TWAS hub - BEND3P3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.099	0.0370	1.5e-03	0.039	NA	0.065	NA	0.034	3.7e-04	NA	5.2e-06	NA	8.5e-04
2	GTEx	Adipose Visceral Omentum	0.272	0.0620	2.3e-07	0.131	NA	0.125	NA	0.130	2.7e-07	NA	4.9e-07	NA	3.1e-07
3	GTEx	Artery Aorta	0.193	0.0480	2.6e-06	0.053	NA	0.094	NA	0.094	6.6e-04	NA	7.5e-06	NA	7.7e-06
4	GTEx	Artery Coronary	0.220	0.0830	2.1e-03	0.064	NA	0.000	NA	0.126	3.4e-03	NA	3.3e-01	NA	5.2e-05
5	GTEx	Artery Tibial	0.215	0.0542	1.0e-06	0.066	NA	0.096	NA	0.085	7.0e-06	NA	5.8e-08	NA	3.2e-07
6	GTEx	Cells EBV-transformed lymphocytes	0.233	0.0910	5.6e-03	0.038	NA	0.011	NA	0.064	2.1e-02	NA	1.4e-01	NA	4.1e-03
7	GTEx	Cells Transformed fibroblasts	0.223	0.0520	8.5e-07	0.007	NA	0.085	NA	0.030	8.3e-02	NA	6.0e-07	NA	2.4e-03
8	GTEx	Colon Transverse	0.166	0.0580	4.3e-04	0.075	NA	0.073	NA	0.084	1.9e-04	NA	2.2e-04	NA	8.0e-05
9	GTEx	Esophagus Gastroesophageal Junction	0.307	0.0800	7.1e-05	0.041	NA	0.027	NA	0.016	1.4e-02	NA	3.6e-02	NA	8.3e-02
10	GTEx	Esophagus Mucosa	0.115	0.0360	6.5e-05	0.090	NA	0.127	NA	0.116	1.3e-06	NA	7.6e-09	NA	3.6e-08
11	GTEx	Esophagus Muscularis	0.170	0.0470	1.8e-05	0.126	NA	0.101	NA	0.126	4.8e-08	NA	1.1e-06	NA	4.4e-08
12	GTEx	Heart Atrial Appendage	0.201	0.0590	1.6e-04	0.131	NA	0.129	NA	0.098	1.8e-06	NA	2.1e-06	NA	3.6e-05
13	GTEx	Lung	0.157	0.0440	8.1e-06	0.060	NA	0.089	NA	0.077	2.3e-05	NA	2.7e-07	NA	1.7e-06
14	GTEx	Nerve Tibial	0.162	0.0417	1.5e-06	0.074	NA	0.130	NA	0.094	6.2e-06	NA	1.8e-09	NA	3.7e-07
15	GTEx	Ovary	0.269	0.0950	5.5e-03	0.091	NA	0.091	NA	0.075	3.1e-03	NA	3.1e-03	NA	6.7e-03
16	GTEx	Skin Not Sun Exposed Suprapubic	0.280	0.0630	3.1e-08	0.069	NA	0.146	NA	0.155	1.3e-04	NA	2.2e-08	NA	7.7e-09
17	GTEx	Skin Sun Exposed Lower leg	0.188	0.0460	1.4e-07	0.023	NA	0.071	NA	0.026	4.8e-03	NA	1.7e-06	NA	2.8e-03
18	GTEx	Thyroid	0.202	0.0430	6.4e-10	0.117	NA	0.147	NA	0.171	2.8e-09	NA	2.3e-11	NA	4.1e-13
19	GTEx	Vagina	0.304	0.1140	7.3e-03	-0.012	NA	-0.009	NA	-0.013	7.9e-01	NA	5.7e-01	NA	8.4e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Hand grip strength (right)	8.6	23.4	39.7	-2.6	-6.3	-5.5	-4.9	-5.3	-4.5	-2.0	-4.9	-4.3	-4.3	-5.5	-5.0	-6.3	-5.0	-3.7	-5.0	-5.0	-5.9	-3.3
Sitting height	6.5	46.5	74.0	-4.7	-8.5	-8.6	-7.0	-7.7	-7.1	-3.9	-7.5	-6.1	-6.9	-7.8	-7.1	-6.5	-6.6	-8.0	-5.4	-6.2	-8.0	-3.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	5.0	5.9	12.2	2.3	3.0	2.1	2.2	2.5	2.5	0.7	2.4	2.8	1.7	2.9	2.3	3.0	2.5	1.0	3.5	2.8	3.0	0.6
Chronic bronchitis/emphysema (father)	4.9	5.8	10.5	-2.2	-1.5	-2.5	-2.6	-2.6	-2.7	-1.8	-2.4	-2.5	-2.7	-2.0	-3.0	-3.2	-2.6	-1.8	-3.0	-2.3	-1.7	-1.4
Hair/balding pattern: Pattern 3	4.6	6.9	12.0	2.2	2.5	3.0	3.4	2.3	2.6	2.5	3.3	2.4	2.9	2.7	2.6	3.5	2.7	1.7	2.2	1.8	2.6	1.9
Hand grip strength (left)	4.3	11.2	22.8	-1.1	-4.8	-4.0	-3.4	-3.3	-3.3	-1.0	-4.0	-3.0	-3.1	-4.1	-3.5	-4.2	-3.2	-3.1	-3.1	-2.6	-4.4	-1.5
Forced vital capacity (FVC)	4.3	16.5	26.1	-2.6	-4.2	-5.1	-3.8	-4.3	-4.6	-1.0	-4.4	-4.2	-4.3	-4.1	-3.5	-4.5	-4.1	-5.1	-4.0	-4.7	-4.0	-2.2
HbA1C	4.2	4.6	8.8	1.8	2.4	2.8	2.2	2.1	2.5	1.7	3.0	1.6	1.8	2.5	1.9	2.0	2.2	1.5	2.4	1.4	2.4	1.7
Lung FEV1/FVC ratio	3.8	19.1	37.9	5.9	2.3	3.9	4.4	5.2	3.9	4.3	4.3	5.3	4.6	3.0	5.0	3.9	4.2	4.8	4.5	6.2	2.6	2.4
Exposure to tobacco smoke at home	3.8	4.2	7.1	-2.5	-2.0	-2.7	-1.9	-2.4	-1.8	-2.0	-2.0	-2.1	-2.4	-2.3	-2.1	-1.8	-2.2	-1.0	-2.2	-1.8	-2.2	0.4
Hair/balding pattern: Pattern 2	3.7	4.8	9.1	-1.7	-2.8	-2.4	-3.0	-1.7	-1.8	-1.6	-2.1	-1.7	-2.8	-2.6	-2.7	-2.2	-2.7	-1.4	-1.7	-1.4	-2.8	-0.3
Forced vital capacity (FVC), Best measure	3.3	12.1	19.0	-1.6	-3.9	-4.3	-3.6	-3.6	-4.2	-0.1	-3.5	-3.5	-3.6	-3.5	-3.0	-4.4	-3.6	-4.1	-3.4	-3.9	-3.7	-1.6
Type 2 Diabetes (T2D) (2012)	3.2	3.7	8.2	-0.9	-2.8	-2.2	-1.4	-2.2	-0.4	-0.4	-2.2	-1.6	-1.7	-2.6	-2.3	-2.2	-1.8	-2.3	-1.9	-1.2	-2.9	-1.2
Diabetes (mother)	2.8	3.6	11.6	-1.1	-3.4	-1.5	-2.9	-1.4	-1.0	-1.1	-1.5	-1.2	-1.9	-2.7	-2.4	-1.6	-1.9	-1.2	-0.9	-1.0	-3.3	-0.4
LDL Cholesterol	2.6	4.2	10.1	0.9	1.7	2.1	1.8	1.5	2.1	1.1	3.2	2.6	2.1	2.3	2.0	2.5	2.1	2.0	2.9	1.5	2.0	0.8
Heart disease (mother)	2.5	3.1	6.2	-0.7	-1.5	-2.5	-2.5	-2.0	-1.5	-2.3	-1.5	-1.5	-2.5	-1.6	-2.4	-1.4	-1.8	-1.1	-0.4	-0.1	-1.5	-2.2
Pain all over the body in last month	2.4	2.5	5.6	1.3	2.0	2.4	1.6	1.9	1.5	1.2	1.3	1.6	1.7	1.8	1.7	1.3	1.8	1.6	0.8	1.2	1.8	0.9
Bipolar Disorder (2018)	2.3	3.6	6.7	-1.5	-2.0	-2.0	-1.7	-1.4	-2.6	-2.2	-1.9	-1.9	-1.5	-2.3	-1.1	-2.0	-2.0	-1.8	-2.0	-1.9	-2.1	-1.5
Bipolar Disorder (2011)	2.2	2.1	5.6	-2.1	-1.7	-0.9	-0.9	-1.4	-2.4	-0.7	-1.0	-1.2	-0.8	-1.6	-0.4	-1.4	-0.9	-1.7	-1.7	-2.2	-1.8	-0.8
Lupus	2.2	3.3	7.8	0.2	2.3	1.8	2.7	0.8	2.8	0.8	2.5	2.2	1.9	2.2	1.6	2.2	1.4	0.9	1.8	0.9	2.2	-0.1
Average weekly fortified wine intake	2.2	2.6	6.5	-2.1	-1.3	-1.6	-0.6	-1.2	-2.5	-0.3	-1.9	-2.4	-1.4	-2.3	-0.6	-1.0	-1.6	-0.8	-1.9	-1.1	-2.0	-1.2
Pulse wave Arterial Stiffness index	2.2	2.6	6.8	-1.8	-0.7	-1.7	-1.6	-1.9	-2.3	0.2	-1.4	-2.1	-1.5	-1.4	-1.7	-1.1	-0.6	-2.0	-1.0	-1.8	-0.8	-2.6
Pain experienced in last month	2.2	3.7	9.0	-1.6	-2.2	-2.0	-3.0	-1.9	-1.9	-0.7	-2.2	-1.5	-1.9	-2.0	-1.7	-2.1	-1.9	-1.9	-2.1	-1.6	-2.3	-0.5
Breast cancer (self-reported)	2.1	2.5	6.8	-0.7	-1.2	-2.2	-1.1	-2.4	-1.1	-1.6	-1.6	-1.2	-1.5	-1.2	-1.4	-1.9	-1.8	-1.5	-1.6	-1.4	-1.0	-2.6
Number of live births	2.0	2.9	4.8	1.5	2.0	1.7	2.0	2.2	1.8	0.6	1.8	1.8	1.8	1.5	2.2	1.2	1.3	1.9	1.6	1.5	1.8	1.3
Standing height	2.0	20.2	48.3	0.0	-5.4	-7.0	-4.7	-6.1	-3.2	-1.5	-5.1	-3.5	-4.4	-4.2	-5.4	-5.1	-4.6	-5.7	-3.3	-4.0	-4.5	-2.0
Arm predicted mass (right)	2.0	10.3	23.0	0.1	-3.9	-4.8	-3.6	-3.5	-1.7	-1.7	-3.9	-2.8	-3.8	-3.5	-3.5	-3.1	-3.5	-4.5	-1.6	-2.0	-3.3	-2.2
Arm predicted mass (left)	2.0	10.2	21.8	0.2	-3.9	-4.7	-3.5	-3.4	-1.8	-1.5	-4.1	-2.9	-3.6	-3.6	-3.5	-3.2	-3.4	-4.3	-1.6	-1.9	-3.4	-2.5
