TWAS hub - TOX4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.2290	0.0640	5.1e-04	0.019	NA	-0.005	NA	0.011	3.5e-02	NA	7.7e-01	NA	8.5e-02
2	GTEx	Cells Transformed fibroblasts	0.1890	0.0530	2.8e-04	0.056	NA	0.038	NA	0.054	5.1e-05	NA	7.9e-04	NA	6.6e-05
3	GTEx	Esophagus Muscularis	0.2200	0.0550	6.3e-05	0.024	NA	0.047	NA	0.042	1.2e-02	NA	8.0e-04	NA	1.4e-03
4	GTEx	Lung	0.1791	0.0499	1.0e-04	0.072	NA	0.035	NA	0.053	3.5e-06	NA	1.1e-03	NA	6.9e-05
5	GTEx	Nerve Tibial	0.1369	0.0479	3.0e-03	0.027	NA	0.012	NA	0.049	4.9e-03	NA	4.3e-02	NA	2.2e-04
6	GTEx	Testis	0.3140	0.0990	6.3e-03	-0.001	NA	0.040	NA	0.029	3.6e-01	NA	6.8e-03	NA	1.9e-02
7	METSIM	Adipose	0.0399	0.0155	1.8e-03	0.025	0.019	0.030	0.026	0.033	1.0e-04	5.5e-04	1.9e-05	7.8e-05	8.8e-06
8	YFS	Blood	0.1158	0.0179	0.0e+00	0.093	0.094	0.123	0.116	0.122	9.1e-29	4.2e-29	4.9e-38	8.3e-36	7.0e-38
9	TCGA	Breast Invasive Carcinoma	0.0202	0.0099	4.8e-04	0.022	0.014	0.013	NA	0.015	1.6e-05	5.4e-04	6.9e-04	NA	3.8e-04
10	TCGA	Colon Adenocarcinoma	0.0720	0.0370	3.1e-03	0.034	0.031	0.045	NA	0.014	4.5e-03	6.2e-03	1.3e-03	NA	4.8e-02
11	TCGA	Kidney Renal Clear Cell Carcinoma	0.0548	0.0228	6.8e-05	0.033	0.038	0.027	NA	0.029	1.2e-04	3.9e-05	4.4e-04	NA	2.6e-04
12	TCGA	Brain Lower Grade Glioma	0.1540	0.0459	1.9e-12	0.043	0.107	0.096	NA	0.092	1.1e-05	3.7e-12	4.9e-11	NA	1.2e-10
13	TCGA	Prostate Adenocarcinoma	0.0785	0.0287	2.5e-08	0.108	0.073	0.087	NA	0.105	2.1e-11	4.0e-08	2.0e-09	NA	4.9e-11
14	TCGA	Rectum Adenocarcinoma	0.2180	0.1070	7.9e-03	0.008	0.045	0.026	NA	0.067	2.0e-01	3.2e-02	8.1e-02	NA	1.1e-02
15	TCGA	Thyroid Carcinoma	0.0970	0.0360	5.4e-09	0.078	0.062	0.085	NA	0.038	4.6e-08	1.2e-06	1.1e-08	NA	1.4e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Commuting to job workplace: Cycle	6.7	8.1	14.6	-1.2	-0.5	-2.8	-3.3	-1.4	1.0	-3.3	2.9	-3.4	-2.8	-3.8	-3.7	-3.6	-2.4	-3.5
Bilateral oophorectomy (both ovaries removed)	3.9	4.5	12.5	2.4	-1.7	0.9	2.4	-0.1	-1.6	1.9	-0.7	3.5	0.5	3.3	2.8	1.8	0.6	3.3
Osteoporosis (self-reported)	3.8	4.7	9.0	2.5	1.7	2.5	2.3	2.0	1.4	2.1	-2.1	1.1	3.0	2.7	2.1	2.2	2.0	1.8
Alzheimer’s Disease (including proxy)	3.4	4.9	8.7	1.1	1.8	2.7	2.6	2.3	3.0	2.7	-2.2	1.5	1.3	1.9	2.3	2.6	2.0	2.3
HbA1C	3.2	3.5	5.0	-2.1	-1.3	-2.2	-2.0	-1.6	-0.4	-2.2	1.9	-1.8	-2.0	-1.9	-1.8	-2.2	-2.0	-2.1
Medication: Blood pressure	3.0	5.3	12.3	-0.6	-0.7	-1.6	-3.5	-1.7	-0.8	-2.9	2.5	-2.6	-1.8	-2.5	-2.4	-3.0	-2.3	-3.1
Age started oral contraceptive pill	2.8	3.5	10.4	-0.3	1.4	1.2	2.4	0.8	1.2	1.5	-3.2	1.2	2.1	1.4	1.2	2.8	3.0	1.5
Deep venous thrombosis (DVT) (self-reported)	2.6	3.4	5.9	0.8	1.1	2.0	2.4	2.1	1.1	2.4	-1.4	1.2	2.4	2.3	2.1	1.8	1.2	2.0
Alzheimer’s Disease (in father)	2.5	2.7	5.0	0.6	0.4	1.5	2.0	1.0	1.2	1.9	-1.5	1.9	1.3	1.8	2.2	1.9	1.6	2.2
Eye problems/disorders: Diabetes related eye disease	2.4	2.6	4.9	-0.7	0.2	-0.4	1.7	0.4	-1.8	1.7	-1.8	2.1	2.2	2.1	1.0	2.1	1.7	2.1
Medication: Ibuprofen	2.4	2.8	9.6	1.0	-1.8	-1.3	-1.7	-1.3	-2.5	-1.0	2.4	-0.8	-1.6	-0.7	-1.2	-1.8	-3.1	-0.8
Alcohol drinker status: Never	2.4	2.9	11.4	-0.7	3.4	1.3	-0.1	2.1	2.6	-0.1	-1.5	-2.7	2.1	-1.0	-1.0	0.2	0.8	-1.3
Heart disease (mother)	2.3	2.8	5.1	-0.5	-1.6	-1.8	-1.9	-2.0	-1.7	-2.3	1.7	-1.1	-0.8	-1.7	-1.8	-1.9	-1.3	-2.0
Ever had prostate specific antigen (PSA) test	2.3	2.7	7.4	-0.1	-2.1	-1.0	-1.5	-2.6	-1.3	-2.1	1.5	-0.1	-1.8	-1.8	-2.7	-1.4	-0.7	-1.1
Blood clot in the leg (DVT)	2.2	2.8	5.0	0.9	0.7	1.8	2.2	1.8	0.8	2.2	-1.1	1.3	2.0	2.2	2.0	1.6	0.9	1.9
Heart attack	2.1	2.7	5.3	-0.6	-0.4	-1.0	-2.3	-0.4	-0.3	-1.4	2.2	-2.0	-1.6	-1.7	-2.0	-2.3	-1.9	-2.2
Alcohol usually taken with meals	2.0	3.2	9.0	-1.7	-0.5	-1.8	-1.8	-1.3	1.0	-2.4	1.1	-1.9	-1.0	-3.0	-2.4	-1.8	-0.3	-2.4
Ever had stillbirth, spontaneous miscarriage or termination	2.0	2.2	8.4	0.9	-1.7	0.0	1.5	-1.3	-1.9	0.6	-1.2	2.9	0.1	1.3	0.4	1.7	1.5	1.9
Number of operations (self-reported)	2.0	2.9	12.3	1.3	-2.9	-0.9	-1.2	-2.2	-3.5	-1.2	2.0	0.9	-2.1	-0.0	-0.8	-1.2	-1.6	-0.2
Heart attack/myocardial infarction (self-reported)	2.0	2.5	5.0	-0.3	-0.3	-0.9	-2.2	-0.3	-0.4	-1.3	2.2	-1.9	-1.7	-1.6	-1.9	-2.2	-2.0	-2.1
Schizophrenia vs Biploar Disorder	1.9	2.5	9.3	3.0	1.7	1.5	1.9	1.9	1.0	1.9	-1.9	0.0	0.0	1.4	1.6	1.8	0.0	0.0
Asthma (self-reported)	1.9	3.9	7.0	0.7	-0.8	-1.7	-2.3	-1.3	-1.4	-2.4	2.2	-2.2	-1.6	-2.3	-2.0	-2.6	-2.0	-2.5
Average weekly beer plus cider intake	1.9	2.8	9.9	1.9	-1.4	1.0	1.3	-0.3	-0.1	1.7	-0.4	3.1	-0.1	2.3	2.5	1.5	0.0	2.6
Reaction Time	1.8	3.4	7.2	0.5	0.4	2.2	2.6	1.0	-0.3	2.2	-1.4	2.0	2.0	2.7	2.1	2.1	1.0	2.5
Hair/balding pattern: Pattern 4	1.8	4.4	9.7	0.7	-0.4	0.5	2.8	1.6	0.1	3.0	-1.5	3.0	1.5	2.9	2.2	2.5	1.5	3.1
Ever had bowel cancer screening	1.8	2.1	8.1	0.3	-0.0	-0.7	-1.3	-0.6	0.8	-1.3	1.4	-1.8	-2.8	-2.0	-0.9	-1.6	-1.9	-1.5
Weight	1.7	8.4	35.5	-0.2	-5.5	0.7	-0.2	-2.9	-6.0	0.8	2.7	4.5	-1.0	2.9	1.4	-0.2	-2.4	2.4
Time employed in main current job	1.7	2.0	8.7	-1.0	-2.2	-1.7	-0.2	-2.6	-2.9	-1.3	0.3	1.2	0.3	0.0	-1.4	0.0	-0.0	0.1
