Best TWAS P=3.6e-09 · Best GWAS P=2.53e-10 conditioned to 1.65e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | AP001266.1 | 0.11 | 0.02 | enet | 9 | 0.09 | 2.8e-07 | 4.1 | 5.4 | 7.5e-08 | -0.41 | 0.52 | 0.32 | FALSE |
| 2 | GTEx | Artery Tibial | AP5B1 | 0.11 | 0.02 | enet | 16 | 0.07 | 1.8e-06 | 2.4 | 5.4 | 8.4e-08 | -0.41 | 0.44 | 0.42 | FALSE |
| 3 | YFS | Blood | EFEMP2 | 0.12 | 0.07 | bslmm | 348 | 0.13 | 4.3e-41 | -3.4 | -5.9 | 3.6e-09 | 0.40 | 0.80 | 0.19 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | DKFZp761E198 | 0.06 | 0.05 | blup | 39 | 0.05 | 3.0e-05 | 4.1 | 5.6 | 2.2e-08 | -0.56 | 0.18 | 0.58 | FALSE |