Best TWAS P=7.3e-15 · Best GWAS P=7.82e-16 conditioned to 0.314
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ZNF259 | 0.08 | 0.03 | enet | 6 | 0.03 | 0.00012 | 6.2 | -7.8 | 7.3e-15 | -0.76 | 0.02 | 0.98 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | PAFAH1B2 | 0.11 | 0.00 | lasso | 3 | 0.00 | 0.13000 | 5.9 | -6.2 | 7.5e-10 | -0.42 | 0.06 | 0.22 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | ZNF259 | 0.04 | 0.03 | lasso | 3 | 0.02 | 0.00084 | 6.4 | -6.5 | 7.4e-11 | -0.48 | 0.19 | 0.08 | FALSE |