Systolic Blood Pressure	1.9	9.6	18.6	-3.0	-3.0	-3.1	-2.7	-4.3	-3.2	-1.8	-2.4	-3.5	-2.9	-2.8	-4.1	-3.0	-2.4	-3.1	-3.1	-4.0	-2.8	-2.2
Had menopause	1.9	2.4	7.5	-0.7	-1.6	-1.5	-2.5	-1.5	-0.9	-2.7	-1.5	-1.5	-1.8	-1.4	-1.9	-1.5	-1.5	-1.0	-0.7	-1.3	-1.3	-1.2
Trunk fat-free mass	1.9	11.1	23.7	0.1	-4.1	-4.9	-3.5	-3.8	-2.1	-1.2	-4.2	-2.9	-3.6	-3.6	-3.5	-3.4	-3.3	-4.8	-1.9	-2.1	-3.5	-3.0
Trunk predicted mass	1.9	10.7	22.8	0.1	-4.0	-4.8	-3.5	-3.7	-2.0	-1.1	-4.1	-2.8	-3.5	-3.5	-3.4	-3.3	-3.3	-4.7	-1.8	-2.1	-3.5	-2.9
Knee pain experienced in last month	1.9	2.9	6.1	1.3	2.0	1.5	2.0	2.1	2.3	0.5	1.0	0.9	1.5	1.4	1.4	2.4	1.9	1.8	2.5	1.9	1.7	0.9
Arm fat-free mass (right)	1.8	9.4	21.5	0.2	-3.8	-4.6	-3.5	-3.3	-1.5	-1.6	-3.7	-2.6	-3.7	-3.2	-3.4	-3.1	-3.3	-4.3	-1.5	-1.9	-3.1	-1.9
Severe depression (siblings)	1.7	1.9	5.3	-2.3	-1.4	-1.3	-0.7	-0.3	-1.0	0.6	-2.0	-1.8	-1.2	-1.7	-0.4	-1.1	-0.8	-2.3	-1.6	-1.3	-1.5	-0.3
Illnesses of father: Heart disease	1.7	2.4	6.3	1.2	2.0	2.4	0.7	2.0	1.9	0.5	0.8	0.9	1.7	1.7	0.7	1.2	2.5	2.0	1.6	1.1	1.7	-0.7
Wears glasses or contact lenses	1.7	2.0	5.1	2.3	1.0	1.3	1.1	0.7	1.6	0.3	1.5	2.0	1.6	1.7	-0.0	0.9	1.7	1.9	1.3	1.2	1.4	-1.1
Arm fat-free mass (left)	1.7	8.7	19.5	0.3	-3.6	-4.4	-3.1	-3.2	-1.5	-1.5	-3.8	-2.6	-3.4	-3.3	-3.2	-3.0	-3.2	-4.0	-1.4	-1.8	-3.1	-2.2
Heel T-Score	1.6	12.6	24.5	2.0	3.1	3.8	2.6	4.8	2.3	3.2	3.0	3.4	3.6	3.1	3.0	3.5	5.0	4.7	3.4	4.5	3.4	3.5
Forced expiratory volume in 1-second (FEV1)	1.6	5.5	11.0	-0.9	-2.7	-2.9	-2.0	-2.0	-3.3	0.8	-2.7	-2.3	-2.1	-2.7	-1.2	-2.8	-2.2	-3.0	-2.3	-2.5	-2.6	-1.3
Pulse wave peak to peak time	1.6	1.8	6.0	1.8	0.4	1.3	1.3	1.5	2.2	-0.2	1.0	1.9	1.2	1.1	1.3	0.8	0.3	1.5	0.8	1.6	0.5	2.5
Whole body water mass	1.6	9.3	21.2	0.3	-3.6	-4.6	-3.3	-3.3	-1.7	-1.4	-4.1	-2.7	-3.5	-3.3	-3.1	-3.0	-3.1	-4.4	-1.3	-1.8	-3.1	-2.6
Supplements: Calcium	1.6	1.8	4.2	0.8	1.7	0.5	1.6	0.5	1.1	1.2	1.3	0.9	0.8	1.6	1.7	1.9	1.6	-0.2	2.0	0.8	2.1	0.3
Crohns Disease (2017)	1.5	3.3	15.6	0.3	1.4	1.8	3.2	1.8	0.7	1.5	1.3	1.1	1.8	1.1	2.4	0.5	1.2	2.9	-0.4	0.1	1.1	3.9
Primary Biliary Cirrhosis	1.5	2.1	4.6	2.0	0.9	2.0	1.3	2.1	1.4	1.3	1.1	1.6	1.8	1.4	1.4	0.9	1.4	0.3	1.4	2.0	0.9	-0.9
Medication: Co-codamol	1.5	1.8	4.0	-1.2	-1.9	-1.2	-0.9	-1.5	-0.6	-0.2	-1.2	-1.2	-1.0	-1.7	-1.4	-0.9	-1.8	-0.8	-1.2	-1.0	-2.0	-1.9
Medication: Lansoprazole	1.5	1.7	5.9	0.6	1.6	0.9	0.8	1.2	1.5	0.9	1.3	1.2	0.4	1.2	1.2	2.3	1.6	0.2	2.4	1.7	1.4	0.3
Whole body fat-free mass	1.5	8.6	19.9	0.5	-3.5	-4.5	-3.2	-3.2	-1.6	-1.4	-4.0	-2.6	-3.3	-3.1	-3.0	-2.8	-3.0	-4.3	-1.2	-1.6	-3.0	-2.5
Medication: Paracetamol	1.5	2.3	4.5	1.9	1.5	1.7	1.4	1.4	1.9	0.6	1.8	1.5	1.1	2.1	0.6	1.8	1.7	1.3	1.7	1.1	1.8	0.6
Height	1.4	26.6	70.1	1.0	-5.2	-8.4	-5.0	-7.1	-3.7	-1.8	-5.8	-3.9	-5.2	-4.5	-5.8	-5.8	-5.9	-6.9	-3.8	-3.7	-4.5	-4.6
Arm fat percentage (right)	1.4	5.4	10.1	3.2	2.5	2.5	2.7	3.1	2.9	0.3	1.4	1.9	2.1	1.9	2.3	2.6	1.9	1.8	2.9	2.6	2.3	1.1
Alcohol intake frequency.	1.4	3.2	7.0	2.0	0.8	2.5	1.7	1.6	2.7	0.3	1.9	1.9	2.3	1.4	2.2	1.8	1.8	2.2	1.2	2.0	1.0	1.0
Mineral and other dietary supplements	1.4	1.9	8.1	0.6	0.4	1.5	0.2	1.4	2.1	2.8	1.8	1.2	1.1	1.0	1.3	1.4	0.9	1.8	0.8	1.1	0.4	1.4
Ovarian Cancer	1.3	1.7	4.1	1.5	0.4	1.4	1.0	1.5	1.5	2.0	1.8	1.6	1.2	1.0	0.6	1.8	1.3	0.8	1.4	1.4	0.7	0.4
Smoking Status	1.3	3.2	6.1	-1.6	-2.1	-2.1	-2.4	-1.6	-1.9	-1.0	-1.8	-1.3	-2.3	-1.9	-1.6	-1.6	-2.5	-1.9	-1.0	-1.4	-2.0	-1.1
Hearing difficulty/problems: Yes	1.3	1.9	4.6	1.1	2.2	1.2	1.7	1.3	1.6	0.5	1.5	1.1	1.1	1.9	1.5	1.5	0.9	0.5	1.4	1.2	2.1	0.8
Financial difficulties in last 2 years	1.3	1.8	4.5	0.0	1.9	1.3	2.1	1.5	-0.0	0.5	0.9	1.0	1.3	1.3	1.3	1.8	1.9	0.6	1.6	1.2	1.8	0.2
Number of full sisters	1.3	1.6	3.0	-1.7	-1.6	-1.7	-0.7	-1.1	-1.0	-0.3	-1.2	-1.5	-1.2	-1.7	-1.0	-1.2	-1.5	-0.9	-1.1	-0.7	-1.7	-1.2
Leg fat-free mass (right)	1.3	6.7	16.0	0.5	-3.0	-4.0	-2.9	-2.6	-1.3	-1.5	-3.6	-2.5	-3.2	-2.9	-2.5	-2.3	-2.6	-3.8	-0.8	-1.4	-2.6	-2.1
Leg predicted mass (right)	1.3	7.1	16.8	0.3	-3.1	-4.1	-2.9	-2.7	-1.4	-1.6	-3.6	-2.6	-3.2	-3.0	-2.5	-2.4	-2.7	-3.8	-0.9	-1.5	-2.7	-2.1
Multivitamins +/- minerals	1.2	1.5	5.7	-0.4	-0.7	-1.5	0.1	-1.0	-0.9	-0.7	-1.1	-1.3	-1.0	-0.8	-0.5	-1.2	-1.5	-2.4	-1.4	-1.6	-0.6	-2.0
Headache pain in last month	1.2	2.1	6.2	0.7	1.5	1.4	1.8	1.2	1.6	1.5	2.5	1.5	1.1	1.8	1.1	2.0	1.1	1.0	1.6	0.9	1.7	0.4
Mean time to correctly identify matches	1.2	2.3	5.4	2.3	1.2	2.1	0.7	1.8	1.8	1.4	1.1	1.8	1.9	1.8	1.2	0.2	1.2	1.8	0.0	1.4	1.4	1.1
Basal metabolic rate	1.2	6.9	16.1	0.8	-3.1	-4.0	-2.7	-2.7	-1.3	-1.4	-3.7	-2.4	-3.0	-2.9	-2.7	-2.5	-2.7	-3.9	-1.0	-1.3	-2.7	-2.2
Coronary Artery Disease (CAD)	1.1	1.4	4.5	0.1	0.8	1.3	1.4	0.0	0.5	0.1	2.1	1.3	1.9	0.9	1.0	1.7	1.5	1.1	1.4	0.5	0.8	-0.6
Crohns Disease (2012)	1.1	1.8	5.8	1.1	0.7	1.9	1.8	1.4	1.2	0.4	1.3	1.2	1.5	1.1	1.3	0.9	1.4	2.2	-0.1	0.8	0.8	2.4
Systolic blood pressure, automated reading	1.1	3.2	7.2	-0.9	-1.3	-1.6	-0.8	-2.4	-2.3	-2.2	-1.5	-2.5	-1.0	-1.8	-2.1	-1.7	-1.4	-0.7	-1.9	-2.1	-1.5	-2.7
Medication for hormone replacement therapy	1.1	1.3	3.2	-0.5	-0.9	-1.1	-1.4	-0.8	-1.6	-1.2	-1.8	-1.4	-1.3	-1.4	-0.6	-1.1	-0.7	-0.9	-1.3	-0.7	-1.1	-0.4
Medication: Levothyroxine sodium	1.1	1.8	4.4	1.3	1.2	1.4	2.0	1.2	1.2	1.6	1.7	0.4	1.8	1.2	1.4	1.2	0.8	0.0	1.3	0.7	1.0	-2.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.6	8.2	0.2	-2.5	-2.4	-1.7	-1.4	-2.9	1.2	-1.8	-1.7	-1.6	-2.0	-1.1	-2.6	-2.0	-2.3	-1.9	-1.9	-2.3	-0.5
Glaucoma (self-reported)	1.1	1.3	3.9	0.5	1.4	1.4	2.0	1.4	0.5	1.6	0.7	1.4	1.7	1.0	1.2	-0.2	0.7	1.1	0.2	0.8	1.0	0.3
Exposure to tobacco smoke outside home	1.1	1.5	3.0	-1.3	-1.1	-1.7	-1.2	-1.6	-0.6	0.2	-1.0	-1.7	-1.4	-1.0	-1.3	-1.3	-0.9	-1.3	-0.8	-1.6	-1.0	-0.9
Comparative height size at age 10	1.1	6.2	20.4	0.2	-2.6	-3.5	-2.4	-2.9	-2.1	0.1	-3.2	-1.6	-2.4	-2.2	-2.8	-2.7	-2.1	-4.5	-2.0	-1.8	-2.3	-2.2
