TWAS hub - ZNF788

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0830	0.0270	1.5e-05	0.049	0.029	0.038	0.030	0.043	1.1e-06	0.00018	1.7e-05	0.00012	5.9e-06
2	YFS	Blood	0.0159	0.0087	1.3e-02	-0.001	0.004	0.000	0.004	0.000	6.8e-01	0.01600	3.2e-01	0.01200	4.0e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Stomach or abdominal pain in last month	7.1	8.8	15.3	-1.6	-3.9
High blood pressure (mother)	5.0	7.0	12.6	1.1	3.5
Illnesses of father: None of the above (group 1)	5.0	6.2	10.5	-1.4	-3.2
Serious illness, injury or assault of a close relative in last 2 years	4.7	5.4	6.4	-2.5	-2.1
Commuting to job workplace: Car/motor vehicle	4.5	5.2	10.2	0.5	3.2
Standing height	4.4	44.0	87.2	9.3	0.9
Primary Biliary Cirrhosis	4.2	6.0	8.1	2.8	2.0
Height	3.6	68.9	136.9	11.7	0.9
Mineral and other dietary supplements	3.5	4.7	6.8	-1.7	-2.6
Sitting height	3.3	23.4	43.6	6.6	1.8
Type 2 Diabetes (T2D) (2012)	3.1	3.5	6.5	2.5	0.8
Hearing difficulty/problems: Yes	3.0	4.5	5.7	-1.8	-2.4
Illnesses of mother	3.0	3.8	7.4	-0.4	-2.7
Medication: Lisinopril	3.0	3.9	4.8	1.7	2.2
Medication: Blood pressure	2.9	5.0	9.7	-0.6	3.1
Supplements: Fish oil (including cod liver oil)	2.9	3.7	5.2	1.5	2.3
Medication: Seretide 50 evohaler	2.8	3.2	6.2	-0.3	-2.5
Comparative height size at age 10	2.8	15.5	30.6	5.5	0.7
Trunk fat-free mass	2.7	15.4	30.6	5.5	0.4
Trunk predicted mass	2.7	15.4	30.5	5.5	0.5
Medication for cholesterol, blood pressure or diabetes	2.7	4.4	8.9	-0.0	-3.0
Wears glasses or contact lenses	2.6	3.0	6.0	0.1	2.5
Leg pain on walking	2.5	3.1	4.9	-1.1	-2.2
Eye problems/disorders: Cataract	2.5	2.8	3.3	1.5	1.8
Medication: Aspirin	2.5	3.2	6.4	0.3	2.5
Average weekly spirits intake	2.4	3.0	5.6	-0.7	-2.4
High blood pressure	2.2	6.1	9.7	-1.6	3.1
Depression (self-reported)	2.2	2.6	4.8	-2.2	-0.6
Commuting to job workplace: Cycle	2.2	2.6	4.5	-2.1	-0.9
Hypertension (Self-reported)	2.1	5.8	9.0	-1.6	3.0
Whole body fat-free mass	2.1	12.1	24.2	4.9	0.0
Whole body water mass	2.1	11.8	23.6	4.9	-0.0
Vascular/heart problems diagnosed by doctor	2.1	5.7	8.7	1.6	-3.0
Bipolar Disorder or Schizophrenia	2.0	4.8	9.4	-3.1	-0.4
Medication: Levothyroxine sodium	2.0	3.4	6.5	0.6	2.5
Health satisfaction	2.0	2.6	2.9	-1.7	-1.5
Average weekly champagne plus white wine intake	1.9	2.7	4.8	-0.7	-2.2
Arm predicted mass (left)	1.9	9.6	19.3	4.4	-0.0
Medication: Aspirin	1.8	2.4	4.7	-0.1	2.2
Schizophrenia (2018)	1.7	3.5	7.0	-2.6	0.0
Medication: Atenolol	1.7	2.1	3.8	-2.0	-0.6
Qualifications: O levels/GCSEs or equivalent	1.7	2.7	5.3	-2.3	-0.1
