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chr16:86,667,409-90,172,696

Best TWAS P=1.16e-10 · Best GWAS P=6.68e-14 conditioned to 0

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adrenal Gland	URAHP	0.22	0.04	enet	16	0.17	8.2e-07	-4.64	-5.5	4.3e-08	-0.04	0.09	0.21	TRUE
2	GTEx	Artery Tibial	CHMP1A	0.21	0.06	enet	34	0.11	7.3e-09	2.62	5.8	6.5e-09	0.03	0.11	0.04	FALSE
3	GTEx	Brain Cortex	GAS8	0.28	0.16	lasso	6	0.14	1.3e-04	-4.64	-5.2	1.9e-07	-0.01	0.14	0.49	FALSE
4	GTEx	Brain Cortex	URAHP	0.34	0.19	enet	15	0.17	2.4e-05	-4.64	-6.0	2.0e-09	-0.02	0.13	0.68	FALSE
5	GTEx	Cells Transformed fibroblasts	RPL13	0.10	0.08	enet	8	0.09	3.7e-07	4.36	-5.5	4.6e-08	-0.03	0.02	0.98	FALSE
6	GTEx	Colon Transverse	DBNDD1	0.62	0.40	enet	40	0.44	1.2e-22	-4.64	-5.3	1.0e-07	0.06	0.14	0.84	TRUE
7	GTEx	Colon Transverse	RPL13	0.23	0.17	lasso	4	0.16	3.7e-08	5.34	-5.9	2.8e-09	-0.03	0.01	0.99	TRUE
8	GTEx	Esophagus Muscularis	CHMP1A	0.15	0.01	enet	32	0.09	6.6e-06	-2.85	5.2	1.5e-07	0.05	0.06	0.20	TRUE
9	GTEx	Esophagus Muscularis	RPL13	0.17	0.12	lasso	3	0.11	2.4e-07	5.34	-5.4	7.3e-08	-0.05	0.01	0.99	TRUE
10	GTEx	Liver	ACSF3	0.56	0.14	lasso	16	0.10	1.2e-03	3.39	5.6	1.8e-08	-0.03	0.50	0.03	FALSE
11	GTEx	Lung	RP5-1142A6.5	0.15	0.08	lasso	3	0.09	4.0e-07	-5.92	-5.1	3.0e-07	0.24	0.93	0.02	FALSE
12	GTEx	Nerve Tibial	CHMP1A	0.34	0.06	enet	60	0.12	1.6e-08	0.47	5.6	2.6e-08	0.04	0.07	0.05	TRUE
13	GTEx	Skin Not Sun Exposed Suprapubic	RPL13	0.16	0.15	lasso	4	0.15	2.0e-08	5.25	-5.2	1.9e-07	-0.03	0.01	0.99	TRUE
14	GTEx	Skin Sun Exposed Lower leg	FBXO31	0.08	0.09	lasso	5	0.08	4.0e-07	-5.69	-5.3	1.2e-07	0.04	0.00	1.00	FALSE
15	GTEx	Thyroid	RPL13	0.13	0.05	enet	10	0.06	1.4e-05	5.35	-5.6	1.7e-08	-0.04	0.01	0.98	FALSE
16	GTEx	Uterus	SNAI3-AS1	0.47	0.00	enet	13	0.04	5.3e-02	-3.98	5.5	2.8e-08	-0.37	0.05	0.09	FALSE
17	GTEx	Whole Blood	SPG7	0.06	0.05	lasso	3	0.05	3.9e-05	5.30	-5.5	4.8e-08	-0.04	0.02	0.97	FALSE
18	GTEx	Whole Blood	SNAI3-AS1	0.15	0.04	enet	21	0.10	6.7e-10	0.41	5.8	6.1e-09	-0.39	0.79	0.15	FALSE
19	GTEx	Whole Blood	CTD-2555A7.3	0.10	0.00	lasso	5	0.01	1.0e-01	3.42	5.6	2.7e-08	-0.12	0.07	0.53	FALSE
20	METSIM	Adipose	APRT	0.06	0.04	lasso	5	0.02	7.4e-04	-5.56	5.9	4.5e-09	-0.18	0.61	0.02	TRUE
21	METSIM	Adipose	MAP1LC3B	0.09	0.07	enet	11	0.06	2.1e-09	-5.43	5.4	6.2e-08	-0.02	0.01	0.99	TRUE
22	METSIM	Adipose	RPL13	0.05	0.05	enet	5	0.05	1.0e-07	5.35	-5.2	2.7e-07	-0.04	0.01	0.99	FALSE
23	The Cancer Genome Atlas	Esophageal Carcinoma	RPL13	0.14	0.07	lasso	3	0.04	2.6e-02	5.13	-5.2	2.0e-07	-0.04	0.01	0.82	FALSE
24	The Cancer Genome Atlas	Glioblastoma Multiforme	SNAI3	0.19	0.06	enet	7	0.12	1.6e-04	3.23	-6.4	1.2e-10	0.26	0.00	0.86	TRUE
25	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CBFA2T3	0.04	0.04	lasso	3	0.03	1.2e-04	-5.84	6.0	2.0e-09	-0.22	0.00	1.00	TRUE
26	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SPG7	0.05	0.05	lasso	5	0.05	1.9e-06	5.13	-5.2	2.4e-07	-0.03	0.01	0.99	FALSE
27	The Cancer Genome Atlas	Brain Lower Grade Glioma	MGC23284	0.09	0.04	enet	19	0.03	1.7e-04	-4.15	-6.0	2.2e-09	0.30	0.09	0.86	FALSE
28	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RPL13	0.03	0.01	blup	41	0.02	8.5e-03	5.26	-5.4	8.2e-08	-0.03	0.01	0.77	FALSE
29	The Cancer Genome Atlas	Rectum Adenocarcinoma	FBXO31	0.37	-0.01	blup	78	-0.01	4.5e-01	-0.88	-5.3	1.0e-07	0.04	0.01	0.24	FALSE
30	The Cancer Genome Atlas	Stomach Adenocarcinoma	RPL13	0.04	0.03	blup	41	0.03	2.2e-03	4.47	-5.4	6.1e-08	-0.04	0.01	0.86	FALSE
31	The Cancer Genome Atlas	Thyroid Carcinoma	DBNDD1	0.17	0.00	blup	66	0.04	6.6e-05	-3.91	-6.1	1.3e-09	0.05	0.00	0.04	TRUE