Best TWAS P=5.47e-23 · Best GWAS P=1.61e-35 conditioned to 1.34e-14
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | NUDT9 | 0.28 | 0.00 | enet | 29 | 0.19 | 1.1e-05 | 2.4 | 5.2 | 1.9e-07 | -0.30 | 0.07 | 0.07 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | IBSP | 0.05 | 0.05 | lasso | 6 | 0.07 | 1.2e-13 | -11.1 | 9.3 | 1.1e-20 | -0.79 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | IBSP | 0.09 | 0.02 | enet | 15 | 0.07 | 9.4e-05 | -3.0 | 9.0 | 2.3e-19 | -0.62 | 0.02 | 0.62 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | IBSP | 0.08 | 0.00 | blup | 77 | 0.00 | 1.6e-01 | -6.6 | 9.9 | 5.5e-23 | -0.71 | 0.02 | 0.63 | TRUE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | IBSP | 0.06 | 0.01 | blup | 78 | 0.03 | 8.2e-05 | -6.9 | 7.2 | 4.1e-13 | -0.56 | 0.02 | 0.87 | FALSE |
| 6 | The Cancer Genome Atlas | Lung Adenocarcinoma | DMP1 | 0.05 | 0.04 | enet | 4 | 0.04 | 2.1e-05 | -6.1 | 8.0 | 1.5e-15 | -0.70 | 0.32 | 0.44 | FALSE |
| 7 | The Cancer Genome Atlas | Lung Adenocarcinoma | IBSP | 0.06 | 0.01 | blup | 78 | 0.03 | 7.7e-05 | -11.1 | 9.9 | 6.3e-23 | -0.76 | 0.00 | 0.99 | FALSE |
| 8 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | IBSP | 0.03 | 0.01 | blup | 78 | 0.03 | 2.8e-04 | 5.1 | 5.6 | 2.2e-08 | -0.52 | 0.03 | 0.68 | FALSE |
| 9 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | IBSP | 0.16 | 0.05 | blup | 76 | 0.08 | 3.6e-06 | 7.3 | 6.8 | 1.0e-11 | -0.56 | 0.27 | 0.72 | FALSE |