Basal metabolic rate	1.7	9.7	19.2	4.4	-0.4
Arm fat-free mass (left)	1.7	8.4	16.6	4.1	-0.4
Basal cell carcinoma (self-reported)	1.7	2.0	4.0	2.0	-0.1
Rheumatoid Arthritis	1.6	2.2	4.3	-2.1	-0.3
Leg predicted mass (left)	1.6	8.2	15.7	4.0	-0.9
Pain all over the body in last month	1.6	1.7	2.9	-0.7	-1.7
Falls in the last year	1.6	2.1	3.4	-0.9	-1.9
Arm fat-free mass (right)	1.6	8.3	16.6	4.1	0.0
Neck or shoulder pain in last month	1.6	2.3	2.3	-1.5	-1.5
Arm predicted mass (right)	1.6	8.4	16.8	4.1	-0.3
Unable to work because of sickness or disability	1.6	2.1	2.2	-1.5	-1.4
Angina	1.5	2.0	3.4	-1.8	-0.8
Leg fat-free mass (left)	1.5	7.8	14.9	3.9	-0.9
Hypothyroidism/myxoedema (self-reported)	1.5	2.9	5.1	0.9	2.3
Forced expiratory volume in 1-second (FEV1), predicted	1.5	3.2	4.7	2.2	1.3
Age at First Birth	1.4	2.0	2.4	-1.3	1.5
Cardiovascular Disease	1.4	4.6	8.3	-1.0	2.9
Illnesses of father: Heart disease	1.4	1.9	3.2	0.8	1.8
Leg fat-free mass (right)	1.4	7.2	14.3	3.8	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.7	3.2	-0.4	-1.8
Leg predicted mass (right)	1.4	7.4	14.6	3.8	-0.3
Type 2 Diabetes (T2D) (2018)	1.3	2.4	4.7	2.2	0.3
Medication: Co-codamol	1.3	1.5	2.1	-1.5	-1.0
Heart attack	1.3	1.7	2.2	-1.1	1.5
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	1.8	1.2	1.3
Smoking status: Current	1.3	2.0	2.7	-1.2	-1.6
Financial situation satisfaction	1.3	1.6	3.1	-0.4	-1.8
High cholesterol (Self-reported)	1.3	2.3	4.2	-2.0	-0.7
Ovarian Cancer	1.2	1.5	3.0	-1.7	-0.3
Medication for hormone replacement therapy	1.2	1.3	2.6	-1.6	-0.3
Severe depression (siblings)	1.2	1.3	1.8	1.4	0.9
Chronic bronchitis/emphysema (father)	1.2	1.4	2.0	1.4	0.9
Noisy workplace	1.2	1.4	2.7	-1.6	-0.4
Blood clot in the leg (DVT)	1.2	1.5	2.9	1.7	0.3
Comparative body size at age 10	1.2	3.3	3.9	-1.6	-2.0
Ever had prostate specific antigen (PSA) test	1.2	1.4	2.1	1.5	0.8
Heart attack/myocardial infarction (self-reported)	1.2	1.5	2.4	-0.8	1.5
Alcohol drinker status: Previous	1.2	1.3	2.1	-1.5	-0.7
Alzheimer’s Disease (in father)	1.1	1.2	1.3	-1.1	1.0
Prostate Cancer	1.1	1.5	2.6	-0.7	-1.6
Mean Putamen Volume	1.1	1.2	2.0	0.7	1.4
Schizophrenia (2014)	1.1	2.4	4.8	-2.2	-0.1
Ulcerative Colitis	1.1	1.7	2.7	1.7	-0.8
Hypothyroidism (self reported)	1.1	2.4	3.5	1.2	1.9
Chronotype (morning person)	1.1	2.6	3.1	1.5	1.8
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.7	2.6	-1.6	-0.9
Medication: Lansoprazole	1.1	1.3	1.5	-1.0	-1.2
Angina (self-reported)	1.1	1.4	2.6	-1.6	-0.5
Number of full sisters	1.1	1.4	2.4	0.6	1.6
