TWAS hub - NUDT9

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellar Hemisphere	0.2780	0.1100	5.2e-03	0.004	NA	0.193	NA	0.053	2.4e-01	NA	1.1e-05	NA	1.7e-02
2	GTEx	Cells Transformed fibroblasts	0.2430	0.0610	5.4e-07	0.113	NA	0.100	NA	0.109	8.4e-09	NA	5.9e-08	NA	1.6e-08
3	GTEx	Nerve Tibial	0.1142	0.0448	1.2e-03	0.065	NA	0.078	NA	0.052	2.1e-05	NA	3.5e-06	NA	1.4e-04
4	GTEx	Pancreas	0.2140	0.0720	1.8e-03	0.051	NA	0.065	NA	0.036	3.4e-03	NA	1.0e-03	NA	1.2e-02
5	GTEx	Testis	0.1980	0.0730	2.8e-03	0.035	NA	0.042	NA	0.047	1.1e-02	NA	5.8e-03	NA	3.8e-03
6	ROSMAP	Brain Pre-frontal Cortex	0.0867	0.0297	9.1e-04	0.004	0.041	0.025	0.046	0.029	7.8e-02	5.2e-06	3.3e-04	1.3e-06	1.1e-04
7	TCGA	Colon Adenocarcinoma	0.0680	0.0400	8.2e-03	0.026	0.009	0.005	NA	0.004	1.2e-02	9.5e-02	1.5e-01	NA	1.8e-01
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0631	0.0248	1.0e-06	0.065	0.053	0.062	NA	0.065	7.5e-08	1.2e-06	1.8e-07	NA	8.9e-08
9	TCGA	Kidney Renal Papillary Cell Carcinoma	0.2060	0.0650	2.2e-07	0.030	0.145	0.112	NA	0.096	7.5e-03	1.2e-08	5.8e-07	NA	4.0e-06
10	TCGA	Brain Lower Grade Glioma	0.0352	0.0206	7.5e-03	0.006	0.010	0.007	NA	0.010	6.1e-02	2.3e-02	5.1e-02	NA	2.3e-02
11	TCGA	Lung Adenocarcinoma	0.0259	0.0138	2.2e-03	0.023	0.019	0.014	NA	0.012	9.3e-04	2.4e-03	7.9e-03	NA	1.4e-02
12	TCGA	Prostate Adenocarcinoma	0.1056	0.0378	3.1e-07	0.072	0.077	0.077	NA	0.059	5.0e-08	2.0e-08	1.8e-08	NA	8.4e-07
13	TCGA	Rectum Adenocarcinoma	0.5870	0.1540	4.6e-03	0.038	0.025	0.040	NA	0.028	4.5e-02	8.8e-02	4.1e-02	NA	7.4e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Verbal and Numeric Reasoning (VNR)	5.0	12.1	26.9	1.6	5.2	4.8	3.5	4.6	3.5	3.0	5.0	1.4	1.9	3.7	2.0	0.7
Supplements: Zinc	4.5	4.9	12.1	-0.2	2.3	0.4	3.5	2.9	2.5	1.8	2.7	1.5	2.6	1.2	1.1	2.9
Alzheimer’s Disease (in father)	4.3	4.7	10.5	2.6	3.0	2.6	1.1	1.6	1.7	2.9	2.3	1.2	0.2	3.2	2.5	0.7
Hearing difficulty/problems with background noise	4.3	6.8	15.9	1.4	1.9	0.7	3.7	2.9	1.5	3.3	2.1	3.9	4.0	1.3	2.9	1.4
Supplements: Glucosamine	3.8	5.0	9.9	3.1	3.1	1.6	2.2	2.3	0.5	2.7	2.8	2.1	1.4	2.3	2.2	1.2
Prospective memory result	3.8	4.7	10.9	-1.5	-2.8	-0.7	-1.3	-1.8	0.3	-3.3	-2.7	-1.7	-1.8	-2.7	-3.1	-2.2
Ever used hormone-replacement therapy (HRT)	3.7	4.7	10.8	1.7	2.2	0.9	1.4	2.2	1.6	3.3	2.4	2.1	2.6	1.7	3.1	1.3
Triglycerides	3.2	5.2	10.5	-2.0	-3.2	-3.2	-2.6	-2.7	-1.4	-2.2	-2.9	-1.5	-1.7	-2.3	-1.6	-0.2
Number of operations (self-reported)	3.1	4.5	11.3	2.8	1.7	0.2	1.2	1.4	-0.0	3.1	2.0	2.1	2.6	1.0	3.4	2.9
Fluid intelligence score	2.9	6.0	15.7	-0.0	3.8	4.0	2.1	3.2	2.6	1.8	3.5	0.5	0.9	3.0	1.0	-0.8
Gout (self-reported)	2.9	4.0	40.6	-6.4	-1.1	-0.7	0.8	-0.6	-1.5	-0.9	-0.5	-0.4	1.8	0.7	-1.5	-0.2
Type 2 Diabetes (T2D) (2012)	2.7	3.1	6.4	1.7	1.5	1.3	2.4	1.7	1.2	2.1	2.4	1.0	2.5	1.8	1.4	0.6
Hearing difficulty/problems: Yes	2.5	3.9	12.7	0.7	0.7	-0.1	2.6	1.7	1.0	2.5	1.2	1.8	3.6	0.9	2.5	2.8
Coronary Artery Disease (CAD)	2.4	2.9	12.0	0.2	-1.8	-2.6	-1.1	-1.8	-1.8	-1.3	-1.7	-0.8	-1.0	-0.6	-1.1	-3.5
Headache pain in last month	2.4	4.2	18.5	-4.3	-2.0	-2.7	0.8	-1.2	-0.1	-2.3	-1.6	-2.5	0.1	-0.6	-2.3	-1.5
Medication: Allopurinol	2.4	3.2	33.1	-5.8	-0.4	0.1	0.7	-0.5	-1.6	-0.6	-0.2	-0.2	1.0	1.2	-1.1	-1.2
Alzheimer’s Disease (in mother)	2.2	2.6	7.2	-2.1	-1.9	-1.3	-0.7	-1.2	-2.7	-1.9	-1.9	-0.4	-0.8	-0.8	-2.2	-1.6
HDL Cholesterol	2.2	3.7	10.1	2.1	2.6	3.2	2.2	1.9	1.3	1.8	2.0	2.0	1.0	1.4	1.3	-0.4
Pulse wave peak to peak time	2.2	2.6	6.9	-2.2	-1.7	-2.6	-0.8	-1.4	-1.5	0.7	-1.6	1.1	1.5	-1.0	1.1	2.2
Intelligence (Savage-Jansen 2018)	2.1	6.4	18.6	0.4	4.3	3.9	1.9	3.2	2.0	2.1	3.5	1.0	0.2	3.0	1.6	1.4
Had other major operations	2.1	2.6	5.8	2.4	2.1	1.9	-0.4	1.6	-0.7	1.8	2.0	0.0	0.5	2.4	1.6	0.7
Ever had stillbirth, spontaneous miscarriage or termination	2.1	2.2	4.1	-1.2	-1.3	-0.7	-1.4	-1.3	-1.9	-2.0	-1.6	-1.1	-1.7	-1.2	-1.9	-1.5
Back pain experienced in last month	2.1	3.0	15.9	4.0	1.1	-0.2	0.5	1.0	-1.1	2.1	1.3	1.9	1.8	1.7	1.7	0.9
Pain type(s) experienced in last month: Hip pain	2.1	2.6	6.9	2.0	1.2	0.3	-0.1	1.1	-0.5	2.5	1.2	0.5	2.1	2.2	2.6	1.8
Hypothyroidism (self reported)	2.0	4.6	7.9	-1.0	-2.4	-2.6	-2.1	-1.9	-0.3	-2.8	-2.5	-1.4	-2.4	-2.8	-2.5	-1.6
Hypothyroidism/myxoedema (self-reported)	2.0	3.8	7.3	-0.4	-1.7	-1.7	-2.3	-1.6	-0.4	-2.7	-2.0	-2.1	-2.7	-1.6	-2.6	-1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.0	2.4	12.3	-1.8	-0.8	-1.1	-3.0	-1.2	-3.5	-0.8	-0.6	-0.9	-0.9	0.1	-0.6	0.9
Bilateral oophorectomy (both ovaries removed)	1.9	2.1	5.5	1.2	0.8	-0.5	1.6	0.5	0.9	2.1	1.1	2.2	2.3	1.0	1.9	1.1
