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Medication: Simvastatin
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chr19:44,614,208-46,098,885
Best TWAS P=9.64e-13 · Best GWAS P=5.01e-70 conditioned to 3.12e-44
44.6M
44.8M
45M
45.2M
45.4M
45.6M
45.8M
46M
0
20
40
60
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
5
The Cancer Genome Atlas
Thyroid Carcinoma
PVRL2
0.09
0.05
blup
55
0.03
4.6e-04
1.9
-7.1
9.6e-13
0.31
0.46
0.09
TRUE
1
GTEx
Esophagus Mucosa
PVRL2
0.15
0.01
enet
10
0.02
1.7e-02
-7.6
6.5
5.8e-11
-0.16
0.14
0.04
TRUE
3
YFS
Blood
TOMM40
0.04
0.00
bslmm
371
0.01
2.6e-04
-5.8
6.5
6.6e-11
-0.08
0.05
0.02
TRUE
4
The Cancer Genome Atlas
Pancreatic Adenocarcinoma
APOC2
0.18
0.12
enet
14
0.13
5.2e-06
-1.8
6.1
1.2e-09
-0.19
0.64
0.05
TRUE
2
GTEx
Stomach
BCAM
0.33
0.00
enet
3
0.01
9.6e-02
1.9
-5.5
2.8e-08
0.27
0.07
0.08
TRUE