Best TWAS P=9.44e-10 · Best GWAS P=4.05e-10 conditioned to 3.71e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | ST3GAL6-AS1 | 0.16 | 0.15 | lasso | 6 | 0.14 | 2.7e-11 | -4.8 | 5.5 | 4.2e-08 | 0.38 | 0.81 | 0.18 | FALSE |
2 | GTEx | Artery Tibial | ST3GAL6-AS1 | 0.24 | 0.09 | lasso | 7 | 0.17 | 1.6e-13 | 4.2 | 5.6 | 2.5e-08 | 0.32 | 0.87 | 0.13 | FALSE |
3 | GTEx | Breast Mammary Tissue (Male) | ST3GAL6-AS1 | 0.10 | -0.01 | lasso | 4 | -0.01 | 5.5e-01 | -4.2 | 6.1 | 9.4e-10 | 0.30 | 0.04 | 0.22 | TRUE |
4 | GTEx | Cells Transformed fibroblasts | CPOX | 0.22 | 0.03 | lasso | 7 | 0.04 | 4.7e-04 | 4.9 | 5.3 | 1.4e-07 | 0.24 | 0.26 | 0.48 | FALSE |
5 | GTEx | Esophagus Mucosa | ST3GAL6 | 0.21 | 0.14 | enet | 9 | 0.09 | 2.5e-06 | -4.8 | 6.1 | 1.2e-09 | 0.38 | 0.78 | 0.22 | FALSE |
6 | GTEx | Heart Atrial Appendage | ST3GAL6-AS1 | 0.55 | 0.38 | enet | 20 | 0.43 | 8.9e-21 | -4.8 | 5.2 | 2.0e-07 | 0.42 | 0.82 | 0.18 | FALSE |
7 | GTEx | Skin Sun Exposed Lower leg | ST3GAL6-AS1 | 0.18 | 0.15 | enet | 12 | 0.17 | 9.6e-14 | -4.8 | 5.2 | 1.7e-07 | 0.44 | 0.82 | 0.18 | FALSE |
8 | GTEx | Thyroid | ST3GAL6 | 0.07 | 0.02 | enet | 12 | 0.05 | 6.4e-05 | 5.7 | 5.8 | 6.5e-09 | 0.38 | 0.06 | 0.68 | FALSE |
9 | GTEx | Thyroid | ST3GAL6-AS1 | 0.25 | 0.22 | lasso | 5 | 0.20 | 3.8e-15 | -4.8 | 5.3 | 1.1e-07 | 0.35 | 0.82 | 0.18 | FALSE |
10 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DCBLD2 | 0.09 | 0.01 | enet | 16 | 0.04 | 9.6e-05 | 3.6 | 5.4 | 8.7e-08 | 0.69 | 0.06 | 0.73 | FALSE |