0.9 1.0
Mouth/teeth dental problems: Loose teeth 0.5 0.6 3.3 0.2 -0.2 0.3 1.6 -0.2 -1.2 -0.5 0.3 0.6 0.6 0.3 -1.8 -0.4 -0.5 -0.1 -0.3 -0.3 1.4 1.4 -0.0 -0.6 0.5 0.1
Emphysema/chronic bronchitis 0.2 0.2 3.5 -0.2 -0.1 -0.2 -0.2 0.3 0.3 -0.9 -0.2 0.2 -1.9 0.5 0.4 0.1 0.4 0.2 0.1 0.3 -0.2 0.1 0.3 0.0 -0.0 -0.2
Medication for pain relief, constipation, heartburn 2.3 3.9 10.9 -0.1 -3.1 -0.6 0.5 -3.2 -0.6 -0.5 -2.5 -1.5 -1.1 0.8 -0.5 -2.7 -3.3 -3.1 -2.8 -3.1 -1.2 -0.0 -2.2 -2.3 -1.3 -0.9
Neck or shoulder pain in last month 1.1 1.6 5.4 0.4 1.9 0.4 0.4 1.6 1.3 -0.4 1.4 2.3 -0.9 -0.5 0.0 1.3 1.7 1.5 1.4 1.7 0.3 0.1 1.7 2.3 -0.1 0.7
Medication: Blood pressure 4.0 7.1 15.2 -2.7 -2.3 -3.5 -2.7 -2.6 -1.6 -1.1 -2.5 -1.5 -2.0 -3.6 3.0 -2.8 -2.3 -2.2 -2.4 -2.1 -3.2 -3.1 -3.9 -2.6 -2.6 -3.1
Angina (self-reported) 1.5 2.0 11.8 -0.1 -1.4 -1.0 -2.2 -1.4 -0.9 -1.0 -1.8 -3.4 -0.4 -1.5 1.3 -0.6 -1.3 -1.4 -1.3 -1.4 -1.2 -0.9 -1.2 -0.5 -1.1 -1.4
Migraine (self-reported) 0.4 0.5 1.4 -1.2 -0.9 -0.5 0.2 -0.6 -0.7 -1.1 -0.7 0.5 -0.3 -0.4 0.1 -0.9 -0.6 -0.7 -0.7 -0.7 -0.7 -0.4 -0.5 -0.9 -0.7 -1.1
Medication: Ibuprofen 0.4 0.5 3.0 -1.0 0.6 -0.6 -0.6 0.7 0.5 -0.9 0.2 0.4 0.3 -1.7 1.0 0.2 0.7 0.6 0.3 0.7 -0.2 -0.5 0.8 0.6 -0.5 -0.2
Medication: Allopurinol 2.2 3.0 6.3 -0.4 -2.1 -2.0 -1.3 -2.2 -0.5 -0.8 -1.5 -1.1 -1.0 -2.5 1.4 -2.0 -2.1 -1.9 -2.1 -1.8 -1.8 -1.7 -2.5 -2.2 -1.3 -1.4
Medication: Omeprazole 2.4 2.9 5.7 0.2 1.9 1.7 1.1 2.2 1.4 0.9 1.9 2.4 0.7 1.3 -1.1 2.2 2.2 2.1 2.0 2.0 1.7 1.7 1.5 1.8 1.4 1.7
Medication: Seretide 50 evohaler 0.9 1.0 3.2 0.9 1.4 0.7 0.6 0.9 0.6 1.8 1.4 1.3 -0.0 1.0 -0.4 0.8 1.3 1.2 1.1 1.4 0.4 -0.2 1.1 0.9 1.4 0.4
Mean time to correctly identify matches 0.5 1.0 2.8 1.0 1.0 1.1 0.9 1.0 -0.3 0.6 0.8 1.4 -0.9 1.2 -1.1 1.2 1.0 1.1 0.9 1.1 1.0 0.4 1.1 0.9 1.7 0.8
Heart disease (mother) 0.2 0.3 1.0 -0.3 -0.3 -0.8 -0.2 -0.4 -0.7 -0.1 -0.6 0.2 -0.1 -0.5 0.2 -0.9 -0.5 -0.6 -0.4 -0.6 -0.4 -0.2 -0.4 -0.6 -1.0 -0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 8.7 10.4 17.0 -2.2 -4.1 -3.4 -2.3 -4.0 -1.7 -1.2 -3.8 -3.7 -2.3 -1.7 3.1 -3.5 -3.8 -3.9 -3.9 -3.8 -3.5 -3.2 -2.7 -3.2 -3.6 -3.1
Whole body fat mass 0.9 3.9 13.2 -1.2 -1.6 -2.2 -1.0 -2.0 -3.6 1.4 -1.7 -1.5 -2.5 -1.1 1.4 -2.0 -1.9 -1.9 -1.7 -2.2 -2.1 -1.6 -1.5 -3.0 -1.6 -2.3
