Best TWAS P=6.66e-09 · Best GWAS P=1.15e-08 conditioned to 0.00864
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | ERI1 | 0.11 | 0.08 | lasso | 5 | 0.10 | 5.1e-06 | 4.6 | -5.3 | 1.2e-07 | -0.71 | 0.06 | 0.94 | FALSE |
2 | GTEx | Artery Tibial | ERI1 | 0.05 | 0.02 | lasso | 7 | 0.01 | 3.2e-02 | 5.4 | -5.5 | 5.2e-08 | -0.80 | 0.04 | 0.91 | FALSE |
3 | GTEx | Cells Transformed fibroblasts | ERI1 | 0.34 | 0.35 | lasso | 7 | 0.35 | 1.9e-27 | 4.6 | -5.2 | 2.3e-07 | -0.69 | 0.29 | 0.70 | FALSE |
4 | GTEx | Esophagus Muscularis | ERI1 | 0.12 | 0.09 | enet | 13 | 0.08 | 7.7e-06 | 4.4 | -5.1 | 2.8e-07 | -0.77 | 0.09 | 0.90 | FALSE |
5 | GTEx | Muscle Skeletal | MFHAS1 | 0.07 | 0.04 | lasso | 4 | 0.04 | 1.4e-04 | 4.3 | 5.3 | 1.1e-07 | 0.75 | 0.06 | 0.94 | FALSE |
6 | GTEx | Nerve Tibial | ERI1 | 0.07 | 0.01 | enet | 16 | 0.01 | 4.2e-02 | -4.4 | -5.7 | 1.3e-08 | -0.74 | 0.14 | 0.63 | FALSE |
7 | GTEx | Pancreas | ERI1 | 0.08 | 0.00 | enet | 16 | 0.04 | 6.6e-03 | 4.7 | -5.8 | 6.7e-09 | -0.63 | 0.14 | 0.37 | TRUE |