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chr17:923,916-2,420,934

Best TWAS P=3.49e-11 · Best GWAS P=4.61e-10 conditioned to 0.297

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	SERPINF1	0.19	0.05	lasso	6	0.02	6.3e-03	5.6	-5.2	2.0e-07	0.57	0.06	0.71	FALSE
2	GTEx	Adipose Subcutaneous	SMYD4	0.20	0.14	lasso	2	0.16	2.6e-13	5.8	-5.9	2.8e-09	0.55	0.03	0.97	FALSE
3	GTEx	Artery Tibial	SMYD4	0.20	0.18	enet	10	0.18	8.2e-14	5.5	-5.5	3.8e-08	0.53	0.07	0.93	FALSE
4	GTEx	Brain Cortex	SMYD4	0.34	0.17	lasso	4	0.23	5.3e-07	5.8	-6.6	4.9e-11	0.51	0.02	0.92	FALSE
5	GTEx	Cells Transformed fibroblasts	SERPINF1	0.20	0.11	lasso	3	0.16	5.6e-12	5.6	-6.6	3.5e-11	0.86	0.01	0.99	TRUE
6	GTEx	Colon Sigmoid	SMYD4	0.33	0.24	lasso	7	0.24	5.0e-09	5.5	-5.8	4.8e-09	0.55	0.04	0.96	FALSE
7	GTEx	Esophagus Muscularis	SMYD4	0.24	0.16	lasso	3	0.18	3.1e-11	5.6	-5.6	1.8e-08	0.54	0.06	0.94	FALSE
8	GTEx	Lung	SMYD4	0.10	0.09	lasso	3	0.09	1.4e-07	5.5	-5.7	1.2e-08	0.55	0.04	0.96	FALSE
9	GTEx	Nerve Tibial	SMYD4	0.23	0.14	lasso	4	0.17	3.2e-12	5.8	-5.8	5.7e-09	0.56	0.02	0.98	FALSE
10	GTEx	Skin Not Sun Exposed Suprapubic	SMYD4	0.28	0.06	enet	36	0.12	5.8e-07	5.8	-5.7	9.7e-09	0.67	0.01	0.98	FALSE
11	GTEx	Testis	SERPINF1	0.29	0.14	lasso	6	0.13	3.0e-06	-5.8	-5.2	1.5e-07	0.93	0.01	0.97	FALSE
12	GTEx	Testis	SMYD4	0.24	0.09	enet	14	0.10	2.9e-05	5.9	-6.1	1.0e-09	0.55	0.02	0.96	FALSE
13	GTEx	Thyroid	SMYD4	0.32	0.13	enet	11	0.23	1.5e-17	5.8	-6.6	3.9e-11	0.81	0.03	0.97	FALSE
14	YFS	Blood	SMYD4	0.17	0.15	bslmm	436	0.18	1.2e-55	5.6	-5.5	5.1e-08	0.68	0.10	0.90	FALSE
15	YFS	Blood	WDR81	0.17	0.16	enet	22	0.18	1.3e-57	5.6	5.2	2.0e-07	-0.77	0.06	0.94	FALSE
16	The Cancer Genome Atlas	Glioblastoma Multiforme	SMYD4	0.20	0.10	lasso	6	0.20	1.3e-06	5.8	-6.4	2.1e-10	0.47	0.02	0.88	FALSE
17	The Cancer Genome Atlas	Prostate Adenocarcinoma	SERPINF1	0.06	0.03	blup	68	0.05	8.8e-06	5.8	-5.2	1.9e-07	0.75	0.02	0.97	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	SMYD4	0.08	0.09	lasso	9	0.08	6.3e-09	5.3	-5.4	5.7e-08	0.50	0.04	0.96	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	SMYD4	0.08	0.09	lasso	3	0.07	3.5e-07	5.8	-5.7	1.1e-08	0.52	0.01	0.99	FALSE