Leg fat mass (right) 1.0 4.1 13.3 -1.5 -1.6 -2.3 -1.0 -2.0 -3.6 1.6 -1.7 -1.4 -2.8 -1.2 1.6 -1.9 -1.8 -1.8 -1.6 -2.2 -2.2 -1.7 -1.6 -3.0 -1.9 -2.2
Arm predicted mass (right) 0.1 0.5 2.5 0.7 -0.3 -0.1 1.6 -0.5 0.4 1.2 0.3 0.7 0.9 1.2 -0.9 0.5 -0.6 -0.3 -0.3 -0.4 0.3 0.4 -0.5 -0.7 0.7 0.8
Pulse rate, automated reading 1.6 5.3 12.2 -2.0 -2.9 -1.4 0.6 -3.2 -2.6 -0.5 -2.8 -0.3 -2.9 -0.9 1.4 -2.2 -3.2 -3.4 -3.0 -3.5 -2.2 -0.9 -2.2 -2.3 -2.3 -1.5
Alcohol intake frequency. 0.7 1.7 4.0 -1.7 -1.2 -1.4 -0.8 -1.4 -2.0 1.5 -0.9 -1.1 -1.0 -0.6 1.9 -0.4 -1.4 -1.3 -1.1 -1.7 -1.0 -0.8 -1.1 -1.4 -1.9 -0.9
Comparative height size at age 10 0.4 2.4 8.2 0.7 0.3 1.8 2.4 0.6 2.1 -0.6 1.1 1.0 2.7 0.8 -2.9 0.9 0.3 0.6 0.7 0.8 2.2 2.6 0.0 0.6 2.1 1.9
Number of full sisters 0.4 0.5 1.6 -0.3 0.5 1.0 0.6 0.8 0.9 -0.6 0.4 0.1 -0.9 1.1 -0.4 0.5 0.8 0.7 0.6 0.7 0.3 0.3 0.4 1.3 -0.0 0.4
Suffer from ‘nerves’ 0.5 0.8 5.5 -0.1 -0.5 -0.6 -1.1 -0.1 1.4 -2.4 -0.5 -0.6 -0.9 -1.1 0.8 -0.8 -0.1 -0.2 -0.3 0.2 -0.8 -0.4 -1.6 -0.0 -0.4 -0.6
Overall health rating 0.4 0.9 3.9 0.0 -0.3 -1.8 -0.5 -0.5 0.2 -1.8 -0.4 -0.1 -1.1 -2.0 1.7 -0.8 -0.3 -0.3 -0.5 -0.2 -1.1 -1.3 -0.6 0.2 -1.1 -0.6
Chest pain or discomfort 2.4 3.5 6.9 -0.7 -1.9 -2.2 -2.1 -2.1 -0.5 -1.5 -2.2 -2.6 -1.6 -1.6 2.2 -0.9 -1.9 -2.0 -2.1 -1.8 -2.1 -2.4 -1.8 -0.5 -2.1 -2.1
Had major operations 0.2 0.2 2.8 0.7 -0.2 0.2 -0.0 -0.3 1.7 0.4 0.0 -0.2 0.3 -0.1 -0.5 0.4 -0.1 -0.0 -0.1 0.2 0.2 -0.1 0.6 0.9 0.4 -0.2
Age at last live birth 0.2 0.3 1.4 -1.2 0.0 -0.7 -0.6 -0.0 -0.1 -1.0 -0.4 -0.3 -0.1 -1.1 0.6 0.2 -0.0 -0.2 0.0 -0.2 -0.6 -0.5 -0.4 -0.0 -1.0 -0.6
Family relationship satisfaction 1.3 1.5 5.4 0.3 1.2 1.2 1.3 1.1 -0.2 2.3 1.7 1.8 0.0 2.3 -0.9 1.2 1.2 1.2 1.2 1.0 0.8 0.8 0.7 0.3 1.2 1.4
Leg pain on walking 1.2 1.5 4.0 0.3 1.4 1.1 0.4 1.4 2.0 -0.1 1.4 0.1 1.5 0.4 -0.5 1.0 1.4 1.4 1.2 1.5 1.0 0.8 1.7 1.9 1.0 1.2
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.3 1.3 0.3 0.4 -0.2 -0.8 0.2 1.1 0.1 0.4 -0.6 0.6 0.4 0.6 0.8 0.4 0.4 0.2 0.6 -0.2 -0.7 0.2 0.6 -0.3 -0.0
Commuting to job workplace: Car/motor vehicle 0.9 1.0 4.8 0.3 1.6 0.6 0.4 1.1 0.3 2.2 1.6 1.8 1.1 0.6 -0.1 0.6 1.2 1.1 1.1 1.2 0.3 0.4 -0.1 0.8 -0.2 0.8
Illness, injury, bereavement, stress in last 2 years 0.2 0.2 0.8 -0.6 -0.3 0.3 0.2 -0.6 -0.4 0.3 -0.3 -0.1 0.6 -0.2 0.3 0.2 -0.6 -0.8 -0.9 -0.7 -0.3 0.3 0.0 -0.8 -0.3 -0.3
