Best TWAS P=2.15e-07 · Best GWAS P=9.98e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | RFTN2 | 0.14 | 0.10 | enet | 11 | 0.13 | 5.3e-11 | 5.3 | 5.2 | 2.2e-07 | 0.91 | 0.01 | 0.98 | FALSE |
2 | GTEx | Spleen | RFTN2 | 0.11 | 0.03 | enet | 26 | 0.05 | 2.4e-02 | 4.6 | 5.1 | 3.0e-07 | 0.88 | 0.06 | 0.53 | FALSE |
3 | GTEx | Thyroid | PLCL1 | 0.04 | 0.01 | lasso | 4 | 0.00 | 2.6e-01 | 4.6 | 5.1 | 2.7e-07 | 0.81 | 0.15 | 0.61 | FALSE |
4 | GTEx | Whole Blood | PLCL1 | 0.08 | 0.08 | enet | 15 | 0.05 | 4.1e-05 | 4.9 | 5.2 | 2.2e-07 | 0.97 | 0.02 | 0.98 | TRUE |