[Hub]/) : Traits : Hypertension (Self-reported) : ← →

chr7:73,425,238-75,714,883

Best TWAS P=4.34e-09 · Best GWAS P=9.03e-09 conditioned to 0.34

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous AC004166.6 0.09 0.08 lasso 2 0.07 3.9e-06 5.7 5.5 3.1e-08 0.85 0.01 0.99 FALSE
2 GTEx Adipose Subcutaneous STAG3L1 0.30 0.24 enet 24 0.27 2.4e-22 -4.5 -5.3 1.2e-07 -0.12 0.00 0.97 TRUE
3 GTEx Adrenal Gland STAG3L2 0.14 0.07 enet 3 0.11 1.2e-04 5.2 -5.3 1.1e-07 -0.92 0.02 0.77 FALSE
4 GTEx Cells EBV-transformed lymphocytes PMS2P5 0.16 0.06 lasso 3 0.04 1.7e-02 5.7 -5.5 3.9e-08 -0.82 0.01 0.76 FALSE
5 GTEx Esophagus Gastroesophageal Junction PMS2P5 0.23 0.19 lasso 2 0.18 5.4e-07 5.7 -5.9 4.3e-09 -0.77 0.01 0.98 TRUE
6 GTEx Esophagus Mucosa PMS2P5 0.14 0.03 lasso 4 0.04 1.7e-03 5.7 -5.8 5.6e-09 -0.79 0.01 0.87 FALSE
7 GTEx Esophagus Muscularis STAG3L2 0.23 0.09 enet 33 0.15 1.9e-09 3.6 -5.2 1.9e-07 -0.76 0.03 0.96 FALSE
8 GTEx Heart Atrial Appendage PMS2P5 0.12 0.03 lasso 5 0.07 3.8e-04 5.7 -5.7 1.4e-08 -0.75 0.01 0.60 FALSE
9 GTEx Nerve Tibial STAG3L2 0.36 0.09 enet 13 0.24 9.5e-17 3.6 -5.4 5.1e-08 -0.75 0.02 0.97 FALSE
10 GTEx Skin Sun Exposed Lower leg STAG3L2 0.15 0.05 enet 8 0.08 2.8e-07 3.6 -5.3 1.2e-07 -0.72 0.06 0.86 FALSE
11 GTEx Testis PMS2P5 0.22 0.13 lasso 2 0.13 3.1e-06 5.7 -5.5 4.1e-08 -0.75 0.01 0.96 FALSE
12 GTEx Testis STAG3L2 0.26 0.13 lasso 4 0.22 4.0e-10 3.2 -5.2 2.6e-07 -0.86 0.03 0.97 FALSE
13 GTEx Thyroid GTF2IRD2B 0.03 0.04 lasso 1 0.03 1.9e-03 5.6 5.6 1.9e-08 0.96 0.01 0.82 FALSE
14 METSIM Adipose NCF1 0.05 0.03 blup 130 0.04 3.9e-07 5.7 5.4 6.1e-08 0.71 0.01 0.99 FALSE