Medication: Aspirin 0.5 0.6 3.0 0.4 0.5 -0.8 -1.7 0.5 0.2 0.8 0.3 -0.2 -0.0 -1.1 1.6 1.5 0.6 0.5 0.5 0.7 -0.4 -0.7 0.2 0.5 -0.4 -0.3
Supplements: Vitamin C 0.3 0.4 1.6 -0.1 0.0 -0.4 -0.8 -0.2 -1.3 0.2 0.1 -0.8 -1.0 0.6 0.2 -0.1 -0.0 -0.1 -0.1 -0.1 -0.7 -1.1 -0.7 -0.6 0.4 -1.1
Knee pain experienced in last month 0.3 0.5 2.1 -0.1 0.9 -0.4 -0.4 0.8 -0.7 1.4 0.5 0.2 -1.2 -0.4 0.7 0.5 0.9 0.8 0.8 0.7 -0.2 -0.7 0.7 0.7 -0.4 -0.3
Hypertension (Self-reported) 6.8 19.0 33.6 -3.6 -4.4 -5.1 -4.0 -4.8 -3.4 0.4 -4.4 -3.1 -4.0 -3.9 5.0 -4.3 -4.4 -4.2 -4.5 -4.3 -5.1 -5.0 -5.8 -4.7 -4.5 -4.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.8 1.7 0.1 1.1 0.9 0.9 1.1 0.2 -0.4 0.9 1.3 0.3 -0.2 -0.9 1.2 1.0 1.1 1.0 1.1 1.2 0.8 0.2 1.1 1.0 0.8
Illnesses of father: Heart disease 0.4 0.5 2.6 1.1 0.9 0.3 0.3 0.5 -1.1 1.6 0.6 -0.2 -0.6 0.2 -0.4 0.7 0.6 0.7 0.9 0.5 0.1 -0.5 0.2 0.5 0.9 0.4
Illnesses of siblings: Diabetes 0.2 0.2 1.0 -1.0 -0.2 -0.1 -0.9 -0.2 0.3 0.1 0.0 0.3 -0.7 0.6 0.7 -0.5 -0.0 -0.1 -0.1 -0.1 -0.6 -0.1 -0.7 -0.5 -0.4 -0.7
Smoking status: Previous 0.9 1.4 4.7 1.8 0.7 0.2 -0.2 0.8 1.8 1.7 1.3 0.4 1.4 0.0 -0.4 1.8 1.1 1.2 0.8 1.4 0.9 0.1 2.2 1.1 1.5 0.9
Forced expiratory volume in 1-second (FEV1), predicted 1.0 2.0 4.9 -0.2 0.9 1.6 2.2 1.0 2.1 -1.7 1.1 0.9 2.1 2.2 -1.6 1.0 0.8 0.9 0.7 0.9 1.4 2.2 0.3 1.5 0.6 1.8
Whole body fat-free mass 0.1 0.6 2.2 1.2 -0.2 -0.1 1.3 -0.4 1.0 1.4 0.4 0.5 1.5 0.7 -0.6 0.6 -0.5 -0.1 -0.2 -0.2 0.3 0.3 -0.7 -0.4 0.9 1.0
Leg fat-free mass (right) 0.1 0.4 2.1 1.3 -0.4 -0.7 0.3 -0.5 0.7 1.4 0.1 -0.1 1.3 0.4 -0.1 0.0 -0.5 -0.2 -0.3 -0.2 -0.1 -0.4 -0.8 -0.6 0.7 0.2
Arm fat percentage (left) 1.6 6.5 21.0 -1.4 -1.8 -2.9 -2.5 -2.1 -4.6 1.7 -2.0 -2.1 -3.5 -1.6 2.7 -2.9 -1.8 -2.0 -1.6 -2.3 -3.0 -2.8 -1.6 -3.5 -2.3 -3.3
Average weekly red wine intake 0.3 0.4 2.1 0.5 0.3 0.9 1.4 0.2 -0.3 0.6 0.4 0.4 1.3 0.8 -1.0 0.0 0.1 0.2 0.3 0.0 0.5 0.8 -0.4 -0.4 0.5 1.0
Handedness (chirality/laterality): Left-handed 0.3 0.4 4.1 2.0 -0.1 -0.2 -0.7 0.2 0.7 0.7 -0.1 0.2 0.4 -1.1 -0.1 -0.3 0.2 0.2 0.4 0.4 0.3 0.3 -0.3 0.7 0.9 0.0
Mood swings 0.8 1.5 12.2 0.9 -0.7 -0.9 -1.3 -0.3 3.5 -2.8 -0.6 -0.9 0.6 -1.3 1.3 0.5 -0.2 -0.2 -0.6 0.2 -0.3 -0.8 -0.0 1.7 -0.6 0.1
Loneliness, isolation 1.5 2.1 5.3 1.1 1.8 0.6 0.6 1.7 2.3 -1.1 1.9 0.8 1.3 0.9 -0.7 1.8 1.7 1.6 1.6 1.7 1.1 0.5 1.2 2.3 1.1 1.8