Pulse wave Arterial Stiffness index	1.9	2.3	6.3	2.0	1.4	2.5	0.5	1.0	1.2	-0.8	1.3	-1.3	-1.9	0.7	-1.1	-2.3
Falls in the last year	1.8	2.4	6.0	2.0	1.9	1.4	1.1	1.4	1.2	1.8	1.9	0.7	1.1	2.4	1.4	-0.3
Medication: Omeprazole	1.8	2.1	6.4	-1.1	-1.6	-2.5	-0.5	-1.4	-1.7	-1.4	-1.5	-1.7	-0.2	-1.5	-1.4	0.7
Age at last live birth	1.8	2.7	7.8	-1.4	-0.1	1.1	-1.7	-0.3	-1.4	-2.4	-0.4	-2.8	-2.3	0.0	-2.3	-1.7
Illnesses of father: High blood pressure	1.8	2.2	8.1	-1.6	-2.0	-2.1	-1.4	-1.4	-2.9	-1.1	-1.6	-0.3	0.3	-0.9	-1.1	-0.3
Ever highly irritable/argumentative for 2 days	1.7	2.0	4.9	-1.4	1.9	1.4	2.2	2.0	1.4	0.5	2.2	-0.2	0.4	1.0	0.3	1.1
Exposure to tobacco smoke outside home	1.7	2.3	5.6	1.6	1.4	0.6	2.4	1.3	1.7	1.3	1.5	1.0	2.3	2.0	0.7	0.4
Mineral and other dietary supplements	1.7	2.2	6.6	-1.0	-1.5	0.0	-1.8	-1.4	0.1	-2.1	-1.3	-2.6	-1.3	-0.7	-2.1	-1.1
Pain experienced in last month	1.7	2.9	5.6	-1.6	-1.8	-0.5	-1.3	-1.8	-0.3	-2.3	-1.8	-1.1	-2.4	-2.4	-1.9	-1.3
Schizophrenia vs Biploar Disorder	1.6	2.1	7.6	-2.8	-0.8	-1.9	1.1	-0.1	2.1	-1.0	-0.3	-0.2	1.6	-1.6	-1.3	-1.3
Eye problems/disorders: Cataract	1.6	1.9	7.2	0.8	1.3	1.4	2.7	1.4	2.0	1.0	1.1	1.3	1.5	0.9	0.7	-0.4
Supplements: Fish oil (including cod liver oil)	1.6	2.1	10.0	1.0	1.1	0.4	1.4	0.7	-0.3	2.1	0.9	3.2	1.3	0.5	2.3	0.4
Risk taking	1.6	2.3	8.0	-2.8	-1.4	-2.8	-1.0	-1.1	-1.2	-1.4	-1.5	0.0	-0.6	-1.5	-1.0	0.8
Supplements: Calcium	1.6	1.7	8.0	0.0	0.5	-0.7	2.8	2.1	1.6	0.6	1.0	-0.0	1.9	-0.5	0.1	1.3
Neuroticism (2016)	1.5	2.1	4.8	0.8	-2.0	-0.8	-2.0	-2.2	-1.8	-1.1	-1.9	-0.7	-1.1	-1.7	-0.5	0.6
Chronic bronchitis/emphysema (father)	1.5	1.7	3.5	1.4	1.6	0.9	1.9	1.6	1.7	0.8	1.6	0.6	1.1	0.8	0.6	1.4
Pain all over the body in last month	1.5	1.6	3.7	0.1	1.4	0.6	1.7	1.9	1.3	0.7	1.5	0.7	1.6	0.3	0.6	1.9
Pulse wave reflection index	1.5	1.8	6.3	0.9	1.6	2.5	0.3	1.4	1.3	-1.2	1.4	-1.0	-1.5	0.4	-1.7	-0.5
Bipolar Disorder (2018)	1.4	2.3	4.7	0.8	1.4	1.1	1.0	2.2	1.2	1.8	1.9	1.0	1.6	1.8	1.5	1.6
Prostate Cancer	1.4	2.0	3.4	-1.2	-1.2	-1.8	-1.3	-1.5	-1.7	-1.8	-1.5	-1.6	-1.4	-1.1	-1.3	-0.5
Blood Platelet Count	1.4	16.0	50.1	-4.8	-4.5	-2.2	-7.1	-4.1	-6.2	-2.8	-5.1	-1.1	-3.6	-1.8	-1.6	-1.2
Vitamin and mineral supplements	1.4	1.9	5.3	1.1	-1.2	-0.3	-1.5	-1.2	0.4	-2.0	-1.0	-2.3	-1.6	-1.2	-1.9	-0.2
Multivitamins +/- minerals	1.4	1.7	3.7	-0.5	1.6	1.1	1.2	1.2	-0.2	1.9	1.2	1.9	0.6	1.7	1.8	-0.6
Average weekly red wine intake	1.4	2.0	9.5	1.6	-0.3	-0.3	-1.2	-1.1	-2.3	-0.8	-0.9	0.8	-1.7	-0.2	-0.9	-3.1
Medication: Bendroflumethiazide	1.4	2.2	13.5	3.7	1.7	1.1	0.5	1.3	0.1	1.0	1.7	1.4	1.0	1.3	0.3	0.2
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	7.1	-1.4	-1.4	-2.7	0.6	-1.1	-1.7	-0.9	-1.2	-0.5	0.6	-1.4	-1.1	0.7
HbA1C	1.3	1.5	3.6	-0.6	-1.2	-0.0	0.3	-1.0	0.7	-1.9	-1.0	-1.4	-0.8	-1.8	-1.9	-1.4
Smoking Status	1.3	3.1	6.6	0.4	-2.0	-2.3	-1.4	-2.6	-1.6	-1.9	-2.5	0.0	-1.6	-1.7	-1.6	-1.6
Eye problems/disorders: None of the above	1.3	1.5	4.4	-0.9	-0.9	-0.8	-2.1	-1.0	-2.1	0.2	-0.9	0.6	-0.9	-0.9	0.7	2.1
Migraine (self-reported)	1.3	1.6	6.8	-2.6	-1.5	-1.5	0.5	-0.1	0.9	-1.2	-0.9	-0.7	0.5	-1.8	-1.2	0.4
Medication: Seretide 50 evohaler	1.3	1.5	3.1	0.8	1.8	0.6	1.4	1.0	1.2	1.3	1.5	1.4	1.0	1.7	1.0	0.1
Ever had bowel cancer screening	1.3	1.6	4.8	0.5	0.6	0.2	2.0	1.4	1.2	1.2	1.3	-0.3	2.2	1.6	0.8	1.0
LDL Cholesterol	1.2	1.9	3.6	-0.4	-1.7	-1.2	-0.5	-1.9	-0.1	-1.7	-1.4	-1.8	-1.6	-1.3	-1.4	-1.5
Medication: Ramipril	1.2	1.6	6.8	-1.8	-1.3	0.1	0.7	-0.5	-0.3	-1.8	-0.8	-1.0	0.7	-1.1	-2.6	-1.1
Frequency of tiredness / lethargy in last 2 weeks	1.2	1.9	6.9	1.1	-0.4	-0.2	-1.9	-1.4	-2.6	-1.3	-1.1	-1.4	-1.8	0.1	-1.1	-1.3
Lung cancer (father)	1.2	1.4	6.4	0.5	0.9	0.8	1.8	0.5	2.5	0.9	0.9	0.1	1.9	0.9	0.4	0.2
Number of children fathered	1.2	1.4	7.7	-0.3	-1.6	-2.8	-0.0	-1.4	0.1	-0.2	-1.4	0.6	0.3	-1.6	0.0	0.7
Knee pain experienced in last month	1.2	1.8	8.7	2.2	0.0	-0.2	-3.0	-1.5	-1.8	0.4	-0.7	-0.3	-1.6	0.7	1.0	-0.1
Major Depression (MDD)	1.1	1.4	7.5	0.9	-1.0	-0.8	-0.5	-0.9	-1.8	-0.8	-0.8	0.8	-0.3	-0.8	-1.1	-2.7
Age at First Birth	1.1	1.5	4.9	0.3	1.4	0.6	2.2	1.8	1.0	0.8	2.0	0.2	1.6	0.9	0.3	0.4
Average weekly spirits intake	1.1	1.4	5.9	1.2	1.4	0.9	0.4	0.8	0.3	1.7	1.1	0.3	0.3	2.4	1.4	-0.8
Had menopause	1.1	1.4	4.1	1.0	-0.3	-0.6	1.8	0.9	1.2	1.2	0.4	1.6	2.0	-1.1	1.1	-0.4
Alcohol intake frequency.	1.1	2.6	6.9	-1.8	-2.2	-2.4	-1.4	-2.6	-1.2	-0.7	-2.2	-0.7	-1.1	-1.3	-0.1	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	7.7	-1.2	-0.1	-0.8	1.0	-0.1	-0.1	1.5	-0.0	0.4	1.1	0.1	1.7	2.8
Osteoporosis (self-reported)	1.1	1.4	4.9	-0.8	0.9	-0.3	1.1	1.4	2.2	1.2	1.5	-0.0	1.6	1.1	1.0	0.3