Father’s age at death	1.7	2.3	8.7	-1.5	0.3	0.5	2.0	-0.3	-0.3	0.5	-2.5	1.5	1.6	0.8	0.1	2.1	3.0	1.4
Worrier / anxious feelings	1.7	3.3	9.0	-0.7	0.7	-0.5	-2.2	0.8	1.9	-1.3	1.6	-3.0	-1.2	-2.3	-2.3	-2.2	-1.5	-2.5
Lung cancer (father)	1.7	2.0	5.7	1.3	-0.0	1.8	-0.4	1.7	0.3	1.5	1.9	-0.2	-1.5	1.8	2.4	-0.7	-2.2	0.3
Arm predicted mass (right)	1.7	8.6	38.4	-0.0	-5.7	-0.1	-1.4	-3.3	-6.2	-0.3	3.7	3.2	-1.5	2.0	0.7	-1.5	-3.2	1.1
Trunk fat mass	1.6	6.9	23.7	-0.0	-4.7	1.6	0.8	-2.1	-4.6	1.5	1.3	4.9	0.2	3.2	1.9	1.0	-0.8	3.2
Alzheimer’s Disease (in mother)	1.5	1.8	5.0	1.1	1.6	1.6	0.8	1.8	2.2	1.4	-1.2	0.1	1.2	1.1	1.4	1.1	0.9	0.9
Fasting Glucose	1.5	1.8	3.9	-0.4	-0.1	-0.9	-1.9	-0.1	0.4	-1.5	1.4	-2.0	-0.7	-1.9	-1.0	-1.9	-1.5	-1.6
Hair/balding pattern: Pattern 3	1.5	2.2	5.4	0.5	0.7	-0.3	-1.5	-0.5	1.1	-1.7	1.0	-2.3	-1.4	-2.3	-1.9	-1.7	-0.8	-2.3
Asthma	1.5	3.0	5.6	0.9	-0.6	-1.3	-1.9	-1.1	-1.3	-2.0	2.0	-2.1	-1.7	-2.0	-1.7	-2.4	-1.9	-2.2
Birth weight of first child	1.5	2.8	11.3	-0.8	-2.9	-1.1	-1.9	-2.4	-3.4	-1.0	2.0	1.1	-1.0	0.3	-0.8	-1.2	-1.4	-0.4
Qualifications: O levels/GCSEs or equivalent	1.5	2.4	6.3	0.3	-2.5	-1.9	-1.9	-2.1	-1.3	-1.9	1.9	-0.2	-1.0	-1.1	-0.6	-1.8	-1.3	-1.1
Arm fat-free mass (right)	1.5	7.9	35.7	-0.1	-5.6	0.1	-1.0	-3.2	-6.0	-0.1	3.3	3.4	-1.1	2.3	1.0	-1.1	-2.8	1.4
Whole body fat mass	1.5	6.1	22.0	-0.0	-4.7	1.2	0.4	-2.3	-4.6	1.1	1.6	4.4	-0.2	2.7	1.5	0.5	-1.2	2.6
Leg fat mass (right)	1.5	5.7	21.5	0.0	-4.6	1.1	0.3	-2.5	-4.4	0.9	1.8	4.1	-0.6	2.4	1.2	0.3	-1.6	2.4
Illnesses of father: High blood pressure	1.5	1.8	4.0	-1.0	-1.5	-2.0	-1.6	-1.4	-1.8	-1.6	1.5	-0.1	-0.6	-0.9	-1.3	-1.6	-0.9	-1.1
Basal metabolic rate	1.5	8.6	41.9	-0.3	-5.4	0.2	-0.6	-3.0	-6.5	0.5	3.0	3.8	-1.1	2.8	1.3	-0.7	-2.9	1.9
Arm fat-free mass (left)	1.5	7.7	36.4	0.2	-5.2	0.3	-0.6	-2.8	-6.0	0.4	3.0	3.7	-0.9	2.6	1.3	-0.8	-2.8	1.8
Arm predicted mass (left)	1.5	7.5	34.4	0.0	-5.1	0.3	-0.7	-2.9	-5.9	0.3	3.1	3.5	-1.4	2.4	1.2	-0.9	-2.8	1.7
Bipolar Disorder (2018)	1.4	2.2	6.5	-1.0	-0.5	-1.2	-1.8	-1.5	-0.3	-2.1	1.1	0.0	-1.3	-2.0	-2.5	-1.7	0.0	-2.0
Age at First Birth	1.4	2.0	5.5	-1.6	-0.4	-2.3	-0.6	-1.6	-0.9	-2.2	-0.8	-0.9	0.7	-1.9	-1.9	-0.2	1.2	-1.6
Lupus	1.4	2.1	5.1	-1.9	-0.6	-1.1	-1.5	-1.7	0.9	-1.9	0.7	-1.2	-0.8	-2.3	-1.9	-1.1	-0.2	-1.9
Respiratory disease	1.4	3.1	6.9	2.0	0.4	0.2	-2.0	0.3	-0.3	-1.3	2.4	-2.6	-1.6	-1.4	-0.8	-2.6	-2.5	-2.2
Number of treatments/medications taken	1.4	2.6	6.0	-0.2	-1.6	-1.6	-2.3	-1.1	-1.1	-1.3	2.4	-1.0	-1.4	-1.3	-2.0	-1.9	-2.2	-1.2
Qualifications: CSEs or equivalent	1.4	1.8	3.2	1.0	-1.8	-1.7	-1.6	-1.6	-1.3	-1.2	1.8	0.3	-1.7	-0.8	-0.9	-1.4	-1.1	-0.9
Medication: Ramipril	1.4	1.8	10.0	-0.0	-2.1	-1.0	-0.8	-2.1	-3.2	-0.9	1.3	0.8	-1.3	0.2	-0.0	-0.7	-1.3	-0.1
Happiness	1.4	1.7	5.7	0.8	2.4	1.0	1.6	1.2	1.0	0.9	-2.4	-0.3	0.8	0.6	0.3	1.6	1.6	0.4
Trunk predicted mass	1.4	7.9	40.2	-0.1	-5.2	-0.3	-1.3	-3.1	-6.3	-0.1	3.4	3.0	-1.4	2.2	0.9	-1.3	-3.2	1.1
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	7.0	0.8	0.7	1.3	1.7	1.6	0.4	1.4	-1.2	0.7	2.6	1.2	0.6	1.3	1.6	1.3
Medication: Seretide 50 evohaler	1.4	1.6	5.0	0.9	-2.0	-0.9	-1.3	-1.2	-2.2	-0.5	1.9	0.8	-1.2	-0.3	-0.7	-1.1	-1.4	-0.0
Commuting to job workplace: Car/motor vehicle	1.4	1.6	5.5	1.2	-0.3	1.2	1.5	0.8	-0.0	1.8	-0.4	1.5	-0.1	1.7	2.3	1.2	0.4	1.5
Long-standing illness, disability or infirmity	1.4	2.1	10.0	0.3	-3.2	-0.6	-0.6	-2.5	-2.6	-0.8	1.2	1.9	-0.8	0.2	-0.5	-0.3	-0.5	0.5
Leg fat mass (left)	1.4	5.6	21.3	-0.0	-4.6	1.2	0.1	-2.4	-4.4	0.8	2.0	4.0	-0.7	2.3	1.1	0.1	-1.7	2.3
Ovarian Cancer	1.3	1.8	5.2	-0.9	1.4	-0.9	-1.6	0.9	1.5	-0.5	0.9	-2.3	-1.3	-0.7	-0.5	-1.5	-1.7	-1.9
Blood Platelet Count	1.3	14.7	24.6	3.1	3.4	3.5	4.7	4.5	2.2	5.0	-3.5	2.2	3.9	4.9	4.4	4.0	2.9	3.9
Ever had hysterectomy (womb removed)	1.3	1.5	4.1	1.1	0.5	0.8	1.6	1.1	-0.3	1.6	-0.7	1.2	0.2	1.8	2.0	1.1	0.1	1.7
Leg fat-free mass (left)	1.3	7.1	35.9	-0.8	-4.9	0.1	-0.3	-2.6	-6.0	0.7	2.4	3.7	-0.9	2.8	1.3	-0.2	-2.4	2.0
Trunk fat percentage	1.3	5.4	20.2	0.1	-3.2	2.1	1.6	-1.0	-3.0	2.0	0.1	4.5	1.0	3.1	2.0	1.7	0.4	3.4
Maternal smoking around birth	1.3	1.9	6.6	0.7	-2.0	1.2	0.8	-0.3	-1.6	1.2	0.5	2.6	0.8	1.8	1.1	0.8	-0.3	2.2
Stomach or abdominal pain in last month	1.3	1.6	4.0	0.7	-1.4	-1.5	-1.4	-1.0	-1.6	-1.1	1.7	-0.7	-0.4	-0.4	-1.2	-1.5	-2.0	-1.1
Leg predicted mass (left)	1.3	7.0	34.6	-0.7	-4.8	0.2	-0.2	-2.5	-5.9	0.8	2.3	3.7	-0.8	2.8	1.3	-0.1	-2.3	2.1
Pain all over the body in last month	1.3	1.4	3.2	1.8	0.3	0.8	1.2	1.3	0.9	1.8	-0.1	1.4	-0.4	1.6	1.8	0.8	0.1	1.3
Trunk fat-free mass	1.3	7.7	39.4	-0.0	-5.1	-0.2	-1.2	-3.0	-6.3	-0.1	3.3	3.0	-1.2	2.3	0.9	-1.2	-3.2	1.1
Pulse rate	1.3	2.1	9.7	-0.3	1.8	-0.5	-0.9	1.6	3.1	-0.3	0.8	-2.4	-1.3	-1.0	0.3	-1.2	-1.4	-1.6
Emphysema/chronic bronchitis	1.3	1.4	3.7	-0.4	-0.8	-0.7	-1.1	-1.7	-0.6	-1.7	0.9	-0.9	-0.8	-1.9	-1.7	-1.1	-0.8	-1.4
Smoking status: Previous	1.3	1.9	6.5	0.1	-2.5	-2.4	-0.4	-2.1	-1.1	-0.7	1.4	0.7	-2.0	-0.5	-0.6	-0.6	-1.4	-0.2