Long-standing illness, disability or infirmity 0.3 0.4 2.1 1.5 0.5 -0.1 -0.3 0.7 0.4 0.9 0.3 0.3 -1.0 -0.4 0.2 0.3 0.7 0.9 0.6 0.8 0.5 -0.1 0.9 0.7 0.5 0.4
Ever had bowel cancer screening 0.7 0.8 3.2 0.7 0.1 -1.5 -1.8 0.2 1.7 -0.7 -0.0 1.0 -0.7 -0.3 1.4 0.2 0.3 0.3 0.1 0.6 -1.1 -1.6 -0.2 0.7 -0.1 -0.4
Diabetes diagnosed by doctor 1.4 2.3 10.6 -0.8 -1.4 -1.7 -1.9 -1.8 0.2 -0.3 -1.4 -1.2 -1.9 -0.6 3.2 -0.2 -1.5 -1.6 -1.8 -1.4 -2.0 -2.2 -0.5 -0.6 -1.7 -1.1
Ever had stillbirth, spontaneous miscarriage or termination 0.3 0.3 1.4 0.2 -0.0 0.7 0.4 -0.1 0.3 -0.9 -0.1 -1.0 0.8 -0.4 -1.2 0.2 -0.1 -0.0 0.0 -0.0 0.3 0.9 -0.6 0.0 0.5 0.1
Friendships satisfaction 2.4 2.9 6.8 1.2 2.0 1.7 2.3 1.8 1.6 1.0 2.0 2.6 0.9 1.2 -1.8 1.7 1.7 1.8 1.5 1.8 1.8 1.5 1.4 1.5 1.6 2.0
Qualifications: nursing, teaching 1.2 1.8 4.5 -1.0 -1.7 -0.6 0.1 -1.9 -1.4 -0.2 -1.9 -0.7 -1.2 -0.7 0.4 -1.2 -2.0 -2.1 -1.8 -2.1 -1.3 -0.9 -1.1 -1.7 -0.7 -1.0
Commuting to job workplace: Walk 2.5 2.7 7.4 -0.3 -2.3 -1.2 -1.6 -2.0 -0.1 -1.9 -2.7 -1.6 -2.7 -1.6 0.9 -1.1 -1.9 -1.9 -1.8 -1.7 -1.4 -1.3 -1.0 -0.7 -1.3 -1.7
Eye problems/disorders: Cataract 0.7 0.9 2.4 -0.2 1.3 0.6 0.6 1.1 0.4 0.3 1.5 1.1 1.0 1.1 -0.5 0.8 1.3 1.2 1.0 1.3 0.3 -0.1 1.5 0.9 0.5 0.6
Mouth/teeth dental problems: Mouth ulcers 1.9 3.0 7.3 -1.1 -2.7 -2.0 -1.9 -2.1 -0.7 -2.5 -1.6 -1.7 -0.7 -1.1 1.9 -1.1 -2.0 -1.9 -2.1 -1.7 -1.7 -2.1 -1.7 -1.7 -0.7 -1.1
Medication for cholesterol 2.0 3.1 5.4 2.1 1.7 1.9 1.2 2.0 1.9 -1.0 1.6 1.0 1.3 1.2 -1.6 1.8 1.8 1.7 1.8 1.7 1.9 1.9 2.1 2.1 2.3 2.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 2.6 -0.0 0.6 0.6 1.1 0.5 0.1 -1.0 0.9 0.8 1.6 0.2 -1.2 0.8 0.5 0.8 0.3 0.9 1.0 0.2 0.2 0.9 0.8 0.3
Back pain experienced in last month 1.0 1.5 3.2 0.7 1.8 1.1 1.1 1.6 1.1 0.7 1.5 1.0 -0.4 0.5 -0.9 1.6 1.6 1.6 1.3 1.5 1.1 1.0 1.0 1.2 0.9 1.6
Mineral and other dietary supplements 1.8 2.5 4.6 -1.7 -2.1 -1.6 -1.1 -1.9 0.5 -2.1 -1.7 -1.4 -0.8 -0.7 1.4 -1.5 -2.0 -1.9 -1.9 -1.8 -1.1 -0.9 -2.0 -1.0 -2.0 -1.1
Breast cancer (self-reported) 0.3 0.4 1.8 0.1 0.8 -0.3 0.2 0.8 -0.1 0.3 1.1 1.3 1.0 0.8 0.2 0.7 0.7 0.7 0.7 0.7 0.1 -0.2 -0.0 0.1 0.3 0.4
Asthma (self-reported) 1.0 2.0 8.8 0.4 -0.7 -1.9 -2.6 -0.8 -0.8 0.1 -0.9 -1.7 -1.2 -1.2 2.1 -1.5 -0.4 -0.6 -0.4 -0.4 -2.2 -3.0 -0.3 -0.6 -1.0 -2.1
