[Hub]/) : Traits : Medication: Simvastatin : ← →

chr11:115,953,897-117,745,003

Best TWAS P=7.3e-15 · Best GWAS P=7.82e-16 conditioned to 0.314

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ZNF259	0.08	0.03	enet	6	0.03	0.00012	6.2	-7.8	7.3e-15	-0.76	0.02	0.98	TRUE
2	GTEx	Cells Transformed fibroblasts	PAFAH1B2	0.11	0.00	lasso	3	0.00	0.13000	5.9	-6.2	7.5e-10	-0.42	0.06	0.22	TRUE
3	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ZNF259	0.04	0.03	lasso	3	0.02	0.00084	6.4	-6.5	7.4e-11	-0.48	0.19	0.08	FALSE