Best TWAS P=1.47e-08 · Best GWAS P=2.93e-07 conditioned to 0.26
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | PIGV | 0.09 | 0.07 | enet | 25 | 0.13 | 3.4e-08 | 4.5 | -5.5 | 3.0e-08 | -0.66 | 0.16 | 0.80 | TRUE |
| 2 | GTEx | Thyroid | ZDHHC18 | 0.11 | 0.10 | lasso | 4 | 0.13 | 4.2e-10 | 5.1 | 5.3 | 1.3e-07 | 0.96 | 0.01 | 0.98 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | CD164L2 | 0.16 | 0.13 | bslmm | 220 | 0.16 | 2.4e-20 | -4.5 | -5.4 | 5.3e-08 | -0.09 | 0.09 | 0.89 | FALSE |
| 4 | YFS | Blood | ZDHHC18 | 0.08 | 0.11 | bslmm | 286 | 0.11 | 2.1e-33 | 5.1 | 5.1 | 3.0e-07 | 0.97 | 0.01 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PIGV | 0.02 | 0.02 | lasso | 10 | 0.03 | 1.3e-06 | 5.1 | -5.2 | 2.0e-07 | -0.92 | 0.01 | 0.98 | FALSE |
| 6 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CD164L2 | 0.04 | 0.06 | blup | 36 | 0.06 | 9.2e-08 | -4.6 | -5.2 | 1.9e-07 | -0.09 | 0.02 | 0.96 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | FCN3 | 0.03 | 0.03 | blup | 35 | 0.02 | 8.0e-03 | -4.5 | 5.7 | 1.5e-08 | 0.12 | 0.02 | 0.54 | TRUE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | PIGV | 0.04 | 0.04 | lasso | 4 | 0.04 | 2.1e-04 | 5.1 | -5.1 | 2.9e-07 | -1.00 | 0.00 | 0.97 | FALSE |