[Hub]/) : Traits : Sitting height : ← →

chr12:93,110,493-94,675,142

Best TWAS P=9.21e-48 · Best GWAS P=2.36e-107 conditioned to 9.38e-36

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Breast Mammary Tissue (Male) MRPL42 0.21 -0.01 lasso 2 -0.01 6.0e-01 13.4 -13.2 1.1e-39 -0.47 0.05 0.05 TRUE
2 GTEx Muscle Skeletal MRPL42 0.07 0.02 lasso 3 0.04 1.5e-04 -7.5 -7.7 1.5e-14 -0.16 0.70 0.01 FALSE
3 GTEx Skin Sun Exposed Lower leg UBE2N 0.09 0.07 lasso 2 0.06 1.6e-05 7.8 7.0 3.6e-12 0.17 0.91 0.00 TRUE
4 GTEx Small Intestine Terminal Ileum MRPL42 0.49 -0.01 enet 25 0.00 3.8e-01 -2.9 -5.6 2.1e-08 -0.11 0.06 0.06 TRUE
5 GTEx Testis MRPL42 0.35 0.17 lasso 3 0.24 3.3e-11 -4.3 -6.4 1.3e-10 -0.14 1.00 0.00 FALSE
6 NTR Blood SOCS2 0.04 0.02 bslmm 454 0.02 6.5e-08 12.9 8.7 4.0e-18 -0.22 1.00 0.00 FALSE
7 YFS Blood SOCS2 0.06 0.04 bslmm 444 0.04 1.7e-12 12.9 14.5 9.2e-48 0.07 1.00 0.00 TRUE
8 YFS Blood UBE2N 0.02 0.00 bslmm 424 0.01 3.6e-03 19.0 8.9 4.0e-19 0.38 0.06 0.31 TRUE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MRPL42 0.05 0.02 blup 49 0.03 5.1e-04 6.0 6.5 7.8e-11 0.15 0.06 0.19 FALSE
10 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma MRPL42 0.11 0.06 lasso 2 0.09 7.1e-07 -4.9 5.5 4.6e-08 0.15 0.02 0.97 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma MRPL42 0.07 0.03 blup 49 0.03 1.4e-04 -4.4 7.6 3.5e-14 0.21 0.26 0.65 FALSE
12 The Cancer Genome Atlas Stomach Adenocarcinoma MRPL42 0.12 0.01 blup 49 0.04 4.0e-04 -4.4 5.9 2.9e-09 0.18 0.02 0.13 FALSE