Arm fat percentage (left)	1.1	4.4	8.8	3.0	2.2	2.1	2.4	2.8	2.9	0.1	1.4	1.7	1.6	1.8	1.9	2.4	1.7	1.4	2.7	2.3	2.2	1.0
Reaction Time	1.0	1.8	3.7	1.9	1.3	1.9	0.7	1.6	1.6	1.5	0.6	1.6	1.9	1.5	1.3	-0.4	1.1	1.8	-0.2	0.9	1.3	0.8
Lung FVC	1.0	5.2	17.8	-2.5	-2.5	-1.6	-2.3	-1.7	-4.2	-1.6	-1.8	-2.7	-2.2	-2.4	-1.4	-2.3	-1.8	-1.2	-1.9	-2.8	-2.4	-2.4
Age when periods started (menarche)	1.0	2.4	14.4	2.0	0.4	1.2	1.2	1.8	0.3	1.5	0.7	0.7	1.5	0.5	1.0	1.1	1.4	2.7	1.1	1.7	0.6	3.8
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	4.2	0.6	2.0	0.8	-0.1	1.5	0.5	-1.7	-0.1	0.6	0.2	1.3	0.5	0.2	1.4	1.0	0.7	1.1	1.8	-0.2
Serious illness, injury or assault to yourself	1.0	1.2	4.9	-1.1	-1.0	-0.8	-0.3	-1.2	-0.8	-0.0	-0.9	-1.7	-0.5	-1.4	-0.7	-0.8	-1.0	-1.4	-1.4	-0.6	-1.1	-2.2
Alcohol usually taken with meals	1.0	1.6	3.0	1.4	1.2	1.2	1.1	1.5	1.0	1.7	1.4	1.6	0.7	1.6	1.0	1.0	1.4	0.3	1.0	1.0	1.7	1.5
Impedance of arm (right)	1.0	4.5	8.4	1.3	2.8	2.4	2.9	1.6	1.4	1.3	2.1	1.9	2.8	2.5	2.2	1.8	2.0	2.6	1.2	1.0	2.5	2.7
Worrier / anxious feelings	1.0	1.8	4.8	0.9	1.2	1.2	1.0	1.0	1.6	-0.6	1.6	1.7	1.0	1.7	1.0	1.2	1.3	1.4	1.7	0.8	1.5	2.2
Tense / ‘highly strung’	1.0	1.6	4.7	-1.3	-1.6	-1.6	-1.4	-1.8	-0.1	0.1	-0.7	-0.5	-1.8	-0.9	-1.3	-1.3	-1.5	-2.2	-0.5	-1.1	-1.0	-1.1
Medication: Paracetamol	1.0	1.6	4.1	1.2	1.2	1.6	0.9	1.0	1.8	0.0	2.0	1.5	0.8	1.9	0.2	1.6	1.2	0.9	1.4	0.4	1.5	0.8
Birth weight	1.0	2.1	4.9	-1.8	-1.7	-0.8	-0.5	-0.9	-2.1	-0.9	-1.5	-1.7	-0.5	-2.2	-0.4	-1.2	-1.7	0.1	-1.7	-1.4	-2.1	-1.8
Worry too long after embarrassment	1.0	1.6	4.6	1.0	1.1	1.3	0.6	1.6	2.1	0.6	1.6	1.3	0.5	1.4	1.0	1.5	0.8	0.0	1.6	1.0	1.4	1.9
Medication for pain relief, constipation, heartburn	1.0	1.7	4.0	-0.6	-1.7	-1.7	-0.9	-0.9	-1.6	0.2	-1.9	-1.4	-0.9	-2.0	0.5	-1.5	-1.8	-0.6	-1.5	0.6	-1.9	0.4
Migraine (self-reported)	1.0	1.3	4.4	1.1	1.2	-0.1	1.0	-0.2	1.6	-0.5	2.1	1.9	0.2	1.8	-0.2	0.2	0.4	0.6	1.8	-0.1	1.7	0.2
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	5.3	-0.7	-1.2	-2.3	-0.8	-1.9	-1.1	-0.9	-1.5	-1.3	-1.3	-1.1	-1.3	-2.0	-1.7	-1.6	-1.9	-1.6	-1.1	0.3
Ever smoked	1.0	1.8	3.9	-1.0	-1.1	-2.0	-1.8	-1.9	-1.9	-1.7	-0.9	-0.9	-1.7	-0.8	-1.7	-1.1	-1.4	-0.6	-0.6	-1.4	-0.9	-0.7
Unable to work because of sickness or disability	1.0	1.3	3.2	-1.8	-1.6	-1.1	-0.5	-0.9	-1.2	-0.1	-0.8	-1.2	-0.7	-1.5	-0.5	-0.5	-0.9	-1.3	-1.0	-1.3	-1.7	-1.5
Sensitivity / hurt feelings	0.9	1.6	4.7	0.9	0.6	1.7	-0.0	1.7	1.9	0.5	1.9	2.2	0.6	1.6	0.5	0.7	0.7	-0.2	1.6	1.0	1.0	1.5
Fed-up feelings	0.9	1.6	5.5	0.0	0.7	1.7	-0.3	1.2	1.4	-1.2	1.9	2.1	0.3	1.9	-0.2	1.3	1.1	0.3	1.3	0.4	1.2	2.3
Qualifications: CSEs or equivalent	0.9	1.1	3.5	-0.5	1.3	1.6	1.2	1.0	0.7	0.2	0.5	0.6	1.6	0.6	1.1	1.6	1.3	1.9	0.6	0.9	0.7	0.1
Supplements: Glucosamine	0.9	1.2	5.5	0.2	-1.0	-1.2	-0.2	-1.1	-2.3	-1.4	-1.7	-1.3	-0.7	-1.2	-1.5	-1.2	-0.2	0.1	-0.7	-0.2	-1.0	-0.9
Past tobacco smoking	0.9	1.7	3.6	1.0	1.1	1.8	1.7	1.9	1.6	1.9	0.7	0.5	1.7	0.6	1.7	1.2	1.4	0.8	0.4	1.2	0.8	0.8
Length of working week for main job	0.9	1.0	2.7	0.6	0.6	1.1	1.3	1.2	1.1	1.7	0.6	0.9	1.5	0.8	1.3	1.2	1.1	0.5	1.0	0.1	0.9	-0.5
Medication for cholesterol, blood pressure or diabetes	0.9	1.6	3.9	-0.6	-1.3	-1.2	0.1	-0.6	-2.0	-1.5	-2.0	-1.1	-0.1	-1.8	0.8	-1.6	-1.7	-0.9	-1.4	-0.6	-1.6	-0.3
Eye problems/disorders: None of the above	0.9	1.0	4.2	0.4	1.0	1.5	1.5	1.2	-0.2	1.2	0.3	-0.0	1.4	0.4	2.0	0.7	1.1	0.9	0.2	0.3	0.8	1.1
Osteoporosis (self-reported)	0.9	1.1	4.1	0.9	-0.2	0.1	0.7	-0.3	1.7	1.7	2.0	1.8	0.4	1.2	0.6	0.7	0.1	0.3	1.6	0.6	0.5	-0.5
Eye problems/disorders: Glaucoma	0.9	1.0	3.0	0.7	1.3	0.9	1.7	1.1	1.1	1.4	0.8	1.5	1.1	1.4	0.7	-0.6	0.7	0.2	0.1	0.5	1.2	0.3
Supplements: Fish oil (including cod liver oil)	0.9	1.1	6.6	0.2	-0.4	-1.1	-0.4	-0.6	-1.7	-2.6	-1.7	-1.1	-0.9	-1.1	-1.0	-1.2	-0.6	-0.6	-0.2	-0.1	-0.4	-0.7
Age started oral contraceptive pill	0.9	1.2	3.8	1.9	0.8	1.0	1.1	1.3	0.2	-0.1	0.5	0.7	1.4	0.6	0.6	0.5	1.4	1.9	1.5	1.3	0.8	-0.2
Breast Cancer	0.8	2.0	3.8	-1.6	-1.0	-1.0	-0.9	-1.3	-1.9	-1.3	-1.6	-1.7	-0.7	-1.9	-1.3	-1.3	-1.5	-1.0	-1.6	-1.6	-1.7	-0.8
Age at First Birth	0.8	1.2	4.0	1.4	0.4	1.3	0.7	2.0	-0.2	0.9	0.4	1.0	1.1	0.3	0.4	0.6	1.4	1.9	0.6	1.1	0.3	1.9
Rheumatoid Arthritis	0.8	1.1	2.7	1.1	1.0	1.0	0.4	1.0	1.6	1.4	0.9	1.4	0.9	1.4	0.4	0.6	0.8	-0.9	1.1	1.1	1.2	-1.1
Number of treatments/medications taken	0.8	1.4	4.5	0.6	1.6	1.1	0.9	0.4	1.1	-0.2	1.6	1.1	0.8	1.6	-0.5	1.2	1.4	0.2	1.6	0.4	1.6	-2.1
Ever had hysterectomy (womb removed)	0.8	0.9	3.2	0.8	0.9	0.9	0.7	0.5	1.8	-0.6	1.1	1.3	0.8	1.2	1.3	0.4	0.8	-0.2	1.0	0.1	1.1	0.7
Impedance of leg (right)	0.8	3.7	10.7	1.2	2.3	2.2	2.3	1.3	1.5	1.4	2.0	2.0	2.6	2.3	1.4	1.1	1.6	2.4	0.4	0.9	2.1	3.3
Leg fat-free mass (left)	0.8	4.4	11.6	1.0	-2.4	-3.4	-2.3	-2.1	-0.8	-1.3	-3.2	-1.8	-2.5	-2.3	-1.9	-1.8	-2.0	-3.2	-0.1	-0.8	-1.9	-1.8
Leg predicted mass (left)	0.8	4.4	11.5	1.0	-2.3	-3.4	-2.3	-2.1	-0.8	-1.4	-3.2	-1.9	-2.5	-2.3	-1.9	-1.8	-2.0	-3.2	-0.1	-0.8	-1.9	-1.9
Noisy workplace	0.8	1.0	3.1	0.7	0.6	0.1	1.7	0.4	0.2	0.1	1.6	0.7	0.7	0.6	0.9	1.5	0.5	1.8	1.3	1.0	0.5	1.0
Depression (self-reported)	0.8	1.0	3.6	-0.5	-0.9	-0.9	-1.5	-0.3	-0.5	0.6	-0.9	-0.9	-1.5	-0.9	-1.6	-0.5	-0.4	-1.9	0.1	-0.7	-0.8	-1.2
Impedance of arm (left)	0.8	3.6	6.7	1.3	2.4	2.2	2.5	1.4	1.5	1.0	2.1	1.9	2.3	2.5	1.7	1.4	1.8	2.1	0.9	0.5	2.4	2.6
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	3.3	-0.9	-1.0	-0.6	-0.9	-0.2	-1.2	1.4	-1.1	-0.7	-0.8	-0.8	-1.4	-1.3	-0.1	-1.8	-1.6	-0.5	-1.1	-1.7
Medication: Ventolin 100micrograms inhaler	0.8	1.0	3.1	-1.8	-0.6	-1.1	-0.9	-1.5	0.5	-1.2	-0.7	-0.8	-0.9	-0.7	-1.0	-0.8	-1.1	-0.7	-0.9	-1.3	-0.7	-0.6
Body fat percentage	0.8	3.3	10.2	3.2	1.9	1.4	2.0	2.2	2.8	-0.2	0.9	1.4	1.2	1.6	1.0	1.8	1.1	1.4	2.2	2.1	1.9	1.7
Long-standing illness, disability or infirmity	0.8	1.3	5.7	-1.1	-0.7	-1.0	-0.6	-2.0	-0.0	-1.2	-0.3	-0.2	-1.0	-0.3	-2.2	-0.8	-0.5	-0.7	-0.1	-1.1	-0.5	-2.4