Whole body fat-free mass	1.3	7.7	39.4	-0.4	-5.1	-0.0	-0.9	-2.9	-6.3	0.2	3.0	3.4	-1.1	2.5	1.0	-0.9	-2.9	1.5
Leg fat-free mass (right)	1.3	7.0	35.2	-1.0	-4.8	0.0	-0.4	-2.5	-5.9	0.7	2.4	3.5	-0.9	2.7	1.2	-0.4	-2.5	1.9
Osteoarthritis (self-reported)	1.3	1.7	4.8	0.2	-2.1	-0.7	-1.5	-2.2	-1.6	-1.5	1.5	0.6	-1.0	-0.9	-1.4	-1.1	-0.5	-0.4
Whole body water mass	1.3	7.7	39.7	-0.3	-5.1	-0.1	-0.8	-2.9	-6.3	0.2	3.0	3.3	-1.0	2.5	1.1	-0.9	-2.9	1.6
Leg predicted mass (right)	1.3	6.8	34.8	-1.1	-4.7	0.0	-0.5	-2.5	-5.9	0.6	2.4	3.5	-0.9	2.7	1.2	-0.4	-2.5	1.9
Alcohol drinker status: Previous	1.3	1.4	6.1	0.5	-0.5	-1.3	-1.4	-0.1	0.0	-0.2	1.7	-0.6	-2.5	-0.6	-0.1	-1.3	-2.4	-0.5
Ever used hormone-replacement therapy (HRT)	1.2	1.5	3.6	0.2	0.4	1.9	1.5	1.0	1.3	1.6	-0.8	1.1	0.0	1.5	1.7	1.2	0.4	1.5
Sitting height	1.2	8.4	48.5	-0.5	-5.4	-2.8	-1.5	-4.0	-7.0	-1.5	2.7	2.3	-0.7	0.8	-1.0	-1.3	-2.1	0.1
Waist circumference	1.2	4.4	14.4	0.3	-3.5	1.5	0.8	-1.4	-3.5	1.5	1.2	3.8	-0.3	2.9	1.7	0.7	-0.9	2.5
Hair/balding pattern: Pattern 2	1.2	1.5	4.6	-1.4	1.6	1.3	1.3	0.3	1.0	0.5	-2.1	0.6	1.6	0.4	0.4	1.6	1.6	1.0
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	5.4	1.5	-1.5	-0.5	-1.0	-1.1	-2.2	-0.5	1.6	-0.3	-0.9	-0.4	-0.9	-1.0	-2.3	-0.2
Arm fat mass (right)	1.2	4.8	16.7	0.0	-3.8	1.2	0.5	-1.7	-4.1	1.2	1.6	3.7	-0.4	2.6	1.5	0.4	-1.4	2.4
Breastfed as a baby	1.2	1.5	7.8	1.1	2.8	0.2	-0.0	1.8	1.5	0.5	-1.2	-1.7	0.8	-0.3	0.1	0.3	1.1	-1.0
Hypothyroidism/myxoedema (self-reported)	1.2	2.3	4.8	-0.8	-1.9	-1.4	-1.1	-2.1	-1.8	-1.3	1.7	0.1	-2.2	-1.0	-1.4	-1.3	-2.0	-0.8
Medication for pain relief, constipation, heartburn	1.2	2.0	5.7	-0.4	-0.5	0.6	1.9	-0.1	0.1	1.1	-1.5	2.3	1.0	1.5	1.8	1.7	2.4	1.6
Arm fat mass (left)	1.2	4.9	17.0	-0.2	-3.9	1.2	0.4	-1.8	-4.1	1.2	1.7	3.7	-0.6	2.6	1.4	0.3	-1.6	2.4
Average weekly champagne plus white wine intake	1.2	1.7	5.9	1.1	0.6	-0.4	-1.2	-0.8	-0.1	-1.7	0.1	-2.0	-0.3	-2.0	-2.4	-1.0	-0.4	-1.8
Medication: Paracetamol	1.2	1.8	4.2	0.5	-0.4	-0.9	-1.9	-0.6	-0.2	-1.2	1.6	-1.4	-1.3	-1.1	-1.9	-1.6	-2.0	-1.4
Heel bone mineral density (BMD) T-score, automated (right)	1.1	2.5	5.7	-0.8	2.4	2.2	0.9	2.2	1.9	1.5	-1.5	0.1	2.3	0.8	1.1	1.3	1.6	0.7
Falls in the last year	1.1	1.5	4.6	0.4	1.0	2.1	1.5	1.9	0.9	1.9	-1.0	0.5	0.9	1.1	0.6	1.2	0.8	1.1
Pulse wave Arterial Stiffness index	1.1	1.2	4.1	0.9	-1.1	-0.6	-1.2	-0.6	0.2	-0.7	1.7	-0.4	-2.0	-1.0	-0.9	-1.3	-1.7	-0.8
Medication: Amlodipine	1.1	1.5	3.0	-0.7	-0.7	-0.8	-1.4	-0.9	-1.3	-1.7	1.2	-1.2	-0.5	-1.5	-1.7	-1.6	-0.9	-1.3
Body fat percentage	1.1	4.2	16.5	0.1	-3.2	1.8	1.2	-1.4	-2.9	1.5	0.4	4.1	0.6	2.5	1.6	1.3	0.1	2.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	5.3	-1.3	1.6	0.5	1.4	0.8	0.3	0.5	-2.3	-0.4	0.9	-0.1	0.1	1.6	2.0	0.4
Mean time to correctly identify matches	1.1	2.1	4.5	-0.3	-0.3	1.1	2.1	0.1	-0.8	1.5	-1.3	1.9	1.3	2.0	1.4	1.9	1.3	2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	3.9	0.1	-1.4	-1.2	-0.5	-2.0	-1.1	-1.5	-0.1	0.5	-1.3	-1.5	-1.6	-0.3	0.8	-0.7
Supplements: Vitamin C	1.1	1.3	3.6	1.6	1.1	1.3	1.0	1.5	1.9	1.4	-1.0	0.1	-0.6	0.7	1.3	1.0	0.6	0.7
Myopia	1.1	1.6	4.2	-1.4	0.9	-0.1	1.6	0.3	0.9	0.7	-2.0	1.0	2.0	0.4	0.5	1.8	1.9	1.1
Body Mass Index (BMI) (2010)	1.0	1.3	4.8	-0.7	-0.0	0.5	-1.6	0.3	-0.0	-0.6	2.1	0.0	-1.3	-0.9	-0.5	-1.8	-2.2	-1.1
Neuroticism (2016)	1.0	1.4	3.3	0.6	0.7	-0.3	-1.4	0.0	0.8	-1.0	0.6	-1.7	-1.5	-1.7	-1.8	-1.2	-1.1	-1.5
Primary Biliary Cirrhosis	1.0	1.4	7.5	-1.5	-1.5	-0.9	0.1	-2.0	-2.7	-0.9	-0.2	0.0	-1.3	-0.1	-0.9	0.2	0.5	0.4
Height	1.0	19.0	92.5	-1.1	-8.3	-1.6	-1.7	-5.8	-9.6	-0.4	4.1	5.3	-1.8	3.3	1.4	-1.0	-3.9	2.2
Medication: Metformin	1.0	1.4	9.2	1.0	-1.9	-0.3	-0.0	-1.1	-3.0	0.2	0.9	1.2	-0.7	1.0	-0.1	-0.2	-1.0	0.6
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.2	5.2	-1.5	2.2	2.2	0.8	2.0	2.3	1.3	-1.3	-0.1	1.8	0.5	0.7	1.1	1.4	0.4
Chronic bronchitis/emphysema (father)	1.0	1.2	2.6	-1.1	-0.6	-1.6	-1.5	-0.7	0.1	-0.8	1.6	-0.7	-0.9	-0.7	-0.5	-1.4	-1.6	-0.9
Past tobacco smoking	1.0	1.8	6.9	-0.6	2.6	1.9	0.3	1.8	1.1	0.3	-1.8	-1.0	1.9	-0.2	-0.2	0.7	1.7	-0.1
Standing height	1.0	9.7	48.8	0.0	-6.2	-0.4	-0.5	-3.6	-7.0	0.2	2.5	4.3	-0.5	3.1	1.2	-0.2	-1.9	2.0
Exposure to tobacco smoke at home	1.0	1.1	7.4	0.1	-0.8	-0.2	-0.5	-0.1	0.3	0.4	1.7	-0.3	-1.8	0.6	0.9	-0.9	-2.7	-0.0
Pulse wave peak to peak time	1.0	1.2	4.5	-1.0	0.7	0.6	1.1	0.3	-0.7	0.5	-1.5	0.6	2.1	1.0	0.9	1.2	1.7	0.8
Leg pain on walking	1.0	1.2	4.5	-0.7	-1.4	-1.2	-1.2	-1.3	-2.1	-0.7	1.3	0.2	-1.1	-0.3	-0.3	-0.9	-1.5	-0.3
Loneliness, isolation	1.0	1.4	5.5	0.5	1.7	-1.3	-0.7	0.5	2.4	-0.8	-0.3	-1.8	-0.2	-1.3	-1.2	-0.7	-0.4	-1.3
Hearing aid user	1.0	1.1	3.4	0.6	-0.4	0.8	0.6	0.2	-0.4	1.1	0.5	0.7	-1.3	1.6	1.8	0.3	-1.7	1.3
Medication: Omeprazole (e.g. Zanprol)	1.0	1.3	4.4	0.3	-0.6	-1.3	-0.9	-1.5	-1.9	-1.2	0.4	-0.1	-2.1	-1.1	-1.2	-0.5	-0.7	-0.6
Type 2 Diabetes (T2D) (2012)	0.9	1.1	3.3	-0.0	-1.7	-1.5	-0.6	-1.8	-1.8	-1.1	0.6	0.0	-0.4	-0.6	-1.1	-0.7	0.0	-0.4
Diabetes (self-reported)	0.9	1.4	6.3	0.4	-2.0	-0.0	-0.7	-1.3	-2.5	-0.4	1.5	0.8	-1.5	0.3	-0.2	-0.9	-1.4	-0.1
