[Hub]/) : Traits : Sitting height : ← →

chr10:80,443,273-82,223,767

Best TWAS P=1.87e-38 · Best GWAS P=8.47e-22 conditioned to 0.176

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	ZCCHC24	0.12	0.01	lasso	6	0.03	3.4e-03	9.15	13.0	1.9e-38	0.80	0.01	0.97	TRUE
2	GTEx	Adipose Visceral Omentum	BEND3P3	0.27	0.13	lasso	10	0.13	3.0e-07	7.42	-8.5	2.5e-17	0.01	0.28	0.72	FALSE
3	GTEx	Adipose Visceral Omentum	RP11-119F19.2	0.14	0.14	lasso	3	0.12	6.3e-07	6.87	-6.8	1.1e-11	0.05	0.76	0.12	FALSE
4	GTEx	Artery Aorta	BEND3P3	0.19	0.05	enet	22	0.09	7.5e-06	6.73	-8.6	8.1e-18	-0.03	0.71	0.21	FALSE
5	GTEx	Artery Aorta	RP11-119F19.2	0.22	0.16	lasso	9	0.18	2.7e-10	8.35	-8.1	6.9e-16	0.03	0.66	0.33	FALSE
6	GTEx	Artery Coronary	BEND3P3	0.22	0.06	lasso	4	0.13	5.2e-05	8.35	-7.0	2.5e-12	0.01	0.09	0.34	FALSE
7	GTEx	Artery Coronary	RP11-119F19.2	0.24	0.14	lasso	6	0.12	7.0e-05	9.35	-9.2	2.5e-20	0.01	0.07	0.86	FALSE
8	GTEx	Artery Tibial	BEND3P3	0.22	0.07	enet	14	0.10	5.8e-08	8.35	-7.7	1.7e-14	-0.01	0.54	0.45	FALSE
9	GTEx	Artery Tibial	RP11-119F19.2	0.20	0.06	enet	26	0.18	7.2e-14	8.36	-6.0	2.3e-09	0.01	0.88	0.11	FALSE
10	GTEx	Artery Tibial	RP11-506M13.3	0.12	0.06	lasso	5	0.04	3.2e-04	8.35	-9.2	4.1e-20	-0.13	0.36	0.28	FALSE
11	GTEx	Breast Mammary Tissue	RP11-119F19.2	0.16	0.08	lasso	5	0.04	3.9e-03	6.87	-6.3	2.2e-10	0.03	0.27	0.11	FALSE
12	GTEx	Cells EBV-transformed lymphocytes	BEND3P3	0.23	0.04	lasso	4	0.06	4.1e-03	6.73	-7.1	1.6e-12	0.04	0.06	0.18	FALSE
13	GTEx	Cells EBV-transformed lymphocytes	RP11-119F19.2	0.32	0.11	enet	50	0.14	2.8e-05	6.73	-5.5	4.8e-08	-0.09	0.16	0.11	FALSE
14	GTEx	Colon Transverse	BEND3P3	0.17	0.07	lasso	4	0.08	8.0e-05	7.91	-7.5	4.3e-14	0.01	0.40	0.08	FALSE
15	GTEx	Colon Transverse	RP11-119F19.2	0.21	0.18	lasso	3	0.15	1.6e-07	7.88	-7.7	9.6e-15	0.02	0.98	0.01	FALSE
16	GTEx	Esophagus Gastroesophageal Junction	BEND3P3	0.31	0.04	enet	15	0.03	3.6e-02	6.87	-6.1	1.2e-09	0.02	0.19	0.10	FALSE
17	GTEx	Esophagus Gastroesophageal Junction	RP11-119F19.2	0.21	0.12	enet	22	0.09	3.7e-04	7.88	-5.8	8.0e-09	0.00	0.33	0.20	FALSE
18	GTEx	Esophagus Mucosa	BEND3P3	0.12	0.09	enet	20	0.13	7.6e-09	8.36	-6.9	3.8e-12	0.01	0.73	0.24	FALSE
19	GTEx	Esophagus Mucosa	RP11-119F19.2	0.20	0.10	lasso	5	0.18	2.1e-12	8.36	-7.2	4.8e-13	0.04	0.93	0.07	FALSE
20	GTEx	Esophagus Muscularis	BEND3P3	0.17	0.13	lasso	6	0.13	4.4e-08	6.73	-7.8	5.1e-15	0.04	0.90	0.09	FALSE
21	GTEx	Esophagus Muscularis	RP11-119F19.2	0.18	0.11	lasso	5	0.07	3.7e-05	4.39	-5.4	5.7e-08	0.04	0.63	0.06	FALSE
22	GTEx	Heart Atrial Appendage	BEND3P3	0.20	0.13	enet	14	0.13	2.1e-06	8.38	-7.1	1.7e-12	0.02	0.35	0.45	FALSE
23	GTEx	Heart Atrial Appendage	RP11-119F19.2	0.18	0.03	lasso	7	0.05	2.5e-03	8.36	-8.4	3.4e-17	0.04	0.08	0.44	FALSE
