Best TWAS P=1.38e-09 · Best GWAS P=4.83e-09 conditioned to 0.219
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | ARHGAP42 | 0.22 | 0.15 | enet | 18 | 0.19 | 1.7e-10 | -5.8 | -5.5 | 4.3e-08 | 0.81 | 0.00 | 0.99 | FALSE |
2 | GTEx | Artery Aorta | TMEM133 | 0.30 | 0.15 | enet | 34 | 0.19 | 7.1e-11 | -5.5 | -5.4 | 5.9e-08 | 0.64 | 0.01 | 0.99 | FALSE |
3 | GTEx | Artery Tibial | ARHGAP42 | 0.24 | 0.24 | lasso | 4 | 0.24 | 2.4e-18 | -5.5 | -5.8 | 6.1e-09 | 0.90 | 0.01 | 0.99 | FALSE |
4 | GTEx | Artery Tibial | TMEM133 | 0.26 | 0.25 | enet | 28 | 0.27 | 1.3e-21 | -5.5 | -6.1 | 1.4e-09 | 0.86 | 0.01 | 0.99 | TRUE |