TWAS hub - ZNF259

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.080	0.0260	0.00023	0.034	0.030	0.030	0.03	0.028	4.5e-05	0.00012	0.00012	0.00012	0.00020
2	TCGA	Lung Squamous Cell Carcinoma	0.039	0.0227	0.00940	0.033	0.004	0.006	NA	0.024	1.1e-04	0.11000	0.06400	NA	0.00084

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Triglycerides	344.0	563.4	625.0	-25.0	-22.4
High cholesterol (Self-reported)	96.9	171.9	204.5	-14.3	-11.8
HDL Cholesterol	70.6	117.8	129.0	10.3	11.4
Cholesterol lowering medication	58.5	86.2	108.2	-10.4	-8.0
Medication: Atorvastatin	54.2	66.9	84.4	-9.2	-7.0
Medication: Cholesterol lowering	53.9	83.8	97.5	-9.9	-8.4
LDL Cholesterol	37.1	58.7	65.9	-8.1	-7.2
Medication: Simvastatin	35.0	51.5	60.5	-7.8	-6.5
Medication for cholesterol, blood pressure or diabetes	29.1	48.2	56.8	7.5	6.3
Cardiovascular Disease	19.7	65.1	77.8	-8.8	-7.2
Coronary Artery Disease (CAD)	11.2	13.4	15.7	-4.0	-3.3
Heart disease (siblings)	9.9	12.2	13.2	-3.6	-3.3
Blood Eosinophil Count	9.6	73.7	81.9	9.1	8.1
Blood Platelet Count	8.8	102.2	132.2	11.5	8.5
Number of full brothers	8.4	10.6	11.5	-3.1	-3.4
Heart disease (mother)	8.0	9.8	11.0	-3.3	-2.9
Prospective memory result	7.2	8.8	10.5	2.7	3.2
Medication: Aspirin	7.0	9.3	9.9	-3.1	-2.9
Gout (self-reported)	6.9	9.4	10.8	-3.3	-2.8
Medication: Aspirin	6.5	8.5	8.8	-3.0	-2.9
Angina	6.4	8.4	9.7	-3.1	-2.7
Angina (self-reported)	6.1	8.1	9.6	-3.1	-2.6
Heart attack	5.6	7.2	7.6	-2.8	-2.6
Number of self-reported non-cancer illnesses	5.5	9.5	10.3	-3.2	-2.9
Heart attack/myocardial infarction (self-reported)	5.2	6.7	7.1	-2.7	-2.5
Taking other prescription medications	4.6	7.0	7.8	-2.5	-2.8
Medication: Ramipril	4.4	5.7	6.8	-2.6	-2.1
Number of treatments/medications taken	4.2	7.5	10.2	-3.2	-2.2
Father’s age at death	4.1	5.5	5.6	2.4	2.3
Medication: Amlodipine	3.9	5.5	6.1	-2.5	-2.2
Illnesses of father: Heart disease	3.8	5.2	5.7	-2.4	-2.2
Illnesses of father: High blood pressure	3.7	4.6	6.7	-2.6	-1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	3.6	4.8	5.3	-2.3	-2.1
Frequency of tiredness / lethargy in last 2 weeks	3.5	5.6	6.2	-2.3	-2.5
Medication: Allopurinol	3.5	4.6	5.5	-2.4	-1.9
Had major operations	3.5	4.1	5.1	-2.3	-1.8
Friendships satisfaction	3.5	4.3	5.1	-1.9	-2.3
Happiness	3.4	4.1	4.8	-1.9	-2.2
Number of children fathered	3.3	3.7	4.6	-2.1	-1.7
Breast Cancer	3.1	7.4	7.5	-2.7	-2.7
Medication: Blood pressure	3.1	5.5	7.3	-2.7	-1.9
Overall health rating	3.1	6.6	7.0	-2.6	-2.5
Medication for cholesterol	2.8	4.2	7.3	2.7	1.0
