[Hub]/) : Traits : Medication: Simvastatin :

chr19:44,614,208-46,098,885

Best TWAS P=9.64e-13 · Best GWAS P=5.01e-70 conditioned to 3.12e-44

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Mucosa PVRL2 0.15 0.01 enet 10 0.02 1.7e-02 -7.6 6.5 5.8e-11 -0.16 0.14 0.04 TRUE
2 GTEx Stomach BCAM 0.33 0.00 enet 3 0.01 9.6e-02 1.9 -5.5 2.8e-08 0.27 0.07 0.08 TRUE
3 YFS Blood TOMM40 0.04 0.00 bslmm 371 0.01 2.6e-04 -5.8 6.5 6.6e-11 -0.08 0.05 0.02 TRUE
4 The Cancer Genome Atlas Pancreatic Adenocarcinoma APOC2 0.18 0.12 enet 14 0.13 5.2e-06 -1.8 6.1 1.2e-09 -0.19 0.64 0.05 TRUE
5 The Cancer Genome Atlas Thyroid Carcinoma PVRL2 0.09 0.05 blup 55 0.03 4.6e-04 1.9 -7.1 9.6e-13 0.31 0.46 0.09 TRUE