Primary Biliary Cirrhosis	1.0	1.4	6.9	-2.6	-1.0	-0.3	1.0	-0.6	1.4	0.1	-0.5	-0.2	0.4	-2.2	0.5	1.0
Ever had hysterectomy (womb removed)	1.0	1.1	3.7	0.9	0.2	0.6	0.5	0.1	-0.5	1.9	0.2	1.5	1.6	0.7	1.9	0.4
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.2	8.6	-1.8	-0.6	1.2	-1.0	-1.1	-0.7	-2.4	-0.8	-0.9	-1.8	-0.2	-2.9	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.1	3.2	-0.8	-0.5	-0.3	1.0	-0.6	1.5	-1.5	-0.4	-0.4	-0.7	-1.2	-1.8	-1.5
Shortness of breath walking on level ground	1.0	1.2	3.5	-0.3	-0.9	-1.1	-0.8	-1.4	-0.7	-1.0	-1.3	-1.4	-1.2	-0.0	-0.8	-1.9
Emphysema/chronic bronchitis	1.0	1.1	3.5	-0.7	0.6	1.0	1.9	1.7	1.7	-1.0	0.6	-0.1	0.2	-0.1	-1.5	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	5.0	2.2	1.9	1.8	0.1	0.8	0.7	2.0	1.6	0.7	0.3	1.7	1.9	0.4
Heart attack/myocardial infarction (self-reported)	1.0	1.3	5.3	0.2	1.2	0.3	0.8	0.9	-1.1	1.4	1.2	1.1	1.4	2.3	0.6	0.5
Diverticular disease/diverticulitis (self-reported)	0.9	1.0	2.4	0.3	-1.1	0.0	-0.4	-1.5	-0.5	-1.6	-1.3	-0.7	-1.0	-0.3	-1.3	-1.4
Heart attack	0.9	1.1	4.0	-0.2	1.0	0.2	0.7	0.8	-1.2	1.4	1.0	1.0	1.3	2.0	0.8	1.1
Happiness	0.9	1.1	2.9	-0.5	1.1	0.5	1.0	1.7	1.0	-0.6	1.4	-1.7	1.1	0.7	-0.8	0.8
Chronic bronchitis/emphysema (mother)	0.9	1.0	2.9	0.2	0.7	0.5	1.7	0.5	1.5	0.9	0.9	-0.1	1.2	-0.1	1.2	1.7
Number of full brothers	0.9	1.2	3.5	-0.3	-1.5	-1.4	0.2	-0.9	0.6	-1.0	-1.4	-0.1	-0.2	-1.9	-0.5	1.8
Suffer from ‘nerves’	0.9	1.4	5.2	-1.1	-1.6	-1.5	1.6	-0.7	-0.0	-0.8	-1.3	0.3	0.5	-2.3	-0.3	1.0
Had major operations	0.9	1.1	4.4	0.5	0.7	-0.3	1.2	0.7	0.4	1.3	1.0	1.4	2.1	0.5	1.1	0.3
Handedness (chirality/laterality): Left-handed	0.9	1.1	6.0	2.4	0.7	0.4	1.4	0.6	1.7	0.4	0.7	0.2	0.0	0.8	0.1	-0.8
Qualifications: nursing, teaching	0.9	1.4	3.2	0.7	1.6	0.7	0.5	1.5	-0.2	1.5	1.8	-0.1	1.3	1.6	1.3	1.3
Medication: Gliclazide	0.9	1.0	4.0	1.6	-0.2	-0.7	-2.0	-1.0	-1.2	-0.7	-0.3	-0.7	-0.9	0.6	-0.9	-0.9
Medication: Blood pressure	0.9	1.7	4.4	1.5	1.9	2.1	1.2	1.5	0.4	0.6	1.9	0.2	0.9	1.5	-0.4	-0.1
Alcohol drinker status: Never	0.9	1.1	4.2	0.5	-0.4	0.3	-1.6	-1.7	-1.0	-0.5	-1.2	-0.3	-2.0	0.5	-0.2	-1.0
Mean Putamen Volume	0.8	0.9	3.2	0.8	0.1	-0.1	1.3	0.2	0.4	1.3	0.2	0.7	1.8	-0.2	1.1	1.6
Blood Red Count	0.8	7.9	21.4	3.4	4.6	4.6	1.7	2.8	-0.7	1.5	3.6	1.2	-0.4	4.2	0.7	-1.4
Current tobacco smoking	0.8	1.4	3.2	-0.9	-1.3	-0.4	-1.6	-1.8	-0.7	-1.0	-1.8	0.5	-1.7	-1.1	-0.5	-0.2
Age when periods started (menarche)	0.8	1.8	5.7	-1.9	-1.7	-2.3	0.1	-0.9	0.0	-1.2	-1.3	-2.4	0.6	-1.0	-1.0	0.2
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	5.5	0.5	-0.8	-0.4	-2.4	-0.8	-0.6	0.2	-0.8	0.9	-0.3	-0.7	0.8	0.3
Sitting height	0.8	5.5	27.1	5.2	-1.0	0.3	-4.4	-2.8	-2.8	0.0	-1.5	-1.2	-1.7	-0.6	0.8	0.2
Breastfed as a baby	0.8	0.9	3.8	0.0	0.3	-0.5	2.0	1.2	1.3	0.3	0.4	1.1	1.8	-0.5	-0.0	0.3
Birth weight	0.8	1.7	4.6	1.5	-0.9	-2.1	1.9	-0.5	0.1	0.3	-0.7	2.1	1.8	-1.6	0.4	0.4
Neck or shoulder pain in last month	0.8	1.2	4.6	1.6	0.1	-0.1	0.2	-0.1	-0.3	1.1	-0.2	2.2	1.1	1.6	0.9	-1.6
Illnesses of father: Heart disease	0.8	1.2	3.9	-1.0	-0.9	-0.9	-0.4	-1.2	-2.0	-0.8	-1.2	-0.2	-0.9	-0.1	-1.0	-1.8
Commuting to job workplace: Walk	0.8	0.9	2.7	1.3	1.1	1.6	1.5	0.9	0.6	0.4	0.9	0.3	-0.2	0.8	0.2	-0.6
Irritability	0.8	1.4	4.0	0.2	1.6	1.8	0.8	1.2	2.0	0.4	1.4	-0.1	0.2	1.3	0.4	1.5
Alcohol drinker status: Previous	0.8	0.9	3.2	-0.0	0.9	1.4	-1.1	0.7	0.7	-0.7	0.7	-1.1	-1.8	0.4	-0.7	-0.8
Bipolar Disorder or Schizophrenia	0.7	1.7	2.7	-1.3	1.3	0.8	1.2	1.6	1.6	1.5	1.6	0.8	1.4	1.2	1.1	1.0
Worry (Nagel 2018)	0.7	1.4	4.3	-0.7	-2.1	-1.2	0.5	-1.2	-0.3	-1.3	-1.8	-0.8	-0.3	-2.1	-0.7	0.3
Cardiovascular Disease	0.7	2.5	7.4	-0.1	-0.2	0.9	-2.0	-0.3	-1.0	-2.2	-0.3	-2.7	-2.2	0.2	-2.5	-1.6
Lung FVC	0.7	3.5	12.7	-3.6	-2.2	-2.0	-0.1	-1.4	1.8	-2.0	-1.8	-1.5	-0.2	-2.1	-2.0	0.4
Sensitivity / hurt feelings	0.7	1.2	4.0	-2.0	-0.7	-0.7	-0.2	-1.0	0.2	-1.6	-0.8	-1.4	-1.0	-0.7	-1.6	0.2
Frequency of depressed mood in last 2 weeks	0.7	1.0	3.1	-1.2	-0.3	-0.1	-0.5	-0.8	-1.1	-1.4	-0.8	-1.6	-1.8	-0.9	-0.6	0.6
Diabetes (mother)	0.7	0.9	3.1	1.0	0.4	-0.2	1.8	0.4	1.3	0.7	0.2	1.8	0.8	-0.5	0.6	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	1.8	-0.2	-0.9	-1.2	-0.5	-1.1	-1.0	-1.2	-1.3	-0.9	-1.3	-1.3	-0.5	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.7	6.3	-1.8	-0.2	1.6	-0.5	-0.7	-0.3	-2.1	-0.5	-1.1	-1.5	0.0	-2.5	-1.0
Medication: Levothyroxine sodium	0.7	1.1	2.7	-0.1	-0.9	-0.8	-0.3	-0.5	0.9	-1.5	-0.8	-1.5	-1.1	-1.2	-1.6	-1.1
High blood pressure (mother)	0.7	0.9	2.4	0.3	1.1	1.1	1.2	0.6	1.5	1.1	0.8	1.2	0.5	0.6	0.9	0.8