Osteoporosis (self-reported) 1.2 1.5 3.8 2.0 1.0 1.5 1.9 0.9 0.3 0.8 0.8 1.1 1.1 1.2 -1.9 0.7 0.9 1.0 1.0 1.1 1.4 0.9 1.2 1.5 1.3 0.9
Osteoarthritis (self-reported) 0.4 0.5 2.4 1.0 0.2 0.8 0.5 0.6 -0.4 0.6 0.4 1.2 -1.1 1.6 0.1 0.1 0.5 0.2 0.3 0.2 0.4 0.4 1.4 0.2 -0.0 0.5
Medication: Aspirin 0.5 0.7 3.0 0.8 0.5 -0.5 -1.7 0.5 0.1 1.0 0.2 -0.3 -0.4 -1.0 1.7 1.7 0.7 0.5 0.6 0.6 -0.3 -0.5 0.3 0.6 -0.6 -0.2
Medication: Gliclazide 0.5 0.6 5.8 -0.6 -0.2 0.9 0.7 -0.7 1.0 0.2 0.3 -0.9 1.2 2.4 0.2 0.6 -0.6 -0.7 -0.9 -0.4 -0.2 0.3 0.2 -0.2 -0.1 0.6
Illnesses of father: None of the above (group 1) 0.2 0.2 1.9 0.5 0.0 0.2 0.6 0.1 1.4 -0.6 0.1 1.1 0.1 0.3 -0.3 -0.2 0.0 -0.0 -0.1 0.1 0.3 0.5 0.2 0.4 -0.2 0.7
Smoking status: Current 0.7 1.2 2.9 0.8 1.3 -0.2 -1.2 1.5 1.4 -0.8 1.0 1.4 0.9 -0.5 0.4 0.4 1.6 1.5 1.2 1.7 0.1 -0.2 1.6 1.3 -0.2 -0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 7.7 16.3 23.1 3.5 4.6 4.7 3.7 4.8 2.3 1.8 4.1 4.0 1.9 3.0 -4.2 4.0 4.4 4.5 4.4 4.4 4.8 4.2 3.8 4.1 4.8 4.7
Whole body water mass 0.1 0.6 2.4 1.3 -0.2 -0.0 1.4 -0.4 1.0 1.4 0.4 0.5 1.5 0.8 -0.7 0.6 -0.5 -0.1 -0.2 -0.2 0.4 0.4 -0.6 -0.4 0.9 1.0
Leg predicted mass (right) 0.1 0.4 2.0 1.3 -0.4 -0.7 0.2 -0.5 0.7 1.4 0.1 -0.1 1.3 0.3 -0.1 0.0 -0.5 -0.3 -0.3 -0.3 -0.2 -0.5 -0.7 -0.6 0.7 0.2
Arm fat mass (left) 0.9 3.8 13.2 -0.7 -1.5 -2.3 -1.4 -1.8 -3.6 1.8 -1.4 -1.4 -2.4 -1.1 1.8 -2.1 -1.6 -1.6 -1.4 -1.9 -2.2 -2.0 -1.3 -3.0 -1.6 -2.3
Number of self-reported non-cancer illnesses 1.0 1.7 6.3 -0.7 -0.6 -1.7 -1.8 -0.5 0.0 0.5 -1.0 0.1 -2.3 -2.2 2.5 -0.2 -0.2 -0.4 -0.3 -0.3 -1.9 -1.9 -1.0 0.2 -2.1 -1.0
Average weekly champagne plus white wine intake 1.6 2.1 5.0 -1.0 -1.8 -1.3 -1.4 -1.6 -0.5 -1.5 -2.0 -2.1 -2.0 -0.8 0.7 -1.0 -1.6 -1.8 -1.4 -1.4 -1.8 -1.6 -1.1 -0.2 -0.5 -2.2
Miserableness 0.6 1.0 6.4 -0.0 -0.2 -0.8 -1.2 0.0 2.5 -2.2 -0.0 -0.9 1.1 -0.5 1.0 0.3 0.2 0.2 -0.1 0.5 -0.6 -1.3 0.7 1.6 -0.3 -0.2
Guilty feelings 0.6 0.9 8.2 0.6 -0.3 0.1 -0.1 -0.2 2.5 -2.9 -0.3 0.3 -0.4 -0.4 -0.4 0.0 -0.2 0.0 -0.3 0.2 0.6 0.6 -0.7 1.7 0.6 0.9
Wears glasses or contact lenses 0.3 0.4 2.3 0.1 0.2 0.8 0.0 0.8 0.3 -0.7 0.1 -0.2 0.3 -0.0 -0.5 0.7 0.6 0.6 0.6 0.5 1.1 1.5 0.1 0.6 0.4 0.7
Ever taken oral contraceptive pill 1.1 1.3 3.3 0.4 0.9 1.3 0.9 1.1 1.8 -1.0 0.9 1.5 1.0 0.9 -1.1 1.2 0.8 0.9 0.8 1.0 1.5 1.8 0.6 1.3 0.7 1.2
