Best TWAS P=6.13e-09 · Best GWAS P=1.36e-06 conditioned to 0.556
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | ACP2 | 0.17 | 0.03 | lasso | 6 | 0.03 | 4.2e-02 | -4.1 | 5.8 | 6.1e-09 | 0.77 | 0.05 | 0.78 | TRUE |
| 2 | METSIM | Adipose | NR1H3 | 0.03 | 0.03 | lasso | 6 | 0.04 | 4.7e-06 | 4.7 | -5.4 | 5.6e-08 | -0.90 | 0.03 | 0.94 | FALSE |