Commuting to job workplace: Walk	1.1	1.2	2.3	-0.3	-1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.4	4.5	-2.1	-0.6
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	2.7	1.6	0.2
Bipolar Disorder (2018)	1.0	1.6	2.6	-1.6	-0.7
Blood Red Count	1.0	9.9	10.8	-3.3	-3.0
Frequency of depressed mood in last 2 weeks	1.0	1.4	2.0	-1.4	-0.8
Hearing difficulty/problems with background noise	1.0	1.6	1.6	-1.3	-1.2
Diabetes (self-reported)	1.0	1.6	3.2	1.8	0.1
Weight	1.0	4.9	8.1	2.9	-1.3
Pulse rate	1.0	1.6	2.3	1.5	1.0
Medication: Cholesterol lowering	1.0	1.5	2.0	-1.0	1.4
Loud music exposure frequency	1.0	1.1	2.0	-0.4	-1.4
Medication: Paracetamol	1.0	1.6	3.1	-0.4	1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	1.3	1.0	1.1
Osteoporosis (self-reported)	1.0	1.3	1.3	-1.1	-1.1
Intelligence (Savage-Jansen 2018)	0.9	2.7	3.9	-1.2	2.0
Ulcerative Colitis (UC)	0.9	1.8	3.0	1.7	-0.8
Current tobacco smoking	0.9	1.4	2.4	-0.7	-1.5
Average weekly fortified wine intake	0.9	1.1	1.2	0.9	-1.1
Number of incorrect matches in round	0.9	1.6	3.1	-0.2	1.8
Alcohol usually taken with meals	0.9	1.5	2.1	1.4	-0.9
Father’s age at death	0.9	1.2	2.0	0.5	-1.4
Pulse wave Arterial Stiffness index	0.9	1.0	1.9	1.4	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	1.7	-1.3	-0.7
Friendships satisfaction	0.9	1.1	1.4	-0.9	-1.2
Illnesses of father: High blood pressure	0.9	1.1	1.7	-0.6	1.3
Fasting Glucose	0.8	1.0	1.6	1.3	0.6
Smoking Status	0.8	2.0	2.1	-1.4	-1.4
Number of treatments/medications taken	0.8	1.5	2.9	-0.0	1.7
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	1.5	0.6	-1.2
Hand grip strength (right)	0.8	2.1	2.2	1.5	-1.4
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	1.6	0.7	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	1.1	-1.0	-1.1
Birth weight of first child	0.8	1.4	1.4	1.1	1.2
Migraine (self-reported)	0.8	1.0	1.7	1.3	0.6
Had major operations	0.8	0.9	1.1	-1.1	-0.8
Arm fat percentage (left)	0.8	3.2	3.5	-1.7	-1.9
Qualifications: nursing, teaching	0.8	1.2	2.4	-1.5	-0.1
Breast cancer (self-reported)	0.8	0.9	1.4	-1.2	0.7
Bipolar Disorder (2011)	0.7	0.7	1.0	-1.0	-0.6
LDL Cholesterol	0.7	1.2	2.0	-1.4	-0.6
Heel T-Score	0.7	5.8	10.2	-3.2	-1.2
Lung FVC	0.7	3.5	6.5	-2.5	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	1.8	-1.4	0.2
Bilateral oophorectomy (both ovaries removed)	0.7	0.9	1.1	1.1	-0.8
Supplements: Glucosamine	0.7	0.9	1.7	0.4	1.3
Nervous feelings	0.7	1.3	1.4	-1.2	-1.1
Had other major operations	0.7	0.9	1.5	1.2	0.4
Medication: Simvastatin	0.7	1.1	2.0	-1.4	0.4
Time employed in main current job	0.7	0.8	1.4	-0.5	1.2