Number of incorrect matches in round	0.7	1.1	4.9	-0.5	-1.6	-2.2	0.3	-1.3	-0.5	-0.4	-1.2	1.0	1.0	-1.2	-0.1	-0.3
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	2.8	0.8	1.3	1.1	0.6	1.7	0.4	0.0	1.5	-0.6	0.3	1.1	-0.3	0.0
Mouth/teeth dental problems: Dentures	0.7	1.2	4.9	1.2	-0.7	-1.1	-1.2	-1.4	-2.2	0.3	-0.8	1.5	-0.5	-0.4	0.5	0.8
Medication: Cholesterol lowering	0.7	1.1	4.6	0.1	0.9	1.4	-1.8	-0.1	-1.0	0.6	0.3	-1.0	-1.0	2.2	0.5	0.0
Illnesses of mother	0.7	0.9	4.9	0.1	-1.0	-0.6	-2.2	-0.2	-1.0	-0.9	-0.8	-0.6	-1.3	-0.8	-0.7	-0.5
Length of working week for main job	0.7	0.8	2.6	-1.3	-0.3	-0.9	0.1	-0.4	-0.3	0.9	-0.4	1.4	0.4	-0.4	1.1	1.6
Tense / ‘highly strung’	0.7	1.2	3.0	-0.1	-1.3	-0.6	1.1	-1.6	0.2	-1.2	-1.7	-0.1	-0.9	-1.6	-0.8	-0.9
Loud music exposure frequency	0.7	0.8	4.2	0.5	0.8	-0.1	-0.4	0.4	1.6	0.7	1.0	-0.2	0.2	-0.3	0.8	2.0
Comparative body size at age 10	0.7	2.0	4.6	-0.2	2.1	1.4	0.6	2.0	0.6	1.8	2.1	0.1	0.8	1.7	1.8	0.7
Osteoarthritis (self-reported)	0.7	0.9	5.7	2.4	0.2	0.5	0.6	-0.1	0.7	0.5	-0.1	1.2	-0.2	-0.1	0.3	-1.7
Medication: Aspirin	0.7	0.9	2.7	1.2	0.8	0.8	0.4	0.2	-0.4	1.3	0.5	1.6	0.3	1.3	1.3	-1.0
Smoking status: Current	0.7	1.1	2.5	-1.0	-1.1	-0.2	-1.5	-1.4	-0.7	-1.0	-1.5	0.4	-1.6	-1.1	-0.6	-0.1
Wears glasses or contact lenses	0.7	0.8	2.2	0.5	1.1	0.5	0.5	1.0	1.5	0.9	1.3	-1.1	0.5	0.5	0.7	0.4
Medication: Atorvastatin	0.7	0.8	2.7	-0.8	1.1	0.4	-1.2	0.2	0.6	1.2	0.9	-0.5	0.0	1.6	1.2	0.2
Diastolic blood pressure, automated reading	0.7	2.1	8.0	0.6	-0.4	-0.2	-2.1	-0.9	-2.7	-0.8	-0.6	-0.8	-1.2	1.2	-1.0	-2.8
Heart disease (siblings)	0.7	0.8	4.8	-2.2	-0.5	-1.5	-0.8	-0.6	-1.0	-0.1	-0.8	0.1	-0.1	-0.0	-0.0	0.8
Reaction Time	0.6	1.1	2.8	-0.9	-0.8	-1.0	-1.3	-1.5	-1.0	-0.3	-1.2	-0.5	-1.4	-0.1	0.2	-1.7
Crohns Disease (2012)	0.6	0.9	2.2	1.5	1.0	0.5	-0.6	0.7	-1.0	1.1	1.1	0.6	0.3	1.3	1.3	0.3
Lupus	0.6	1.0	5.1	-2.3	0.0	0.1	-0.4	0.6	1.2	-1.2	0.1	-1.2	-0.7	-0.6	-1.4	-0.2
Ulcerative Colitis	0.6	0.8	1.9	1.1	1.3	0.2	1.0	0.9	0.9	0.4	1.4	-0.5	1.0	1.1	0.0	0.7
Blood White Count	0.6	4.6	11.6	-1.7	-2.9	-1.5	-3.4	-2.9	-0.8	-1.3	-3.2	-1.7	-1.9	-2.2	0.0	1.6
Systolic blood pressure, automated reading	0.6	1.6	6.6	-0.6	-0.8	-0.5	-2.2	-0.9	-2.6	-1.1	-1.0	-0.9	-1.4	0.5	-1.1	-1.0
Angina	0.6	0.8	1.9	-0.9	0.9	0.5	0.0	0.7	0.0	1.4	0.8	1.1	1.2	1.1	1.3	-0.0
Nervous feelings	0.6	1.2	6.0	-1.0	-1.2	-1.0	1.4	-0.5	0.3	-0.8	-1.2	0.2	-0.3	-2.4	-0.2	1.2
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	2.2	-0.8	-0.5	0.3	-0.7	-1.2	-0.9	-1.3	-0.9	-1.5	-1.5	-0.3	-0.7	-0.1
Hair/balding pattern: Pattern 2	0.6	0.8	3.7	-0.8	-0.3	-0.3	1.1	-0.4	0.3	1.3	-0.3	0.7	0.5	-0.3	1.9	1.4
Trunk fat-free mass	0.6	3.4	22.2	4.7	0.2	-0.3	-2.4	-1.8	-1.4	1.6	-0.3	1.1	-0.9	0.3	2.4	0.3
Trunk predicted mass	0.6	3.2	21.4	4.6	0.2	-0.4	-2.3	-1.7	-1.4	1.6	-0.3	1.0	-0.8	0.2	2.4	0.4
Health satisfaction	0.6	0.8	1.7	1.2	-1.0	-1.3	-0.6	-0.7	-0.5	-0.7	-0.6	-1.3	0.5	0.2	-0.8	-1.1
Medication: Blood pressure	0.6	1.1	2.7	-1.6	-0.9	-0.8	-0.5	-0.7	-0.9	-1.3	-0.7	-1.0	-0.3	-0.6	-1.6	-1.3
Angina (self-reported)	0.6	0.8	1.5	-0.9	1.1	0.7	0.0	0.9	0.3	1.2	0.9	1.0	1.0	1.1	1.1	-0.2
Family relationship satisfaction	0.6	0.8	3.1	0.4	0.9	0.9	0.2	0.8	0.7	-1.1	0.8	-1.8	-0.2	0.8	-1.3	-0.5
Leg pain on walking	0.6	0.7	2.2	1.3	-0.8	-0.2	-0.7	-1.0	-1.5	-0.6	-1.1	0.1	-1.0	-0.3	-0.2	-0.9
Medication: Aspirin	0.6	0.8	2.3	0.8	0.7	1.0	0.1	0.0	-0.0	1.1	0.3	1.3	0.1	1.5	1.0	-1.3
Supplements: Vitamin C	0.6	0.8	2.0	0.9	0.7	-0.7	1.3	0.5	-0.6	0.4	0.8	1.4	1.3	1.0	0.0	-0.1
Smoking status: Previous	0.6	0.9	3.3	1.0	0.8	-0.1	1.8	1.1	1.2	0.3	1.0	-0.1	1.4	0.4	-0.4	0.1
Friendships satisfaction	0.6	0.8	2.3	-0.6	0.7	0.8	1.4	1.5	0.7	0.6	0.7	0.5	1.5	0.3	0.5	0.7
Breast cancer (self-reported)	0.6	0.7	4.5	2.1	-0.2	0.2	-0.4	-0.1	1.0	-0.1	0.0	-0.8	-0.2	-0.6	0.1	1.6
Ever taken oral contraceptive pill	0.6	0.7	3.0	1.0	0.5	0.0	-0.3	0.4	0.4	1.3	0.2	1.6	-0.2	0.1	1.7	-0.5
Mother’s age at death	0.6	0.8	3.1	0.4	-1.0	-0.5	-0.2	-1.0	0.1	-1.2	-1.1	0.2	-0.9	-1.8	-0.9	-0.5
Fractured/broken bones in last 5 years	0.6	0.8	4.9	1.0	-0.0	0.6	-1.4	0.3	0.1	-0.7	0.2	-2.2	0.1	0.6	-1.0	-0.1
Crohns Disease (2017)	0.5	1.2	3.8	2.0	0.6	-0.4	0.3	0.5	-0.7	1.6	0.9	1.4	1.1	1.2	1.5	0.2
Heel T-Score	0.5	4.0	13.8	-3.3	0.8	2.3	3.7	-0.6	1.0	-2.4	0.3	-1.5	-1.4	0.3	-3.1	-1.1
Neuroticism	0.5	1.2	2.4	-1.2	-1.3	-0.8	-0.1	-1.4	-0.2	-1.5	-1.6	-1.0	-1.1	-1.4	-0.8	0.2
Medication: Metformin	0.5	0.8	2.2	-0.8	-0.9	-1.5	-1.3	-1.1	-0.2	0.3	-0.7	1.2	0.2	-0.9	0.6	0.3
Hand grip strength (right)	0.5	1.3	6.0	2.1	1.2	0.5	-1.3	-0.6	-0.1	-0.1	0.6	-0.8	-2.5	1.0	0.3	-0.1
