TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Medication: Levothyroxine sodium
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chr2:190,818,878-192,254,289
Best TWAS P=7.36e-08 · Best GWAS P=8.44e-19 conditioned to 3.73e-15
190.8M
191M
191.2M
191.4M
191.6M
191.8M
192M
192.2M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
NAB1
0.06
0.06
lasso
2
0.04
4.3e-06
5.0
-5.4
7.4e-08
-0.22
0.97
0.00
TRUE
2
GTEx
Testis
NAB1
0.14
0.06
enet
20
0.10
5.1e-05
3.8
5.4
8.5e-08
0.25
0.73
0.03
FALSE