Verbal and Numeric Reasoning (VNR)	2.6	6.3	6.9	-2.6	-2.4
Alcohol drinker status: Never	2.6	3.1	3.3	1.8	1.7
Illnesses of siblings	2.5	3.5	3.9	2.0	1.8
Guilty feelings	2.5	3.8	3.8	-2.0	-2.0
Depression (Nagel 2018)	2.4	3.5	3.6	-1.9	-1.9
Fluid intelligence score	2.4	4.9	5.8	-2.4	-2.0
Loneliness, isolation	2.4	3.3	4.0	-2.0	-1.6
Supplements: Vitamin C	2.3	2.7	2.9	1.7	1.6
Average weekly red wine intake	2.3	3.4	3.5	-1.9	-1.8
HbA1C	2.1	2.3	2.6	1.4	1.6
Medication: Ibuprofen (e.g. Nurofen)	2.1	2.7	2.8	1.6	1.7
Ever highly irritable/argumentative for 2 days	2.1	2.5	2.6	-1.6	-1.5
Financial situation satisfaction	2.1	2.6	2.9	-1.7	-1.5
Ever smoked	2.1	3.7	3.8	1.9	1.9
Fasting Glucose	2.0	2.4	2.9	-1.7	-1.4
Hearing difficulty/problems: Yes	2.0	3.1	4.0	-1.5	-2.0
Intelligence (Savage-Jansen 2018)	1.9	5.8	6.8	-2.6	-2.2
Medication for hormone replacement therapy	1.9	2.2	3.2	1.0	1.8
Relative age voice broke	1.9	3.0	3.6	-1.5	-1.9
Supplements: Glucosamine	1.8	2.3	2.3	1.5	1.5
Hair/balding pattern: Pattern 4	1.8	4.3	4.5	-2.0	-2.1
Family relationship satisfaction	1.8	2.2	2.4	-1.4	-1.6
Illness, injury, bereavement, stress in last 2 years	1.8	2.2	3.5	0.9	1.9
Myopia	1.8	2.5	3.8	-1.9	-1.1
Ulcerative Colitis (UC)	1.7	3.1	4.4	1.3	2.1
Had other major operations	1.7	2.1	2.5	-1.3	-1.6
Headache pain in last month	1.7	2.9	3.3	1.6	1.8
Alcohol drinker status: Previous	1.7	1.9	2.7	-1.1	-1.6
Frequency of depressed mood in last 2 weeks	1.6	2.2	2.3	-1.5	-1.4
Stomach or abdominal pain in last month	1.6	1.9	2.3	1.5	1.3
Financial difficulties in last 2 years	1.6	2.2	2.7	-1.3	-1.6
Emphysema/chronic bronchitis	1.6	1.8	1.8	-1.3	-1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.9	2.7	1.6	1.0
Eye problems/disorders: Cataract	1.6	1.8	2.8	-0.9	-1.7
Illnesses of father: None of the above (group 1)	1.6	1.9	2.4	1.6	1.2
Pain type(s) experienced in last month: Hip pain	1.6	2.0	2.2	1.4	1.5
Number of incorrect matches in round	1.5	2.5	3.0	1.4	1.7
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.3	2.6	-1.6	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.5	2.0	2.0	-1.4	-1.4
Mother’s age at death	1.5	1.9	2.5	1.6	1.2
Number of operations (self-reported)	1.5	2.3	2.8	-1.7	-1.3
Serious illness, injury or assault of a close relative in last 2 years	1.4	1.6	2.2	-1.5	-1.0
Medication: Lansoprazole	1.4	1.6	1.7	-1.2	-1.3
Irritable Bowel Disease (IBD)	1.3	3.1	4.7	1.2	2.2
Prostate Cancer	1.3	1.8	2.4	1.1	1.5
Ever used hormone-replacement therapy (HRT)	1.3	1.6	1.8	1.3	1.2
Shortness of breath walking on level ground	1.3	1.6	1.7	-1.3	-1.2
Smoking status: Previous	1.3	2.0	2.9	1.7	1.1