Qualifications: None of the above	0.5	1.1	3.0	-0.4	-1.7	-0.6	-1.2	-1.4	-0.2	-0.8	-1.7	-0.8	-1.0	-1.6	-0.2	0.3
Mouth/teeth dental problems	0.5	0.8	2.1	-1.2	0.8	1.4	0.3	1.2	0.4	-0.7	1.0	-1.1	-0.3	0.5	-1.2	-0.2
Alcohol intake versus 10 years previously	0.5	0.8	3.8	-1.9	-0.6	-0.8	0.3	-1.0	1.0	0.0	-0.7	0.3	-1.0	-1.2	0.6	-0.4
Qualifications: A levels/AS levels or equivalent	0.5	1.1	3.8	0.6	1.3	1.9	0.2	1.1	-0.2	1.0	1.1	1.7	0.4	1.0	0.9	-0.8
Asthma	0.5	1.0	2.6	1.6	1.5	1.3	0.9	1.0	0.8	0.0	1.2	-0.2	-0.5	1.3	-0.2	-1.1
Depression (self-reported)	0.5	0.6	3.1	-0.3	-0.5	0.1	-0.1	-0.2	0.3	-1.4	-0.3	-0.8	-0.2	-0.6	-1.8	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	1.9	-0.4	0.9	0.9	0.3	0.7	-0.1	1.1	0.9	0.9	1.4	0.6	1.1	0.8
Hair/balding pattern: Pattern 4	0.5	1.3	2.6	0.3	1.5	1.1	1.5	1.5	0.1	1.0	1.6	1.2	1.4	0.6	0.3	1.2
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	2.1	-1.4	-0.8	-1.5	0.3	-0.8	0.4	-0.1	-1.0	-0.7	-0.3	-0.8	0.4	0.1
Arm fat-free mass (right)	0.5	2.5	14.3	3.8	-0.2	-1.2	-2.0	-1.7	-0.9	1.4	-0.4	1.0	-0.3	0.0	2.1	1.0
Qualifications: College or University degree	0.5	1.5	4.1	-1.5	1.3	0.9	1.7	2.0	1.3	-0.3	1.8	0.1	1.0	-0.1	-0.8	0.3
Medication for pain relief, constipation, heartburn	0.5	0.8	2.2	-0.9	-0.4	-0.5	-1.0	-0.5	0.3	-1.5	-0.3	-1.2	-1.0	-1.3	-1.3	-0.2
Medication: Ibuprofen	0.5	0.6	3.3	0.8	-0.3	-1.2	-1.1	-0.4	-1.8	-0.2	-0.2	0.5	0.2	1.0	-0.3	-0.1
Heart disease (mother)	0.5	0.6	1.7	0.4	-0.8	-0.6	0.4	-1.3	-0.9	0.1	-1.0	0.9	1.1	0.4	0.1	-0.8
Arm predicted mass (right)	0.5	2.6	13.8	3.7	-0.4	-1.1	-2.6	-2.0	-1.2	1.1	-0.7	0.7	-0.7	-0.0	2.0	0.8
Chest pain or discomfort	0.5	0.8	4.1	2.0	0.4	0.5	0.9	0.1	0.4	0.2	0.3	1.1	0.7	0.9	-0.1	-1.3
Whole body fat-free mass	0.5	2.9	19.3	4.4	-0.1	-0.8	-2.1	-1.7	-1.2	1.5	-0.4	0.8	-0.6	0.0	2.3	0.5
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	3.3	1.8	-0.6	-0.4	-0.5	-0.9	-0.2	0.7	-0.9	1.0	-0.2	0.0	1.4	-0.8
Medication for cholesterol	0.5	0.8	2.5	0.5	-0.9	-0.4	-1.1	-0.8	-0.6	-1.1	-1.2	-0.3	-1.6	-1.0	-0.3	-0.6
Whole body water mass	0.5	2.9	18.3	4.3	-0.2	-0.8	-2.2	-1.8	-1.3	1.5	-0.4	0.8	-0.6	0.0	2.2	0.5
Miserableness	0.5	0.8	3.1	-1.1	1.3	1.8	-0.3	1.2	-0.3	-0.3	0.8	0.2	-1.1	0.8	-0.3	0.4
High cholesterol (Self-reported)	0.5	0.8	2.4	-0.7	-0.8	-0.6	-0.5	-0.8	-1.6	-0.4	-0.9	-0.1	0.7	0.9	-1.1	-1.3
Medication: Lisinopril	0.5	0.6	1.1	1.0	-0.9	-0.8	-0.9	-0.5	-0.7	-0.8	-0.7	0.0	-0.8	-0.9	-0.9	-0.4
Arm fat-free mass (left)	0.5	2.4	14.3	3.8	-0.4	-1.1	-2.3	-1.8	-1.1	1.1	-0.7	0.7	-0.5	-0.1	1.9	0.6
Ever had prostate specific antigen (PSA) test	0.5	0.6	3.0	0.9	0.1	0.3	1.6	0.1	0.2	-0.1	0.2	0.6	0.4	0.1	-0.3	-1.7
Age started oral contraceptive pill	0.5	0.6	4.1	2.0	0.0	-0.3	-0.0	0.4	0.7	0.7	0.3	0.6	1.0	0.2	0.8	0.7
Myopia	0.5	0.8	5.1	-0.8	-0.0	0.3	-1.5	-0.1	-0.4	-0.5	0.2	-2.3	-0.7	0.7	-0.7	-0.0
Pack years of smoking	0.5	0.7	1.8	1.3	-0.8	-1.0	0.5	-1.2	0.4	-1.0	-1.0	-0.8	-0.5	-1.0	-0.6	0.6
Arm predicted mass (left)	0.5	2.6	16.3	4.0	-0.2	-1.0	-2.4	-1.8	-1.0	1.4	-0.5	0.7	-0.3	0.1	2.1	0.7
Depression (Nagel 2018)	0.4	0.6	2.4	-0.8	-0.2	-0.6	-0.1	-0.5	-0.7	-1.1	-0.5	-1.5	-0.9	-0.7	-0.6	0.1
Irritable Bowel Disease (IBD)	0.4	0.9	2.9	1.7	0.8	-1.0	0.7	0.6	0.3	0.9	1.1	0.5	1.3	0.5	0.9	1.1
Ulcerative Colitis (UC)	0.4	0.7	2.6	0.4	0.8	-1.0	0.9	0.6	0.8	-0.1	1.1	-0.7	0.9	-0.3	-0.2	1.6
Body Mass Index (BMI) (2010)	0.4	0.5	3.7	0.2	-0.1	-0.4	0.6	0.6	1.9	0.4	0.4	-0.6	0.5	-0.1	0.3	0.9
Fasting Glucose	0.4	0.5	2.7	0.1	0.0	-0.2	-0.5	-0.1	-1.2	0.2	-0.1	-1.0	0.1	0.5	0.4	1.6
Schizophrenia (2014)	0.4	0.9	7.3	-2.7	0.4	-0.3	0.7	0.5	1.4	0.1	0.5	0.2	0.2	-0.5	-0.0	0.6
Height	0.4	8.7	60.4	7.8	2.8	4.3	-1.5	-0.3	0.5	2.5	1.9	0.9	-1.6	0.7	3.2	0.2
Systolic Blood Pressure	0.4	2.0	4.1	-0.4	0.3	1.9	-1.8	-0.3	-1.9	-1.4	-0.2	-1.7	-2.0	1.2	-1.7	-1.5
Allergy or Eczema	0.4	1.2	2.8	0.2	1.2	0.2	1.6	1.6	0.9	0.8	1.3	1.7	0.7	0.6	0.3	1.2
Type 2 Diabetes (T2D) (2018)	0.4	0.7	3.7	-0.1	-0.3	-0.3	-1.9	-0.5	-0.3	0.2	-0.4	0.4	-0.3	0.7	0.3	-1.8
Hand grip strength (left)	0.4	1.1	4.5	2.1	1.4	0.1	-0.1	0.3	0.7	0.6	1.2	-0.3	-1.4	0.6	0.7	1.4
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.9	1.1	0.3	0.7	-0.5	0.2	1.4	0.4	0.5	-1.1	-0.0	0.3	0.7	-0.2
Medication for hormone replacement therapy	0.4	0.4	1.7	-0.4	-0.4	-0.7	-0.1	-0.4	0.1	0.9	-0.5	1.3	0.6	-0.3	1.0	0.5
Medication: Co-codamol	0.4	0.4	1.3	0.4	0.8	0.2	-0.1	1.0	-0.3	0.6	0.9	1.2	0.5	0.8	0.4	0.4
Pack years adult smoking proportion	0.4	0.6	2.1	1.5	-0.5	-0.5	-0.0	-1.1	-0.1	-0.8	-0.8	-0.9	-0.6	-0.4	-0.4	0.7
Leg fat-free mass (left)	0.4	2.2	15.0	3.9	-0.1	-0.9	-1.4	-1.3	-1.0	1.5	-0.2	0.6	-0.1	-0.1	2.1	0.7