24	GTEx	Liver	RP11-119F19.2	0.24	0.05	lasso	6	0.02	7.5e-02	7.15	6.6	5.1e-11	-0.05	0.08	0.09	FALSE
25	GTEx	Lung	BEND3P3	0.16	0.06	enet	12	0.09	2.7e-07	6.87	-6.5	1.1e-10	0.03	0.30	0.66	FALSE
26	GTEx	Lung	RP11-119F19.2	0.24	0.09	lasso	12	0.18	1.5e-13	7.15	-6.0	2.2e-09	0.01	0.39	0.61	FALSE
27	GTEx	Lung	RP11-506M13.3	0.08	0.01	lasso	3	0.02	1.3e-02	-0.75	-5.3	1.2e-07	-0.01	0.30	0.21	FALSE
28	GTEx	Nerve Tibial	BEND3P3	0.16	0.07	enet	16	0.13	1.8e-09	7.31	-6.6	3.1e-11	0.02	0.94	0.05	FALSE
29	GTEx	Nerve Tibial	RP11-506M13.3	0.08	0.04	lasso	3	0.05	3.3e-04	4.39	-5.7	1.2e-08	0.02	0.35	0.15	FALSE
30	GTEx	Ovary	BEND3P3	0.27	0.09	enet	24	0.09	3.1e-03	2.63	-8.0	1.7e-15	-0.14	0.06	0.23	FALSE
31	GTEx	Pancreas	RP11-119F19.2	0.22	0.16	lasso	10	0.09	8.8e-05	4.39	-5.5	3.3e-08	0.05	0.57	0.05	FALSE
32	GTEx	Skin Not Sun Exposed Suprapubic	BEND3P3	0.28	0.07	lasso	12	0.16	7.7e-09	6.87	-5.4	8.4e-08	0.05	0.75	0.09	FALSE
33	GTEx	Skin Not Sun Exposed Suprapubic	RP11-119F19.2	0.24	0.13	enet	11	0.20	5.1e-11	6.87	-6.0	2.0e-09	0.02	0.97	0.03	FALSE
34	GTEx	Skin Not Sun Exposed Suprapubic	RP11-506M13.3	0.12	0.00	enet	9	0.00	2.0e-01	4.39	-5.1	3.1e-07	0.11	0.05	0.14	FALSE
35	GTEx	Skin Sun Exposed Lower leg	ZCCHC24	0.09	0.00	enet	18	0.00	2.3e-01	-0.12	8.3	1.2e-16	0.39	0.02	0.62	FALSE
36	GTEx	Skin Sun Exposed Lower leg	BEND3P3	0.19	0.02	enet	33	0.07	1.7e-06	6.87	-6.2	4.6e-10	-0.01	0.43	0.41	FALSE
37	GTEx	Skin Sun Exposed Lower leg	RP11-342M3.5	0.08	0.00	enet	28	0.01	7.3e-02	0.62	5.7	1.1e-08	0.18	0.05	0.17	FALSE
38	GTEx	Testis	RP11-119F19.2	0.32	0.10	enet	18	0.13	2.1e-06	6.73	-7.1	9.8e-13	0.05	0.67	0.06	FALSE
39	GTEx	Thyroid	BEND3P3	0.20	0.12	lasso	4	0.17	4.1e-13	7.31	-8.0	1.2e-15	0.03	0.97	0.03	FALSE
40	GTEx	Thyroid	RP11-119F19.2	0.24	0.09	lasso	6	0.17	7.2e-13	6.87	-7.2	8.0e-13	0.02	0.84	0.16	FALSE
41	GTEx	Whole Blood	RP11-119F19.2	0.22	0.08	enet	24	0.10	6.3e-10	7.88	-5.8	7.4e-09	0.02	0.74	0.25	FALSE
42	ROSMAP	Brain Pre-frontal Cortex	SFTPA2	0.22	0.16	bslmm	349	0.20	2.3e-25	7.96	-7.1	1.3e-12	-0.01	0.74	0.26	FALSE
43	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ZCCHC24	0.06	0.00	blup	89	0.01	6.2e-02	7.88	10.7	1.1e-26	0.48	0.01	0.18	FALSE
44	The Cancer Genome Atlas	Breast Invasive Carcinoma	SFTPA2	0.06	0.03	enet	12	0.04	2.1e-09	6.73	-8.8	1.3e-18	0.04	0.21	0.79	FALSE
45	The Cancer Genome Atlas	Breast Invasive Carcinoma	ZCCHC24	0.03	0.01	blup	89	0.02	2.0e-04	7.91	8.6	7.2e-18	0.18	0.36	0.12	FALSE
46	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ZCCHC24	0.07	0.05	enet	9	0.04	6.7e-05	8.47	8.4	3.1e-17	0.84	0.03	0.97	FALSE
47	The Cancer Genome Atlas	Brain Lower Grade Glioma	SFTPA2	0.14	0.08	enet	8	0.10	7.6e-12	7.15	-8.8	1.9e-18	0.02	0.02	0.98	FALSE