Supplements: Fish oil (including cod liver oil)	1.3	1.6	1.7	1.3	1.2
Vascular/heart problems diagnosed by doctor	1.3	3.5	5.1	2.3	1.4
Pulse rate	1.2	2.0	2.2	1.5	1.4
Comparative height size at age 10	1.2	6.6	8.2	2.9	2.2
Mood swings	1.2	2.2	2.7	-1.7	-1.3
Smoking Status	1.1	2.6	3.4	1.9	1.4
Pack years adult smoking proportion	1.1	1.7	2.7	-1.6	-0.9
Serious illness, injury or assault to yourself	1.1	1.3	2.1	-0.7	-1.4
Trunk fat mass	1.1	4.8	5.0	2.2	2.1
Past tobacco smoking	1.1	2.0	2.6	-1.6	-1.2
Hair/balding pattern: Pattern 2	1.1	1.4	1.9	-1.4	-0.9
Glaucoma (self-reported)	1.1	1.3	1.5	1.0	1.2
Long-standing illness, disability or infirmity	1.1	1.7	1.8	-1.3	-1.3
Diabetes (father)	1.0	1.2	1.2	1.1	1.1
Townsend deprivation index at recruitment	1.0	1.4	1.4	-1.1	-1.2
Arm fat percentage (right)	1.0	3.8	3.8	1.9	2.0
High blood pressure (siblings)	1.0	1.4	1.7	-1.3	-1.0
Body fat percentage	1.0	4.1	4.3	2.0	2.1
Whole body fat mass	1.0	4.1	4.3	2.1	2.0
Arm fat percentage (left)	1.0	3.8	4.0	1.9	2.0
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	1.3	-0.9	-1.1
Arm fat mass (left)	1.0	4.0	4.3	2.1	1.9
Ever depressed for a whole week	1.0	1.3	1.6	-1.0	-1.3
Height	0.9	18.2	19.7	4.4	4.1
Relative age of first facial hair	0.9	1.8	2.1	-1.3	-1.4
Trunk fat percentage	0.9	3.8	3.8	1.9	1.9
Qualifications: A levels/AS levels or equivalent	0.9	1.9	2.5	-1.1	-1.6
Arm fat mass (right)	0.9	3.5	3.8	2.0	1.8
Age at last live birth	0.9	1.2	1.4	-1.1	-1.2
Wears glasses or contact lenses	0.9	1.0	1.4	0.8	1.2
Leg fat percentage (left)	0.9	3.2	3.6	1.7	1.9
Mean Putamen Volume	0.8	0.9	1.1	-1.1	-0.8
Hearing difficulty/problems with background noise	0.8	1.3	1.4	-1.1	-1.2
Tense / ‘highly strung’	0.8	1.3	1.4	1.1	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	1.5	-1.2	-1.0
Medication: Ventolin 100micrograms inhaler	0.8	1.0	1.1	0.9	1.1
Leg pain on walking	0.8	1.0	1.1	-1.0	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	0.9	1.0	1.0
Leg fat mass (left)	0.8	3.3	3.5	1.9	1.7
Crohns Disease (2017)	0.7	1.5	2.2	0.9	1.5
Lupus	0.7	1.0	1.3	0.8	1.2
Primary Biliary Cirrhosis	0.7	1.0	1.3	1.1	0.9
Type 2 Diabetes (T2D) (2012)	0.7	0.8	1.1	-1.0	-0.7
Waist Hip Ratio (WHR)	0.7	2.9	3.1	1.7	1.8
Sensitivity / hurt feelings	0.7	1.1	1.5	-1.2	-0.9
Diabetes (mother)	0.7	1.0	1.1	0.9	1.1
High blood pressure	0.7	1.8	2.9	-1.7	-0.9
Chronic bronchitis/emphysema (father)	0.7	0.8	0.8	0.9	0.8
Waist circumference	0.7	2.7	3.0	1.5	1.7
Weight	0.7	3.2	3.8	2.0	1.6
Exposure to tobacco smoke at home	0.7	0.7	1.0	-1.0	-0.7
Leg fat percentage (right)	0.7	2.6	2.9	1.5	1.7