Average weekly fortified wine intake	0.4	0.4	1.2	0.1	0.7	0.8	-0.1	0.9	-0.6	0.7	1.1	0.4	0.8	0.7	0.3	-0.2
Relative age voice broke	0.4	0.7	1.8	1.2	0.2	0.6	-1.3	-0.7	-1.0	-0.4	-0.3	-0.3	-1.1	0.6	-0.6	-1.1
Medication: Atenolol	0.4	0.5	2.0	-1.2	0.2	0.1	-0.7	-0.2	-1.4	-0.1	0.2	-1.2	-0.1	0.7	-0.2	0.4
Leg predicted mass (left)	0.4	2.2	15.4	3.9	-0.0	-0.9	-1.4	-1.2	-0.9	1.6	-0.1	0.7	-0.1	-0.1	2.2	0.7
Past tobacco smoking	0.4	0.7	2.3	-1.1	-0.9	-0.5	-1.5	-1.0	-1.2	-0.4	-1.0	-0.1	-1.0	-0.3	0.2	-0.2
Illnesses of siblings	0.4	0.6	2.1	1.1	1.0	1.1	-0.1	0.8	0.7	0.0	0.9	-0.4	-1.4	-0.1	0.3	0.3
Impedance of arm (right)	0.4	1.7	7.0	-1.2	1.4	2.1	2.6	1.7	1.0	-0.4	1.2	-0.3	0.5	0.1	-1.2	-0.5
Time employed in main current job	0.4	0.5	1.2	0.2	-0.1	-1.0	0.2	0.1	0.0	1.1	0.1	1.1	1.1	0.2	0.9	0.7
Father’s age at death	0.4	0.5	1.9	0.6	-0.8	-0.9	-0.3	-0.5	-0.1	-0.5	-0.8	0.7	-0.7	-1.4	-0.1	-0.7
Number of live births	0.4	0.5	2.4	0.7	0.9	1.5	-0.4	0.6	-0.3	0.1	0.7	-0.4	-0.1	0.6	-0.4	-1.1
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.5	-1.2	0.4	0.6	0.7	1.1	0.5	-0.0	0.7	-0.3	0.5	0.4	-0.4	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.4	2.6	0.3	-0.1	-0.7	-0.3	-0.1	-1.6	0.3	-0.1	1.2	0.4	0.8	0.3	0.1
Impedance of arm (left)	0.4	1.8	7.5	-1.5	1.2	1.8	2.7	1.7	1.0	-0.8	1.1	-0.6	0.3	0.0	-1.6	-0.4
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	1.5	1.2	1.0	1.0	0.5	0.7	-0.0	0.6	1.1	-0.5	0.8	1.2	0.3	-1.0
Wheeze or whistling in the chest in last year	0.4	0.6	2.1	0.2	1.1	1.0	1.4	0.9	0.2	-0.2	0.8	0.8	0.1	0.8	-0.4	-1.0
Mouth/teeth dental problems: Loose teeth	0.4	0.5	3.1	-0.0	-0.0	-0.1	0.3	-0.4	-0.1	1.2	-0.1	0.2	0.8	0.4	1.8	0.5
Mean time to correctly identify matches	0.4	0.8	2.6	-0.6	-0.7	-1.6	-0.4	-1.2	-0.8	-0.0	-1.0	0.2	-0.9	-0.4	0.3	-1.6
Comparative height size at age 10	0.4	2.0	12.0	3.5	1.4	1.6	-0.8	-0.1	-0.6	1.1	0.6	0.6	-1.3	0.5	1.4	1.5
Number of full sisters	0.4	0.5	1.3	0.3	0.6	0.4	1.1	1.1	0.6	0.5	0.6	0.6	0.7	1.1	0.3	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.4	-0.1	-0.8	-0.6	-1.1	-1.1	-1.2	-0.4	-0.9	-0.1	0.1	0.5	-0.7	0.0
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	3.7	0.8	0.2	-0.1	1.0	0.2	-0.4	0.5	0.0	1.9	0.6	-0.8	0.3	0.3
Illnesses of siblings: Diabetes	0.4	0.5	2.3	-0.7	-0.8	-0.4	0.2	-0.4	-0.5	-0.7	-0.6	0.4	0.4	0.0	-1.2	-1.5
Leg fat-free mass (right)	0.4	2.0	14.6	3.8	-0.3	-1.0	-1.2	-1.3	-0.9	1.5	-0.2	0.5	0.2	-0.2	2.0	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.4	-0.3	0.4	1.2	0.4	1.1	0.3	1.0	0.5	0.4	0.4	0.2	1.1	1.0
Asthma (self-reported)	0.4	0.9	2.4	1.5	1.5	1.0	0.6	0.8	0.4	0.2	1.1	-0.1	-0.6	1.4	0.1	-1.0
Leg predicted mass (right)	0.4	2.0	14.2	3.8	-0.3	-1.0	-1.2	-1.3	-0.9	1.4	-0.3	0.5	0.2	-0.2	2.0	0.7
Average weekly champagne plus white wine intake	0.4	0.6	3.1	-0.2	0.4	0.2	0.4	0.4	-0.0	0.9	0.5	1.8	1.1	0.5	0.7	-1.0
Hearing aid user	0.4	0.4	1.1	0.1	-0.1	-0.7	0.5	-0.5	-0.5	0.9	-0.3	0.6	1.0	-0.3	1.0	1.0
Financial situation satisfaction	0.4	0.4	1.6	-0.7	-0.5	-1.2	1.1	0.3	0.6	-0.2	-0.1	-0.2	1.3	-0.2	-0.3	0.3
Tinnitus: Yes, now most or all of the time	0.4	0.5	2.2	-0.1	-0.2	-0.1	-0.2	-0.2	0.3	1.2	-0.1	0.8	1.0	0.4	1.5	1.1
Eye problems/disorders: Glaucoma	0.4	0.5	1.4	-0.2	0.2	0.1	1.1	0.8	0.9	-0.8	0.5	0.2	0.1	0.0	-1.0	-1.2
Basal metabolic rate	0.4	2.4	15.5	3.9	-0.1	-0.9	-2.0	-1.6	-1.1	1.3	-0.4	0.5	-0.5	-0.0	2.0	0.5
Ever depressed for a whole week	0.4	0.6	2.7	1.6	0.8	0.6	0.1	0.8	-0.4	0.6	0.9	0.2	0.5	0.9	0.5	-0.4
Unable to work because of sickness or disability	0.4	0.5	1.8	-0.3	-0.9	-1.2	-0.4	-0.4	-1.3	-0.1	-0.6	-0.4	0.7	-0.5	-0.0	0.9
Cholesterol lowering medication	0.4	0.6	2.9	-0.6	-0.8	-1.4	0.2	-0.7	0.1	0.2	-0.5	0.3	1.7	-0.2	-0.3	-0.8
Basal cell carcinoma (self-reported)	0.4	0.4	1.3	-1.1	-0.7	-0.8	-1.0	-0.4	0.2	0.1	-0.7	0.5	0.3	-0.7	0.4	0.7
Schizophrenia (2018)	0.3	0.7	5.5	-2.3	0.5	0.1	0.7	0.3	1.1	0.5	0.6	0.2	0.6	0.1	0.3	0.0
Ovarian Cancer	0.3	0.4	1.2	0.2	0.3	0.4	-0.6	0.2	0.2	-0.4	-0.0	-1.0	-1.1	0.7	-0.3	1.0
Bipolar Disorder (2011)	0.3	0.3	1.4	-0.9	0.6	0.4	0.5	1.2	-0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Waist Hip Ratio (WHR)	0.3	1.2	5.1	-2.3	-1.2	-0.8	0.0	-0.5	1.1	-1.2	-1.1	-0.8	0.8	-0.7	-1.4	0.4
Chronotype (morning person)	0.3	0.7	3.1	-0.4	-0.7	-0.1	1.2	-0.1	0.4	-0.9	-0.1	-1.8	1.1	-0.4	-1.3	0.3
Diabetes (father)	0.3	0.4	1.6	1.0	0.2	0.0	1.2	-0.4	-0.3	0.6	0.0	0.7	-0.8	0.2	0.8	-0.6
Severe depression (siblings)	0.3	0.4	0.9	0.7	-0.5	-0.3	-0.1	-0.6	-0.4	-0.9	-0.6	-0.7	-0.1	-0.4	-0.9	-0.7
Impedance of leg (right)	0.3	1.6	5.4	-2.3	1.3	2.2	0.6	1.1	0.7	-1.2	0.6	-0.4	-1.1	0.8	-1.7	-0.3
