Best TWAS P=6.22e-12 · Best GWAS P=6.27e-17 conditioned to 4.9e-12
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | NSUN6 | 0.18 | 0.11 | lasso | 8 | 0.10 | 4.9e-08 | -3.7 | 5.7 | 1.6e-08 | -0.25 | 1.00 | 0 | TRUE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CACNB2 | 0.05 | 0.05 | enet | 4 | 0.04 | 8.8e-06 | 5.8 | 6.9 | 6.2e-12 | -0.11 | 0.99 | 0 | TRUE |