Hip circumference	0.9	3.7	17.8	-0.2	-3.8	0.6	-0.2	-2.2	-4.2	0.2	1.9	2.7	-0.7	1.7	0.4	-0.4	-1.6	1.3
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.9	13.6	0.8	-2.1	-0.1	0.4	-1.3	-3.7	0.2	0.0	2.0	1.1	1.5	0.0	0.6	0.3	1.0
Mood swings	0.9	1.6	4.7	-1.1	0.9	0.7	-1.2	0.5	1.9	-0.7	0.6	-2.2	-0.9	-1.7	-1.4	-1.1	-1.2	-1.5
Breast cancer (self-reported)	0.9	1.0	2.5	-0.2	0.2	0.1	1.0	0.4	0.8	1.0	-1.5	1.1	0.4	1.0	1.5	1.6	1.2	1.5
Unable to work because of sickness or disability	0.9	1.2	3.3	1.8	0.9	1.5	0.9	1.6	1.2	1.7	0.0	0.4	-0.3	1.0	0.9	0.5	-0.8	1.1
Waist Hip Ratio (WHR)	0.8	3.4	10.1	0.6	0.4	1.9	1.5	1.7	0.1	2.6	-0.5	2.3	0.9	3.2	3.1	1.5	0.7	2.5
Smoking Status	0.8	1.9	4.5	1.5	-1.8	0.7	0.1	0.2	0.1	1.5	2.1	1.8	-0.0	2.1	1.9	-0.4	-1.7	1.3
Hand grip strength (left)	0.8	2.1	7.3	0.6	-2.4	-1.8	-1.1	-1.8	-2.7	-1.0	1.8	0.9	-1.4	-0.0	-0.1	-1.2	-1.5	-0.2
Diabetes (mother)	0.8	1.0	2.9	0.5	-1.1	-0.7	1.0	-1.4	-1.7	-0.2	-0.9	1.3	1.1	0.3	-0.2	1.0	1.2	0.8
Average weekly fortified wine intake	0.8	0.9	4.7	2.2	0.6	2.1	0.5	0.9	1.3	0.5	0.2	-0.5	0.7	0.1	0.6	-0.0	0.2	0.0
Had other major operations	0.8	1.0	3.1	-1.6	-1.7	-0.1	-0.2	-1.1	-1.8	-0.4	1.0	1.4	-1.0	0.5	0.2	-0.3	-0.1	0.4
Alcohol intake versus 10 years previously	0.8	1.2	5.2	2.3	-0.5	-1.3	1.0	-0.3	0.0	0.9	-0.7	1.4	-0.8	1.0	1.2	1.1	0.0	1.5
Peak expiratory flow (PEF)	0.8	1.9	15.3	0.4	-2.0	-0.9	-0.3	-0.8	-3.9	0.2	1.2	1.3	-0.3	1.1	0.8	-0.5	-1.3	0.7
Gout (self-reported)	0.8	1.0	2.2	-0.5	0.0	0.9	1.4	0.9	0.1	1.4	-0.8	1.2	0.8	1.5	1.0	1.2	0.8	1.3
Chronic bronchitis/emphysema (mother)	0.8	0.9	8.2	-2.9	-1.2	0.1	-0.0	-0.7	-0.5	0.0	0.7	1.1	-0.8	0.5	0.5	0.1	-0.2	0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	3.6	-1.9	-0.2	-0.9	-0.8	-0.9	0.9	-1.1	-0.2	-0.3	-1.2	-1.4	-1.0	-0.1	0.8	-0.7
Eye problems/disorders: None of the above	0.8	0.9	2.8	0.7	0.2	-0.9	-0.7	-0.8	1.0	-1.1	0.2	-1.2	-1.5	-1.7	-0.4	-0.5	-0.7	-1.3
Neck or shoulder pain in last month	0.8	1.1	3.6	1.4	0.2	1.9	1.2	1.2	-0.2	1.6	-0.5	0.7	0.4	1.1	0.7	1.1	0.0	1.3
Friendships satisfaction	0.8	1.0	4.1	0.5	1.1	-0.3	0.9	0.5	0.1	0.4	-1.9	0.3	1.4	0.7	0.2	1.3	2.0	0.7
Mineral and other dietary supplements	0.8	1.1	3.0	-0.6	1.5	0.1	1.1	1.2	-0.4	1.1	-1.3	0.2	1.7	1.1	0.4	1.2	1.1	0.9
Mother’s age at death	0.8	1.0	3.9	-2.0	1.4	0.3	0.7	0.7	1.0	0.3	-1.4	-0.3	1.4	-0.2	0.1	0.6	1.5	-0.0
Tinnitus: Yes, now most or all of the time	0.8	0.9	2.5	1.5	0.7	0.4	1.0	0.8	1.6	0.8	-1.1	0.2	1.1	0.2	0.1	1.1	1.2	0.8
Supplements: Fish oil (including cod liver oil)	0.8	1.1	3.6	0.5	-1.3	0.2	-0.9	-1.5	-0.1	-1.2	1.0	-0.4	-1.9	-1.2	-0.5	-1.1	-1.1	-1.1
Pack years of smoking	0.8	1.1	3.8	0.1	-0.1	1.1	1.0	0.9	0.4	1.3	-0.5	1.1	1.9	1.5	1.0	1.1	0.6	1.4
Depressed Affect (Nagel 2018)	0.7	1.5	5.3	-0.7	1.9	0.3	-0.9	0.9	2.3	-0.4	-0.1	-2.2	-0.8	-1.7	-1.0	-0.7	0.0	-1.3
Prostate Cancer	0.7	0.9	3.3	0.3	0.5	-1.4	-0.4	-0.0	0.4	-1.1	-0.1	-1.6	0.6	-1.0	-1.8	-0.8	0.1	-1.6
Coronary Artery Disease (CAD)	0.7	0.9	3.2	-1.8	0.3	-0.4	1.5	-0.5	-0.4	0.8	-1.4	0.0	0.0	1.3	0.6	1.6	0.0	0.0
HDL Cholesterol	0.7	1.1	2.7	-0.3	0.5	1.3	1.4	1.1	1.0	1.3	-0.9	0.0	1.2	1.3	1.1	1.1	0.5	1.6
Hypothyroidism (self reported)	0.7	1.7	4.4	-0.6	-1.6	-0.9	-0.9	-1.8	-2.1	-0.9	1.6	0.4	-2.0	-0.2	-0.8	-1.2	-2.0	-0.4
Sensitivity / hurt feelings	0.7	1.2	3.1	-1.1	0.2	-0.4	-1.4	0.7	0.7	-0.5	1.4	-1.8	-0.9	-1.4	-1.1	-1.4	-1.1	-1.3
Hand grip strength (right)	0.7	2.0	6.6	0.4	-2.6	-1.4	-1.2	-1.8	-2.2	-1.2	1.9	0.5	-1.1	-0.2	0.1	-1.4	-1.4	-0.5
Body mass index (BMI)	0.7	2.8	8.9	-0.2	-2.9	1.1	0.1	-1.3	-3.0	0.9	1.6	2.8	-0.7	1.8	1.1	-0.0	-1.6	1.8
Mouth/teeth dental problems	0.7	1.0	4.4	-0.3	0.6	-0.8	-1.1	-0.6	0.4	-1.2	-0.1	-0.9	-2.1	-1.7	-1.3	-0.7	-0.2	-1.0
Impedance of arm (right)	0.7	3.1	8.6	0.4	2.1	0.3	1.9	1.6	2.5	1.1	-2.9	0.2	2.1	0.6	0.5	2.2	2.9	1.1
Arm fat percentage (right)	0.7	2.6	9.4	0.0	-2.2	1.6	1.0	-0.7	-2.2	1.5	0.4	3.1	0.2	2.2	1.4	1.0	-0.4	2.4
Length of working week for main job	0.7	0.8	3.3	0.2	-0.7	1.3	0.1	-0.0	-0.8	0.6	0.3	0.8	0.7	1.8	1.7	0.3	-0.3	1.0
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	4.0	-0.0	0.3	-0.4	2.0	0.6	0.4	0.9	-1.5	1.1	0.8	0.6	0.6	1.5	1.7	1.3
Leg fat percentage (right)	0.7	2.7	10.2	0.6	-3.1	1.4	0.6	-1.7	-2.4	0.7	0.8	3.2	-0.1	1.6	1.1	0.6	-0.6	2.0
Worry too long after embarrassment	0.7	1.2	3.1	-0.7	0.3	0.3	-1.2	0.6	1.3	-0.4	1.0	-1.6	-1.8	-1.2	-1.0	-1.1	-1.1	-1.2
Number of children fathered	0.7	0.8	3.2	0.5	-1.8	-0.3	-0.6	-0.8	-1.2	-0.1	1.4	0.9	-0.9	0.1	0.2	-0.7	-1.3	0.5
Comparative height size at age 10	0.7	4.0	17.5	1.2	-3.6	1.1	-0.1	-1.2	-4.2	1.1	1.4	2.9	0.5	2.9	1.3	0.2	-1.1	1.7
Illnesses of father: Heart disease	0.7	1.0	4.8	1.0	0.7	-0.2	0.0	0.4	1.6	-0.6	-0.7	-0.7	0.9	-1.3	-2.2	-0.0	1.2	-0.7
Arm fat percentage (left)	0.7	2.7	9.8	-0.2	-2.6	1.4	0.8	-1.0	-2.5	1.2	0.6	3.1	0.2	2.1	1.3	0.9	-0.4	2.2
Medication: Aspirin	0.7	0.9	2.6	-0.4	1.6	0.9	0.8	1.2	1.4	0.5	-1.1	-0.9	1.3	-0.2	-0.1	0.7	0.7	-0.0
Illnesses of father: None of the above (group 1)	0.7	0.9	3.5	0.4	0.6	1.3	0.8	0.9	-0.6	1.2	-0.3	0.0	-1.2	1.2	1.9	0.8	-0.3	0.9