Hayfever, allergic rhinitis or eczema	0.3	0.8	2.0	0.2	0.8	-0.5	1.2	1.1	0.2	0.9	0.9	1.4	0.8	0.3	0.6	1.2
Impedance of leg (left)	0.3	1.6	7.4	-2.7	0.7	1.8	1.0	0.7	0.6	-1.5	0.2	-0.5	-0.7	0.4	-2.1	-0.4
Waist circumference	0.3	1.2	5.4	1.0	-1.2	-2.3	-1.5	-1.5	-0.3	-0.3	-0.9	-0.7	-0.2	-1.0	0.2	1.0
Alcohol usually taken with meals	0.3	0.5	1.7	0.7	1.0	0.3	-0.3	0.4	-0.2	0.6	0.8	0.8	-0.3	0.8	0.4	-1.3
Financial difficulties in last 2 years	0.3	0.4	2.1	-1.4	0.0	-0.4	0.5	0.2	0.0	0.2	0.0	0.4	1.2	0.6	0.1	0.4
Allergy	0.3	0.6	1.6	-1.3	-0.9	0.3	-1.1	-1.2	-0.1	-0.6	-1.0	-0.9	-0.2	-0.6	-0.4	0.3
Weight	0.3	1.4	8.7	3.0	-0.3	-1.0	-1.8	-1.3	-0.6	0.7	-0.3	-0.3	-0.4	-0.0	1.2	0.3
Hip circumference	0.3	1.2	5.7	2.4	-0.2	-1.2	-1.7	-1.1	-1.4	0.5	-0.3	-0.2	-0.8	-0.4	1.0	0.3
Pulse rate	0.3	0.6	2.7	1.6	0.5	0.9	0.4	0.3	0.1	0.0	0.6	-0.5	0.3	1.2	-0.2	-1.2
Noisy workplace	0.3	0.4	1.5	-0.1	0.1	-0.4	-0.0	0.2	0.3	1.0	0.4	0.7	1.2	0.6	0.7	0.6
Standing height	0.3	2.9	22.4	4.7	1.5	2.1	-0.9	-0.8	-0.7	1.4	0.6	0.9	-0.9	0.6	1.7	0.3
Exposure to tobacco smoke at home	0.3	0.3	1.0	0.4	-0.7	-0.6	0.5	-0.3	-0.5	-0.4	-0.4	-1.0	0.9	0.5	-0.6	0.1
Glaucoma (self-reported)	0.3	0.3	1.1	-0.6	-0.5	-0.5	-0.3	-0.4	0.3	-1.1	-0.4	-0.0	-0.6	-0.7	-0.9	-0.4
Worry too long after embarrassment	0.3	0.6	1.8	0.6	-0.7	-1.1	0.6	-0.7	0.4	-0.9	-0.9	-0.1	-0.2	-1.3	-0.7	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.4	0.2	0.6	0.4	-0.1	0.6	-0.7	0.5	0.6	-0.1	0.5	1.2	0.5	1.0
Age at first live birth	0.3	0.6	1.8	-1.1	-0.1	0.0	-0.3	0.4	0.1	-1.3	-0.1	-1.4	-1.0	-0.4	-1.0	0.2
Pulse rate, automated reading	0.3	1.0	2.4	1.0	-1.6	-0.5	-1.4	-1.3	-0.1	-0.9	-1.1	-1.0	0.0	-0.3	-0.9	-1.4
Overall health rating	0.3	0.7	2.5	1.0	-0.3	-0.8	0.2	-0.0	-1.1	0.9	0.0	0.6	1.6	1.0	0.9	-0.5
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.6	-0.2	-0.8	-0.6	0.4	0.6	0.8	-0.4	-0.3	0.4	1.2	-0.7	-0.7	0.3
Loneliness, isolation	0.3	0.5	3.0	-0.6	0.3	0.2	-0.4	-0.2	0.0	0.1	0.0	0.1	-1.0	-0.7	1.0	1.7
Long-standing illness, disability or infirmity	0.3	0.5	1.5	0.8	1.1	0.3	-0.3	0.4	-0.2	0.6	1.1	0.0	0.4	1.2	0.4	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.5	-1.2	-0.8	-0.7	1.2	-0.4	1.0	0.2	-0.4	0.2	1.0	-0.9	0.1	0.7
Commuting to job workplace: Public transport	0.3	0.3	1.1	-0.9	0.9	0.4	0.8	0.3	1.0	0.1	0.7	0.2	-0.3	0.3	-0.0	-0.3
Average weekly beer plus cider intake	0.3	0.4	2.1	-0.4	0.4	0.5	0.7	0.3	0.1	0.8	0.2	0.2	0.4	0.6	0.8	1.4
Commuting to job workplace: Cycle	0.3	0.4	1.8	1.1	0.6	0.0	-0.5	0.1	-1.1	0.2	0.3	-0.0	-0.5	-0.1	0.4	1.3
Vascular/heart problems diagnosed by doctor	0.3	0.7	1.9	0.6	-1.1	-1.1	-0.9	-1.2	-0.6	-0.1	-1.4	0.4	-0.6	-0.9	0.6	0.6
Impedance of whole body	0.3	1.7	5.2	-2.3	1.0	1.9	2.0	1.3	1.0	-1.2	0.7	-0.5	-0.1	0.1	-2.0	-0.2
Depressed Affect (Nagel 2018)	0.2	0.4	1.1	-1.0	0.7	1.0	-1.0	0.3	-0.1	-0.1	0.1	-0.9	-0.6	0.7	0.2	0.6
Neuroticism (Nagel 2018)	0.2	0.5	1.2	-1.0	-0.8	-0.3	-0.1	-0.5	0.1	-1.0	-1.1	-1.0	-0.3	-1.1	-0.5	0.6
Alzheimer’s Disease (including proxy)	0.2	0.3	1.1	-0.9	-0.1	0.3	0.6	-0.3	-0.5	0.1	-0.5	1.0	-0.3	0.5	-0.3	-0.7
Breast Cancer	0.2	0.4	1.0	0.7	0.6	0.7	-0.8	0.4	-0.3	0.7	0.8	0.0	0.3	0.5	0.7	1.0
Rheumatoid Arthritis	0.2	0.3	1.2	-0.6	0.2	1.0	-0.2	0.4	-0.3	-0.1	0.3	-0.7	-0.0	0.8	-0.3	-1.1
Lung FEV1/FVC ratio	0.2	1.2	4.0	1.3	-0.3	-1.2	-0.6	-0.7	-1.5	1.3	-0.5	0.8	-0.0	0.5	1.6	2.0
Relative age of first facial hair	0.2	0.3	1.0	0.3	0.1	0.7	-0.2	-0.6	-0.9	0.7	-0.0	-0.6	0.1	1.0	0.8	-0.0
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	1.2	-0.7	-0.2	-1.1	0.1	0.1	-0.6	-0.6	-0.2	-0.8	-0.1	-0.4	-0.4	0.9
Townsend deprivation index at recruitment	0.2	0.3	1.4	0.2	-0.6	-0.7	0.6	-0.5	-0.6	-0.4	-0.4	-0.0	0.3	-0.8	-0.2	1.2
Maternal smoking around birth	0.2	0.3	0.9	0.3	0.4	0.2	0.7	0.6	0.9	0.4	0.4	-0.4	0.5	0.4	0.3	0.9
Fed-up feelings	0.2	0.3	1.6	-0.1	0.5	1.3	-0.3	-0.1	-0.1	-0.0	-0.2	-0.1	-1.0	0.8	0.3	0.1
Taking other prescription medications	0.2	0.2	0.9	-0.9	-0.3	-0.6	-0.1	0.3	-0.1	0.1	0.0	0.6	0.7	-0.1	0.0	0.9
Qualifications: CSEs or equivalent	0.2	0.3	1.2	-0.4	-0.5	-0.6	0.0	-0.2	0.2	0.5	-0.4	0.5	0.8	-0.0	0.7	1.1
High blood pressure	0.2	0.5	1.6	-0.5	0.6	0.8	0.4	0.9	0.0	-0.6	0.9	-0.8	0.1	0.3	-1.3	-1.0
Stomach or abdominal pain in last month	0.2	0.2	0.7	-0.6	-0.5	-0.8	-0.1	-0.7	-0.5	-0.1	-0.4	0.5	0.4	0.1	0.1	0.7
Body mass index (BMI)	0.2	0.8	4.4	0.8	-1.1	-2.1	-1.4	-1.1	-0.4	0.1	-0.7	-0.6	-0.0	-0.3	0.5	0.1
Forced vital capacity (FVC)	0.2	0.7	1.8	-0.8	-0.3	0.7	-1.1	-1.4	0.7	-0.7	-0.5	-1.2	-1.3	-0.6	-0.5	0.5
Diabetes (self-reported)	0.2	0.4	2.2	-0.4	-0.1	-0.1	-1.5	-0.5	-0.2	0.1	-0.3	0.0	-0.7	0.6	0.1	-1.1
