Best TWAS P=4.17e-12 · Best GWAS P=1.63e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | ADAM15 | 0.14 | 0.09 | lasso | 4 | 0.08 | 6.1e-07 | 6.7 | -6.9 | 4.2e-12 | -0.96 | 0 | 1 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | ZBTB7B | 0.05 | 0.06 | lasso | 2 | 0.05 | 1.8e-06 | 6.7 | -6.7 | 1.7e-11 | -1.00 | 0 | 1 | FALSE |