[Hub]/) : Traits : Hayfever/allergic rhinitis (self-reported) :

chr2:102,118,712-103,686,111

Best TWAS P=2.57e-21 · Best GWAS P=3.04e-17 conditioned to 0.0535

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Colon Transverse IL18R1 0.14 0.00 enet 41 0.00 2.1e-01 2.4 5.8 6.0e-09 -0.45 0.06 0.16 FALSE
2 ROSMAP Brain Pre-frontal Cortex IL1RL2 0.08 0.02 enet 33 0.03 2.3e-04 4.0 -5.8 7.1e-09 0.18 0.19 0.06 FALSE
3 The Cancer Genome Atlas Bladder Urothelial Carcinoma IL1RL1 0.04 0.03 lasso 7 0.03 8.1e-04 -8.3 -8.4 4.8e-17 0.90 0.02 0.93 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma IL18R1 0.05 0.01 blup 108 0.03 1.8e-07 -8.2 6.6 5.6e-11 -0.78 0.02 0.98 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma IL1RL1 0.02 0.01 blup 78 0.01 1.5e-03 8.2 -8.2 2.3e-16 0.68 0.03 0.86 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma IL1RL1 0.04 0.04 lasso 8 0.04 1.7e-05 -7.6 -8.9 3.8e-19 0.81 0.11 0.75 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma IL18RAP 0.03 0.02 blup 94 0.02 1.2e-03 -8.2 7.6 2.7e-14 -0.81 0.00 0.93 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma IL1RL1 0.08 0.08 enet 9 0.08 1.2e-09 -7.5 -8.9 8.0e-19 0.61 0.91 0.09 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma IL1RL2 0.04 0.04 enet 5 0.03 1.9e-04 -5.6 -5.7 1.3e-08 0.37 0.06 0.41 FALSE
10 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma IL1RL1 0.18 0.06 blup 78 0.15 3.7e-09 8.2 -9.3 2.0e-20 0.59 0.06 0.94 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma IL1RL1 0.03 0.01 blup 78 0.02 4.7e-03 -7.4 -9.5 2.6e-21 0.76 0.09 0.40 TRUE
12 The Cancer Genome Atlas Pancreatic Adenocarcinoma IL1RL1 0.19 0.05 blup 78 0.10 7.1e-05 8.3 -9.3 2.1e-20 0.84 0.03 0.93 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma IL1RL1 0.05 0.03 enet 6 0.03 9.7e-04 -7.5 -7.7 1.8e-14 0.51 0.64 0.14 FALSE