Age at first live birth	0.7	1.2	1.5	-1.0	-1.2
Migraine (self-reported)	0.7	0.8	1.4	1.2	0.4
Leg fat mass (right)	0.7	2.7	3.0	1.7	1.6
Number of full sisters	0.7	0.8	1.3	-1.1	-0.7
Osteoporosis (self-reported)	0.7	0.8	1.0	0.8	1.0
Leg predicted mass (right)	0.7	3.5	4.3	2.1	1.6
Eye problems/disorders: Glaucoma	0.7	0.8	1.0	0.8	1.0
Basal metabolic rate	0.7	3.6	4.7	2.2	1.6
Pack years of smoking	0.7	1.0	1.7	-1.3	-0.6
Allergy or Eczema	0.6	1.5	2.5	0.8	1.6
Hand grip strength (left)	0.6	1.6	2.1	-1.0	-1.4
Average weekly spirits intake	0.6	0.8	1.0	-0.8	-1.0
Systolic blood pressure, automated reading	0.6	1.8	2.1	1.4	1.2
Leg fat-free mass (left)	0.6	3.2	4.0	2.0	1.5
Age when periods started (menarche)	0.6	1.5	2.4	-0.8	-1.6
Leg predicted mass (left)	0.6	3.1	4.0	2.0	1.5
Illnesses of mother	0.6	0.8	0.8	0.9	0.8
Trunk predicted mass	0.6	3.2	4.4	2.1	1.4
Exposure to tobacco smoke outside home	0.6	0.8	1.4	0.4	1.2
Medication: Seretide 50 evohaler	0.6	0.6	0.7	0.7	0.9
Illnesses of siblings: Diabetes	0.6	0.7	1.0	0.6	1.0
Whole body fat-free mass	0.6	3.2	4.3	2.1	1.5
Leg fat-free mass (right)	0.6	3.3	4.2	2.0	1.6
Handedness (chirality/laterality): Left-handed	0.6	0.7	0.8	-0.9	-0.7
Whole body water mass	0.6	3.5	4.6	2.1	1.6
Medication: Bendroflumethiazide	0.6	0.9	1.3	-1.1	-0.7
Alzheimer’s Disease (in father)	0.5	0.5	0.5	0.7	0.7
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	0.6	-0.8	-0.7
Medication: Co-codamol	0.5	0.6	0.8	0.6	0.9
Had menopause	0.5	0.6	1.0	1.0	0.5
Trunk fat-free mass	0.5	2.8	3.9	2.0	1.3
Pulse wave Arterial Stiffness index	0.5	0.6	0.8	0.7	0.9
Medication: Paracetamol	0.5	0.8	1.0	1.0	0.7
Arm fat-free mass (right)	0.5	2.7	3.5	1.9	1.4
Eye problems/disorders: None of the above	0.5	0.6	1.0	-1.0	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.2	-0.3	-1.1
Alcohol intake frequency.	0.5	1.2	1.3	1.1	1.1
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	0.7	0.7	0.8
Asthma (self-reported)	0.5	1.1	1.2	-1.1	-1.0
Arm fat-free mass (left)	0.5	2.7	3.5	1.9	1.4
Irritability	0.5	0.9	1.1	0.9	1.0
Arm predicted mass (left)	0.5	2.8	3.8	1.9	1.4
Bipolar Disorder (2011)	0.4	0.4	0.8	0.9	0.0
Body Mass Index (BMI) (2010)	0.4	0.6	0.7	0.7	0.8
Neuroticism (2016)	0.4	0.6	1.0	-0.5	-1.0
Rheumatoid Arthritis	0.4	0.5	1.0	1.0	0.1
Blood Red Count	0.4	3.6	3.8	-2.0	-1.9
Type 2 Diabetes (T2D) (2018)	0.4	0.8	0.9	-0.9	-0.9
Fed-up feelings	0.4	0.8	0.9	-1.0	-0.8
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	0.9	0.6	0.9
Hip circumference	0.4	1.6	2.0	1.4	1.1
Hair/balding pattern: Pattern 3	0.4	0.6	0.7	0.9	0.7
