Best TWAS P=4.08e-11 · Best GWAS P=7.7e-12 conditioned to 0.0549
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | ZNF788 | 0.08 | 0.05 | lasso | 6 | 0.04 | 5.9e-06 | 6.6 | 6.6 | 4.1e-11 | 0.93 | 0.01 | 0.99 | TRUE |
2 | GTEx | Testis | ZNF442 | 0.16 | 0.06 | enet | 3 | 0.02 | 4.4e-02 | 4.3 | 5.1 | 2.6e-07 | 0.34 | 0.05 | 0.54 | FALSE |
3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ZNF844 | 0.02 | 0.01 | blup | 27 | 0.01 | 9.2e-03 | 5.7 | -5.5 | 3.0e-08 | -0.68 | 0.02 | 0.23 | FALSE |