Best TWAS P=7.29e-10 · Best GWAS P=3.89e-09 conditioned to 0.0683
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Caudate basal ganglia | BICC1 | 0.27 | 0.16 | lasso | 1 | 0.16 | 2.7e-05 | -5.8 | -5.8 | 7.3e-09 | 0.99 | 0.03 | 0.90 | FALSE |
2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | BICC1 | 0.07 | 0.00 | blup | 143 | 0.02 | 1.5e-02 | -5.8 | -6.2 | 7.3e-10 | 0.77 | 0.02 | 0.52 | TRUE |