[Hub]/) : Traits : Sitting height :

chr16:19,937,475-21,352,507

Best TWAS P=1.62e-12 · Best GWAS P=2.62e-12 conditioned to 0.19

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex THUMPD1 0.05 0.01 bslmm 403 0.02 3.2e-03 -6.59 5.5 2.8e-08 -0.73 0.02 0.87 FALSE
2 GTEx Adipose Subcutaneous AC004381.6 0.09 0.04 enet 35 0.02 1.6e-02 -4.75 -5.9 3.3e-09 0.48 0.20 0.43 FALSE
3 GTEx Adipose Subcutaneous ERI2 0.06 0.02 enet 3 0.01 3.3e-02 -6.76 -6.6 3.4e-11 0.87 0.03 0.91 FALSE
4 GTEx Brain Cerebellum AC004381.6 0.23 0.09 enet 18 0.12 1.9e-04 -4.75 -5.2 2.6e-07 0.50 0.23 0.22 FALSE
5 GTEx Cells Transformed fibroblasts THUMPD1 0.13 0.16 enet 16 0.16 4.2e-12 -6.77 -7.1 1.6e-12 0.92 0.02 0.98 TRUE
6 GTEx Testis AC004381.6 0.18 0.10 lasso 7 0.08 1.8e-04 -6.80 -6.9 6.4e-12 0.93 0.02 0.95 FALSE
7 METSIM Adipose ACSM1 0.05 0.05 lasso 5 0.06 9.5e-09 -6.72 -6.4 2.0e-10 0.87 0.03 0.97 FALSE
8 METSIM Adipose THUMPD1 0.03 0.00 blup 382 0.02 4.9e-04 -0.26 -5.3 1.4e-07 0.68 0.06 0.89 FALSE
9 ROSMAP Brain Pre-frontal Cortex THUMPD1 0.08 0.12 enet 24 0.12 3.0e-15 -6.72 6.6 4.7e-11 -0.93 0.02 0.98 FALSE
10 ROSMAP Brain Pre-frontal Cortex ACSM1 0.07 0.06 lasso 8 0.06 1.0e-07 -4.90 -5.7 1.5e-08 0.58 0.90 0.10 FALSE
11 YFS Blood THUMPD1 0.03 0.03 lasso 14 0.03 5.4e-10 -4.74 -6.0 1.6e-09 0.66 0.58 0.42 FALSE
12 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma THUMPD1 0.04 0.04 blup 30 0.03 2.3e-03 -6.78 -7.0 1.7e-12 0.92 0.01 0.86 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma ACSM3 0.06 0.06 lasso 13 0.05 2.8e-06 -6.77 6.8 1.3e-11 -0.94 0.01 0.99 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma THUMPD1 0.07 0.06 blup 30 0.06 5.6e-07 -6.77 5.7 1.2e-08 -0.86 0.01 0.99 FALSE
15 The Cancer Genome Atlas Soft Tissue Sarcoma ACSM1 0.10 0.05 blup 54 0.07 7.8e-05 -6.77 -5.6 1.7e-08 0.74 0.00 0.98 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma ACSM3 0.06 0.04 blup 43 0.03 5.9e-04 -6.81 6.8 1.2e-11 -0.90 0.01 0.96 FALSE