Ever taken oral contraceptive pill	0.7	0.7	2.9	0.3	-0.6	1.2	-0.1	-0.3	-1.7	0.6	0.1	1.2	1.0	1.5	0.7	0.4	-0.1	0.9
Leg fat percentage (left)	0.7	2.6	9.3	0.4	-3.0	1.6	0.4	-1.6	-2.3	0.8	0.9	3.1	0.0	1.8	1.1	0.5	-0.9	1.9
Fractured/broken bones in last 5 years	0.7	0.9	2.5	0.9	1.6	-0.4	0.1	1.4	1.2	0.7	0.3	-1.3	-1.4	-0.4	-0.3	-0.1	-1.4	-0.4
Heart disease (siblings)	0.7	0.9	2.7	-1.5	-0.7	0.4	1.0	-0.7	-1.0	0.3	-0.8	1.6	-0.5	0.8	0.6	1.0	1.0	1.2
Neuroticism (Nagel 2018)	0.6	1.5	4.6	-0.8	0.9	-0.2	-1.1	0.5	1.8	-0.7	0.3	-2.2	-1.2	-2.0	-1.7	-0.8	0.0	-1.4
Schizophrenia (2018)	0.6	1.3	5.9	2.4	1.9	1.7	0.6	1.9	1.1	1.1	-0.6	0.0	0.7	0.3	0.7	0.2	0.0	0.3
Breast Cancer	0.6	1.4	5.2	-0.1	2.0	0.7	0.1	2.3	2.3	1.3	-0.4	-0.6	0.9	0.7	1.3	0.4	-0.1	0.4
Mean Putamen Volume	0.6	0.7	6.4	-2.5	-0.1	-0.7	0.5	-0.2	0.5	-0.0	-0.7	0.2	0.7	-0.1	0.4	0.7	0.5	0.6
Schizophrenia (2014)	0.6	1.3	7.2	2.7	1.6	1.5	0.5	1.8	1.2	1.1	-0.5	0.0	0.6	0.7	0.8	0.1	0.0	0.3
BMI	0.6	3.3	13.0	-0.4	-2.7	0.4	-0.4	-1.3	-3.6	0.6	2.5	2.1	-1.7	1.5	1.3	-0.9	-2.6	1.1
Systolic Blood Pressure	0.6	3.0	6.6	-0.0	2.0	0.5	2.1	1.8	2.1	1.5	-2.2	0.7	2.6	1.1	1.4	2.0	2.2	1.3
Neuroticism	0.6	1.5	3.7	-0.3	0.9	0.4	-1.4	1.0	1.3	-0.3	1.2	-1.9	-1.6	-1.4	-1.1	-1.4	-1.6	-1.2
Average weekly spirits intake	0.6	0.7	1.7	-0.0	-0.6	-0.0	-1.3	-0.4	-1.3	-0.9	0.9	-0.5	-0.6	-1.0	-1.1	-1.0	0.1	-0.9
Frequency of depressed mood in last 2 weeks	0.6	0.8	2.9	-0.3	1.4	0.6	0.5	1.6	1.7	0.8	-0.3	-0.7	1.5	0.6	0.5	0.1	-0.4	0.2
Current tobacco smoking	0.6	1.0	2.6	1.3	-0.3	1.6	0.3	1.1	1.2	1.0	0.9	0.9	0.8	1.4	1.2	-0.2	-0.3	0.7
Serious illness, injury or assault to yourself	0.6	0.7	3.2	0.2	-1.6	-0.6	-0.7	-1.3	-1.8	-0.5	0.8	0.2	-0.4	0.1	-0.5	-0.4	-0.6	-0.4
Multivitamins +/- minerals	0.6	0.8	1.6	0.9	-1.2	-0.1	-1.1	-0.8	-0.2	-0.9	1.3	-0.1	-0.8	-1.0	-0.9	-1.0	-0.9	-0.8
Number of incorrect matches in round	0.6	1.1	3.8	-0.3	1.7	-0.2	-0.8	1.2	1.8	-0.3	0.0	-1.9	-0.1	-0.9	-0.9	-0.6	-0.4	-1.2
Had menopause	0.6	0.7	3.1	-1.8	0.7	0.1	0.6	0.6	1.7	0.3	-1.0	0.1	0.6	-0.2	0.3	0.7	1.2	0.2
Forced vital capacity (FVC)	0.6	2.5	12.6	1.3	-1.7	0.5	0.4	-0.2	-3.5	1.1	1.0	1.8	0.6	2.5	1.7	0.2	-1.4	1.5
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	3.2	-0.1	0.4	-0.9	-0.7	-0.7	0.3	-1.2	-0.3	-1.2	-0.2	-1.2	-1.8	-0.5	-0.0	-1.4
Financial difficulties in last 2 years	0.6	0.8	2.7	0.3	-1.6	-0.4	-0.7	-1.1	-1.5	-0.4	1.2	1.0	-0.8	0.7	0.4	-0.7	-0.5	0.1
Illnesses of siblings	0.6	0.8	2.8	1.3	1.5	0.6	-0.6	0.7	0.9	-0.4	-0.4	-1.7	1.0	-0.9	-0.6	-0.4	0.2	-1.1
Forced expiratory volume in 1-second (FEV1)	0.6	1.9	9.5	1.0	-1.5	0.4	0.5	-0.1	-3.1	1.0	0.7	1.5	0.5	2.3	1.6	0.2	-1.2	1.2
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	4.0	-2.0	0.2	1.3	0.3	-0.0	-0.2	0.0	-0.8	0.4	1.4	0.5	0.0	0.6	0.9	0.3
Number of full sisters	0.6	0.7	3.4	1.9	-0.5	0.9	0.9	-0.1	-0.3	0.5	0.0	0.8	0.9	1.3	0.7	0.5	-0.4	0.9
Overall health rating	0.6	1.2	6.0	0.3	-1.4	-0.6	-1.0	-0.8	-2.4	-0.2	1.3	0.4	-0.6	0.1	-1.1	-0.8	-2.0	-0.0
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	1.6	-0.6	0.2	-1.0	-1.3	0.9	0.8	-0.1	1.1	-1.1	-0.4	-0.8	0.2	-1.1	-0.9	-0.7
Medication: Aspirin	0.6	0.8	2.7	-0.7	1.6	0.8	0.4	1.1	1.5	0.2	-0.9	-1.3	1.1	-0.6	-0.3	0.3	0.5	-0.4
Illnesses of siblings: Diabetes	0.6	0.8	3.5	0.0	-1.1	-0.7	-0.3	-0.5	-1.3	0.2	1.3	0.8	-1.9	0.7	0.1	-0.5	-1.1	0.4
Diabetes diagnosed by doctor	0.6	0.9	5.3	0.1	-1.5	-0.3	-0.4	-1.0	-2.3	-0.1	1.2	0.6	-1.4	0.2	-0.3	-0.7	-1.2	-0.1
Medication: Gliclazide	0.6	0.7	1.8	0.7	-1.2	0.4	0.9	-0.0	-0.7	0.9	0.3	1.2	-0.2	1.2	1.3	0.5	-0.6	1.2
Wears glasses or contact lenses	0.6	0.6	3.1	0.6	1.0	1.8	1.0	0.7	0.6	0.9	-0.9	0.1	-0.3	0.4	0.6	0.8	0.4	0.4
Financial situation satisfaction	0.6	0.7	2.9	1.0	-1.1	0.7	0.6	-0.8	-0.8	0.4	0.0	1.7	-0.1	1.3	0.9	0.4	0.1	1.1
Depression (Nagel 2018)	0.5	0.8	2.9	-0.6	1.4	0.0	-0.7	1.5	1.5	0.4	0.5	-1.7	0.3	-0.4	0.3	-0.8	0.0	-0.6
Crohns Disease (2017)	0.5	1.1	4.0	0.8	-1.5	-0.3	0.4	-0.7	-1.1	0.6	0.5	2.0	-0.9	1.7	1.0	0.2	0.0	1.4
Irritable Bowel Disease (IBD)	0.5	1.3	3.6	0.7	-1.6	0.3	0.6	-0.7	-1.5	0.7	0.7	1.9	-1.3	1.8	1.3	0.2	0.0	1.4
Crohns Disease (2012)	0.5	0.8	3.7	0.1	-1.2	-1.3	-0.7	-1.9	-1.2	-1.2	0.3	0.0	-0.5	-0.4	-1.2	-0.6	0.3	-0.3
Triglycerides	0.5	0.9	1.9	-0.8	-1.3	-0.3	-1.0	-1.4	-1.2	-0.9	1.3	0.0	-0.7	-0.2	-0.0	-1.0	-1.3	-0.6
Heel T-Score	0.5	3.9	15.0	0.6	3.9	1.8	1.2	2.9	3.6	1.1	-2.3	-1.4	1.8	-0.4	0.4	1.3	1.8	0.1
Type 2 Diabetes (T2D) (2018)	0.5	0.9	4.0	0.2	-1.3	-1.4	-0.6	-1.3	-2.0	-0.8	0.5	0.1	-0.1	-0.2	-1.2	-0.6	-0.4	-0.5
Relative age of first facial hair	0.5	0.9	3.0	-0.2	0.5	-0.0	1.5	0.6	-0.5	1.1	-0.9	0.9	0.8	1.3	0.9	1.2	0.5	1.7
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.7	0.0	-0.2	1.2	0.6	-0.8	-1.3	0.0	-1.1	0.7	0.5	0.3	-0.5	1.1	1.1	0.5
Medication for hormone replacement therapy	0.5	0.5	1.3	0.9	-0.1	0.7	0.9	0.2	-0.7	0.9	-0.2	0.8	0.4	1.1	0.7	0.7	-0.2	1.1