Gout (self-reported)	0.7	1.0	2.0	1.4	-0.1
Leg fat percentage (right)	0.7	2.7	3.7	-1.3	-1.9
Medication: Ibuprofen	0.7	0.9	1.6	-0.4	-1.3
Medication: Allopurinol	0.7	1.0	1.7	1.3	0.5
Illnesses of siblings: Diabetes	0.7	0.8	1.3	-0.6	-1.1
Loneliness, isolation	0.7	0.9	1.1	-1.1	-0.8
Osteoarthritis (self-reported)	0.7	0.9	1.6	1.2	0.5
Commuting to job workplace: Public transport	0.7	0.8	1.6	-0.0	-1.2
Alcohol drinker status: Never	0.7	0.8	1.7	1.3	0.2
Cholesterol lowering medication	0.7	1.1	1.2	-1.1	-0.9
Breast Cancer	0.6	1.5	2.3	-0.8	-1.5
Waist Hip Ratio (WHR)	0.6	2.9	5.6	2.4	0.4
Respiratory disease	0.6	1.4	2.5	0.4	-1.6
Hand grip strength (left)	0.6	1.5	2.0	1.4	-1.0
Townsend deprivation index at recruitment	0.6	0.8	1.5	-0.2	-1.2
Maternal smoking around birth	0.6	0.9	1.1	0.8	1.1
Body mass index (BMI)	0.6	2.4	3.2	-1.3	-1.8
Trunk fat mass	0.6	2.5	2.8	1.5	-1.7
Illnesses of siblings	0.6	0.9	1.2	1.1	0.7
Lung cancer (father)	0.6	0.7	1.0	-1.0	-0.6
Exposure to tobacco smoke at home	0.6	0.6	0.8	-0.9	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	1.6	-1.3	0.3
Glaucoma (self-reported)	0.6	0.7	1.3	-1.1	-0.1
Forced vital capacity (FVC), Best measure	0.6	2.3	4.5	2.1	0.2
Mean time to correctly identify matches	0.6	1.1	2.1	-1.4	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	1.2	-1.1	-0.4
Knee pain experienced in last month	0.6	0.9	1.8	0.1	-1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.3	-0.4	-1.1
Handedness (chirality/laterality): Left-handed	0.6	0.7	1.2	1.1	0.5
Ever had bowel cancer screening	0.6	0.8	1.3	1.2	0.4
Leg fat percentage (left)	0.6	2.1	2.3	-1.5	-1.4
Pain experienced in last month	0.6	0.9	1.8	0.2	1.3
Alzheimer’s Disease (including proxy)	0.5	0.7	1.4	-1.2	-0.2
Crohns Disease (2017)	0.5	1.1	1.9	-1.4	-0.5
Reaction Time	0.5	1.0	1.7	-1.3	-0.5
Lupus	0.5	0.7	1.5	1.2	0.1
Systolic Blood Pressure	0.5	2.4	4.1	0.8	2.0
Lung FEV1/FVC ratio	0.5	2.3	2.9	-1.7	1.3
Sensitivity / hurt feelings	0.5	0.8	1.6	1.3	-0.1
Relative age of first facial hair	0.5	1.0	1.2	0.9	-1.1
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.1	0.3	1.1
Trunk fat percentage	0.5	1.9	3.8	0.1	-2.0
Taking other prescription medications	0.5	0.7	1.4	-1.2	0.0
Age when periods started (menarche)	0.5	1.2	1.9	1.4	-0.7
Forced vital capacity (FVC)	0.5	2.0	3.9	2.0	-0.3
Arm fat percentage (right)	0.5	2.0	2.3	-1.3	-1.5
Hair/balding pattern: Pattern 3	0.5	0.8	1.0	-0.7	-1.0
Tense / ‘highly strung’	0.5	0.8	1.3	-1.2	-0.4
Peak expiratory flow (PEF)	0.5	1.1	1.7	0.7	-1.3
Age at first live birth	0.5	0.8	1.0	-0.8	1.0