Medication for cholesterol	0.8	1.2	4.5	1.0	0.4	1.0	0.5	1.6	-0.1	1.0	0.3	0.5	1.3	0.0	1.0	0.8	0.9	2.1	0.5	1.7	0.0	2.1
Heart disease (siblings)	0.8	1.0	4.4	1.4	0.9	2.1	0.6	0.4	1.1	-0.5	0.7	1.0	1.4	1.0	0.5	0.4	1.6	1.1	0.7	0.6	0.7	-0.7
Hypothyroidism (self reported)	0.7	1.6	3.2	1.8	1.3	1.1	1.5	0.9	1.7	1.2	1.5	0.6	1.2	1.2	0.5	1.1	1.5	0.3	1.7	1.1	1.2	-1.4
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	3.4	-1.8	-0.6	-1.3	-0.4	-1.4	0.1	0.3	-0.2	-0.6	-1.4	-0.5	-0.6	0.6	-0.4	-1.4	0.8	0.2	-0.4	-1.7
Trunk fat percentage	0.7	2.6	9.9	3.1	1.6	1.0	1.7	1.9	2.6	-0.5	0.7	1.2	0.9	1.4	0.7	1.6	0.8	1.2	2.0	1.9	1.7	1.8
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	4.2	0.6	0.6	0.9	0.5	1.3	0.5	1.2	1.3	1.2	0.3	0.6	0.5	2.0	1.3	-0.0	1.8	1.2	0.6	1.4
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	2.4	-1.2	-0.5	-1.0	-0.5	-0.8	-0.7	-0.4	-0.8	-1.3	-0.8	-0.7	-0.3	-1.1	-1.1	-1.1	-0.6	-1.1	-0.5	-1.5
Leg fat percentage (right)	0.7	2.7	7.9	2.8	1.8	1.5	1.5	2.1	2.6	-0.5	0.7	1.3	1.1	1.4	0.9	1.5	1.2	1.2	2.0	2.0	1.7	1.0
Health satisfaction	0.7	0.9	4.4	-2.1	-1.0	-1.4	-0.5	-1.1	-0.0	-0.3	-0.4	-1.5	-1.3	-1.1	-0.1	-0.1	-0.7	-0.6	-0.4	-1.0	-1.0	-0.2
Mouth/teeth dental problems: Loose teeth	0.7	0.8	2.1	1.1	0.3	0.7	0.7	0.6	-0.0	1.5	0.7	0.9	1.2	0.5	0.6	1.2	1.3	0.9	1.4	1.4	0.4	-0.0
Age at last live birth	0.7	1.0	2.9	-0.0	1.4	0.5	1.6	0.7	0.9	1.6	1.0	0.7	0.8	1.0	1.7	0.9	0.5	0.7	0.0	0.5	1.2	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	4.0	0.2	-0.9	-0.8	-1.1	-1.1	-1.3	-0.2	-0.6	-0.2	-0.4	-0.7	-0.6	-2.0	-1.3	0.3	-1.0	-0.4	-0.8	0.1
Medication: Bendroflumethiazide	0.7	1.0	3.1	-0.2	0.3	0.5	0.1	-1.0	1.4	-0.0	1.8	1.2	0.1	1.4	-0.9	0.9	1.6	0.9	1.4	-0.5	1.2	-0.2
Number of operations (self-reported)	0.7	1.0	1.7	-0.1	1.1	1.1	1.3	1.3	1.1	0.8	1.2	1.1	0.8	1.2	1.1	0.8	0.9	-0.5	1.1	0.8	1.2	-0.1
Intelligence (Savage-Jansen 2018)	0.6	1.9	6.7	-1.1	-1.6	-1.0	-2.6	-1.1	-0.7	-1.5	-1.3	-1.3	-1.9	-1.3	-1.9	-1.2	-1.0	-0.8	-1.1	-0.9	-1.5	-1.1
Ulcerative Colitis (UC)	0.6	1.2	2.7	-1.5	-1.1	-1.1	-0.3	-1.0	-1.3	0.1	-1.1	-1.2	-0.8	-1.4	0.1	-1.5	-1.4	0.2	-1.6	-0.9	-1.5	0.5
Prostate Cancer	0.6	0.8	3.4	-0.5	1.3	0.0	1.6	-0.2	0.4	0.9	0.1	0.0	-0.2	1.0	0.0	-0.5	-0.5	-1.9	-1.1	-1.4	1.4	0.2
Blood Platelet Count	0.6	6.9	18.5	-0.0	3.3	3.3	2.8	2.2	2.7	2.3	4.2	2.5	1.5	4.3	2.0	1.7	1.9	0.8	1.4	-1.2	4.1	2.9
Respiratory disease	0.6	1.3	4.4	-1.2	-0.6	-1.6	-0.5	-1.4	-0.8	-1.3	-1.6	-2.1	-1.2	-1.5	-0.5	-0.7	-1.5	-0.2	-1.1	-0.5	-1.1	-0.7
Type 2 Diabetes (T2D) (2018)	0.6	1.2	6.7	0.3	-1.1	-1.2	-1.2	-0.9	1.5	-1.1	-1.1	-0.1	-1.3	-0.6	-2.6	-1.3	-0.8	0.3	-0.2	0.2	-0.8	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	2.7	-1.6	-0.7	-0.8	-0.1	-1.1	-0.8	-0.4	-0.5	-0.8	-0.7	-1.2	-0.6	-0.4	-1.0	-1.6	-1.0	-0.8	-1.1	-1.2
Neuroticism score	0.6	1.3	4.7	0.0	0.5	1.0	-0.2	0.8	1.4	-0.0	1.7	1.9	0.0	1.4	-0.0	1.3	1.2	0.0	1.7	0.9	1.0	2.2
Birth weight of first child	0.6	1.1	2.7	-0.2	-0.8	-0.8	-0.5	-1.5	-1.0	-0.9	-1.2	-0.7	-0.8	-0.8	-1.7	-1.6	-0.7	-0.6	-1.2	-1.2	-0.9	-1.4
Wheeze or whistling in the chest in last year	0.6	1.2	2.9	-1.4	-0.5	-1.7	-0.3	-1.7	-0.3	-1.6	-0.8	-0.9	-1.2	-1.1	-0.5	-0.2	-1.6	-0.7	0.3	-0.7	-0.6	-1.7
Medication: Blood pressure	0.6	1.1	4.0	-0.3	0.8	1.0	0.1	-0.0	1.6	1.1	2.0	1.1	0.3	1.3	-0.4	1.8	1.2	0.4	1.2	-0.1	1.1	0.6
Eye problems/disorders: Cataract	0.6	0.7	1.7	0.4	0.5	-0.8	-1.2	-0.1	1.0	-1.0	0.3	0.5	-1.2	0.6	-1.3	0.4	-0.4	-0.8	1.2	0.5	0.7	-1.1
Osteoarthritis (self-reported)	0.6	0.7	2.3	-0.1	-0.4	0.7	1.5	0.4	0.8	-0.3	1.3	1.2	0.9	0.3	0.0	1.2	0.7	0.5	1.5	0.1	-0.1	-1.3
Number of self-reported non-cancer illnesses	0.6	1.0	4.4	0.5	0.5	0.3	0.3	0.4	2.1	-0.3	1.0	1.4	0.1	0.8	-0.4	1.1	1.0	0.1	2.0	1.1	0.8	-1.1
Cholesterol lowering medication	0.6	0.9	3.9	-0.4	-0.6	-1.0	-0.8	-1.3	1.1	-1.6	0.4	0.1	-1.0	0.2	-1.5	-0.2	-0.5	-0.9	1.2	-0.6	-0.0	-2.0
Impedance of whole body	0.6	3.0	11.3	0.9	2.0	1.9	2.1	1.0	1.2	1.0	2.1	1.7	2.2	2.1	1.2	1.0	1.4	2.3	0.3	0.5	1.9	3.4
Neuroticism (2016)	0.5	0.7	2.3	0.9	0.5	1.3	0.5	1.5	1.3	0.1	0.5	1.1	0.6	1.0	0.6	0.1	1.0	0.1	1.0	0.0	0.8	0.4
Waist Hip Ratio (WHR)	0.5	2.1	9.1	1.1	1.3	1.0	0.4	1.2	3.0	2.0	1.3	1.6	0.5	1.7	-0.6	1.8	1.2	0.9	1.1	2.2	1.3	0.4
Frequency of depressed mood in last 2 weeks	0.5	0.8	2.3	-0.7	-0.5	-0.7	-1.5	-0.4	-0.8	-1.5	-1.0	-0.6	-1.3	-0.6	-1.5	-0.5	-0.4	-1.2	-0.2	-0.5	-0.6	0.0
Waist circumference	0.5	2.0	8.0	2.8	1.3	0.5	1.0	1.7	2.5	0.4	-0.2	0.9	0.5	0.8	0.6	1.4	0.9	0.5	2.2	2.6	1.1	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.0	3.6	0.4	0.4	1.3	0.6	1.5	0.2	1.3	1.0	0.8	1.0	0.7	-0.1	1.1	1.2	1.9	0.6	1.2	0.5	1.2
Allergy	0.5	1.1	2.7	0.5	0.9	1.5	1.1	0.7	0.9	0.4	1.6	1.0	1.3	1.3	0.2	1.2	1.5	1.0	1.0	0.6	1.2	0.4
Diabetes (self-reported)	0.5	0.7	4.2	0.7	-0.2	-0.1	-0.8	-0.3	1.7	0.4	-0.3	0.4	-0.3	0.1	-2.1	-0.3	1.1	1.6	0.7	1.0	-0.1	0.4
Medication: Simvastatin	0.5	0.7	2.5	0.4	0.2	0.2	-1.2	0.2	1.4	-0.9	0.9	1.0	-0.5	0.9	-1.6	0.4	0.7	0.7	1.3	0.6	0.5	-0.8
Qualifications: A levels/AS levels or equivalent	0.5	1.1	2.6	-0.7	-0.6	-1.2	-1.1	-0.9	-1.0	0.4	-0.9	-1.0	-1.6	-0.7	-1.5	-0.8	-0.5	-1.6	-1.2	-1.2	-0.5	-1.5
Medication: Cholesterol lowering	0.5	0.8	2.2	0.5	0.8	0.7	-1.1	0.3	1.5	0.1	1.4	0.7	-0.6	1.1	-1.1	1.0	1.1	0.9	1.2	0.3	0.8	-0.2
Prospective memory result	0.5	0.6	2.7	0.8	-0.3	0.6	0.7	0.4	0.8	-0.3	1.0	1.2	0.7	0.6	0.9	0.6	0.1	0.9	0.6	0.7	0.1	1.6
Hair/balding pattern: Pattern 4	0.5	1.2	3.0	-0.4	-1.3	-1.7	-1.7	-1.6	0.9	-1.6	-0.8	-0.9	-1.2	-0.8	-0.8	-0.9	-1.5	-0.2	-0.5	-0.5	-1.1	0.3
Loud music exposure frequency	0.5	0.5	1.8	0.7	1.3	0.7	0.9	0.9	-0.3	-0.7	-0.2	0.0	0.4	0.5	0.6	-0.1	0.3	0.9	-0.3	0.5	0.9	1.3
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	2.8	-0.2	0.6	-0.7	0.8	0.0	-1.3	-1.1	-1.4	-1.0	0.3	-0.7	0.5	-0.1	-0.1	0.3	-0.2	0.9	0.1	-1.7
Hypothyroidism/myxoedema (self-reported)	0.5	1.1	5.1	0.9	0.9	1.1	1.8	0.7	0.9	0.5	1.3	-0.1	1.6	0.7	0.8	0.8	0.6	0.0	0.9	0.4	0.5	-2.3