Severe depression (siblings)	0.5	0.6	2.2	0.0	-0.7	0.2	-0.7	0.1	-0.7	0.1	1.5	0.1	-1.5	0.1	0.0	-0.8	-1.4	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	3.0	0.1	1.7	0.4	0.3	1.6	1.4	0.7	-0.5	-0.9	1.0	0.2	0.5	0.1	-0.4	-0.1
Medication: Levothyroxine sodium	0.5	0.9	2.7	-0.5	-1.5	-0.8	-0.2	-1.1	-1.0	-0.4	1.3	0.7	-1.5	-0.2	-0.3	-0.8	-1.6	0.1
Nervous feelings	0.5	0.9	3.9	-0.6	1.0	-0.7	-0.4	0.7	2.0	-0.3	-0.6	-0.9	0.3	-1.6	-1.2	-0.1	0.7	-0.7
Qualifications: None of the above	0.5	1.0	2.0	0.1	1.1	1.3	1.2	1.2	1.4	1.4	-0.8	0.6	0.7	1.0	0.4	1.1	0.3	1.1
Medication: Paracetamol	0.5	0.8	2.1	0.2	0.3	-0.5	-1.4	0.0	0.4	-0.7	0.9	-1.4	-0.2	-0.7	-1.5	-1.0	-1.4	-1.0
Glaucoma (self-reported)	0.5	0.6	2.2	0.3	0.2	1.5	0.4	0.9	0.2	0.7	-0.3	0.7	1.5	0.9	0.1	0.4	1.0	0.7
Age at first live birth	0.5	1.0	3.0	-1.7	0.2	-1.7	-0.3	-0.4	0.0	-1.0	-0.8	-0.7	1.1	-1.0	-1.0	-0.0	1.4	-1.0
Health satisfaction	0.5	0.7	3.3	-0.2	-0.9	-1.2	0.3	-1.4	-1.8	-0.1	-0.4	1.0	-0.4	0.5	-0.1	0.5	-0.4	0.6
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.3	-0.0	1.5	-0.1	0.4	0.8	1.2	0.2	-0.8	-0.9	1.4	-0.6	-0.2	0.3	0.7	-0.8
Migraine (self-reported)	0.5	0.6	3.3	-0.3	0.5	-1.8	-1.0	-0.0	0.9	-0.7	0.1	-1.0	-0.5	-0.8	-0.7	-0.7	-0.6	-0.6
Alcohol intake frequency.	0.5	1.1	4.1	1.4	2.0	0.2	0.1	2.0	1.5	0.9	-0.7	-1.0	0.8	0.4	0.0	0.4	-0.4	0.4
Back pain experienced in last month	0.5	0.7	2.5	0.2	-0.6	0.9	0.9	-0.8	-1.6	0.3	-0.5	1.1	1.1	0.8	-0.2	0.8	-0.2	0.9
Smoking status: Current	0.5	0.8	2.4	1.0	-0.4	1.6	0.3	0.9	0.8	1.0	0.9	0.9	0.8	1.4	1.2	-0.2	-0.3	0.6
Guilty feelings	0.5	0.7	3.4	-0.8	1.0	0.6	0.0	1.8	1.3	1.3	-0.2	-0.4	-0.0	0.7	0.9	0.3	-0.7	0.7
Risk taking	0.5	0.8	3.2	0.3	0.9	0.1	0.8	0.7	0.4	0.4	-1.5	0.3	1.2	-0.0	-0.2	1.2	1.8	0.9
Ever depressed for a whole week	0.5	0.6	1.7	-0.5	0.9	-0.4	0.2	0.0	1.0	-0.6	-1.1	-0.7	0.4	-1.1	-1.3	0.2	1.0	-0.7
Worry (Nagel 2018)	0.4	0.9	4.0	0.3	0.5	-0.5	-0.5	-0.0	1.5	-0.7	-0.5	-1.0	-0.6	-2.0	-1.8	-0.1	0.0	-0.8
Ulcerative Colitis (UC)	0.4	0.8	2.2	0.5	-1.2	0.6	0.6	-0.3	-1.2	0.7	0.3	1.3	-1.3	1.5	1.1	0.4	0.0	0.9
Major Depression (MDD)	0.4	0.5	1.6	-0.4	0.3	0.4	-0.2	-1.3	0.1	-0.7	-1.0	0.0	1.1	-0.5	-0.9	0.5	0.9	-0.0
Verbal and Numeric Reasoning (VNR)	0.4	1.0	2.4	-1.3	1.1	1.2	0.8	1.1	0.7	0.8	-1.1	-0.1	1.6	1.2	1.2	1.0	0.7	0.7
Ulcerative Colitis	0.4	0.5	4.6	0.6	-1.2	0.1	0.0	-0.8	-2.1	-0.2	0.4	0.0	0.1	0.8	-0.2	-0.0	0.1	0.2
Blood Eosinophil Count	0.4	3.2	7.6	2.8	2.2	2.1	2.1	2.4	1.0	2.5	-1.2	0.3	0.5	1.9	2.0	1.5	-0.4	1.5
Vitamin and mineral supplements	0.4	0.5	4.7	-2.2	0.5	-1.0	-0.0	0.0	-0.3	-0.3	-0.3	-0.4	0.8	0.1	-0.2	-0.0	0.1	-0.0
Supplements: Zinc	0.4	0.4	1.7	-1.2	-0.5	-1.3	-0.1	-0.7	0.6	-0.8	-0.2	0.2	-0.6	-0.7	-0.4	-0.2	0.5	-0.1
Neuroticism score	0.4	0.8	3.7	-0.2	1.2	0.5	-0.4	1.4	1.9	0.3	0.3	-1.4	-0.6	-0.9	-0.5	-0.5	-0.9	-0.6
Mouth/teeth dental problems: Dentures	0.4	0.7	2.0	-0.2	-0.6	-0.8	0.9	0.1	-0.3	0.9	-0.2	0.9	0.9	1.4	1.4	0.7	0.4	0.9
Depression (self-reported)	0.4	0.5	1.5	0.3	1.0	1.2	0.2	1.0	1.2	0.5	-0.4	-0.9	0.3	-0.3	-0.9	0.2	0.2	-0.5
Medication: Lansoprazole	0.4	0.5	1.5	0.1	0.3	0.4	-1.0	0.9	-0.1	-0.0	1.2	-0.9	-0.3	-0.2	-0.2	-1.2	-0.9	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	4.1	0.6	-1.0	0.6	-0.2	0.4	-2.0	0.8	1.6	0.6	-0.2	1.7	1.1	-0.6	-1.9	0.4
Impedance of arm (left)	0.4	1.8	6.4	0.6	1.5	0.2	1.3	1.1	2.1	0.6	-2.3	-0.1	1.6	0.1	0.1	1.6	2.5	0.5
Tense / ‘highly strung’	0.4	0.6	2.8	0.4	0.7	-0.2	-0.2	-0.0	1.0	-0.6	-0.5	-0.9	-0.0	-1.7	-1.4	-0.0	0.4	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	1.4	-1.1	1.0	0.8	0.0	0.5	0.7	0.0	-0.4	-1.0	-1.1	-1.2	-1.2	0.1	-0.1	-0.5
Pulse wave reflection index	0.4	0.5	1.2	0.6	-1.0	-0.2	-0.7	-0.7	-0.2	-0.4	1.1	0.1	-0.5	-0.5	-1.0	-0.7	-1.1	-0.0
Forced vital capacity (FVC), Best measure	0.4	1.5	4.9	0.4	-1.2	0.7	-0.2	0.5	-2.2	1.0	1.7	0.8	0.0	1.9	1.3	-0.6	-2.0	0.7
Comparative body size at age 10	0.4	1.0	4.4	0.1	1.5	1.7	0.5	1.5	2.1	0.8	-0.3	-0.5	-0.3	-0.1	1.2	0.2	-0.2	0.2
Number of full brothers	0.4	0.5	1.2	0.4	-0.6	-1.1	-0.5	-0.3	-0.5	-0.4	1.1	-0.3	-0.9	-0.7	-0.9	-0.9	-0.3	-0.7
Qualifications: College or University degree	0.4	1.2	4.9	-0.9	1.4	0.6	1.1	0.3	-0.1	-0.1	-2.2	-0.5	1.7	0.0	-0.5	1.3	2.0	-0.1
Medication: Allopurinol	0.4	0.5	1.7	-0.5	0.1	0.5	0.8	0.9	-0.0	1.3	-0.0	0.6	-0.3	1.1	0.9	0.6	-0.7	1.0
Medication: Omeprazole	0.4	0.4	2.8	1.1	-0.5	-0.5	0.0	-0.9	-1.7	-0.4	-0.1	0.3	-0.8	-0.2	-0.6	0.2	-0.1	0.1
Had major operations	0.4	0.5	2.3	1.2	-0.6	-0.3	-0.4	-0.8	-1.5	-0.6	0.6	-0.2	0.3	0.3	-0.3	-0.6	-0.3	-0.8
Age at last live birth	0.4	0.6	1.7	0.3	0.5	-0.6	1.3	0.2	0.7	0.4	-1.3	0.6	0.2	0.1	0.4	1.1	1.2	0.7
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.6	0.4	1.0	-0.3	-0.4	0.5	1.2	-0.3	0.0	-1.1	-0.5	-1.3	-0.6	-0.5	-0.3	-0.9
Handedness (chirality/laterality): Left-handed	0.4	0.5	4.1	-2.0	0.3	0.5	-0.5	0.7	0.5	0.4	0.7	0.2	-0.3	0.3	0.6	-0.3	-0.6	0.4
Commuting to job workplace: Walk	0.4	0.5	1.8	1.0	0.4	1.0	0.0	1.0	0.5	0.5	0.4	-0.3	0.1	0.5	1.3	-0.3	-0.9	0.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.9	1.2	-0.5	0.5	1.1	0.2	-1.4	0.8	0.1	0.6	1.1	1.0	0.6	0.4	-0.1	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.5	-1.2	1.1	1.2	-0.2	0.7	1.1	0.3	-0.1	-0.8	0.1	0.1	0.4	-0.0	-0.4	-0.3