Diabetes diagnosed by doctor	0.5	0.8	0.8	0.9	-0.8
Tinnitus: Yes, now most or all of the time	0.5	0.6	0.9	-0.6	-0.9
Ever smoked	0.5	0.9	1.6	-0.4	-1.2
Risk taking	0.5	0.7	1.5	-1.2	-0.2
Ever depressed for a whole week	0.5	0.6	1.2	-1.1	-0.1
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	0.9	0.9	-0.4
Waist circumference	0.4	1.4	1.4	1.2	-1.2
Allergy	0.4	0.8	1.6	-1.3	0.1
Arm fat mass (right)	0.4	1.6	3.3	-0.1	-1.8
Pulse wave reflection index	0.4	0.6	0.8	0.9	-0.6
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	0.9	-0.2	-0.9
Birth weight	0.4	0.9	1.3	-1.1	-0.7
Body fat percentage	0.4	1.6	2.9	-0.6	-1.7
Pulse wave peak to peak time	0.4	0.5	0.8	-0.9	0.4
Medication for pain relief, constipation, heartburn	0.4	0.7	1.3	0.3	-1.1
Whole body fat mass	0.4	1.6	2.2	1.0	-1.5
Leg fat mass (right)	0.4	1.6	3.1	0.2	-1.8
Medication for cholesterol	0.4	0.7	1.1	1.0	0.5
Asthma (self-reported)	0.4	0.9	1.1	1.1	-0.8
Arm fat mass (left)	0.4	1.7	3.4	0.1	-1.8
Medication: Bendroflumethiazide	0.4	0.7	1.1	-0.5	1.0
Irritability	0.4	0.6	1.1	-1.1	0.2
Fractured/broken bones in last 5 years	0.4	0.6	0.6	0.7	-0.8
Age started oral contraceptive pill	0.4	0.5	0.6	0.6	0.8
Pack years of smoking	0.4	0.6	1.1	1.1	0.0
Depression (Nagel 2018)	0.3	0.4	0.8	-0.9	-0.1
HDL Cholesterol	0.3	0.5	0.9	0.2	-1.0
Neuroticism (2016)	0.3	0.4	0.8	-0.9	-0.1
Systolic blood pressure, automated reading	0.3	1.0	1.3	0.8	1.1
Medication: Metformin	0.3	0.4	0.7	0.1	-0.9
Pack years adult smoking proportion	0.3	0.4	0.7	0.8	-0.4
Had menopause	0.3	0.3	0.5	0.5	0.7
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	0.6	-0.8	0.2
Mouth/teeth dental problems	0.3	0.5	0.5	0.6	0.7
Hip circumference	0.3	1.5	2.2	1.5	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.0	-1.0	-0.1
Happiness	0.3	0.3	0.3	0.6	-0.6
Asthma	0.3	0.6	0.9	1.0	-0.6
Medication: Ventolin 100micrograms inhaler	0.3	0.4	0.8	-0.0	-0.9
Worry too long after embarrassment	0.3	0.5	0.9	0.2	0.9
Heart disease (mother)	0.3	0.4	0.7	-0.3	0.8
Alcohol intake frequency.	0.3	0.7	1.5	0.0	-1.2
Supplements: Vitamin C	0.3	0.4	0.5	0.5	-0.7
Smoking status: Previous	0.3	0.5	0.9	0.2	1.0
Number of self-reported non-cancer illnesses	0.3	0.6	1.1	-0.1	1.1
Ever taken oral contraceptive pill	0.3	0.4	0.5	0.5	0.7
Mother’s age at death	0.3	0.4	0.7	-0.4	-0.8
Diastolic blood pressure, automated reading	0.3	1.0	1.9	0.3	1.4
Leg fat mass (left)	0.3	1.1	2.1	0.1	-1.4
Depressed Affect (Nagel 2018)	0.2	0.4	0.7	0.8	-0.4
Schizophrenia vs Biploar Disorder	0.2	0.3	0.5	0.3	0.7
Irritable Bowel Disease (IBD)	0.2	0.5	0.9	0.1	-1.0