Medication: Allopurinol	0.5	0.7	1.9	1.2	0.6	0.8	-0.0	1.2	0.7	0.4	0.8	0.9	0.7	0.9	0.5	0.8	0.8	0.4	0.9	1.4	0.7	-0.0
Medication: Aspirin	0.5	0.7	3.7	-0.0	1.1	0.9	-0.5	0.3	-0.2	-0.6	-0.2	-0.2	0.4	0.7	-1.1	0.3	1.8	-0.0	0.4	-0.1	1.0	-1.9
Smoking status: Previous	0.5	0.7	2.2	-0.1	-0.6	-0.9	-1.3	-1.0	-0.9	-1.4	-0.3	0.1	-1.2	0.1	-1.5	-1.1	-0.9	-0.8	-0.0	-1.0	-0.2	-0.2
Average weekly red wine intake	0.5	0.8	2.3	-1.5	-0.2	-1.0	-0.1	-0.3	-1.4	-0.5	-1.4	-1.2	-1.0	-0.9	-0.3	-0.9	-0.4	-1.2	-0.7	-1.0	-0.5	-0.1
Commuting to job workplace: Walk	0.5	0.6	2.0	-1.1	0.4	-0.4	-0.8	-1.0	0.1	-0.7	-0.2	-0.3	-1.1	0.0	-0.6	-0.6	-0.4	-1.1	0.1	-1.4	0.5	-1.2
Smoking status: Current	0.5	0.8	1.8	-1.0	-1.0	-1.0	-0.7	-0.9	-1.2	-0.1	-1.0	-0.8	-0.7	-1.2	-0.5	-0.5	-1.3	-0.5	-0.7	-0.5	-1.1	-1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	7.9	0.5	0.2	0.5	0.7	1.0	0.5	2.8	1.5	0.6	0.5	0.4	1.4	0.8	0.7	0.7	1.1	0.4	0.3	-0.1
Medication: Lisinopril	0.5	0.6	2.7	-1.0	-0.3	-0.5	-1.6	-0.9	0.2	0.2	-0.3	-0.0	-1.4	-0.4	-1.6	0.9	0.5	-0.5	0.9	0.6	-0.2	-0.2
Alcohol drinker status: Never	0.5	0.6	2.8	0.7	0.9	1.1	0.7	0.5	0.8	0.5	0.3	0.5	1.0	0.4	1.7	0.8	1.0	0.3	0.1	1.0	0.7	-0.5
Fractured/broken bones in last 5 years	0.5	0.7	3.1	0.6	-1.1	-0.7	0.5	-0.7	0.5	-0.2	-0.6	-1.0	-0.2	-0.7	0.1	-1.0	-1.1	-1.8	-0.9	-0.8	-0.9	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.8	0.2	1.3	0.4	1.7	-0.1	0.2	-0.4	0.7	0.3	0.4	1.1	0.1	0.1	1.0	-0.3	0.4	-0.8	1.3	-0.5
Alzheimer’s Disease (in mother)	0.4	0.5	2.7	-0.2	0.2	0.3	-0.3	-0.4	0.9	-0.3	0.9	0.6	-0.1	0.8	-0.7	0.9	0.5	-0.9	0.6	-0.9	0.7	1.7
Alzheimer’s Disease (in father)	0.4	0.4	1.4	-0.7	-1.2	-0.1	-1.0	-0.6	-0.1	-1.2	0.4	0.2	-0.4	-0.6	-0.6	-0.0	-0.8	0.1	0.3	-0.6	-1.2	-0.1
Irritable Bowel Disease (IBD)	0.4	1.1	6.7	-1.0	-0.3	0.1	1.5	0.0	-0.2	1.0	0.2	-0.1	0.3	-0.3	1.0	-0.9	-0.5	1.8	-1.5	-0.7	-0.6	2.6
Verbal and Numeric Reasoning (VNR)	0.4	0.9	2.7	-0.5	-0.6	-0.5	-1.6	-0.3	-0.8	-0.7	-1.4	-1.2	-1.1	-0.6	-1.0	-1.2	-0.6	-0.5	-1.2	-0.6	-0.5	-1.3
Body Mass Index (BMI) (2010)	0.4	0.6	3.0	0.0	0.2	-0.3	-0.3	0.1	1.1	-0.8	0.7	0.6	-0.6	0.6	-0.4	1.1	0.2	-0.7	1.5	0.7	0.4	-1.7
Fasting Glucose	0.4	0.5	2.3	1.5	0.5	0.8	-0.1	0.7	0.4	-0.2	0.4	0.5	0.3	0.9	-0.2	0.1	1.1	0.2	1.2	0.8	0.7	0.1
Blood White Count	0.4	2.7	9.4	-0.6	2.1	1.5	1.1	1.1	2.8	1.2	1.6	1.8	1.0	1.9	1.8	1.2	1.0	1.8	0.9	0.5	2.0	3.1
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.7	0.5	0.9	0.1	0.6	-0.2	1.0	0.3	1.0	0.4	0.0	1.3	-0.8	0.5	1.1	0.3	0.6	-0.1	1.0	0.5
Relative age voice broke	0.4	0.6	2.4	0.8	0.7	0.5	0.7	0.8	0.6	1.2	0.5	0.4	0.8	0.8	0.3	0.3	0.5	1.5	0.6	0.6	0.9	1.0
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	2.7	-1.6	-0.2	-0.7	-0.1	-0.9	0.2	-0.7	-0.3	-0.2	-0.8	-0.5	0.7	0.4	-0.3	-0.9	0.6	-0.6	-0.2	-0.0
Impedance of leg (left)	0.4	1.9	10.9	0.7	1.2	1.4	1.7	0.7	1.1	1.4	1.7	1.3	1.7	1.5	0.3	0.5	0.7	1.7	-0.6	0.3	1.1	3.3
Had other major operations	0.4	0.5	2.3	0.7	0.9	0.9	1.3	0.9	0.6	0.5	-0.2	0.0	1.3	0.3	1.5	0.0	0.5	-0.2	-0.0	0.7	0.5	0.1
Qualifications: None of the above	0.4	0.9	4.5	0.4	1.1	1.2	0.9	0.7	0.4	-2.1	0.6	0.8	0.8	0.6	1.2	0.5	0.3	1.4	0.8	0.3	0.8	1.2
Mouth/teeth dental problems	0.4	0.6	1.7	-1.3	-0.9	-0.7	-0.7	-0.2	0.8	1.1	0.5	0.0	-1.2	-0.2	-0.8	-0.4	-0.7	-1.3	-0.5	-1.1	-0.6	0.3
Illnesses of siblings	0.4	0.6	2.5	-0.7	-0.7	-1.6	-0.5	-0.7	-1.0	-0.3	-0.6	-0.6	-1.2	-0.8	-0.2	-0.2	-1.1	-0.4	-0.5	-0.7	-0.6	0.9
Weight	0.4	2.2	5.3	1.7	-1.5	-2.3	-1.1	-1.1	0.1	-1.3	-2.3	-1.2	-1.7	-1.5	-1.6	-1.1	-1.5	-2.3	0.2	-0.3	-1.2	-1.4
Falls in the last year	0.4	0.6	2.9	0.9	-0.3	0.4	-0.2	0.5	1.7	1.3	0.6	0.8	0.4	0.5	0.2	0.9	0.7	-0.4	1.0	0.9	-0.1	-0.3
Lung cancer (father)	0.4	0.4	3.1	1.1	-0.4	0.3	0.3	-0.1	-0.4	1.8	-0.0	0.2	0.8	-0.2	0.3	-0.0	0.4	0.1	-0.4	0.6	-0.2	1.2
Pulse wave reflection index	0.4	0.5	2.7	-1.6	-0.1	-0.4	-0.4	-0.7	-1.4	-0.3	-1.1	-0.9	-0.3	-0.8	-0.4	-0.2	-0.2	-0.3	-0.4	-0.6	-0.3	-0.5
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.4	-1.0	-0.3	-0.7	-0.8	-1.0	0.2	0.0	-0.4	0.1	-0.9	-0.2	-0.6	-0.9	-0.6	-0.5	-0.4	-0.5	-0.3	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	1.1	0.1	-0.8	-0.9	-1.0	-0.2	-0.8	0.4	-0.6	-0.2	-0.8	-0.8	0.0	-0.4	-0.8	-0.8	0.3	-0.1	-0.8	0.9
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	2.2	-1.2	-0.0	-0.1	-0.3	-0.4	-0.9	-0.1	-0.3	-1.0	-0.2	-0.4	-0.1	-0.6	-0.1	-0.7	-1.0	-1.1	-0.5	-1.5
Commuting to job workplace: Car/motor vehicle	0.4	0.5	2.7	0.3	-0.5	-0.8	1.0	-0.4	-1.6	-0.6	-0.4	-0.7	0.3	-0.7	0.2	-0.4	-0.5	0.7	-0.8	0.5	-0.6	-0.9
Supplements: Vitamin C	0.4	0.5	1.8	1.1	0.3	0.1	-0.1	-0.2	0.8	0.7	1.0	0.8	-0.3	1.3	-0.4	0.4	0.6	-0.6	1.0	0.2	1.0	0.3
Loneliness, isolation	0.4	0.5	2.0	1.4	0.3	0.9	0.0	0.3	0.6	-0.3	0.7	1.4	0.6	1.0	-0.4	0.1	0.7	-0.2	0.6	0.7	0.7	0.8
Diabetes diagnosed by doctor	0.4	0.6	3.0	0.7	-0.2	-0.2	-0.7	-0.4	1.7	-0.3	-0.3	0.4	-0.2	0.1	-1.6	-0.3	0.6	1.5	0.6	0.9	-0.1	0.6
Friendships satisfaction	0.4	0.5	1.2	-0.7	0.3	1.1	0.8	1.0	0.9	0.6	0.5	0.5	0.7	0.2	0.9	0.6	0.6	0.5	-0.2	0.6	-0.1	1.0
Qualifications: nursing, teaching	0.4	0.6	2.2	1.2	0.9	0.4	0.6	0.5	0.3	0.8	0.4	0.6	0.5	1.0	0.1	0.5	1.5	0.5	0.8	0.1	1.3	-0.4
Medication: Aspirin	0.4	0.5	2.6	0.0	0.6	0.7	-0.8	0.4	0.1	-0.4	-0.2	-0.1	0.1	0.3	-1.4	0.5	1.6	0.0	0.6	0.1	0.5	-1.3
Average weekly champagne plus white wine intake	0.4	0.5	2.2	0.1	-0.5	-0.4	-1.5	-1.0	0.8	0.3	0.6	0.2	-1.1	0.5	-1.4	0.0	-0.1	-0.8	0.1	-0.9	0.1	0.4
Guilty feelings	0.4	0.5	2.5	0.7	-0.1	0.0	0.1	0.7	0.8	0.7	0.8	1.0	-0.2	0.2	0.1	0.5	0.1	0.1	1.4	1.3	0.2	1.6
Pain type(s) experienced in last month: Hip pain	0.4	0.4	1.7	-0.0	0.6	0.9	1.3	0.5	0.1	0.7	0.7	0.7	0.9	0.7	0.2	0.6	0.6	0.8	0.8	0.4	0.7	0.0
Medication: Atorvastatin	0.4	0.5	2.3	-0.7	-0.6	-0.6	-0.5	-0.9	0.0	-1.5	-0.5	-0.5	-0.8	-0.7	-0.7	-0.2	-0.6	-0.6	0.2	-1.1	-0.7	0.4