Hearing aid user 1.0 1.1 5.7 -1.5 -1.2 -1.0 0.2 -1.0 -0.8 -2.4 -1.4 -0.9 -0.7 -0.9 -0.3 -0.9 -1.3 -1.1 -1.3 -1.0 0.1 0.3 -1.6 -0.2 0.0 -0.8
Mother’s age at death 0.5 0.6 4.5 0.0 -1.0 0.6 0.6 -0.9 0.0 -0.3 -0.9 -0.5 -2.1 1.0 -0.7 -0.3 -0.9 -0.9 -0.8 -0.8 -0.0 0.4 -1.0 0.2 0.9 0.4
Financial situation satisfaction 1.0 1.2 4.0 -0.5 0.9 0.8 1.9 0.7 0.3 -0.9 1.2 2.0 0.3 1.5 -1.6 1.1 0.7 0.8 0.6 0.9 1.6 0.8 1.1 1.3 0.8 0.8
Tinnitus: Yes, now most or all of the time 3.9 4.6 7.0 -2.2 -2.3 -1.9 -1.5 -2.1 -2.0 -1.9 -2.5 -2.7 -1.9 -1.0 2.1 -2.2 -2.2 -2.3 -2.4 -2.4 -2.3 -1.5 -2.4 -2.4 -2.2 -2.0
Commuting to job workplace: Public transport 0.9 1.1 4.1 -1.3 -1.3 -1.3 -0.5 -0.9 -1.1 -2.0 -1.4 -1.0 -1.6 -0.4 0.1 -0.7 -0.9 -0.9 -1.0 -1.0 -0.8 -0.6 -0.4 -0.9 -0.2 -1.6
Eye problems/disorders: Glaucoma 2.2 2.6 7.0 -0.9 -1.6 -1.7 -1.5 -1.7 -2.6 0.4 -1.5 -2.0 -0.5 -1.1 1.6 -2.0 -1.6 -1.6 -1.4 -1.7 -1.9 -1.7 -1.2 -1.7 -1.5 -2.1
Medication: Blood pressure 2.4 4.6 6.9 -2.1 -2.1 -2.1 -2.0 -2.4 -2.0 2.1 -1.8 -1.8 -1.6 -1.6 2.4 -1.7 -2.1 -2.0 -2.2 -2.1 -2.4 -2.3 -2.5 -2.6 -2.3 -2.4
Pain type(s) experienced in last month: Hip pain 3.0 3.7 7.8 0.4 2.8 0.9 0.6 2.7 2.0 -0.0 2.7 2.6 0.7 0.1 -0.4 2.5 2.6 2.5 2.3 2.4 1.5 1.1 1.9 2.7 1.0 2.3
Supplements: Fish oil (including cod liver oil) 0.7 0.9 2.1 0.7 1.4 0.9 0.5 1.2 -0.9 1.4 1.1 -0.1 1.3 -0.6 -0.9 1.0 1.2 1.2 1.1 1.1 0.5 0.5 0.7 0.2 1.2 0.4
High cholesterol (Self-reported) 0.2 0.3 0.7 -0.7 -0.6 -0.5 -0.0 -0.7 -0.8 0.6 -0.5 -0.3 -0.6 -0.4 0.7 0.0 -0.5 -0.6 -0.6 -0.5 -0.5 -0.5 -0.4 -0.5 -0.8 -0.5
Medication: Bendroflumethiazide 4.5 6.9 11.9 -3.5 -2.9 -2.6 -2.1 -3.0 -1.9 -0.6 -2.6 -1.5 -2.0 -2.2 2.7 -2.6 -2.7 -2.7 -3.0 -2.7 -2.9 -2.3 -3.1 -3.2 -3.2 -2.8
Medication: Paracetamol 0.7 1.1 2.7 -1.3 1.2 -0.8 -1.6 1.3 0.2 -1.3 0.9 -0.1 0.5 -1.7 1.5 0.6 1.4 1.2 1.0 1.3 -0.9 -1.5 0.1 0.6 -0.5 -0.7
Medication: Lisinopril 1.8 2.3 4.9 -1.4 -1.9 -1.6 -1.3 -1.7 -0.8 -0.8 -1.5 -1.2 -1.3 -0.6 1.8 -1.2 -1.6 -1.7 -1.7 -1.7 -1.8 -1.3 -1.5 -2.2 -1.4 -1.5
Medication: Atorvastatin 0.2 0.3 2.1 -1.4 -0.5 -0.5 -0.1 -0.2 0.3 -0.7 -0.2 0.7 -0.7 -0.5 0.0 0.0 -0.3 -0.2 -0.5 -0.1 0.4 0.1 -0.9 -0.1 -0.3 -0.3
Illnesses of father: High blood pressure 1.5 1.8 3.9 -0.8 -1.4 -1.4 -1.0 -1.4 -1.6 -0.4 -1.4 -1.4 -0.9 -1.5 1.1 -1.5 -1.4 -1.2 -1.3 -1.5 -1.2 -1.3 -1.9 -2.0 -1.3 -1.2