Major Depression (MDD)	0.2	0.2	0.3	-0.3	-0.6
Coronary Artery Disease (CAD)	0.2	0.3	0.5	-0.1	-0.7
Tanning	0.2	3.1	3.9	1.5	2.0
Ever had hysterectomy (womb removed)	0.2	0.2	0.4	-0.3	-0.6
Diabetes (mother)	0.2	0.2	0.3	0.3	0.5
Relative age voice broke	0.2	0.4	0.6	0.8	0.4
Qualifications: CSEs or equivalent	0.2	0.2	0.4	-0.6	-0.1
Multivitamins +/- minerals	0.2	0.3	0.6	0.0	0.8
Hair/balding pattern: Pattern 2	0.2	0.2	0.3	-0.5	0.4
Qualifications: None of the above	0.2	0.5	1.0	1.0	0.1
Medication: Ramipril	0.2	0.3	0.4	-0.4	0.6
Fluid intelligence score	0.2	0.4	0.4	-0.7	-0.5
Worrier / anxious feelings	0.2	0.3	0.4	-0.5	-0.6
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	1.3	1.2	-0.5
Prospective memory result	0.2	0.3	0.4	0.4	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	1.1	1.0	-0.4
Breastfed as a baby	0.2	0.2	0.4	0.1	0.7
Medication: Amlodipine	0.2	0.3	0.6	0.2	0.8
High blood pressure (siblings)	0.2	0.3	0.3	0.4	0.6
Exposure to tobacco smoke outside home	0.2	0.3	0.7	-0.8	0.1
Number of full brothers	0.2	0.2	0.4	0.4	-0.6
Number of children fathered	0.2	0.2	0.3	-0.4	0.6
Emphysema/chronic bronchitis	0.2	0.3	0.3	-0.6	-0.4
Family relationship satisfaction	0.2	0.2	0.4	-0.6	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	0.4	-0.3	-0.6
Guilty feelings	0.2	0.3	0.5	0.7	-0.3
Medication: Paracetamol	0.2	0.3	0.5	0.0	0.7
Supplements: Calcium	0.2	0.2	0.4	-0.0	0.7
Worry (Nagel 2018)	0.1	0.2	0.3	-0.5	-0.4
Alzheimer’s Disease (in mother)	0.1	0.1	0.3	-0.5	0.1
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.3	-0.6	0.3
Body Mass Index (BMI) (2010)	0.1	0.2	0.3	-0.2	0.5
HbA1C	0.1	0.2	0.2	0.4	0.3
Blood Eosinophil Count	0.1	0.5	0.9	-0.9	0.4
Blood Platelet Count	0.1	1.5	3.0	1.7	-0.3
Blood White Count	0.1	1.0	1.2	-0.9	-1.1
BMI	0.1	0.4	0.4	-0.6	-0.7
Allergy or Eczema	0.1	0.3	0.5	-0.3	-0.7
Neuroticism	0.1	0.2	0.3	-0.5	0.3
Supplements: Zinc	0.1	0.1	0.1	-0.1	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.3	-0.6	-0.4
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.2	-0.1	0.4
Serious illness, injury or assault to yourself	0.1	0.2	0.3	-0.5	0.1
Hayfever, allergic rhinitis or eczema	0.1	0.3	0.3	0.5	-0.6
Impedance of leg (left)	0.1	0.4	0.7	0.2	0.8
Financial difficulties in last 2 years	0.1	0.2	0.2	-0.4	-0.4
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.1	0.3	0.3
Neuroticism score	0.1	0.1	0.3	-0.1	-0.5
Alcohol intake versus 10 years previously	0.1	0.2	0.2	-0.4	-0.5
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.3	-0.4	0.6
