Best TWAS P=3.23e-12 · Best GWAS P=9.62e-14 conditioned to 3.34e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | ARHGEF40 | 0.34 | 0.32 | enet | 17 | 0.31 | 1.5e-17 | -5.9 | -6.1 | 1.0e-09 | 0.00 | 0.64 | 0.36 | TRUE |
2 | GTEx | Cells Transformed fibroblasts | TOX4 | 0.19 | 0.06 | lasso | 7 | 0.05 | 6.6e-05 | -5.3 | -5.4 | 6.2e-08 | -0.31 | 0.71 | 0.06 | FALSE |
3 | GTEx | Testis | TOX4 | 0.31 | 0.00 | enet | 24 | 0.04 | 6.8e-03 | -5.2 | -7.0 | 3.2e-12 | -0.58 | 0.04 | 0.58 | TRUE |