Asthma	0.4	0.8	0.9	-0.9	-0.8
Breastfed as a baby	0.4	0.4	0.5	0.7	0.6
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	0.9	-1.0	-0.2
Forced vital capacity (FVC), Best measure	0.4	1.5	2.0	1.4	1.1
Health satisfaction	0.4	0.5	0.7	-0.5	-0.8
Arm predicted mass (right)	0.4	2.3	3.0	1.7	1.2
Knee pain experienced in last month	0.4	0.6	0.9	1.0	0.6
Mineral and other dietary supplements	0.4	0.6	0.7	-0.7	-0.8
Average weekly beer plus cider intake	0.4	0.5	0.7	0.9	0.5
Depressed Affect (Nagel 2018)	0.3	0.7	1.0	-1.0	-0.7
Neuroticism (Nagel 2018)	0.3	0.8	1.2	-1.1	-0.6
Schizophrenia (2018)	0.3	0.6	0.8	0.5	0.9
Major Depression (MDD)	0.3	0.4	0.6	-0.7	-0.4
Ever had hysterectomy (womb removed)	0.3	0.3	0.5	-0.7	-0.4
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.4	-0.6	-0.5
Multivitamins +/- minerals	0.3	0.3	0.3	-0.6	-0.6
Medication: Atenolol	0.3	0.3	0.7	-0.8	-0.2
Body mass index (BMI)	0.3	1.3	1.4	1.2	1.0
Allergy	0.3	0.6	1.0	1.0	0.5
Falls in the last year	0.3	0.3	0.6	-0.8	-0.3
Noisy workplace	0.3	0.3	0.4	0.7	0.5
Standing height	0.3	2.6	3.5	1.9	1.3
Length of working week for main job	0.3	0.3	0.4	0.6	0.6
Birth weight of first child	0.3	0.5	0.8	-0.4	-0.9
Comparative body size at age 10	0.3	0.8	0.9	-1.0	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	0.4	-0.5	-0.6
Pulse wave peak to peak time	0.3	0.4	0.5	-0.5	-0.7
Medication: Ibuprofen	0.3	0.4	0.4	0.6	0.6
Hypertension (Self-reported)	0.3	0.9	1.6	-1.3	-0.5
Ever had bowel cancer screening	0.3	0.4	0.5	-0.7	-0.5
Commuting to job workplace: Walk	0.3	0.3	0.3	-0.5	0.5
Bipolar Disorder (2018)	0.2	0.4	0.4	-0.6	-0.6
Alzheimer’s Disease (in mother)	0.2	0.2	0.4	0.6	-0.1
Alzheimer’s Disease (including proxy)	0.2	0.2	0.3	0.6	0.4
Ovarian Cancer	0.2	0.3	0.5	0.3	0.7
Schizophrenia (2014)	0.2	0.4	0.6	0.3	0.8
Ulcerative Colitis	0.2	0.2	0.4	0.3	0.6
Systolic Blood Pressure	0.2	1.2	1.6	-1.3	-0.9
Tanning	0.2	1.9	2.4	1.2	1.6
Vitamin and mineral supplements	0.2	0.2	0.3	0.4	0.5
Supplements: Zinc	0.2	0.2	0.3	0.5	0.2
Tinnitus: Yes, but not now, but have in the past	0.2	0.3	0.5	0.7	0.1
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.4	0.6	0.2
Medication: Levothyroxine sodium	0.2	0.4	0.6	-0.8	-0.3
Alcohol usually taken with meals	0.2	0.3	0.3	-0.5	-0.5
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.4	-0.6	-0.3
Neuroticism score	0.2	0.4	0.5	-0.7	-0.5
Time employed in main current job	0.2	0.3	0.5	-0.2	0.7
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	0.9	1.0	0.6
Depression (self-reported)	0.2	0.2	0.3	0.6	0.3
