Best TWAS P=9.64e-09 · Best GWAS P=6.93e-08 conditioned to 0.381
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | RUVBL1 | 0.31 | 0.30 | lasso | 12 | 0.30 | 1.2e-13 | -5.1 | -5.1 | 2.9e-07 | 0.98 | 0.03 | 0.97 | FALSE |
| 2 | The Cancer Genome Atlas | Glioblastoma Multiforme | EEFSEC | 0.09 | 0.07 | lasso | 10 | 0.05 | 1.7e-02 | -5.1 | 5.3 | 1.4e-07 | -0.98 | 0.02 | 0.78 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | EEFSEC | 0.07 | 0.05 | blup | 115 | 0.07 | 1.6e-08 | -4.8 | 5.1 | 3.0e-07 | -0.78 | 0.22 | 0.78 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | EEFSEC | 0.08 | 0.03 | blup | 116 | 0.04 | 1.8e-04 | -5.1 | 5.7 | 9.6e-09 | -0.86 | 0.03 | 0.96 | TRUE |