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chr12:111,154,626-113,517,494

Best TWAS P=8.63e-10 · Best GWAS P=4.47e-16 conditioned to 7.64e-08

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Artery Tibial	HECTD4	0.05	0.02	lasso	3	0.01	3.1e-02	6.8	6.1	8.6e-10	0.81	0.02	0.91	TRUE
2	GTEx	Adipose Subcutaneous	HECTD4	0.06	0.00	enet	15	0.02	1.0e-02	-3.1	5.9	2.9e-09	0.66	0.07	0.81	FALSE
4	YFS	Blood	SH2B3	0.05	0.01	enet	22	0.02	3.3e-07	-4.3	5.7	9.6e-09	0.66	0.37	0.63	FALSE
5	YFS	Blood	TRAFD1	0.04	0.02	lasso	2	0.01	2.9e-05	4.3	5.1	2.7e-07	0.54	0.09	0.85	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ATXN2	0.02	0.03	enet	8	0.02	4.8e-04	-3.5	5.1	2.9e-07	0.57	0.22	0.70	FALSE