Alcohol drinker status: Never 2.7 3.2 7.8 -1.8 -2.0 -1.4 -0.7 -2.3 -1.4 1.0 -2.1 -1.9 -0.6 -2.1 1.2 -1.8 -2.2 -2.2 -2.1 -2.2 -1.5 -1.1 -2.8 -1.7 -1.6 -1.3
Ever smoked 1.6 2.8 9.4 2.7 1.4 0.1 -1.4 1.6 2.9 1.3 1.4 1.0 0.9 -0.7 0.0 1.9 1.9 1.9 1.5 2.3 0.4 -0.8 3.1 2.3 1.3 0.3
Basal metabolic rate 0.1 0.4 2.0 0.9 -0.5 -0.4 1.1 -0.6 0.3 1.4 0.1 0.2 1.0 0.5 -0.5 0.2 -0.7 -0.4 -0.4 -0.5 0.1 0.1 -0.8 -0.8 0.6 0.5
Leg fat percentage (left) 1.7 6.1 21.1 -2.2 -1.7 -2.5 -1.5 -2.2 -4.6 1.0 -2.1 -1.4 -4.6 -1.2 2.1 -2.3 -1.9 -2.1 -1.7 -2.4 -2.8 -2.2 -1.6 -3.3 -2.5 -3.0
Arm fat-free mass (left) 0.1 0.4 2.3 0.8 -0.3 -0.3 1.4 -0.6 0.0 1.5 0.3 0.7 0.6 0.8 -0.6 0.3 -0.6 -0.3 -0.3 -0.4 0.1 0.2 -0.8 -0.9 0.6 0.5
Number of operations (self-reported) 0.1 0.2 0.8 0.3 0.1 0.1 -0.1 0.3 0.1 0.7 0.1 0.4 -0.9 0.4 0.3 0.4 0.4 0.4 0.4 0.3 -0.0 -0.5 0.8 0.6 0.3 0.1
Average weekly beer plus cider intake 1.2 1.8 5.9 2.1 1.0 0.7 1.1 1.1 2.2 -0.3 1.2 0.4 2.4 0.1 -0.7 1.1 0.9 1.1 0.8 1.1 1.7 1.5 1.5 1.5 1.1 2.0
Irritability 0.6 0.9 2.8 -0.1 -0.1 -1.3 -1.5 -0.3 1.5 -1.7 -0.2 0.1 -1.2 -1.6 1.6 0.6 -0.1 -0.1 -0.6 0.2 -0.9 -1.6 -0.5 0.8 -0.4 -0.6
Risk taking 2.7 4.0 6.0 2.1 2.2 1.8 1.8 2.2 0.8 1.8 2.2 1.3 0.9 2.0 -2.3 1.9 2.3 2.4 2.5 2.3 2.0 1.3 2.2 2.1 2.4 1.6
Ever had prostate specific antigen (PSA) test 0.4 0.5 1.9 -1.1 -0.8 0.2 0.2 -0.8 -0.4 -0.2 -0.8 0.3 -0.9 0.0 0.4 0.0 -0.8 -0.9 -0.8 -1.0 -0.3 0.3 -1.4 -0.9 -0.8 0.1
Fractured/broken bones in last 5 years 0.6 0.7 3.1 0.4 -0.5 -1.2 -1.2 -0.2 -1.8 -0.1 -0.3 0.4 -1.8 -0.3 0.5 -0.7 -0.2 -0.3 -0.0 -0.2 -0.8 -0.9 -1.3 -0.6 0.2 -1.6
Age started oral contraceptive pill 0.7 0.9 3.2 0.1 -0.7 -1.1 -0.7 -0.9 -1.8 0.7 -0.8 0.2 -1.2 0.2 0.8 -1.1 -0.8 -0.9 -0.5 -1.0 -1.4 -1.1 -0.9 -1.2 -0.5 -1.5
Diastolic blood pressure, automated reading 8.7 27.1 41.4 -4.5 -6.2 -5.0 -3.1 -6.1 -5.4 -1.8 -6.4 -5.0 -4.9 -4.3 4.1 -5.3 -6.0 -6.1 -5.8 -6.3 -4.8 -4.0 -5.5 -6.3 -5.3 -4.8
Ever depressed for a whole week 0.4 0.4 3.2 -1.0 -0.3 -0.3 -0.1 -0.2 -0.7 -1.8 -0.6 0.3 -1.5 0.8 0.2 -0.6 -0.1 -0.2 -0.3 -0.1 -0.5 -0.3 -0.1 -0.2 0.0 -0.8
Unable to work because of sickness or disability 1.0 1.3 3.6 -0.3 1.2 1.6 1.7 1.1 -1.0 -1.5 1.1 0.8 -0.4 0.8 -1.9 0.8 1.0 1.1 0.8 1.1 1.5 1.6 0.3 1.0 1.5 0.4