Miserableness	0.4	0.7	4.1	-0.5	0.8	0.4	-0.6	0.8	2.0	0.1	0.6	-1.0	-0.9	-0.7	-0.1	-0.6	-1.1	-0.6
High cholesterol (Self-reported)	0.4	0.7	1.3	1.0	0.8	1.0	0.5	1.1	0.2	1.1	-0.6	0.5	1.2	0.9	0.8	0.8	0.3	0.9
Medication: Atorvastatin	0.4	0.5	2.2	-0.7	1.1	0.5	-0.4	0.1	0.8	-0.7	-0.5	-1.5	0.6	-0.5	-0.2	-0.2	-0.1	-1.1
Ever smoked	0.4	0.7	2.9	1.0	-1.7	-1.0	0.0	-1.4	-0.4	-0.2	1.1	0.8	-0.7	0.5	0.2	-0.4	-0.8	-0.0
Basal cell carcinoma (self-reported)	0.4	0.4	1.2	-0.7	0.7	0.3	-0.6	0.8	1.1	0.0	0.2	-1.1	-0.4	-1.1	-0.2	-0.4	-0.1	-0.7
Impedance of whole body	0.4	2.3	8.0	1.2	1.6	0.6	1.3	1.3	2.6	0.5	-2.2	-0.1	2.1	-0.0	0.0	1.5	2.8	0.4
Bipolar Disorder or Schizophrenia	0.3	0.6	1.6	1.3	1.1	0.6	-0.7	0.6	0.6	-0.5	0.2	0.0	-0.7	-1.1	-0.9	-0.9	-0.2	-1.1
LDL Cholesterol	0.3	0.5	1.2	-0.2	-0.8	-0.8	-0.6	-1.1	-0.8	-0.7	0.6	0.0	-1.1	-0.4	-0.5	-0.5	-0.7	-0.5
Blood Red Count	0.3	3.3	12.8	1.1	-2.3	1.2	1.2	-0.6	-2.1	1.8	0.7	3.6	-1.6	2.2	2.0	1.0	-0.6	2.7
Lung FEV1/FVC ratio	0.3	1.3	4.3	-0.4	-1.0	1.3	1.0	0.4	-0.1	1.6	0.1	2.1	-0.0	2.0	1.4	0.8	0.2	1.7
Lung FVC	0.3	1.8	5.6	1.4	2.1	1.2	1.3	2.4	1.7	1.6	-0.6	-0.4	0.9	1.1	1.4	0.7	-0.3	0.8
Tanning	0.3	4.0	9.1	1.5	-1.8	-2.1	-2.6	-1.6	-1.0	-1.9	2.8	-1.2	-2.1	-1.3	-1.0	-2.7	-3.0	-1.9
Systolic blood pressure, automated reading	0.3	1.0	3.2	-0.5	1.2	1.2	1.2	0.9	1.8	0.9	-1.1	0.4	0.6	0.5	0.9	1.0	1.0	0.6
Medication: Co-codamol	0.3	0.4	2.3	-0.2	-1.5	-0.1	0.1	-0.5	-0.7	0.4	0.7	0.8	0.1	0.7	0.2	0.1	-0.7	0.5
Pack years adult smoking proportion	0.3	0.4	2.1	0.1	-0.5	0.6	0.3	0.5	0.1	0.8	0.2	0.8	1.4	1.0	0.6	0.4	0.1	0.8
Impedance of leg (right)	0.3	1.5	5.7	1.7	1.2	0.5	0.8	0.5	1.9	-0.2	-1.7	-0.2	1.7	-0.5	-0.5	1.0	2.4	-0.1
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.6	0.0	0.6	1.0	0.3	0.4	1.1	0.3	-0.2	-0.2	1.2	0.5	0.8	0.3	-0.1	0.2
Medication: Atenolol	0.3	0.3	1.1	-1.1	-0.6	0.9	-0.1	-0.1	-0.5	0.4	0.4	0.7	0.9	0.6	0.5	0.0	-0.0	0.3
High blood pressure (mother)	0.3	0.4	1.8	-0.6	-0.2	-0.8	0.1	-0.1	-0.5	-0.0	-0.7	0.7	1.0	-0.2	-0.1	0.5	1.4	0.5
Impedance of leg (left)	0.3	1.3	4.4	1.4	1.2	0.7	0.6	0.7	2.0	-0.1	-1.5	-0.3	1.8	-0.4	-0.5	0.8	2.1	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.9	-0.4	-0.0	-1.4	-0.4	-0.1	-0.6	-0.3	0.1	-0.7	-0.6	-0.5	-1.1	-0.3	-0.8	-0.6
Hearing difficulty/problems with background noise	0.3	0.6	1.9	-0.1	-0.8	-0.4	0.9	-0.4	-1.3	0.7	-0.0	1.2	-0.3	0.7	0.0	0.7	-0.4	1.4
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.5	-0.4	0.5	-1.0	-0.0	0.0	0.8	-0.7	-0.2	-1.0	-0.1	-1.2	-0.8	-0.3	0.4	-0.7
Medication: Simvastatin	0.3	0.4	1.5	-0.0	-0.9	1.0	-0.9	-0.6	-1.2	-0.1	0.8	0.5	-0.3	0.3	-0.4	-0.5	-0.6	-0.0
Qualifications: A levels/AS levels or equivalent	0.3	0.6	5.0	-0.9	-0.5	0.4	0.0	-0.4	-0.2	-0.5	-0.7	0.1	2.2	0.0	0.4	0.3	1.1	0.0
Illnesses of mother	0.3	0.3	1.7	0.9	-0.0	0.9	-0.2	0.1	0.4	-0.1	0.6	-0.3	-1.3	-0.2	-0.3	-0.5	-0.7	-0.4
Ever highly irritable/argumentative for 2 days	0.3	0.4	2.8	1.7	0.4	0.3	-0.6	0.2	0.4	-0.1	0.3	-0.5	-0.9	-0.5	-0.4	-0.5	-0.8	-0.3
Loud music exposure frequency	0.3	0.3	0.9	-0.2	0.9	0.3	0.3	0.8	0.8	0.2	0.2	-0.9	-0.3	-0.1	-0.1	-0.2	-0.7	-0.5
Headache pain in last month	0.3	0.6	2.9	-0.5	1.5	-0.1	-0.0	1.7	0.7	0.8	-0.4	-0.7	1.0	0.8	0.1	0.0	-0.2	0.1
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.9	-0.4	0.1	0.4	-0.7	0.1	-0.3	-0.2	0.8	-0.7	-0.8	-0.6	-0.5	-0.7	-1.4	-0.3
High blood pressure (siblings)	0.3	0.4	0.9	-0.9	-0.9	-0.1	0.3	-0.2	-0.2	0.4	0.4	0.9	0.2	0.9	0.9	0.3	-0.4	0.8
Wheeze or whistling in the chest in last year	0.3	0.5	2.8	0.2	-1.2	-0.3	0.1	-1.0	-1.7	0.0	0.1	1.2	-0.5	0.5	-0.4	0.3	0.0	0.4
Pulse rate, automated reading	0.3	1.1	6.6	0.7	1.3	0.5	0.8	1.8	2.6	1.1	-0.7	-0.1	0.4	0.4	0.9	0.7	0.4	0.5
Suffer from ‘nerves’	0.3	0.5	2.0	-1.4	-0.5	-0.4	0.8	-0.4	0.4	0.1	-0.9	0.9	0.4	-0.6	-0.7	0.9	0.9	0.6
Knee pain experienced in last month	0.3	0.5	1.3	-1.1	-1.1	0.7	-0.1	-0.3	-0.8	0.4	0.8	1.1	-0.6	0.5	-0.4	-0.1	-0.7	0.7
Average weekly red wine intake	0.3	0.4	1.2	0.6	0.6	1.1	0.1	1.1	0.7	0.8	-0.1	-0.1	0.6	0.5	1.0	0.2	-0.0	0.2
Qualifications: nursing, teaching	0.3	0.4	1.5	-0.4	0.9	1.2	0.7	1.1	0.0	0.9	-0.5	-0.1	-0.0	0.6	0.8	0.4	-0.1	0.3
Eye problems/disorders: Cataract	0.3	0.4	1.2	-1.0	0.3	0.2	-0.3	0.9	0.1	0.6	0.7	-0.7	0.1	0.6	0.4	-0.4	-1.1	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	2.7	0.0	1.2	1.7	0.5	1.2	1.2	0.7	-0.2	-0.8	-0.6	0.2	0.1	0.2	-0.6	-0.0
Commuting to job workplace: Public transport	0.3	0.4	1.3	-1.1	0.1	-0.4	0.4	-0.7	0.1	-0.6	-1.0	-0.3	0.8	-0.3	-0.2	0.5	0.9	-0.3
Medication: Bendroflumethiazide	0.3	0.5	1.4	0.5	1.0	-0.6	-0.6	0.6	0.7	-0.4	-0.1	-1.2	0.6	-0.7	-0.7	-0.5	0.2	-0.9
Irritability	0.3	0.4	1.5	1.2	-0.1	1.0	-0.1	0.6	0.6	0.5	0.8	-0.4	-0.6	0.4	0.5	-0.4	-1.2	0.0
Pain experienced in last month	0.3	0.5	1.7	-0.8	0.9	0.2	0.4	0.8	1.3	0.3	-0.5	-0.2	0.8	-0.1	1.0	0.3	1.1	0.2
Supplements: Calcium	0.3	0.3	1.0	0.8	0.7	0.8	-0.1	0.8	0.7	-0.1	0.3	-1.0	-0.1	-0.2	-0.1	-0.5	-0.3	-0.7