Leg fat percentage (left)	0.4	1.3	5.3	2.3	1.0	0.9	1.1	1.6	2.2	-0.6	0.5	0.8	0.5	0.8	0.2	1.0	0.5	0.7	1.4	1.5	1.0	0.9
Commuting to job workplace: Cycle	0.4	0.5	1.6	-0.9	0.7	0.2	1.2	-0.6	0.4	1.3	1.1	0.5	1.0	0.6	1.0	-0.1	-0.0	0.0	-0.0	-1.1	0.6	-0.2
Basal cell carcinoma (self-reported)	0.4	0.5	2.3	-0.6	0.8	0.6	-0.1	0.9	0.7	0.3	0.3	0.6	0.1	0.3	1.1	0.6	0.7	1.0	0.3	0.7	0.5	1.5
Alcohol drinker status: Previous	0.4	0.4	2.6	-0.3	0.3	0.9	0.2	0.5	0.7	-1.6	0.6	-0.0	0.3	0.5	0.3	-0.7	-0.2	1.3	-0.6	-0.5	0.1	-0.5
Depressed Affect (Nagel 2018)	0.3	0.7	3.1	-0.1	0.3	0.7	-0.8	0.6	0.3	-1.7	0.4	1.4	-0.4	1.2	-1.0	0.4	0.9	-0.3	0.6	0.5	0.8	1.3
Depression (Nagel 2018)	0.3	0.5	1.5	0.0	0.0	0.2	-1.1	1.0	0.3	0.6	-0.2	0.9	-0.6	0.4	-0.8	0.8	0.7	-1.2	1.0	0.6	0.2	0.4
Schizophrenia (2018)	0.3	0.6	2.4	0.2	0.0	0.8	1.2	-0.1	0.6	1.1	1.2	1.5	1.3	0.6	0.5	0.6	0.5	0.2	0.4	0.4	0.1	1.0
Alzheimer’s Disease (including proxy)	0.3	0.5	2.0	-0.1	-0.2	0.5	-0.6	-0.3	1.4	-0.6	1.2	0.7	-0.0	0.8	-0.4	0.6	-0.2	-0.7	0.4	-1.2	0.2	1.1
HDL Cholesterol	0.3	0.5	2.3	0.7	0.3	0.6	1.2	1.1	-0.3	0.2	-0.0	0.4	1.1	0.0	1.5	0.2	0.2	0.7	-0.4	0.4	0.1	0.8
Cardiovascular Disease	0.3	1.0	3.8	-1.7	-0.4	-0.8	-1.9	-1.1	1.4	-0.1	0.2	-0.3	-1.8	0.1	-1.6	0.3	0.0	-1.1	0.6	-1.0	0.1	0.9
Average weekly spirits intake	0.3	0.4	1.6	0.1	0.1	-0.8	-0.1	-0.2	1.3	-0.1	0.1	-0.3	-1.1	0.3	0.2	0.3	-1.0	-1.2	0.1	-0.8	0.3	0.6
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.3	0.3	0.3	-0.6	-0.6	-0.6	-0.0	-0.7	-0.5	-0.1	-0.7	0.4	-0.7	-1.1	-1.1	-0.6	0.2	-0.6	0.5	-0.7
Vitamin and mineral supplements	0.3	0.5	3.5	-0.6	-0.5	0.2	-1.2	0.1	-0.4	-0.2	-0.3	-0.2	-0.3	-0.8	-0.4	0.4	0.4	1.9	0.4	0.9	-0.7	0.6
Supplements: Zinc	0.3	0.3	1.4	-0.6	0.2	-0.1	0.2	-0.5	0.7	-1.2	0.3	0.1	-0.3	0.5	-0.0	-0.0	-0.6	-0.9	-0.1	-1.1	0.5	-0.2
Medication: Metformin	0.3	0.4	2.2	0.3	0.0	-0.7	-0.4	-0.8	1.1	0.1	-0.8	-0.5	-0.7	-0.1	-1.5	-1.1	-0.4	-0.1	-0.7	-0.2	0.0	0.4
Diabetes (father)	0.3	0.4	1.8	0.7	0.7	0.2	1.4	0.1	1.1	0.8	0.5	0.3	0.8	0.6	-0.2	0.0	0.6	0.4	0.1	0.5	0.7	0.4
Maternal smoking around birth	0.3	0.5	2.2	-0.5	0.6	-0.1	-1.5	0.7	0.7	-0.0	-0.2	0.2	-1.2	0.4	-0.9	0.1	-0.5	-1.1	0.4	-0.0	0.5	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.4	-1.1	-0.8	-0.3	-1.2	-0.0	-0.3	-0.1	-0.2	0.0	-0.8	-0.7	-0.8	0.2	-0.3	-1.1	-0.1	-0.2	-1.0	-0.5
Taking other prescription medications	0.3	0.5	4.1	-0.1	0.9	0.5	0.3	-0.0	1.1	0.0	0.7	0.6	0.2	0.7	-0.4	0.3	0.5	-0.3	0.7	-0.3	0.8	-2.0
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.3	-1.2	0.6	0.1	0.9	-0.5	0.6	0.6	0.7	0.8	0.2	0.4	0.5	0.4	-0.3	-0.7	0.1	-0.5	0.5	-0.6
Body mass index (BMI)	0.3	1.1	2.9	1.7	0.9	0.8	1.0	1.7	1.7	-0.7	-0.0	0.4	0.2	0.4	0.8	1.2	0.5	0.2	1.7	1.5	0.8	-0.5
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	1.7	0.6	-0.2	0.3	0.1	1.0	-0.0	0.5	0.3	0.6	0.2	0.1	0.1	0.7	0.9	0.5	0.6	0.5	0.0	1.3
Heart attack	0.3	0.4	1.0	0.6	0.4	1.0	0.4	0.4	0.4	-0.2	0.6	0.8	0.8	0.3	0.5	0.7	0.5	0.7	0.6	0.5	0.2	-0.9
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	2.1	0.5	0.7	0.1	0.6	-0.1	-0.5	0.5	0.1	0.2	0.8	0.3	0.9	0.0	0.3	1.4	0.5	0.2	0.6	-1.1
Time employed in main current job	0.3	0.4	1.4	0.3	0.8	0.3	1.2	0.9	0.4	-0.5	-0.1	-0.0	0.5	0.1	0.8	0.8	0.5	0.6	0.3	0.8	0.6	0.7
Happiness	0.3	0.4	2.2	-0.6	-0.6	-0.4	0.5	0.4	-0.5	-0.6	-0.5	-0.7	-0.1	-0.8	0.4	-0.3	-0.6	-0.2	-1.5	0.0	-0.8	0.1
Mouth/teeth dental problems: Dentures	0.3	0.5	2.8	1.7	-0.3	1.1	0.1	0.1	0.1	-1.3	0.1	0.7	1.1	0.2	-0.2	-0.1	0.2	1.5	0.6	0.4	-0.1	0.3
Asthma	0.3	0.6	1.6	-0.7	-0.6	-1.2	-0.8	-0.8	0.3	-0.3	-1.1	-0.9	-0.9	-0.9	-0.5	-0.3	-1.2	-0.1	-0.3	-0.5	-0.7	0.6
Illnesses of mother	0.3	0.4	1.9	0.1	0.4	0.4	1.0	1.0	-0.3	1.4	-0.2	-0.4	0.7	0.0	1.1	-0.1	0.0	-0.5	-0.6	0.3	0.1	-0.4
Breastfed as a baby	0.3	0.4	1.1	-0.9	-0.4	-0.9	-1.1	-0.6	0.3	-0.5	-0.3	-0.4	-1.0	-0.4	-0.5	-0.6	-0.8	-0.6	0.2	-0.7	-0.3	-0.1
Peak expiratory flow (PEF)	0.3	0.6	2.9	0.6	-0.3	-1.0	-0.8	-0.2	-1.7	0.3	-1.5	-0.3	-0.5	-0.7	-0.0	-0.8	-0.2	-0.6	-0.5	0.3	-0.5	-1.2
Ever highly irritable/argumentative for 2 days	0.3	0.3	3.5	0.3	-0.2	-0.2	-0.2	0.6	-0.2	-0.1	-0.2	0.4	-0.3	-0.3	0.3	0.9	0.2	0.1	0.8	1.9	-0.2	0.1
Gout (self-reported)	0.3	0.5	1.8	0.6	0.7	0.5	1.0	0.6	0.2	0.2	0.6	0.8	1.0	0.5	0.6	0.7	0.4	0.5	0.4	1.3	0.6	-0.6
Number of full brothers	0.3	0.4	1.0	-0.5	1.0	-0.3	0.6	0.2	-0.5	-0.6	-0.1	-0.9	0.3	-0.2	1.0	0.2	-0.3	-0.9	0.5	-0.2	0.2	-0.9
Number of children fathered	0.3	0.4	1.9	-0.1	-0.0	0.0	1.0	0.1	-1.4	0.4	-0.2	-0.5	0.6	-0.4	-0.0	-0.9	-0.8	0.0	-0.9	-0.6	-0.3	-0.9
Emphysema/chronic bronchitis	0.3	0.3	2.0	-0.3	-0.1	-0.1	-0.2	-0.3	-0.1	-0.6	0.1	-0.2	-0.3	0.0	-0.3	-0.1	-0.5	-1.4	-0.3	-0.9	-0.0	-1.4
Neck or shoulder pain in last month	0.3	0.5	2.0	0.2	0.0	-0.9	0.7	-1.1	0.7	-1.3	0.2	-0.1	-0.4	-0.1	-0.2	-0.6	-1.4	0.3	0.6	-0.8	0.2	0.3
Medication: Omeprazole	0.3	0.4	2.0	-0.0	1.2	0.2	1.4	-0.1	0.0	-0.8	0.4	-0.2	0.2	0.9	-0.0	-0.1	0.4	-0.3	-0.3	-1.1	1.0	-0.5
Leg fat mass (right)	0.3	1.1	7.1	2.7	0.6	0.2	0.6	1.1	2.0	-0.5	-0.2	0.6	0.2	0.4	0.2	0.9	0.3	-0.2	1.8	1.5	0.7	0.4
Family relationship satisfaction	0.3	0.4	2.0	-1.4	0.1	0.0	0.4	0.9	0.3	0.1	-0.2	-0.5	-0.5	-0.2	0.9	0.6	0.1	-1.0	-0.6	-0.1	-0.2	0.7
Leg pain on walking	0.3	0.3	2.5	-0.4	0.0	-0.8	-0.6	0.1	0.0	1.6	0.0	-0.3	-0.9	0.1	-0.2	-0.6	-0.3	-0.4	0.1	-0.8	0.2	0.2
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.3	0.8	-0.3	0.9	-0.6	0.4	0.8	0.7	0.7	0.8	0.6	0.5	0.0	0.5	0.6	1.1	0.2	0.1	-0.2	-0.0
Illnesses of siblings: Diabetes	0.3	0.4	3.2	0.6	0.1	0.7	-0.5	0.8	0.3	0.2	-0.8	-0.3	0.3	-0.2	-0.6	-0.6	0.7	-0.4	-0.2	0.3	-0.0	-1.8
Mood swings	0.3	0.6	3.3	-1.3	-0.2	-0.3	-0.9	-0.8	-0.1	-1.8	0.3	0.0	-1.2	0.2	-1.1	0.2	-0.1	-0.6	0.1	-0.8	0.0	0.9
Asthma (self-reported)	0.3	0.6	1.8	-0.7	-0.6	-1.3	-0.8	-0.9	0.2	-0.7	-1.1	-1.0	-1.0	-0.9	-0.7	-0.4	-1.3	-0.1	-0.3	-0.6	-0.6	0.2