Headache pain in last month	0.1	0.1	0.3	-0.5	-0.1
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.3	-0.0	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.2	-0.3	0.4
Wheeze or whistling in the chest in last year	0.1	0.2	0.2	-0.5	-0.4
Shortness of breath walking on level ground	0.1	0.1	0.2	-0.5	-0.2
Qualifications: College or University degree	0.1	0.5	0.8	0.4	0.9
Eye problems/disorders: None of the above	0.1	0.1	0.2	0.5	0.1
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.2	-0.2	-0.5
Pulse rate, automated reading	0.1	0.2	0.3	0.5	0.4
Suffer from ‘nerves’	0.1	0.2	0.2	-0.4	-0.4
Overall health rating	0.1	0.3	0.5	-0.7	-0.0
Chest pain or discomfort	0.1	0.2	0.3	-0.5	0.3
Age at last live birth	0.1	0.1	0.2	-0.4	0.2
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.2	0.1	0.5
Medication: Gliclazide	0.1	0.2	0.3	-0.1	0.6
Eye problems/disorders: Glaucoma	0.1	0.1	0.2	0.4	-0.4
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.2	-0.1	0.4
Medication: Atorvastatin	0.1	0.1	0.1	-0.3	-0.4
Number of operations (self-reported)	0.1	0.1	0.2	0.4	-0.1
Average weekly beer plus cider intake	0.1	0.2	0.3	-0.5	-0.3
Myopia	0.1	0.2	0.2	-0.5	-0.4
Neuroticism (Nagel 2018)	0.0	0.0	0.0	0.2	-0.1
Crohns Disease (2012)	0.0	0.0	0.0	-0.2	0.0
Triglycerides	0.0	0.1	0.1	0.2	-0.3
Hair Pigment	0.0	0.0	0.1	0.1	0.3
Vitamin and mineral supplements	0.0	0.0	0.0	-0.2	-0.2
Diabetes (father)	0.0	0.1	0.1	0.0	0.3
Impedance of leg (right)	0.0	0.2	0.3	0.5	0.3
Fed-up feelings	0.0	0.0	0.1	0.2	0.0
Past tobacco smoking	0.0	0.0	0.0	-0.0	-0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.0	0.1	0.0	-0.3
Impedance of arm (right)	0.0	0.1	0.3	0.5	0.0
Number of live births	0.0	0.0	0.0	0.1	0.0
Mouth/teeth dental problems: Dentures	0.0	0.0	0.0	-0.2	-0.1
Impedance of arm (left)	0.0	0.1	0.2	0.2	-0.4
Length of working week for main job	0.0	0.0	0.1	0.1	-0.3
Hair/balding pattern: Pattern 4	0.0	0.1	0.1	0.4	0.3
Ever highly irritable/argumentative for 2 days	0.0	0.0	0.0	0.1	-0.0
Medication: Omeprazole	0.0	0.1	0.1	-0.2	-0.3
Average weekly red wine intake	0.0	0.1	0.1	0.3	0.2
Mood swings	0.0	0.0	0.1	0.1	-0.2
Long-standing illness, disability or infirmity	0.0	0.0	0.0	-0.0	0.1
Back pain experienced in last month	0.0	0.1	0.1	0.3	-0.1
Miserableness	0.0	0.0	0.0	0.1	0.1
Hearing aid user	0.0	0.1	0.1	0.1	0.3
Medication: Blood pressure	0.0	0.0	0.0	-0.0	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.0	-0.0	-0.2
Heart disease (siblings)	0.0	0.0	0.0	-0.0	0.2
Impedance of whole body	0.0	0.1	0.1	0.2	-0.2

Hub : Genes

ZNF788

Models

Trait associations