Lung cancer (father)	0.2	0.2	0.2	-0.4	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	0.7	0.6	0.8
Loud music exposure frequency	0.2	0.2	0.2	-0.4	-0.5
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.6	-0.5	-0.7
Suffer from ‘nerves’	0.2	0.3	0.4	-0.7	-0.5
Chest pain or discomfort	0.2	0.3	0.4	0.7	0.4
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.2	-0.5	-0.4
Osteoarthritis (self-reported)	0.2	0.2	0.3	-0.4	-0.6
Smoking status: Current	0.2	0.2	0.3	-0.5	-0.5
Commuting to job workplace: Public transport	0.2	0.2	0.3	0.3	0.6
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.4	0.6	-0.4
Basal cell carcinoma (self-reported)	0.2	0.2	0.4	0.6	-0.1
Worry (Nagel 2018)	0.1	0.1	0.2	-0.2	0.5
Age at First Birth	0.1	0.1	0.3	-0.5	-0.0
Crohns Disease (2012)	0.1	0.1	0.1	-0.4	-0.3
Blood White Count	0.1	0.7	1.4	1.2	0.3
Heel T-Score	0.1	0.9	1.8	-1.4	0.2
Hypothyroidism (self reported)	0.1	0.2	0.4	0.6	-0.0
Respiratory disease	0.1	0.2	0.3	-0.2	-0.5
Lung FEV1/FVC ratio	0.1	0.7	1.2	-0.6	1.1
Chronotype (morning person)	0.1	0.2	0.3	0.3	0.5
Severe depression (siblings)	0.1	0.1	0.1	0.3	-0.2
Impedance of leg (right)	0.1	0.3	0.3	-0.6	-0.5
Qualifications: CSEs or equivalent	0.1	0.2	0.2	-0.3	-0.5
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.4	-0.7	0.2
High blood pressure (mother)	0.1	0.1	0.3	-0.5	-0.0
Nervous feelings	0.1	0.2	0.4	0.1	0.6
Forced vital capacity (FVC)	0.1	0.5	1.0	1.0	0.1
Mouth/teeth dental problems	0.1	0.1	0.2	0.4	0.2
Diabetes (self-reported)	0.1	0.1	0.2	-0.5	-0.1
Impedance of arm (right)	0.1	0.3	0.4	0.5	0.6
Alcohol intake versus 10 years previously	0.1	0.1	0.2	0.4	0.3
Number of live births	0.1	0.1	0.1	-0.3	-0.2
Mouth/teeth dental problems: Dentures	0.1	0.2	0.3	0.3	0.5
Peak expiratory flow (PEF)	0.1	0.3	0.6	-0.8	-0.2
Blood clot in the leg (DVT)	0.1	0.1	0.2	0.4	-0.2
Birth weight	0.1	0.1	0.1	-0.3	-0.3
Worry too long after embarrassment	0.1	0.2	0.3	-0.2	-0.6
Qualifications: College or University degree	0.1	0.3	0.4	0.6	-0.4
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.1	0.2	-0.3
Neck or shoulder pain in last month	0.1	0.1	0.3	-0.5	-0.1
Medication: Omeprazole	0.1	0.1	0.2	-0.4	-0.1
Qualifications: nursing, teaching	0.1	0.1	0.2	0.5	0.3
Breast cancer (self-reported)	0.1	0.1	0.1	0.4	0.3
Medication: Gliclazide	0.1	0.1	0.1	-0.3	-0.1
Average weekly champagne plus white wine intake	0.1	0.2	0.2	0.5	-0.4
Miserableness	0.1	0.2	0.3	-0.6	-0.2
Ever taken oral contraceptive pill	0.1	0.2	0.3	-0.1	0.6
Medication: Blood pressure	0.1	0.3	0.5	-0.7	0.3
Medication: Paracetamol	0.1	0.1	0.2	0.4	0.4
