[Hub]/) : Traits : Glaucoma (self-reported) : →

chr1:164,933,115-166,462,417

Best TWAS P=2.11e-27 · Best GWAS P=2.24e-29 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta ALDH9A1 0.17 0.17 lasso 3 0.12 2.1e-07 5.0 -5.9 3.4e-09 -0.50 0.89 0.09 FALSE
2 GTEx Artery Tibial ALDH9A1 0.36 0.31 enet 28 0.35 5.2e-28 5.0 -6.0 1.6e-09 -0.44 1.00 0.00 FALSE
3 GTEx Artery Tibial TMCO1 0.15 0.02 lasso 4 0.01 4.5e-02 11.1 -10.8 2.1e-27 -0.97 0.01 0.99 TRUE
4 GTEx Cells Transformed fibroblasts ALDH9A1 0.20 0.06 enet 51 0.14 5.1e-11 4.0 -5.3 1.4e-07 -0.46 0.33 0.60 FALSE
5 GTEx Colon Sigmoid ALDH9A1 0.41 0.18 lasso 8 0.26 7.4e-10 5.0 -6.1 1.1e-09 -0.53 0.39 0.59 FALSE
6 GTEx Lung ALDH9A1 0.19 0.10 enet 24 0.17 6.5e-13 5.0 -6.1 1.2e-09 -0.52 0.98 0.02 FALSE
7 GTEx Muscle Skeletal Y_RNA 0.11 0.03 enet 22 0.06 1.3e-06 5.1 -5.4 7.1e-08 -0.36 0.78 0.04 FALSE
8 GTEx Nerve Tibial ALDH9A1 0.30 0.35 enet 31 0.34 3.7e-25 5.0 -5.8 6.0e-09 -0.40 1.00 0.00 FALSE
9 GTEx Stomach ALDH9A1 0.30 0.26 lasso 5 0.24 5.4e-12 5.0 -5.2 1.6e-07 -0.43 1.00 0.00 FALSE
10 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ALDH9A1 0.11 0.07 lasso 3 0.04 1.8e-03 5.0 -5.1 3.1e-07 -0.41 0.04 0.12 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma ALDH9A1 0.08 0.03 enet 11 0.07 2.6e-08 5.1 -5.6 1.9e-08 -0.52 0.31 0.51 FALSE
12 The Cancer Genome Atlas Pancreatic Adenocarcinoma ALDH9A1 0.13 0.06 lasso 2 0.07 7.9e-04 5.0 -5.2 2.6e-07 -0.44 0.08 0.23 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma ALDH9A1 0.14 0.09 enet 13 0.09 6.8e-10 5.0 -6.2 4.1e-10 -0.50 1.00 0.00 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma ALDH9A1 0.20 0.06 enet 12 0.13 9.4e-13 5.0 -6.9 3.8e-12 -0.48 1.00 0.00 FALSE