Bipolar Disorder (2011)	0.2	0.2	0.8	0.6	0.9	0.9	0.2	0.7	0.0	0.6	-0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Rheumatoid Arthritis	0.2	0.2	0.7	-0.8	-0.8	-0.5	0.0	-0.3	-0.3	0.1	0.4	0.0	-0.8	-0.0	-0.1	-0.1	-0.7	0.4
Blood White Count	0.2	1.1	5.8	2.4	0.4	0.5	1.4	1.0	0.1	1.4	-0.2	0.8	0.3	1.2	1.2	0.7	-0.5	1.2
Cardiovascular Disease	0.2	0.6	2.0	0.1	1.3	0.8	-0.0	1.2	0.8	0.7	-0.5	-0.4	1.4	0.9	0.6	0.2	0.1	0.2
Chronotype (morning person)	0.2	0.4	1.5	-0.3	-0.6	-0.7	-0.4	0.1	-0.5	0.4	0.9	0.3	-1.0	0.6	1.2	-0.4	-0.9	0.2
Hearing difficulty/problems: Yes	0.2	0.3	2.0	-1.4	-0.1	-1.0	0.5	-0.5	-0.8	-0.1	-0.4	0.5	0.3	-0.1	-0.2	0.3	0.1	0.6
Diabetes (father)	0.2	0.3	0.8	0.9	-0.9	0.1	-0.2	-0.4	-0.6	0.2	0.2	0.9	0.5	0.8	0.2	0.1	-0.1	0.5
Townsend deprivation index at recruitment	0.2	0.3	1.2	-0.4	0.8	-0.0	0.3	0.5	0.2	0.4	-0.3	-0.1	1.1	0.9	0.5	0.3	-0.2	0.4
Fed-up feelings	0.2	0.4	1.3	-1.1	0.8	0.2	-0.2	0.5	0.7	-0.0	0.0	-1.0	0.2	-0.5	-1.1	-0.3	-0.7	-0.7
Relative age voice broke	0.2	0.3	1.4	-0.1	-0.8	-1.1	-0.1	-0.8	-1.2	-0.4	0.5	0.2	0.3	0.0	-0.5	-0.2	-0.2	0.3
Age when periods started (menarche)	0.2	0.5	2.5	-0.2	-1.5	-0.6	-0.0	-1.6	-0.8	-0.8	0.1	0.7	-0.3	-0.4	-0.2	0.1	0.3	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	1.0	-1.0	0.2	0.4	-0.6	0.5	-0.0	-0.3	0.5	-1.0	0.4	-0.4	-0.8	-0.8	-0.7	-0.7
Number of live births	0.2	0.2	1.2	1.1	-0.3	0.1	0.5	-0.2	-0.8	-0.0	0.2	0.4	-1.0	-0.3	0.0	0.1	-0.1	0.3
Medication: Cholesterol lowering	0.2	0.3	1.3	0.6	-0.1	1.1	-0.8	-0.2	-0.5	-0.1	0.6	-0.3	0.1	0.1	-0.2	-0.5	-0.9	-0.5
Prospective memory result	0.2	0.2	1.6	0.0	0.1	-1.3	0.1	0.5	0.6	0.5	0.3	0.1	-0.5	0.3	0.6	-0.0	-0.3	0.2
Birth weight	0.2	0.5	3.1	0.3	-1.1	0.1	-0.3	-1.4	-1.8	-0.6	0.2	0.7	0.4	0.1	-0.5	-0.0	-0.1	0.1
Exposure to tobacco smoke outside home	0.2	0.3	1.1	-0.8	-0.1	0.3	-1.0	0.5	-0.3	-0.0	0.8	-0.4	0.6	-0.1	-0.4	-0.7	-0.6	-0.3
Shortness of breath walking on level ground	0.2	0.3	2.4	0.6	-0.7	-1.5	-0.0	-0.5	-0.3	-0.1	0.2	0.2	-0.5	-0.1	-0.4	-0.1	-0.1	-0.1
Angina (self-reported)	0.2	0.3	1.7	1.3	0.4	-0.0	-0.6	0.3	0.0	-0.2	0.2	-0.8	0.1	-0.1	-0.3	-0.5	-0.2	-0.8
Family relationship satisfaction	0.2	0.3	1.3	-1.2	-0.2	-0.3	0.3	-0.2	0.8	0.2	-0.5	0.7	-0.6	0.2	0.5	0.4	0.3	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	1.1	1.0	0.5	0.9	0.4	0.5	-0.5	0.2	-0.3	-0.2	-0.3	0.2	0.3	0.2	0.3	0.0
Medication for cholesterol	0.2	0.3	1.1	-0.8	-0.3	-0.6	-0.6	-0.7	0.0	-0.6	0.2	-0.1	-1.0	-0.5	-0.1	-0.4	-0.4	-0.4
Number of self-reported non-cancer illnesses	0.2	0.3	1.0	0.3	-0.6	-0.3	-0.4	-0.8	-0.8	-0.9	0.4	-0.4	-0.2	-0.6	-1.0	-0.5	0.1	-0.5
Eye problems/disorders: Glaucoma	0.2	0.3	1.8	-0.2	0.3	1.3	-0.2	1.0	0.4	0.5	0.3	-0.1	0.7	0.5	0.1	-0.2	0.2	0.1
Medication: Lisinopril	0.2	0.3	0.8	-0.9	0.2	0.8	-0.4	0.9	0.2	0.6	0.8	-0.1	0.2	0.6	0.4	-0.5	-0.8	0.1
Diastolic blood pressure, automated reading	0.2	0.6	1.7	1.0	-0.3	0.4	1.0	0.2	0.9	0.6	-0.6	1.3	0.2	0.3	0.6	0.8	0.9	0.9
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.0	-0.5	-0.1	0.0	-0.8	-0.8	-0.5	-0.9	0.6	-1.0	-0.2	-0.3	-0.6	-0.7	0.0	-1.0
Allergy or Eczema	0.1	0.1	1.0	0.3	0.6	-0.3	0.0	-0.0	1.0	-0.2	-0.3	-0.3	-0.0	-0.4	0.1	-0.0	-0.4	-0.2
Angina	0.1	0.2	1.0	1.0	0.3	0.2	-0.6	0.3	-0.1	-0.1	0.2	-0.7	0.2	0.1	-0.1	-0.4	-0.3	-0.6
Taking other prescription medications	0.1	0.2	0.6	0.7	-0.2	0.2	0.3	0.5	-0.3	0.8	0.2	0.6	0.1	0.6	-0.0	0.4	0.1	0.7
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.2	-0.1	-0.3	-0.4	-0.3	-0.3	-0.4	-0.3	0.2	-0.2	-0.0	-0.4	0.1	-0.3	0.0	-0.4
High blood pressure	0.1	0.2	0.7	0.2	0.4	0.7	-0.5	0.3	0.2	-0.1	0.5	-0.8	-0.2	-0.1	-0.2	-0.5	-0.5	-0.7
Supplements: Glucosamine	0.1	0.2	0.8	-0.3	-0.4	-0.2	0.3	-0.2	-0.4	0.1	-0.6	0.5	0.4	0.2	-0.3	0.6	0.9	0.2
Allergy	0.1	0.2	0.7	-0.8	0.2	0.3	-0.0	0.2	-0.1	0.2	-0.4	0.3	0.5	0.2	-0.1	0.5	0.8	0.5
Fluid intelligence score	0.1	0.2	1.9	-1.4	0.1	-0.3	0.0	-0.3	-0.3	-0.3	-0.4	-0.3	0.7	0.4	-0.1	0.1	-0.1	-0.2
Noisy workplace	0.1	0.1	0.5	0.3	-0.6	0.1	0.1	0.0	-0.2	0.5	0.3	0.6	-0.1	0.7	0.3	0.2	-0.2	0.4
Chest pain or discomfort	0.1	0.1	0.4	0.5	-0.2	-0.5	0.5	-0.3	-0.4	0.2	-0.3	0.3	-0.7	0.1	-0.2	0.5	-0.1	0.0
Hypertension (Self-reported)	0.1	0.2	0.6	-0.2	0.4	0.4	-0.6	0.3	0.2	-0.1	0.4	-0.8	-0.1	-0.0	-0.1	-0.5	-0.4	-0.7
Medication: Blood pressure	0.1	0.1	0.7	0.5	0.5	0.2	0.4	0.8	0.7	0.4	-0.1	-0.0	0.2	0.2	-0.0	0.1	0.4	0.0
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.8	0.9	0.2	0.5	-0.2	0.2	0.0	0.1	0.2	-0.4	-0.4	-0.0	-0.8	-0.2	-0.2	-0.3
Vascular/heart problems diagnosed by doctor	0.1	0.3	0.9	-0.3	-0.2	-0.3	0.8	-0.2	-0.3	0.3	-0.7	0.9	0.3	0.2	0.2	0.8	0.8	0.9
Cholesterol lowering medication	0.1	0.2	0.9	-0.1	-0.1	0.4	0.2	0.4	-0.6	0.4	-0.0	0.2	1.0	0.6	-0.2	0.1	0.1	0.3
Hair Pigment	0.0	0.8	4.5	0.8	0.7	-1.0	0.5	-0.3	-0.1	-0.2	-1.7	0.4	0.3	-0.7	-1.0	1.0	2.1	-0.1
Hayfever, allergic rhinitis or eczema	0.0	0.1	0.4	0.4	-0.2	-0.6	0.2	-0.3	0.4	-0.1	-0.1	0.1	-0.6	-0.2	0.3	-0.0	-0.3	-0.1

Hub : Genes

TOX4

Models

Trait associations