Commuting to job workplace: Cycle 0.3 0.4 2.1 -1.4 -0.6 -0.2 0.2 -0.3 -0.8 -0.5 -0.3 -0.3 0.2 -0.6 -0.4 -0.7 -0.4 -0.4 -0.3 -0.5 0.2 0.4 -0.7 -1.4 -0.3 -0.6
Myopia 1.6 2.4 6.3 -0.9 -1.1 -1.8 -2.2 -1.3 0.1 1.1 -1.4 -2.1 -0.9 -2.5 2.3 -0.8 -1.1 -1.0 -1.0 -1.0 -2.0 -2.3 -2.0 -1.0 -1.5 -1.1
Vascular/heart problems diagnosed by doctor 5.9 16.1 27.2 3.2 4.2 4.4 4.0 4.6 2.8 -0.3 4.2 3.4 3.2 3.8 -4.6 3.6 4.2 4.1 4.3 4.1 4.4 4.1 5.2 4.3 4.5 4.1
Cholesterol lowering medication 0.3 0.4 3.6 -0.7 0.0 0.1 -0.1 0.0 -1.9 1.7 0.4 0.6 -0.4 0.9 -0.0 0.1 0.1 0.1 0.1 0.1 0.1 -0.3 0.4 -0.6 -0.1 -0.9
Medication: Omeprazole (e.g. Zanprol) 2.6 3.2 6.2 0.3 2.2 1.8 1.1 2.3 1.7 0.6 1.9 2.5 0.3 1.5 -1.2 2.2 2.3 2.2 2.0 2.2 1.6 1.5 1.8 2.0 1.6 1.8
Pain experienced in last month 0.3 0.4 2.6 1.6 -0.6 0.8 0.5 -0.6 0.4 0.4 -0.3 -0.2 0.3 0.9 -0.9 0.3 -0.7 -0.4 -0.3 -0.5 0.6 0.9 -0.1 -0.3 0.7 0.8
Supplements: Calcium 1.3 1.5 4.5 0.8 1.1 0.8 0.8 0.9 0.5 1.4 1.6 1.7 1.4 2.1 -0.5 1.4 1.1 1.3 1.0 1.2 0.6 0.4 1.5 1.0 1.4 1.2
Basal cell carcinoma (self-reported) 0.9 1.1 3.1 1.4 0.7 0.7 0.9 1.1 0.9 0.5 1.1 1.2 1.5 0.9 -0.7 0.7 0.9 1.1 1.2 0.8 1.3 0.9 1.2 0.6 1.0 1.8
Heart attack/myocardial infarction (self-reported) 0.7 0.8 3.0 -0.1 -0.5 -1.1 -1.7 -0.7 1.2 -0.0 -0.7 -1.7 0.1 -1.0 1.2 0.4 -0.3 -0.5 -0.4 -0.1 -1.3 -1.6 -0.8 0.2 -0.6 -1.1
Deep venous thrombosis (DVT) (self-reported) 0.8 1.0 6.1 0.1 -0.4 -0.2 1.4 -0.9 -2.5 2.2 -0.6 -0.0 -0.9 -0.4 -0.7 -0.5 -0.9 -1.0 -0.7 -1.1 -0.2 0.0 -0.0 -1.2 -0.6 -0.4
Heart disease (siblings) 1.2 1.5 4.0 1.3 2.0 0.1 -1.6 1.6 0.9 0.9 1.7 -0.1 0.5 -0.3 0.5 1.3 1.8 1.8 1.5 1.9 0.5 -0.7 0.7 1.7 0.6 -0.1
Alcohol drinker status: Previous 0.4 0.5 1.5 0.4 -1.1 -0.5 -0.5 -0.7 -0.5 -1.0 -1.1 -1.2 -0.6 0.2 0.7 -0.9 -0.7 -0.8 -0.4 -0.8 -0.5 -0.1 0.3 -0.6 -0.5 -0.8
Pack years of smoking 3.5 5.1 7.5 1.8 2.6 2.7 2.2 2.6 1.3 1.4 2.5 2.7 1.4 2.0 -2.2 2.0 2.6 2.5 2.7 2.5 2.1 2.3 2.5 2.3 2.0 2.4
Impedance of whole body 0.8 3.9 11.2 -1.1 1.6 3.1 2.6 1.8 1.2 -2.6 1.6 1.6 1.6 2.0 -2.7 1.4 1.5 1.4 1.3 1.5 2.6 3.4 1.7 1.9 1.1 1.9
Leg fat mass (left) 1.1 4.2 13.2 -1.4 -1.5 -2.4 -1.2 -2.0 -3.6 1.5 -1.6 -1.3 -3.0 -1.2 1.7 -1.9 -1.8 -1.8 -1.5 -2.1 -2.4 -1.9 -1.7 -3.1 -1.9 -2.4
Arm predicted mass (left) 0.1 0.5 3.2 0.8 -0.3 -0.0 1.8 -0.5 0.0 1.3 0.3 1.0 0.7 0.9 -1.0 0.4 -0.6 -0.3 -0.3 -0.4 0.4 0.6 -0.6 -0.8 0.8 0.7