[Hub]/) : Traits : Asthma (self-reported) :

chr22:41,071,659-42,685,537

Best TWAS P=3.14e-08 · Best GWAS P=7.96e-08 conditioned to 0.487

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CSDC2 0.20 0.30 lasso 5 0.32 2.1e-40 4.8 5.2 2.1e-07 0.95 0.07 0.93 FALSE
2 GTEx Artery Aorta ACO2 0.08 0.08 lasso 5 0.06 2.8e-04 5.4 5.4 8.1e-08 0.98 0.04 0.92 FALSE
3 GTEx Brain Cerebellar Hemisphere POLR3H 0.10 0.08 lasso 7 0.08 4.9e-03 5.2 5.2 2.1e-07 0.96 0.05 0.76 FALSE
4 GTEx Brain Cortex POLR3H 0.27 0.21 lasso 8 0.18 8.5e-06 5.2 5.2 2.6e-07 0.97 0.05 0.94 FALSE
5 GTEx Brain Cortex CSDC2 0.31 0.32 lasso 5 0.28 1.8e-08 4.7 5.2 2.5e-07 0.95 0.13 0.87 FALSE
6 GTEx Brain Frontal Cortex BA9 POLR3H 0.13 0.09 lasso 7 0.04 3.4e-02 5.3 5.2 1.9e-07 0.97 0.05 0.78 FALSE
7 GTEx Brain Frontal Cortex BA9 CSDC2 0.25 0.23 lasso 8 0.24 3.8e-07 5.3 5.2 1.8e-07 0.99 0.05 0.94 FALSE
8 GTEx Brain Hippocampus POLR3H 0.16 0.11 lasso 14 0.05 2.4e-02 5.3 5.2 1.7e-07 0.98 0.06 0.72 FALSE
9 GTEx Brain Nucleus accumbens basal ganglia CSDC2 0.25 0.28 lasso 2 0.29 1.8e-08 5.2 5.2 2.2e-07 0.96 0.08 0.91 FALSE
10 GTEx Cells EBV-transformed lymphocytes PMM1 0.20 0.16 lasso 7 0.14 1.9e-05 5.4 -5.4 5.7e-08 -0.98 0.05 0.94 FALSE
11 GTEx Cells EBV-transformed lymphocytes TEF 0.23 0.13 lasso 7 0.16 6.9e-06 5.4 5.3 1.0e-07 0.99 0.04 0.96 FALSE
12 GTEx Esophagus Muscularis PMM1 0.07 0.05 lasso 5 0.05 6.8e-04 4.8 -5.1 3.1e-07 -0.96 0.14 0.83 FALSE
13 The Cancer Genome Atlas Bladder Urothelial Carcinoma PMM1 0.04 0.03 lasso 6 0.02 6.1e-03 5.2 -5.2 2.1e-07 -0.96 0.01 0.75 FALSE
14 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ACO2 0.03 0.01 blup 41 0.04 3.9e-03 -3.8 5.5 4.6e-08 0.95 0.02 0.56 FALSE
15 The Cancer Genome Atlas Lung Adenocarcinoma PMM1 0.02 0.03 lasso 5 0.02 1.1e-03 5.1 -5.1 2.9e-07 -0.96 0.01 0.89 FALSE
16 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PHF5A 0.03 0.00 blup 30 0.01 2.9e-02 5.3 5.5 3.1e-08 0.92 0.01 0.56 TRUE
17 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TOB2 0.03 0.00 blup 28 0.02 3.4e-03 5.1 5.3 1.2e-07 0.96 0.01 0.60 FALSE
18 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma PMM1 0.05 0.06 blup 18 0.06 4.1e-05 4.8 -5.1 3.0e-07 -0.95 0.02 0.97 FALSE
19 The Cancer Genome Atlas Testicular Germ Cell Tumors POLR3H 0.10 0.02 blup 23 0.06 3.4e-03 5.2 -5.2 2.1e-07 -0.92 0.01 0.78 FALSE