Medication: Gliclazide	0.3	0.4	1.2	1.0	-0.4	-0.6	-0.6	-0.4	0.9	0.6	-0.4	0.6	-0.3	-0.1	-1.1	-0.8	-0.5	0.4	-0.3	0.9	-0.3	-0.0
Illnesses of father: None of the above (group 1)	0.3	0.3	0.9	0.3	-1.0	-0.7	0.2	-0.4	-0.1	0.4	0.5	0.5	0.0	-0.4	0.9	0.8	-0.6	-0.1	0.7	0.0	-0.5	0.9
Miserableness	0.3	0.6	3.7	-0.7	-0.1	0.5	-0.7	0.9	-0.7	-1.9	-0.5	0.4	-0.3	0.1	-0.5	0.2	0.6	0.7	0.0	0.6	-0.0	1.8
Mother’s age at death	0.3	0.4	1.2	-1.1	-0.9	-0.3	-1.0	-0.6	-0.5	0.1	-0.2	-0.1	-0.3	-1.0	-0.1	-0.4	-0.5	0.2	0.0	-0.8	-0.9	-0.4
Tinnitus: Yes, now most or all of the time	0.3	0.3	2.3	0.2	-0.6	0.3	0.2	-0.2	0.2	0.2	1.5	1.1	0.3	0.4	-0.2	0.6	-0.6	0.6	0.2	0.0	-0.3	-0.6
Illnesses of father: High blood pressure	0.3	0.4	2.9	-0.9	0.7	0.0	-0.4	-0.2	-0.2	-0.8	-0.3	-0.4	-0.7	0.3	-0.4	-0.1	0.8	-0.7	0.1	0.1	0.6	-1.7
Risk taking	0.3	0.4	1.7	-0.1	-0.6	-0.9	0.5	-0.9	-1.3	0.2	-0.6	-0.8	-0.0	-0.9	-0.0	-0.7	-0.5	0.4	-0.6	0.2	-0.7	-0.7
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.5	0.8	-0.8	-0.1	-0.4	-0.1	-0.1	-0.5	0.1	0.4	-0.3	0.2	-0.8	-1.2	-0.5	-0.5	-0.8	-0.6	-0.3	-0.8
Myopia	0.3	0.4	4.3	0.7	0.3	-0.2	-0.1	-0.1	0.5	2.1	0.1	0.5	0.2	0.4	-0.8	0.2	0.5	0.7	0.5	0.9	0.4	-0.1
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.1	0.7	0.4	1.0	0.5	0.4	0.4	-0.3	0.7	0.9	0.9	0.4	0.5	0.8	0.6	0.8	0.7	0.6	0.3	-1.0
Bipolar Disorder or Schizophrenia	0.2	0.6	1.5	-0.8	-1.2	-0.6	-0.1	-1.0	-1.1	-0.5	-0.2	0.0	0.0	-1.0	-0.3	-0.8	-0.9	-0.9	-0.9	-0.9	-1.2	-0.2
Neuroticism (Nagel 2018)	0.2	0.5	1.7	-0.2	0.4	0.3	-0.6	0.5	0.5	-1.3	0.4	1.1	-0.7	0.9	-0.4	0.5	0.2	-0.7	1.0	0.6	0.8	1.0
Worry (Nagel 2018)	0.2	0.3	1.3	-0.5	-0.7	-0.6	-0.9	-0.6	0.2	-0.7	0.0	0.5	-1.1	-0.0	-0.6	0.1	-0.3	-0.9	0.8	-0.2	-0.2	0.3
Mean Putamen Volume	0.2	0.2	1.4	-0.4	0.1	-0.2	-0.2	-0.2	0.3	0.0	0.5	0.1	-0.5	0.1	0.2	0.7	-0.0	-1.2	1.0	-0.3	0.2	0.5
Triglycerides	0.2	0.3	1.2	-1.1	0.3	0.2	0.6	-0.2	0.7	0.2	0.6	0.1	0.0	0.1	0.3	1.1	0.7	-0.1	1.0	-0.1	0.1	-0.3
Ulcerative Colitis	0.2	0.3	1.8	-0.3	0.2	0.1	0.4	0.2	-0.3	0.9	-0.0	-0.1	-0.0	0.2	0.3	-0.7	0.2	1.3	-0.6	0.7	0.0	0.6
Blood Red Count	0.2	1.7	7.8	-1.8	-0.8	-1.4	-0.7	0.0	-0.7	-0.4	-1.2	-1.5	-1.0	-1.9	-0.1	-0.0	-0.2	2.6	-0.3	1.1	-1.4	2.8
Neuroticism	0.2	0.4	1.4	-0.6	-0.3	-0.2	-1.1	-0.1	0.3	-1.0	0.3	0.7	-1.0	0.4	-0.7	0.1	-0.0	-0.7	0.7	0.2	0.1	1.2
Chronotype (morning person)	0.2	0.4	1.7	-0.4	-0.4	-0.1	-0.1	-1.2	0.9	0.4	0.6	-0.3	0.1	0.2	-0.3	-0.4	-1.2	-0.3	0.2	-1.3	-0.1	0.3
Relative age of first facial hair	0.2	0.3	1.2	-0.4	0.6	0.4	-0.3	1.1	0.9	1.0	-0.3	-0.1	0.3	0.5	-0.2	-0.8	0.2	0.6	-0.2	-0.8	0.4	-0.3
Current tobacco smoking	0.2	0.3	0.9	-0.6	-0.4	-0.2	-0.3	-0.0	-0.8	0.4	-0.6	-0.3	-0.2	-0.7	0.1	-0.1	-0.9	-0.5	-0.3	-0.2	-0.6	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.2	-1.1	-1.0	-0.2	-0.9	0.1	-0.4	0.9	0.4	-0.1	-0.8	-0.4	-1.1	0.1	-0.2	0.0	0.1	-0.5	-0.7	0.9
High blood pressure	0.2	0.6	2.2	-0.9	0.5	0.3	0.5	-0.2	1.4	-0.2	1.1	0.5	0.1	0.7	-0.1	1.5	1.2	0.2	1.2	-0.1	0.7	0.4
Stomach or abdominal pain in last month	0.2	0.2	1.1	0.0	0.5	0.0	0.6	-0.0	0.6	-0.6	0.5	0.0	-0.0	0.2	-0.5	0.2	0.0	0.8	1.0	0.1	0.5	0.2
Medication: Atenolol	0.2	0.3	1.8	-0.2	0.0	-0.3	-0.6	-0.0	-0.1	-0.4	-0.6	-0.6	-0.6	-0.1	-0.7	-0.7	-0.3	-0.3	-1.0	-0.4	0.0	-1.3
High blood pressure (mother)	0.2	0.3	1.5	0.1	-0.4	0.5	-0.3	-0.4	0.5	-1.0	0.5	1.2	0.4	0.4	-0.3	0.3	0.5	0.8	0.2	0.1	-0.0	1.2
Trunk fat mass	0.2	0.9	8.1	2.8	0.3	-0.4	0.4	0.6	1.7	-0.8	-0.5	0.3	-0.2	0.2	-0.5	0.5	-0.1	-0.3	1.4	1.1	0.5	0.7
Number of incorrect matches in round	0.2	0.3	1.2	-0.3	0.2	0.3	0.1	0.0	0.6	-0.6	1.1	0.9	0.2	0.7	1.1	0.4	0.1	0.3	0.8	-0.5	0.5	0.5
Hearing difficulty/problems with background noise	0.2	0.3	1.0	-0.4	-0.6	-0.8	-0.1	-0.6	-0.7	-0.6	-0.3	-0.4	-0.4	-0.6	0.1	0.1	-0.0	0.2	0.2	1.0	-0.7	-0.9
Medication: Ramipril	0.2	0.2	1.1	0.3	-0.5	-0.1	-0.7	-0.6	0.2	-0.7	0.2	0.4	-0.2	-0.0	-1.1	0.2	-0.5	-0.2	-0.0	-0.1	-0.3	0.3
Hip circumference	0.2	0.8	4.9	2.2	-0.6	-1.1	-0.2	0.2	0.6	-0.6	-1.4	-0.3	-0.5	-0.8	-0.3	-0.2	-0.6	-0.9	1.1	1.1	-0.5	-0.3
Alcohol intake versus 10 years previously	0.2	0.2	0.9	0.2	-0.1	0.3	1.0	0.4	0.5	0.5	0.4	-0.1	0.7	0.2	0.5	0.4	0.3	0.9	-0.1	0.1	-0.0	0.9
Father’s age at death	0.2	0.2	0.8	0.1	-0.2	-0.8	-0.4	-0.3	-0.2	0.9	-0.2	-0.4	-0.9	-0.4	-0.1	-0.5	-0.6	-0.6	0.1	0.4	-0.2	0.4
Pulse rate	0.2	0.4	2.7	-0.1	0.4	-0.5	0.8	-0.1	0.6	1.1	1.7	0.3	-0.2	0.6	-0.2	0.9	0.3	-0.1	1.0	0.1	0.5	0.2
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.3	-0.8	-0.2	-0.3	-0.3	-0.3	-0.6	-0.2	0.5	-0.3	-0.5	-0.2	-0.7	-0.1	-0.5	-0.5	-0.8	-1.1	-0.2	0.3
Arm fat mass (right)	0.2	0.9	5.2	2.3	0.7	0.2	0.8	1.1	1.8	-0.6	-0.3	0.4	0.2	0.3	0.5	1.0	0.2	-0.1	1.8	1.2	0.7	-0.1
Medication: Amlodipine	0.2	0.3	0.9	-0.2	0.1	0.0	-0.1	-0.6	0.5	0.9	0.7	0.4	0.3	0.3	-0.6	0.4	0.4	0.7	0.8	0.4	0.1	-0.9
High blood pressure (siblings)	0.2	0.2	0.6	-0.4	-0.4	0.0	-0.6	-0.8	0.3	-0.3	-0.2	-0.0	-0.4	-0.1	-0.8	-0.8	-0.5	-0.7	-0.2	-0.6	-0.3	-0.3
Comparative body size at age 10	0.2	0.4	1.0	-0.7	-1.0	0.3	-0.7	0.7	-1.0	-1.0	-1.0	-0.1	-0.5	-1.0	0.1	0.2	0.1	-0.7	0.1	-0.0	-1.0	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.9	-0.1	0.4	0.4	0.1	0.7	0.9	1.0	0.5	0.6	-0.0	0.5	0.2	0.4	0.6	-0.9	0.7	0.6	0.5	0.1
Age at first live birth	0.2	0.4	2.4	-0.6	0.7	-0.3	0.9	0.4	-0.0	1.5	-0.3	-0.6	0.2	0.1	0.7	0.3	0.4	0.4	-0.6	0.5	0.3	0.7
Shortness of breath walking on level ground	0.2	0.3	1.0	-1.0	0.4	-0.4	-0.2	0.0	0.8	0.3	0.6	0.3	-0.6	0.4	-0.2	0.9	0.1	-0.3	0.8	-0.6	0.4	0.7
Qualifications: College or University degree	0.2	0.6	2.0	0.5	-1.0	-0.7	-0.8	-1.4	-0.8	0.4	0.1	-0.8	-0.5	-0.5	-1.4	-0.2	-0.2	-0.4	-0.6	-0.8	-0.7	-1.1
Medication: Ibuprofen	0.2	0.2	1.1	-0.8	-0.0	-0.4	-0.2	-0.5	-0.5	-0.3	0.4	-0.4	-0.3	-0.1	-0.6	0.1	-0.4	-0.6	-0.9	-1.1	-0.1	-0.3
Medication: Seretide 50 evohaler	0.2	0.3	1.4	-0.1	0.9	-0.5	1.2	-0.3	-0.0	0.1	-0.3	-0.5	0.1	0.1	-0.0	0.4	-0.3	-0.9	-0.3	-0.2	0.7	-0.8
