[Hub]/) : Traits : Medication: Simvastatin : ← →

chr19:48,464,978-49,872,085

Best TWAS P=1.67e-08 · Best GWAS P=1.11e-08 conditioned to 0.13

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 METSIM Adipose NTN5 0.13 0.10 bslmm 450 0.14 3.2e-20 5.3 5.4 5.7e-08 0.69 0.04 0.96 FALSE
2 The Cancer Genome Atlas Breast Invasive Carcinoma NTN5 0.02 0.01 enet 11 0.01 7.6e-04 5.3 5.4 7.4e-08 0.85 0.01 0.92 FALSE
3 The Cancer Genome Atlas Colon Adenocarcinoma FUT2 0.18 0.22 enet 12 0.18 6.8e-11 5.6 -5.3 8.9e-08 -0.97 0.01 0.99 FALSE
4 The Cancer Genome Atlas Colon Adenocarcinoma SEC1 0.05 0.04 enet 11 0.01 8.5e-02 5.5 -5.3 1.1e-07 -0.93 0.01 0.90 FALSE
5 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma FUT2 0.10 0.01 blup 51 0.05 9.8e-04 5.6 -5.2 1.9e-07 -0.89 0.01 0.94 FALSE
6 The Cancer Genome Atlas Brain Lower Grade Glioma NTN5 0.05 0.04 lasso 2 0.02 6.7e-04 5.3 5.3 1.0e-07 0.97 0.01 0.99 FALSE
7 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FUT2 0.05 0.08 lasso 2 0.08 6.7e-09 5.6 -5.6 2.1e-08 -0.99 0.01 0.99 FALSE
8 The Cancer Genome Atlas Pancreatic Adenocarcinoma FUT2 0.08 0.12 lasso 4 0.11 2.5e-05 5.3 -5.3 1.4e-07 -0.95 0.02 0.96 FALSE
9 The Cancer Genome Atlas Rectum Adenocarcinoma FUT2 0.26 0.28 lasso 10 0.22 5.2e-06 5.3 -5.1 3.0e-07 -0.96 0.02 0.97 FALSE
10 The Cancer Genome Atlas Stomach Adenocarcinoma FUT2 0.14 0.16 lasso 8 0.14 4.9e-10 5.3 -5.3 1.3e-07 -0.96 0.02 0.98 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma NTN5 0.11 0.07 blup 43 0.09 2.6e-09 5.3 5.6 1.7e-08 0.89 0.01 0.99 TRUE