Best TWAS P=7.59e-11 · Best GWAS P=6.89e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | LRP1 | 0.15 | 0.12 | lasso | 2 | 0.10 | 3.9e-08 | -6.5 | 6.5 | 7.6e-11 | -1.00 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Artery Tibial | STAT6 | 0.08 | 0.03 | enet | 4 | 0.02 | 1.3e-02 | -5.9 | -5.8 | 8.7e-09 | 0.61 | 0.09 | 0.70 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | STAT6 | 0.04 | 0.01 | blup | 47 | 0.01 | 2.3e-02 | -5.6 | -6.3 | 3.7e-10 | 0.79 | 0.02 | 0.82 | FALSE |