Whole body fat mass	0.2	0.9	7.4	2.7	0.4	-0.3	0.7	0.8	1.7	-0.7	-0.4	0.4	-0.0	0.3	-0.2	0.6	0.0	-0.1	1.5	1.3	0.6	0.3
Overall health rating	0.2	0.5	2.1	-0.3	1.5	0.1	0.9	-0.1	1.1	-0.4	0.4	0.3	0.1	0.9	0.0	0.7	0.6	0.6	0.2	0.3	1.3	-0.7
Chest pain or discomfort	0.2	0.3	1.0	-1.0	-0.6	-0.0	-0.5	-0.2	-0.2	-0.5	-0.8	-0.1	-0.2	-0.6	-0.3	-0.7	-0.1	-0.0	-0.4	-0.4	-0.6	0.8
Had major operations	0.2	0.2	1.0	0.4	-1.0	0.0	0.4	-0.4	0.0	0.0	0.9	0.4	-0.2	-0.2	-1.0	-0.1	-0.2	0.0	0.3	0.3	-0.5	-0.8
Hypertension (Self-reported)	0.2	0.5	2.4	-0.5	0.2	0.4	0.3	-0.2	1.5	-0.1	0.8	0.4	0.0	0.6	-0.4	1.2	1.2	0.4	1.0	0.0	0.6	0.4
Handedness (chirality/laterality): Left-handed	0.2	0.3	1.0	-0.4	-0.2	0.4	0.0	-0.2	-1.0	0.8	0.4	-0.5	0.6	0.0	-0.2	-0.0	0.8	0.4	-0.9	-0.1	-0.5	0.0
Ever had bowel cancer screening	0.2	0.2	1.7	0.7	0.4	0.0	0.3	-0.0	-0.2	-0.5	0.0	1.0	0.1	0.4	-0.3	-0.4	0.3	0.5	0.1	0.3	0.4	-1.3
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.9	-0.2	0.7	0.7	0.3	0.2	0.1	0.7	0.3	-0.1	0.5	0.5	0.7	0.6	0.7	0.6	-0.4	-0.1	0.6	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	0.9	0.4	0.5	-0.1	0.9	0.3	1.0	-0.4	0.6	0.6	0.1	0.5	0.3	0.7	0.2	-0.5	0.7	0.0	0.5	-0.0
Back pain experienced in last month	0.2	0.2	1.7	0.3	-0.2	0.3	1.3	0.4	-0.4	-0.1	0.5	0.3	0.7	0.1	0.7	0.6	0.3	0.3	0.3	0.6	-0.1	-0.0
Arm fat mass (left)	0.2	0.9	5.2	2.3	0.5	0.1	0.7	1.1	1.8	-0.5	-0.3	0.4	0.0	0.3	0.3	0.9	0.2	-0.2	1.8	1.1	0.6	-0.1
Ever taken oral contraceptive pill	0.2	0.2	0.8	0.6	-0.1	-0.2	-0.5	0.5	-0.9	0.1	-0.6	-0.5	-0.4	-0.1	-0.3	-0.5	-0.5	-0.6	0.1	-0.2	-0.1	-0.6
Financial situation satisfaction	0.2	0.2	1.8	-1.3	0.1	-0.4	-0.3	0.0	0.2	0.3	0.1	-0.5	-0.7	-0.0	0.1	0.8	0.5	-0.8	0.0	-0.3	-0.0	-0.0
Medication: Blood pressure	0.2	0.4	1.3	-0.1	0.1	-0.4	0.8	-0.8	0.9	0.1	0.7	0.5	-0.3	1.0	-0.8	0.2	0.1	-0.9	0.4	-0.8	0.9	-1.1
High cholesterol (Self-reported)	0.2	0.3	1.3	-0.5	-0.2	-0.1	-0.9	0.1	0.6	-0.8	-0.1	-0.4	-0.9	-0.2	-1.2	-0.2	0.1	-0.4	0.6	-0.3	-0.1	0.1
Average weekly beer plus cider intake	0.2	0.3	2.7	0.3	0.2	-0.3	-0.2	-0.7	-0.3	-1.6	0.0	-0.1	-0.2	0.0	-0.1	0.2	-0.0	0.4	0.3	-0.1	0.2	-1.2
Irritability	0.2	0.3	0.8	-0.1	0.4	0.3	-0.7	0.3	-0.2	-0.9	0.2	0.9	-0.3	0.7	-0.1	0.6	0.4	-0.1	0.7	0.7	0.6	0.7
Diastolic blood pressure, automated reading	0.2	0.5	2.5	-0.1	-0.3	-0.6	0.2	-0.9	-0.8	-1.3	-0.2	-1.6	-0.2	-0.8	-0.6	-0.1	-0.4	0.5	-0.5	-0.5	-0.4	-1.2
Ever depressed for a whole week	0.2	0.3	0.9	-0.1	-0.1	-0.5	-0.7	-0.0	-0.7	-0.8	-0.9	-0.8	-0.6	-0.4	-0.7	-0.2	0.6	-0.7	-0.2	0.0	-0.0	-0.2
Vascular/heart problems diagnosed by doctor	0.2	0.6	2.1	1.0	-0.2	-0.1	0.0	0.4	-1.3	0.0	-1.1	-0.3	0.3	-0.5	0.6	-1.4	-1.3	0.0	-1.3	0.3	-0.5	-0.2
Pack years of smoking	0.2	0.3	1.9	1.4	0.2	0.2	-0.5	0.2	0.4	-0.7	-0.0	0.3	0.0	0.5	-0.2	0.5	0.3	-0.3	0.7	1.1	0.3	-0.3
Leg fat mass (left)	0.2	0.7	5.4	2.3	0.0	-0.2	0.3	0.6	1.7	-0.6	-0.4	0.3	-0.2	-0.0	-0.4	0.5	-0.2	-0.6	1.3	1.0	0.2	0.2
Schizophrenia vs Biploar Disorder	0.1	0.2	1.2	0.1	0.2	0.4	0.3	-0.2	0.5	1.1	0.3	0.4	0.4	0.3	0.1	0.2	0.2	0.4	0.2	0.3	0.3	-0.1
Major Depression (MDD)	0.1	0.1	0.5	-0.3	0.4	-0.0	0.7	0.3	0.2	0.4	0.1	-0.1	0.1	0.5	0.0	0.1	0.1	-0.5	-0.6	-0.1	0.5	0.0
Schizophrenia (2014)	0.1	0.2	0.6	-0.3	-0.6	-0.1	0.1	-0.4	-0.4	0.6	0.3	0.8	0.3	-0.3	0.1	-0.3	-0.5	-0.7	0.0	-0.2	-0.5	0.1
Blood Eosinophil Count	0.1	0.6	3.3	-0.8	-0.8	-0.6	-1.0	-0.7	0.9	0.8	-0.0	-0.1	-0.5	-0.4	-0.4	-0.2	-0.7	1.0	-0.1	-1.0	-0.7	1.8
BMI	0.1	0.6	2.0	1.1	0.4	0.2	0.2	1.2	1.4	-1.3	-0.4	0.1	-0.4	-0.2	0.4	0.8	-0.1	0.2	1.4	1.3	0.3	0.3
Allergy or Eczema	0.1	0.2	1.0	0.1	0.5	-0.2	0.3	0.1	-0.7	-0.8	0.2	0.0	-0.2	0.2	1.0	-0.1	-0.4	0.0	-0.5	-0.5	0.2	-0.8
Hair Pigment	0.1	2.5	27.2	1.0	-0.0	0.2	0.2	0.1	-1.2	1.9	1.6	1.7	0.7	0.9	1.3	0.8	0.5	-1.2	1.6	1.0	0.6	-5.2
Tanning	0.1	0.7	3.2	-0.5	-0.8	-1.0	-1.3	-0.5	0.0	-0.3	-0.5	-0.1	-1.7	-0.5	-0.9	-0.4	-1.8	-0.9	0.6	-0.4	-0.6	0.8
Angina	0.1	0.1	0.4	-0.4	0.4	0.1	0.4	0.4	-0.1	0.4	0.0	-0.2	-0.1	0.1	-0.4	0.6	0.5	0.5	0.1	0.6	0.1	-0.3
Pack years adult smoking proportion	0.1	0.2	0.6	0.7	-0.2	-0.3	-0.5	-0.0	-0.1	-0.7	-0.4	-0.3	-0.2	-0.1	-0.2	0.3	-0.2	-0.7	0.4	0.8	-0.2	-0.4
Townsend deprivation index at recruitment	0.1	0.2	1.4	-1.2	-0.1	0.1	-0.3	-0.1	-0.1	-0.7	-0.2	-0.2	0.1	-0.4	0.5	0.8	0.1	0.4	0.7	-0.0	-0.4	0.0
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.8	-0.1	-0.2	-0.4	-0.3	0.1	-0.9	-0.4	-0.7	-0.1	-0.5	-0.5	0.6	-0.6	-0.6	-0.4	-0.8	-0.5	-0.5	0.0
Nervous feelings	0.1	0.2	0.7	-0.6	0.1	-0.3	-0.1	-0.4	0.5	-0.0	0.6	0.4	-0.4	0.2	-0.1	0.7	0.0	0.3	0.8	-0.1	0.2	0.9
Fluid intelligence score	0.1	0.3	1.2	0.4	-0.1	0.0	-0.4	0.2	-0.7	-0.2	-1.1	-1.0	-0.3	-0.4	-0.4	-0.5	0.0	0.1	-0.8	-0.2	-0.1	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.7	0.0	-0.4	-0.0	-0.4	0.6	-0.1	0.3	-0.2	0.7	-0.4	-0.2	-0.2	-0.1	-0.0	-0.8	0.4	0.3	-0.2	0.1
Blood clot in the leg (DVT)	0.1	0.2	0.9	-0.5	0.0	-0.6	-0.1	-0.5	-0.0	-0.4	0.1	0.0	-0.5	-0.2	0.0	0.7	0.2	0.1	0.9	0.2	-0.0	-0.7
Angina (self-reported)	0.1	0.1	0.7	-0.8	0.2	-0.1	0.3	0.1	-0.3	0.4	-0.2	-0.5	-0.2	-0.2	-0.4	0.4	0.2	0.4	-0.1	0.3	-0.1	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.2	0.7	0.4	-0.3	0.1	-0.5	0.1	-0.9	-0.7	-0.4	0.3	-0.3	-0.3	-0.7	-0.1	0.0	-0.4	0.2	0.4	-0.1	0.4
Pulse rate, automated reading	0.1	0.2	0.7	0.0	0.0	-0.8	-0.1	-0.4	0.8	0.6	0.7	0.1	-0.5	0.3	-0.6	0.0	-0.3	0.4	0.8	0.1	0.3	0.2
Suffer from ‘nerves’	0.1	0.2	0.8	-0.5	-0.3	0.1	-0.3	0.2	0.6	-0.2	0.2	0.5	-0.4	-0.0	0.3	0.4	-0.3	-0.7	0.8	0.0	-0.0	0.9
Hearing aid user	0.1	0.1	0.8	0.2	-0.2	0.2	0.0	0.1	0.1	0.2	0.9	0.3	0.0	0.4	-0.3	0.2	-0.5	0.3	0.2	-0.2	-0.1	-0.8
Commuting to job workplace: Public transport	0.1	0.2	1.1	0.5	0.3	0.6	0.2	0.5	1.0	-0.1	0.5	0.2	-0.0	0.4	-0.1	0.4	0.2	-0.3	0.2	0.3	0.4	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.9	-0.5	0.2	-0.4	0.0	-0.5	-0.1	-0.3	0.2	0.1	-0.3	-0.1	0.3	0.8	0.3	0.5	0.9	0.3	0.1	-0.5

Hub : Genes

BEND3P3

Models

Trait associations