Best TWAS P=1.41e-22 · Best GWAS P=5.83e-30 conditioned to 0.000643
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SNX24 | 0.11 | 0.00 | blup | 511 | 0.06 | 7.4e-08 | 0.31 | -5.4 | 5.9e-08 | 0.17 | 0.43 | 0.06 | TRUE |
| 2 | GTEx | Artery Aorta | CSNK1G3 | 0.11 | 0.07 | lasso | 2 | 0.01 | 6.5e-02 | -7.15 | -7.3 | 2.4e-13 | 0.52 | 0.15 | 0.09 | FALSE |
| 3 | GTEx | Artery Aorta | KRT8P33 | 0.10 | 0.04 | lasso | 6 | 0.05 | 9.1e-04 | -6.11 | 7.4 | 1.2e-13 | -0.62 | 0.04 | 0.85 | FALSE |
| 4 | GTEx | Esophagus Mucosa | CSNK1G3 | 0.14 | 0.05 | lasso | 3 | 0.07 | 2.0e-05 | 5.62 | 5.7 | 9.7e-09 | -0.44 | 0.79 | 0.10 | FALSE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CSNK1G3 | 0.04 | 0.02 | enet | 8 | 0.02 | 1.2e-04 | 5.41 | 7.9 | 3.3e-15 | -0.56 | 0.02 | 0.54 | FALSE |
| 6 | The Cancer Genome Atlas | Colon Adenocarcinoma | CEP120 | 0.06 | 0.02 | blup | 70 | 0.04 | 3.6e-03 | 7.59 | 8.9 | 6.5e-19 | -0.64 | 0.10 | 0.30 | FALSE |
| 7 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CEP120 | 0.03 | 0.02 | enet | 5 | 0.04 | 7.3e-05 | -6.11 | 9.3 | 1.4e-20 | -0.66 | 0.03 | 0.82 | TRUE |
| 8 | The Cancer Genome Atlas | Lung Adenocarcinoma | CSNK1G3 | 0.06 | 0.05 | lasso | 2 | 0.04 | 2.0e-05 | 5.62 | 5.5 | 3.1e-08 | -0.44 | 0.67 | 0.05 | FALSE |
| 9 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CEP120 | 0.10 | 0.14 | blup | 70 | 0.14 | 2.6e-14 | -10.97 | 9.8 | 1.4e-22 | -0.83 | 0.07 | 0.93 | TRUE |
| 10 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CSNK1G3 | 0.06 | 0.04 | enet | 10 | 0.05 | 2.3e-06 | 4.05 | 6.0 | 1.4e-09 | -0.57 | 0.43 | 0.48 | FALSE |