Fractured/broken bones in last 5 years	0.1	0.2	0.3	-0.3	-0.5
Diastolic blood pressure, automated reading	0.1	0.3	0.5	0.7	0.4
Unable to work because of sickness or disability	0.1	0.1	0.2	-0.1	-0.4
Commuting to job workplace: Cycle	0.1	0.1	0.1	0.3	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.3	0.1	0.5
Pain experienced in last month	0.1	0.2	0.2	-0.4	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.2	0.4	-0.2
Bipolar Disorder or Schizophrenia	0.0	0.1	0.1	0.0	0.3
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	-0.0	0.1
Reaction Time	0.0	0.1	0.1	-0.1	-0.3
BMI	0.0	0.0	0.0	0.0	-0.1
Lung FVC	0.0	0.2	0.3	0.6	0.1
Neuroticism	0.0	0.0	0.0	-0.0	-0.1
Hair Pigment	0.0	0.2	0.4	-0.6	0.2
Other serious medical condition/disability diagnosed by doctor	0.0	0.0	0.0	0.1	-0.2
Medication: Metformin	0.0	0.0	0.0	-0.1	0.1
Hand grip strength (right)	0.0	0.1	0.1	0.3	-0.4
Current tobacco smoking	0.0	0.0	0.0	-0.2	-0.1
Average weekly fortified wine intake	0.0	0.0	0.0	0.0	0.1
Maternal smoking around birth	0.0	0.0	0.0	-0.1	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.1	-0.0	0.4
Sitting height	0.0	0.2	0.4	0.7	0.2
Impedance of leg (left)	0.0	0.0	0.1	-0.2	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.1	-0.2	0.3
Qualifications: None of the above	0.0	0.0	0.0	-0.1	0.1
Pain all over the body in last month	0.0	0.0	0.1	0.2	0.1
Worrier / anxious feelings	0.0	0.1	0.1	-0.3	0.1
Impedance of arm (left)	0.0	0.1	0.2	0.2	0.4
Pulse wave reflection index	0.0	0.0	0.0	-0.1	0.2
Qualifications: O levels/GCSEs or equivalent	0.0	0.0	0.0	-0.1	0.0
Chronic bronchitis/emphysema (mother)	0.0	0.0	0.0	-0.1	-0.2
Wheeze or whistling in the chest in last year	0.0	0.0	0.0	0.0	-0.2
Medication for pain relief, constipation, heartburn	0.0	0.0	0.0	-0.1	-0.0
Mean time to correctly identify matches	0.0	0.1	0.1	0.2	0.3
Pulse rate, automated reading	0.0	0.1	0.2	-0.4	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.1	0.1	-0.2	-0.2
Diabetes diagnosed by doctor	0.0	0.1	0.1	-0.4	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.0	0.0	0.1	0.1	-0.3
Back pain experienced in last month	0.0	0.0	0.0	-0.1	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.1	0.1	-0.3	-0.3
Hearing aid user	0.0	0.0	0.0	-0.1	0.0
Tinnitus: Yes, now most or all of the time	0.0	0.0	0.1	-0.1	0.3
Medication: Lisinopril	0.0	0.0	0.0	-0.1	-0.1
Risk taking	0.0	0.1	0.1	0.3	-0.2
Age started oral contraceptive pill	0.0	0.0	0.1	-0.0	-0.3
Supplements: Calcium	0.0	0.1	0.1	0.2	0.3
Impedance of whole body	0.0	0.1	0.1	-0.4	-0.0

Hub : Genes

ZNF259

Models

Trait associations