[Hub]/) : Traits : Diabetes (self-reported) :

chr2:26,883,355-28,402,863

Best TWAS P=1.36e-09 · Best GWAS P=2.17e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex IFT172 0.06 0.09 enet 16 0.09 3.9e-11 4.2 5.3 1.2e-07 -0.75 0.43 0.57 FALSE
2 GTEx Adipose Subcutaneous AC074117.10 0.06 0.04 lasso 5 0.02 4.8e-03 5.3 -5.7 1.2e-08 0.65 0.46 0.25 FALSE
3 GTEx Cells Transformed fibroblasts AC074117.10 0.21 0.19 enet 23 0.18 1.6e-13 5.3 -5.7 1.1e-08 0.66 0.47 0.53 FALSE
4 GTEx Esophagus Mucosa AC074117.10 0.12 0.14 lasso 8 0.14 2.1e-09 5.3 -5.4 6.1e-08 0.74 0.84 0.16 FALSE
5 GTEx Esophagus Muscularis NRBP1 0.07 0.04 lasso 6 0.04 1.3e-03 5.3 -5.4 5.7e-08 0.82 0.02 0.96 FALSE
6 GTEx Esophagus Muscularis AC074117.10 0.17 0.14 enet 5 0.09 6.6e-06 5.3 -5.4 6.1e-08 0.65 0.54 0.45 FALSE
7 GTEx Nerve Tibial NRBP1 0.06 0.00 enet 9 0.02 2.0e-02 5.3 -5.3 1.5e-07 0.61 0.34 0.53 FALSE
8 GTEx Ovary AC074117.10 0.16 0.04 enet 9 0.05 2.0e-02 4.4 -5.2 2.2e-07 0.77 0.05 0.76 FALSE
9 GTEx Testis NRBP1 0.16 0.09 lasso 3 0.06 1.8e-03 5.3 -5.9 4.2e-09 0.80 0.03 0.96 FALSE
10 GTEx Testis AC074117.10 0.14 0.08 lasso 6 0.12 4.5e-06 4.5 -5.8 7.7e-09 0.85 0.04 0.96 FALSE
11 METSIM Adipose NRBP1 0.06 0.09 lasso 3 0.08 1.6e-12 5.3 -5.5 4.4e-08 0.67 0.78 0.22 FALSE
12 ROSMAP Brain Pre-frontal Cortex FTH1P3 0.04 0.01 bslmm 280 0.02 2.8e-03 5.3 -5.4 7.9e-08 0.65 0.04 0.71 FALSE
13 YFS Blood NRBP1 0.01 0.01 lasso 6 0.01 9.1e-06 4.5 -5.1 3.0e-07 0.61 0.93 0.06 FALSE
14 The Cancer Genome Atlas Glioblastoma Multiforme NRBP1 0.15 0.10 lasso 2 0.10 5.8e-04 5.3 -5.3 1.1e-07 0.67 0.00 0.68 FALSE
15 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma FNDC4 0.13 0.06 lasso 2 0.05 1.1e-03 -6.3 6.1 1.4e-09 -0.99 0.00 0.94 TRUE