Medication: Simvastatin	0.2	0.2	1.4	-0.2	0.0	-0.1	-0.1	-0.4	-0.9	0.1	-0.1	-0.3	0.3	1.2	-0.3	-0.6
Worrier / anxious feelings	0.2	0.3	1.9	0.5	0.3	0.8	0.5	0.3	-0.4	0.2	0.3	-0.5	-0.0	0.5	0.5	1.4
Hair/balding pattern: Pattern 3	0.2	0.4	1.6	0.2	-0.3	0.0	-0.1	0.0	0.5	-1.0	-0.1	-0.2	-0.4	-0.7	-1.0	-1.3
Medication: Lansoprazole	0.2	0.2	1.2	1.0	-0.0	-0.1	-0.1	0.1	-0.0	0.5	0.4	-0.6	1.1	0.4	0.2	-0.1
Birth weight of first child	0.2	0.4	2.4	1.6	0.7	-0.4	0.3	0.1	-0.6	0.4	0.2	0.9	0.1	-0.2	0.6	0.8
Peak expiratory flow (PEF)	0.2	0.4	1.1	0.5	0.5	1.0	0.3	-0.4	0.5	0.7	0.4	-0.6	-0.0	1.0	0.7	1.0
Blood clot in the leg (DVT)	0.2	0.3	1.2	0.3	-0.2	-0.1	0.7	0.0	-0.7	0.2	-0.1	1.1	-0.1	-0.3	0.3	-0.9
Medication: Paracetamol	0.2	0.3	0.6	0.5	-0.8	-0.4	-0.3	-0.6	-0.6	-0.3	-0.7	-0.6	0.1	-0.2	-0.3	-0.7
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	1.4	1.2	0.1	-0.2	0.7	0.4	0.9	0.3	0.2	0.8	0.7	-0.4	0.5	0.1
Medication: Amlodipine	0.2	0.3	1.7	0.6	-0.0	0.2	1.3	0.1	0.0	0.5	0.4	-0.1	0.1	-0.6	0.6	-0.6
Medication: Ventolin 100micrograms inhaler	0.2	0.2	1.4	-0.6	0.0	-0.4	0.2	0.4	-0.4	0.2	-0.1	1.2	-0.2	-0.5	0.5	0.6
High blood pressure (siblings)	0.2	0.3	2.6	-0.6	-0.3	-0.2	0.1	-0.2	-0.5	0.4	-0.2	0.4	1.6	0.6	0.0	0.6
Hypertension (Self-reported)	0.2	0.7	2.9	-0.7	0.4	0.7	0.0	0.6	-0.4	-1.0	0.6	-1.0	-0.2	0.3	-1.7	-1.4
Mood swings	0.2	0.3	0.9	-0.7	0.5	-0.2	0.9	0.7	0.8	-0.1	0.5	-0.6	0.5	0.0	0.1	0.9
Diabetes diagnosed by doctor	0.2	0.4	3.2	-0.4	0.1	0.4	-1.8	-0.2	-0.3	0.5	0.1	0.4	-0.3	0.8	0.6	-0.6
Illnesses of father: None of the above (group 1)	0.2	0.2	1.0	-0.5	0.0	0.3	0.1	-0.1	0.8	-0.3	-0.0	-0.5	-0.0	-1.0	0.0	0.8
Guilty feelings	0.2	0.3	0.9	-0.8	0.1	-0.2	0.7	0.2	0.2	-0.6	0.1	-0.9	0.3	-0.7	-0.6	0.2
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.8	-0.2	-0.3	-0.2	0.8	0.0	-0.5	0.2	-0.1	0.9	0.0	-0.5	0.4	-0.6
Blood Eosinophil Count	0.1	0.7	4.5	-0.5	-0.1	-0.1	-1.4	-0.2	-2.1	-0.6	-0.2	-0.7	-0.9	-0.1	-0.1	0.4
BMI	0.1	0.7	2.6	1.3	-0.3	-1.4	-1.6	-0.4	-0.3	0.5	-0.1	-0.9	0.1	0.6	0.7	0.8
Respiratory disease	0.1	0.3	0.9	0.9	0.6	0.8	-0.1	0.6	0.1	-0.4	0.6	-0.4	-0.1	0.5	-0.4	-0.2
Tanning	0.1	1.0	4.2	-0.0	-1.1	-1.0	1.0	-0.1	0.8	-1.6	-0.4	-0.9	0.4	-1.3	-2.0	0.5
Number of treatments/medications taken	0.1	0.2	0.7	-0.8	-0.2	-0.8	0.5	-0.3	-0.4	0.1	-0.0	0.2	0.4	0.0	-0.1	0.1
Serious illness, injury or assault to yourself	0.1	0.2	0.8	0.2	-0.3	-0.3	-0.3	-0.1	-0.0	-0.7	-0.2	-0.4	-0.2	-0.3	-0.9	-0.0
Trunk fat mass	0.1	0.3	1.6	1.2	0.1	-0.9	-0.2	-0.4	0.2	0.4	0.2	-0.4	0.2	0.0	0.5	0.6
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.7	-0.1	-0.2	-0.2	-0.3	0.3	0.8	0.1	-0.0	0.6	0.2	-0.4	0.0	-0.3
Neuroticism score	0.1	0.2	0.9	-0.8	-0.0	0.1	1.0	0.1	0.2	-0.5	-0.2	-0.1	-0.3	-0.6	-0.1	0.8
Arm fat percentage (right)	0.1	0.3	2.0	-0.4	-0.5	-1.4	-0.1	-0.2	0.2	-0.1	-0.1	-0.8	0.6	-0.1	-0.1	-0.1
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.5	-0.5	-0.3	0.3	-0.8	-1.2	0.3	-0.2	-0.3	-1.2	-0.5	-0.0	-0.1	0.8
Arm fat mass (right)	0.1	0.6	2.4	0.7	-0.8	-1.6	-1.2	-1.0	-0.4	0.0	-0.5	-0.7	-0.0	-0.3	0.3	0.1
Forced vital capacity (FVC), Best measure	0.1	0.2	0.7	0.3	-0.0	0.7	-0.1	-0.8	0.6	-0.2	-0.1	-0.6	-0.4	-0.4	-0.2	0.6
Body fat percentage	0.1	0.2	1.6	-0.2	-0.3	-1.3	0.0	-0.2	0.5	-0.3	-0.0	-0.7	0.4	-0.2	-0.3	0.3
Leg fat percentage (right)	0.1	0.3	1.9	0.0	-0.4	-1.4	-0.7	-0.4	0.1	-0.4	-0.3	-0.4	0.0	0.0	-0.2	0.2
Whole body fat mass	0.1	0.4	1.5	1.0	-0.4	-1.2	-1.0	-0.8	-0.1	0.1	-0.2	-0.5	0.0	-0.2	0.3	0.5
Leg fat mass (right)	0.1	0.6	2.2	1.1	-0.5	-1.5	-1.2	-0.9	-0.1	0.3	-0.4	-0.1	0.1	-0.2	0.7	0.8
Arm fat percentage (left)	0.1	0.3	2.0	-0.3	-0.5	-1.4	-0.2	-0.3	0.1	-0.2	-0.1	-0.9	0.4	-0.2	-0.1	-0.1
Arm fat mass (left)	0.1	0.4	1.5	1.0	-0.5	-1.2	-1.0	-0.7	-0.3	0.3	-0.2	-0.7	0.1	-0.1	0.6	0.3
Number of self-reported non-cancer illnesses	0.1	0.2	1.2	-1.1	0.6	0.2	0.2	0.6	-0.0	0.3	0.5	0.7	-0.2	0.2	0.3	-0.4
Medication: Paracetamol	0.1	0.2	0.9	0.4	-0.2	-0.5	-0.5	-0.3	-0.6	-0.2	-0.2	-0.9	-0.1	0.3	-0.2	-0.8
Ever smoked	0.1	0.2	0.6	0.5	0.2	0.2	0.8	-0.0	0.6	-0.1	0.1	0.2	0.4	-0.3	-0.4	-0.4
Leg fat percentage (left)	0.1	0.4	2.4	0.1	-0.7	-1.6	-0.5	-0.6	0.2	-0.6	-0.5	-0.7	0.3	-0.1	-0.5	0.0
Leg fat mass (left)	0.1	0.5	2.1	1.2	-0.5	-1.5	-1.0	-0.9	-0.0	0.2	-0.4	-0.2	0.2	-0.2	0.5	0.6
Hair Pigment	0.0	1.0	4.8	-0.4	1.3	1.5	-0.0	0.4	0.0	1.6	0.9	0.4	-0.3	0.7	2.2	0.2
Trunk fat percentage	0.0	0.2	0.9	-0.0	0.0	-0.9	0.5	0.1	0.6	-0.1	0.2	-0.7	0.4	-0.2	-0.2	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.2	0.8	-0.2	-0.1	0.1	-0.1	-0.7	0.4	0.2	-0.0	-0.7	-0.1	0.1	0.2	0.9

Hub : Genes

NUDT9

Models

Trait associations