Best TWAS P=6.57e-10 · Best GWAS P=3.7e-09 conditioned to 0.378
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Coronary | RP11-810M2.2 | 0.30 | 0.02 | lasso | 4 | 0.02 | 0.085 | 5.7 | 6.2 | 6.6e-10 | 0.89 | 0.02 | 0.80 | TRUE |
2 | GTEx | Muscle Skeletal | ZZEF1 | 0.11 | 0.01 | lasso | 3 | 0.01 | 0.019 | 5.7 | 5.6 | 1.6e-08 | 0.97 | 0.01 | 0.97 | FALSE |